Lynn B Bailey

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi request reprint Vitamin B-12 status is inversely associated with plasma homocysteine in young women with C677T and/or A1298C methylenetetrahydrofolate reductase polymorphisms
    Lynn B Bailey
    Food Science and Human Nutrition Department, and Department of Statistics, University of Florida, Gainesville 32611, USA
    J Nutr 132:1872-8. 2002
  2. ncbi request reprint Folic acid supplementation and the occurrence of congenital heart defects, orofacial clefts, multiple births, and miscarriage
    Lynn B Bailey
    Food Science and Human Nutrition Department, University of Florida, Gainesville, FL 32611, USA
    Am J Clin Nutr 81:1213S-1217S. 2005
  3. ncbi request reprint Folic acid supplements and fortification affect the risk for neural tube defects, vascular disease and cancer: evolving science
    Lynn B Bailey
    Food Science and Human Nutrition Department, University of Florida, Gainesville, FL 32611 0370, USA
    J Nutr 133:1961S-1968S. 2003
  4. ncbi request reprint Folate, methyl-related nutrients, alcohol, and the MTHFR 677C-->T polymorphism affect cancer risk: intake recommendations
    Lynn B Bailey
    Food Science and Human Nutrition Department, University of Florida, Gainesville, FL 32611, USA
    J Nutr 133:3748S-3753S. 2003
  5. ncbi request reprint Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women
    Steven R Davis
    Food Science and Human Nutrition Department, Institute of Food and Agricultural Sciences, College of Medicine, University of Florida, Gainesville 32611 0370, USA
    J Nutr 135:1045-50. 2005
  6. ncbi request reprint Methionine synthase reductase 66A->G polymorphism is associated with increased plasma homocysteine concentration when combined with the homozygous methylenetetrahydrofolate reductase 677C->T variant
    Jaimie D Vaughn
    Food Science and Human Nutrition Department, University of Florida, Gainesville, FL 32611, USA
    J Nutr 134:2985-90. 2004
  7. ncbi request reprint The methylenetetrahydrofolate reductase 677C->T polymorphism and dietary folate restriction affect plasma one-carbon metabolites and red blood cell folate concentrations and distribution in women
    Steven R Davis
    Food Science and Human Nutrition Department, Institute of Food and Agricultural Sciences, College of Medicine, University of Florida, Gainesville, FL 32611 0370, USA
    J Nutr 135:1040-4. 2005
  8. ncbi request reprint Methylenetetrahydrofolate reductase 677C-->T polymorphism affects DNA methylation in response to controlled folate intake in young women
    Karla P Shelnutt
    Department of Food Science and Human Nutrition, University of Florida, Gainesville, FL 32611, USA
    J Nutr Biochem 15:554-60. 2004
  9. ncbi request reprint Transcobalamin 776C->G polymorphism negatively affects vitamin B-12 metabolism
    Kristina M von Castel-Dunwoody
    Food Science and Human Nutrition Department and the General Clinical Research Center, University of Florida, Gainesville, FL 32611, USA
    Am J Clin Nutr 81:1436-41. 2005
  10. ncbi request reprint Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides
    Eoin P Quinlivan
    Food Science and Human Nutrition Department, Institute of Food and Agricultural Sciences, College of Medicine, University of Florida, Gainesville, FL 32611, USA
    J Nutr 135:389-96. 2005

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Vitamin B-12 status is inversely associated with plasma homocysteine in young women with C677T and/or A1298C methylenetetrahydrofolate reductase polymorphisms
    Lynn B Bailey
    Food Science and Human Nutrition Department, and Department of Statistics, University of Florida, Gainesville 32611, USA
    J Nutr 132:1872-8. 2002
    ..These data suggest that enhancing vitamin B-12 status may significantly decrease homocysteine in young women with C677T and/or A1298C MTHFR polymorphisms, even when vitamin B-12 concentrations are within the normal range...
  2. ncbi request reprint Folic acid supplementation and the occurrence of congenital heart defects, orofacial clefts, multiple births, and miscarriage
    Lynn B Bailey
    Food Science and Human Nutrition Department, University of Florida, Gainesville, FL 32611, USA
    Am J Clin Nutr 81:1213S-1217S. 2005
    ..All women capable of becoming pregnant should continue to consume 400 mug/d of folic acid in addition to a healthy diet as advised...
  3. ncbi request reprint Folic acid supplements and fortification affect the risk for neural tube defects, vascular disease and cancer: evolving science
    Lynn B Bailey
    Food Science and Human Nutrition Department, University of Florida, Gainesville, FL 32611 0370, USA
    J Nutr 133:1961S-1968S. 2003
    ..The potential for folic acid supplements to reduce the incidence and severity of vascular disease and cancer is the focus of major research efforts including ongoing intervention studies...
