Research Topics
Species | Dewleen G BakerSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Higher levels of basal serial CSF cortisol in combat veterans with posttraumatic stress disorderDewleen G Baker
Psychiatry Service, San Diego VA Healthcare System, CA, USA
Am J Psychiatry 162:992-4. 2005..The authors' goal was to measure CSF cortisol concentrations, which more accurately reflect brain glucocorticoid exposure, in subjects with or without PTSD...
Altered amygdala activation during face processing in Iraqi and Afghanistani war veteransAlan N Simmons
Veterans Affairs San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
Biol Mood Anxiety Disord 1:6. 2011..abstract:..- Predictors of risk and resilience for posttraumatic stress disorder among ground combat Marines: methods of the Marine Resiliency StudyDewleen G Baker
VA Center for Stress and Mental Health 116A, VA San Diego Healthcare System, 3350 La Jolla Village Dr, San Diego, CA 92161, USA
Prev Chronic Dis 9:E97. 2012..Of enrolled Marines, approximately half (51.3%) had prior deployments. We found a moderate positive relationship between deployment history and PTSD prevalence in these baseline data... 
Biomarkers of PTSD: neuropeptides and immune signalingDewleen G Baker
Veterans Affairs Center of Excellence for Stress and Mental Health, VA San Diego, CA, USA
Neuropharmacology 62:663-73. 2012..Potential research implications and directions are discussed. This article is part of a Special Issue entitled 'Post-Traumatic Stress Disorder'...- Post-traumatic stress disorder: emerging concepts of pharmacotherapyDewleen G Baker
Department of Psychiatry, University of California San Diego, 9500 Gilman Drive 0603V, La Jolla, California 92093, USA
Expert Opin Emerg Drugs 14:251-72. 2009..Proven effective pharmacologic agents are sorely needed to treat core and targeted PTSD symptoms, and for prevention. This review describes current and emerging pharmacotherapies that advance these goals... - Psychological correlates of battle and nonbattle injury among Operation Iraqi Freedom veteransAndrew J MacGregor
Naval Health Research Center, San Diego, CA, USA
Mil Med 174:224-31. 2009..More research is needed to further define this relationship by examining potential mechanisms and addressing the possible contributing effect of combat exposure... - Prevalence and psychological correlates of traumatic brain injury in operation iraqi freedomAndrew J MacGregor
Naval Health Research Center, San Diego, California 92106, USA
J Head Trauma Rehabil 25:1-8. 2010..To describe the prevalence and psychological correlates of traumatic brain injury (TBI) among injured male combatants in the Iraq conflict... - An automatic MEG low-frequency source imaging approach for detecting injuries in mild and moderate TBI patients with blast and non-blast causesMing Xiong Huang
Radiology, Research, Rehab, and Psychiatry Services, VA San Diego Healthcare System, San Diego, CA, USA
Neuroimage 61:1067-82. 2012..This study provides a foundation for using MEG low-frequency source imaging to support the clinical diagnosis of TBI... - The role of emotional numbing in sexual functioning among veterans of the Iraq and Afghanistan warsSarah E Nunnink
Veterans Affairs Center of Excellence for Stress and Mental Health, 3350 La Jolla Village Drive, MC 116A, San Diego, CA 92161, USA
Mil Med 175:424-8. 2010..Those exhibiting numbing symptoms should be thoroughly assessed for sexual functioning problems and referred for treatment as necessary... - PTSD and depression as predictors of physical health-related quality of life in tobacco-dependent veteransLaura H Aversa
Veterans Affairs San Diego Healthcare System, 3350 La Jolla Village Dr 151, San Diego, CA 92161, USA
J Psychosom Res 73:185-90. 2012..Previous studies examining the effects of quitting smoking on HRQoL have been mixed. This study aimed to examine the effects of PTSD, depressive symptoms and smoking cessation on HRQoL in a sample receiving treatment for PTSD... - Low cerebrospinal fluid and plasma orexin-A (hypocretin-1) concentrations in combat-related posttraumatic stress disorderJeffrey R Strawn
Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, OH 45267 0559, USA
Psychoneuroendocrinology 35:1001-7. 2010.... - PTSD, combat injury, and headache in Veterans Returning from Iraq/AfghanistanNiloofar Afari
Department of Psychiatry, University of California, San Diego, San Diego, CA, USA
Headache 49:1267-76. 2009..To examine the relationship between posttraumatic stress disorder, combat injury, and headache in Operation Iraqi Freedom and Operation Enduring Freedom veterans at the VA San Diego Healthcare System... - Female veterans of the OEF/OIF conflict: concordance of PTSD symptoms and substance misuseSarah E Nunnink