  4. ncbi request reprint Folate, methyl-related nutrients, alcohol, and the MTHFR 677C-->T polymorphism affect cancer risk: intake recommendations
    Lynn B Bailey
    Food Science and Human Nutrition Department, University of Florida, Gainesville, FL 32611, USA
    J Nutr 133:3748S-3753S. 2003
    ..The negative effects of low intakes of the methyl-related nutrients with high intakes of alcohol are additive, therefore changes in overall dietary patterns to ensure the consumption of a protective high methyl diet are recommended...
  5. ncbi request reprint Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women
    Steven R Davis
    Food Science and Human Nutrition Department, Institute of Food and Agricultural Sciences, College of Medicine, University of Florida, Gainesville 32611 0370, USA
    J Nutr 135:1045-50. 2005
    ..In conclusion, elevated homocysteine synthesis is a cause of mild hyperhomocysteinemia in women with marginal folate status, particularly those with the MTHFR 677 T/T genotype...
  6. ncbi request reprint Methionine synthase reductase 66A->G polymorphism is associated with increased plasma homocysteine concentration when combined with the homozygous methylenetetrahydrofolate reductase 677C->T variant
    Jaimie D Vaughn
    Food Science and Human Nutrition Department, University of Florida, Gainesville, FL 32611, USA
    J Nutr 134:2985-90. 2004
    ....
  7. ncbi request reprint The methylenetetrahydrofolate reductase 677C->T polymorphism and dietary folate restriction affect plasma one-carbon metabolites and red blood cell folate concentrations and distribution in women
    Steven R Davis
    Food Science and Human Nutrition Department, Institute of Food and Agricultural Sciences, College of Medicine, University of Florida, Gainesville, FL 32611 0370, USA
    J Nutr 135:1040-4. 2005
    ....
  8. ncbi request reprint Methylenetetrahydrofolate reductase 677C-->T polymorphism affects DNA methylation in response to controlled folate intake in young women
    Karla P Shelnutt
    Department of Food Science and Human Nutrition, University of Florida, Gainesville, FL 32611, USA
    J Nutr Biochem 15:554-60. 2004
    ..The response to folate repletion suggests that following folate depletion women with the MTHFR 677 TT genotype have a greater increase in DNA methylation with folate repletion than women with the CC genotype...
  9. ncbi request reprint Transcobalamin 776C->G polymorphism negatively affects vitamin B-12 metabolism
    Kristina M von Castel-Dunwoody
    Food Science and Human Nutrition Department and the General Clinical Research Center, University of Florida, Gainesville, FL 32611, USA
    Am J Clin Nutr 81:1436-41. 2005
    ..Remethylation of homocysteine is dependent on the production of 5-methyltetrahydrofolate and adequate vitamin B-12 for the methionine synthase reaction...
  10. ncbi request reprint Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides
    Eoin P Quinlivan
    Food Science and Human Nutrition Department, Institute of Food and Agricultural Sciences, College of Medicine, University of Florida, Gainesville, FL 32611, USA
    J Nutr 135:389-96. 2005
    ..These findings support the feasibility of further assessment of factors affecting deoxynucleotide synthesis and DNA methylation in human 1-carbon metabolism...
  11. ncbi request reprint Folate status response to controlled folate intake is affected by the methylenetetrahydrofolate reductase 677C-->T polymorphism in young women
    Karla P Shelnutt
    Food Science and Human Nutrition Department, University of Florida, Gainesville, FL 32611, USA
    J Nutr 133:4107-11. 2003
    ..These results may be important when evaluating the impact of the MTHFR 677C-->T polymorphism in countries in which low folate diets are chronically consumed...
  12. ncbi request reprint Folate: a key to optimizing health and reducing disease risk in the elderly
    Gail C Rampersaud
    Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida 32611, USA
    J Am Coll Nutr 22:1-8. 2003
    ..Folate-rich foods include orange juice, dark green leafy vegetables, asparagus, strawberries and legumes. These foods are also excellent sources of other health-promoting nutrients associated with chronic disease risk reduction...
  13. pmc Hypomethylation of serum blood clot DNA, but not plasma EDTA-blood cell pellet DNA, from vitamin B12-deficient subjects
    Eoin P Quinlivan
    Biomedical Mass Spectrometry Laboratory, Clinical and Translational Science Institute, University of Florida, Gainesville, Florida, United States of America
    PLoS ONE 8:e65241. 2013
    ..These findings highlight the importance of sample collection methods in epigenetic studies, and the potential impact biological processes can have on DNA methylation during collection...