Veterans Affairs Center of Excellence for Stress and Mental Health, 3350 La Jolla Village Drive MC 116A, San Diego, CA 92161, USA
Addict Behav 35:655-9. 2010..Future research should investigate needs for gender-specific PTSD and substance-abuse treatment needs... - Trauma exposure, branch of service, and physical injury in relation to mental health among U.S. veterans returning from Iraq and AfghanistanDewleen G Baker
University of California, San Diego, Department of Psychiatry, 9500 Gilman Dr, MC 0603 La Jolla, CA 92093 0603, USA
Mil Med 174:773-8. 2009..Follow-up analyses revealed that trauma history and combat exposure varied by branch of service. Knowledge of base rates and vulnerability factors can aid in rapid detection of "at risk" individuals... - The association of posttraumatic stress disorder and metabolic syndrome: a study of increased health risk in veteransPia S Heppner
Veterans Affairs San Diego Health Care System, Research Service, MC 151, La Jolla Village Drive, San Diego, CA 92161, USA
BMC Med 7:1. 2009..To assess PTSD-related biological burden, we measured biological factors that comprise metabolic syndrome, an important established predictor of morbidity and mortality, as a correlate of long-term health risk in PTSD... - Post-traumatic stress disorder, depression, and health-related quality of life in OEF/OIF veteransJames O E Pittman
Veterans Affairs Center of Excellence for Stress and Mental Health, 3350 La Jolla Village, Drive MC 116A, San Diego, CA 92161, USA
Qual Life Res 21:99-103. 2012..The study hypothesizes that PTSD and depression will each significantly predict lower physical and mental HRQoL even when controlling for overlapping symptoms: anhedonia, concentration, and insomnia... - Low cerebrospinal fluid neuropeptide Y concentrations in posttraumatic stress disorderRenu Sah
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45237, USA
Biol Psychiatry 66:705-7. 2009..Posttraumatic stress disorder (PTSD) is a stress-related anxiety disorder. We hypothesized that central nervous system NPY is dysregulated in PTSD and sought to redress the absence of central NPY data in the disorder... - The Peritraumatic Behavior Questionnaire: development and initial validation of a new measure for combat-related peritraumatic reactionsAgorastos Agorastos
Veterans Affairs Center of Excellence for Stress and Mental Health, VA San Diego, CA, USA
BMC Psychiatry 13:9. 2013..This study describes the development of the PBQ and reports on the psychometric properties of its self-rated version (PBQ-SR)... - Injury-specific predictors of posttraumatic stress disorderAndrew J MacGregor
Department of Medical Modeling, Simulation, and Mission Support, Naval Health Research Center, San Diego, CA 92106, USA
Injury 40:1004-10. 2009..The aim of this study was to characterise the relationship between injury-related factors and PTSD among a population of battle injuries... - Diminished vagal activity and blunted diurnal variation of heart rate dynamics in posttraumatic stress disorderAgorastos Agorastos
Veterans Affairs Center of Excellence for Stress and Mental Health, VA San Diego, CA, USA
Stress 16:300-10. 2013..Diminished diurnal differences and blunted tonic parasympathetic activity altering HR dynamics suggest central neuroautonomic dysregulation that could represent a possible link to increased cardiovascular disease in PTSD... - The influence of posttraumatic stress disorder numbing and hyperarousal symptom clusters in the prediction of physical health status in veterans with chronic tobacco dependence and posttraumatic stress disorderLaura H Harder
Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA
J Nerv Ment Dis 199:940-5. 2011..Our findings further explain the impact of PTSD on health status by exploring the way PTSD symptom clusters predict self-perceptions of health, role limitations, pain, and vitality... - Blood pressure and cerebrospinal fluid norepinephrine in combat-related posttraumatic stress disorderJeffrey R Strawn
Department of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA
Psychosom Med 66:757-9. 2004..Central nervous system norepinephrine (NE) is normally involved in blood pressure regulation, but it is pathophysiologically elevated in posttraumatic stress disorder (PTSD)... - Integrated imaging approach with MEG and DTI to detect mild traumatic brain injury in military and civilian patientsMing Xiong Huang
Research, Radiology, Rehabilitation, and Psychiatry Services, VA San Diego Healthcare System, San Diego, California, USA
J Neurotrauma 26:1213-26. 2009.... - Metabolic syndrome: relative risk associated with post-traumatic stress disorder (PTSD) severity and antipsychotic medication usePia S Heppner
Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA
Psychosomatics 53:550-8. 2012.... - Endocrine and cardiovascular responses to corticotropin-releasing hormone in patients with posttraumatic stress disorder: a role for atrial natriuretic peptide?Michael Kellner
Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
Neuropsychobiology 47:102-8. 2003..Further studies to assess ANP secretion in PTSD patients and to clarify its pathophysiological impact are needed... - Mineralocorticoid receptor function in patients with posttraumatic stress disorderMichael Kellner
Depatment of Psychiatry and Psychotherapy, University Hospital Hamburg-Eppendorf, Germany
Am J Psychiatry 159:1938-40. 2002..The study's experimental conditions did not allow determination of whether other compensatory factors might have masked the putative mineralocorticoid receptor changes... - Elevated cerebrospinal fluid substance p concentrations in posttraumatic stress disorder and major depressionThomas D Geracioti
Research Service, VA Medical Center, 3200 Vine St, Box 151, Cincinnati, OH 45220, USA
Am J Psychiatry 163:637-43. 2006..The authors also sought to determine if CNS substance P concentrations change on provocation of symptoms in PTSD patients... - Effects of trauma-related audiovisual stimulation on cerebrospinal fluid norepinephrine and corticotropin-releasing hormone concentrations in post-traumatic stress disorderThomas D Geracioti
Veterans Affairs Medical Center, Research Service, Cincinnati, OH, USA
Psychoneuroendocrinology 33:416-24. 2008.... - Review of assessment and treatment of PTSD among elderly American armed forces veteransGina P Owens
University of Kentucky, KY, USA
Int J Geriatr Psychiatry 20:1118-30. 2005..Limited data exist specifically related to prevalence, assessment, and treatment of PTSD among the elderly veteran population... - Mental health of US Gulf War veterans 10 years after the warRosemary Toomey
Toomey, Psychology Department, Boston University, 648 Beacon Street, 6th Floor, Boston, MA 02215, USA
Br J Psychiatry 190:385-93. 2007..Gulf War veterans reported multiple psychological symptoms immediately after the war; the temporal course of these symptoms remains unclear... - Evaluation of the Mississippi PTSD Scale--Revised using Rasch measurementElizabeth Betemps
University of Cincinnati, P O Box 210038, Cincinnati, Ohio 45221, USA
Ment Health Serv Res 6:117-25. 2004..These items may be used to develop an interval scale of the PTSD construct that is generalizable across diverse populations and that can be used for individualized comparable assessments... - Randomized, double-blind comparison of sertraline and placebo for posttraumatic stress disorder in a Department of Veterans Affairs settingMatthew J Friedman
Department of Veterans Affairs, National Center for Posttraumatic Stress Disorder, White River Junction, VT 05009, USA
J Clin Psychiatry 68:711-20. 2007..To evaluate the efficacy of sertraline in the treatment of posttraumatic stress disorder (PTSD) in a Veterans Affairs (VA) clinic setting involving patients with predominantly combat-related PTSD... - Measurement precision of the clinician administered PTSD scale (CAPS): a RASCH model analysisElizabeth J Betemps
University of Cincinnati, PO Box 210038, Cincinnati, Ohio 45221 0038, USA
J Appl Meas 4:59-69. 2003..Items from this instrument can be used to develop an equal interval scale to provide precise measurements for treatment evaluations and to identify clinical cut points for diagnostic purposes... - Post-traumatic stress disorder and smoking: a systematic reviewSteven S Fu
Center for Chronic Disease Outcomes Research, Veterans Affairs Medical Center, and Department of Medicine, University of Minnesota, Minneapolis, MN, USA
Nicotine Tob Res 9:1071-84. 2007..Intervention studies that test behavioral and pharmacological interventions designed specifically for use in patients with PTSD are needed to reduce morbidity and mortality in this population... - Correlates for posttraumatic stress disorder in Gulf War veterans: a retrospective study of main and moderating effectsAmanda L Stein
Department of Psychology, University of Cincinnati, P O Box 210376, Cincinnati, OH 45221 0376, USA
J Anxiety Disord 19:861-76. 2005..Study findings have implications for longitudinal investigation of PTSD development and preventive interventions...