  14. ncbi request reprint Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor
    Steven R Davis
    Food Science and Human Nutrition Department, Institute of Food and Agricultural Science, University of Florida, Gainesville, Florida 32611 0370, USA
    Am J Physiol Endocrinol Metab 286:E272-9. 2004
    ..Our dual-tracer procedure is well suited to measure the effects of nutrient deficiencies, genetic polymorphisms, and other metabolic perturbations on homocysteine synthesis and total and folate-dependent homocysteine remethylation...
  15. ncbi request reprint Holo-transcobalamin is an indicator of vitamin B-12 absorption in healthy adults with adequate vitamin B-12 status
    Kristina M von Castel-Roberts
    Departments of Food Science and Human Nutrition, University of Florida, Gainesville, USA
    Am J Clin Nutr 85:1057-61. 2007
    ..To develop a reliable clinical absorption test that uses holo-TC, it is necessary to determine the optimal timeline for vitamin B-12 administration and postdose assessment...
  16. ncbi request reprint Folate catabolite excretion is responsive to changes in dietary folate intake in elderly women
    Judith M Wolfe
    Food Science and Human Nutrition Department, College of Agricultural and Life Sciences, University of Florida, Gainesville 32611, USA
    Am J Clin Nutr 77:919-23. 2003
    ..We hypothesize that total pABG (ApABG + pABG) excretion parallels both the mass of body folate pools from which these catabolites originate and the folate-status indicators...
  17. doi request reprint Oral contraceptive use: impact on folate, vitamin B₆, and vitamin B₁₂ status
    Stephanie M C Wilson
    University of Florida, Gainesville, Florida, USA
    Nutr Rev 69:572-83. 2011
    ..Functional indicators of vitamin B₁₂ status are not significantly impacted by OC use. Definitive conclusions, however, await further investigations...
  18. ncbi request reprint National survey beverage consumption data for children and adolescents indicate the need to encourage a shift toward more nutritive beverages
    Gail C Rampersaud
    Nutrition Research and Education, Food Science and Human Nutrition Department, University of Florida, Gainesville 32611, USA
    J Am Diet Assoc 103:97-100. 2003
    ..Increased consumption of nutrient-dense beverages (100% fruit juice, milk) and water as part of a varied diet should be encouraged...
  19. ncbi request reprint Folate and vitamin B12 recommended intakes and status in the United States
    Lynn B Bailey
    University of Florida, Food Science and Human Nutrition Department, FSHN Bldg, Gainesville, FL 32611 0370, USA
    Nutr Rev 62:S14-20; discussion S21. 2004
    ..Recently reported evidence of vitamin B12 inadequacy in the aging segment of the U.S. population will be addressed...
  20. ncbi request reprint Relationship of folate to colorectal and cervical cancer: review and recommendations for practitioners
    Gail C Rampersaud
    Food Science and Human Nutrition Department, Food and Environmental Toxicology Laboratory, University of Florida, Box 110720, Bldg 685, SW 23rd Drive, Gainesville, FL 32611 0720, USA
    J Am Diet Assoc 102:1273-82. 2002
    ..People consuming alcohol on a daily basis may especially benefit from additional folate in their diets...
  21. ncbi request reprint Consumption of folic acid-fortified bread improves folate status in women of reproductive age in Chile
    Eva Hertrampf
    Institute of Nutrition and Food Technology, University of Chile, Macul 5540, Santiago, Chile
    J Nutr 133:3166-9. 2003
    ..Fortification of wheat flour substantially improved folate status in a population of women of reproductive age in Chile. The effect of the FA fortification program on the occurrence of NTD is currently being assessed...
  22. ncbi request reprint The rise and fall of blood folate in the United States emphasizes the need to identify all sources of folic acid
    Lynn B Bailey
    Am J Clin Nutr 86:528-30. 2007
  23. ncbi request reprint Folate status and homocysteine response to folic acid doses and withdrawal among young Chinese women in a large-scale randomized double-blind trial
    Ling Hao
    National Reference Laboratory on Reproductive and Child Health, Ministry of Health and National Center for Maternal and Infant Health, Peking University Health Science Center, Beijing, China
    Am J Clin Nutr 88:448-57. 2008
    ..There are no large randomized trials of the effect of folic acid dosing regimens on blood folate and homocysteine concentrations...
  24. ncbi request reprint Do low doses of folic acid result in maximum lowering of homocysteine?
    Lynn B Bailey
    Am J Clin Nutr 82:717-8. 2005
  25. ncbi request reprint Consumption of the folate breakdown product para-aminobenzoylglutamate contributes minimally to urinary folate catabolite excretion in humans: investigation using [(13)C(5)]para-aminobenzoylglutamate
    Marie A Caudill
    Human Nutrition and Food Science Department, Cal Poly Pomona University, Pomona, CA 91768, USA
    J Nutr 132:2613-6. 2002
    ..Overall, these results suggest that the contribution of dietary pABG to the urinary excretion of pABG and apABG is small...