Research Topics
| H H BaileySummaryAffiliation: University of Wisconsin Country: USA Publications
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Publications
A phase II trial of daily perillyl alcohol in patients with advanced ovarian cancer: Eastern Cooperative Oncology Group Study E2E96Howard H Bailey
University of Wisconsin Madison, Madison, Wisconsin 53792, USA
Gynecol Oncol 85:464-8. 2002..Perillyl alcohol was administered orally, four times daily, at a dose of 1200 mg/m(2). This was repeated until disease progression or unacceptable toxicity was experienced...
A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 daysHoward H Bailey
University of Wisconsin Comprehensive Cancer Center, K6 568 CSC, 600 Highland Avenue, Madison, WI 53792 5669, USA
Cancer Chemother Pharmacol 54:368-76. 2004..A phase I study of POH for 14 days out of every 28 days in subjects with advanced malignancies was performed to evaluate dose escalation, toxicity, pharmacokinetics, and effects on TGFbeta and Ras...
Phase I study of continuous-infusion L-S,R-buthionine sulfoximine with intravenous melphalanH H Bailey
Department of Medicine, University of Wisconsin Comprehensive Cancer Center, Madison 53792, USA
J Natl Cancer Inst 89:1789-96. 1997....
L-S,R-buthionine sulfoximine: historical development and clinical issuesH H Bailey
University of Wisconsin Comprehensive Cancer Center, Department of Medicine, Madison 53792, USA
Chem Biol Interact 111:239-54. 1998..Evidence of clinical activity has been observed in patients with alkylating or platinating agent-refractory tumors. Phase II evaluation of CI BSO with L-PAM is in progress...
Phase II trial of daily oral perillyl alcohol (NSC 641066) in treatment-refractory metastatic breast cancerHoward H Bailey
University of Wisconsin Paul P Carbone Comprehensive Cancer Center, 600 Highland Avenue K4 6 CSC, Madison, WI 53792, USA
Cancer Chemother Pharmacol 62:149-57. 2008..We conducted a phase II multi-institutional study of oral POH administered four times daily in women with advanced treatment-refractory breast cancer...
Green tea polyphenols for prostate cancer chemoprevention: a translational perspectiveJ J Johnson
University of Wisconsin School of Pharmacy, Division of Pharmacy Practice, 1031 Rennebohm Hall, Madison, WI, USA
Phytomedicine 17:3-13. 2010..The data that has been collected so far suggests that green tea may be a promising agent for PCa chemoprevention and further clinical trials of participants at risk of PCa or early stage PCa are warranted...
Weekly docetaxel and carboplatin for recurrent ovarian and peritoneal cancer: a phase II trialDavid M Kushner
Division of Gynecologic Oncology, University of Wisconsin Paul P Carbone Comprehensive Cancer Center, Madison, and Regional Cancer Center at Oconomowoc Waukesha Memorial Hospitals, WI, USA
Gynecol Oncol 105:358-64. 2007..The optimal specific combination has yet to be determined. The current study evaluates weekly docetaxel and carboplatin in this setting...
Phase II study of daily oral perifosine in patients with advanced soft tissue sarcomaHoward H Bailey
University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin 53792, USA
Cancer 107:2462-7. 2006....
Phase II study of weekly low-dose paclitaxel for relapsed and refractory non-Hodgkin's lymphoma: a Wisconsin Oncology Network StudyBrad S Kahl
Department of Medicine, University of Wisconsin Comprehensive Cancer Center, University of Wisconsin Medical School, Madison, WI 53792, USA
Cancer Invest 23:13-8. 2005..The response rate appears similar to other reports using different doses and schedules. Myelosuppression appears less with this schedule than with other schedules...
Dose-escalation study of fixed-dose rate gemcitabine combined with capecitabine in advanced solid malignanciesSteven Attia
University of Wisconsin Paul P Carbone Comprehensive Cancer Center Madison, Madison, WI 53792, USA
Cancer Chemother Pharmacol 64:45-51. 2009..To define dose limiting toxicities (DLTs) and the maximum tolerated dose (MTD) of capecitabine with fixed-dose rate (FDR) gemcitabine...
A randomized, double-blind, placebo-controlled phase 3 skin cancer prevention study of {alpha}-difluoromethylornithine in subjects with previous history of skin cancerHoward H Bailey
University of Wisconsin Paul P Carbone Cancer Center, Madison, USA
Cancer Prev Res (Phila) 3:35-47. 2010..069) in new NMSC that was predominantly due to a marked reduction in new BCC. Based on these data, the potential of DFMO, alone or in combination, to prevent skin cancers should be explored further...
Phase I clinical and pharmacokinetic trial of the cyclin-dependent kinase inhibitor flavopiridolJames P Thomas
University of Wisconsin Comprehensive Cancer Center, University of Wisconsin Medical School, 600 Highland Ave, Madison, WI 53792, USA
Cancer Chemother Pharmacol 50:465-72. 2002..The manageable gastrointestinal toxicity, early signs of clinical activity and lack of hematologic toxicity make further exploration in combination trials warranted...
Phase I trial of motexafin gadolinium and doxorubicin in the treatment of advanced malignanciesAnne M Traynor
University of Wisconsin Paul P Carbone Comprehensive Cancer Center, Madison, WI 53792, USA
Invest New Drugs 29:316-22. 2011..To assess the safety, maximum-tolerated dose (MTD), and dose-limiting toxicities (DLT), of motexafin gadolinium (MGd), given in combination with doxorubicin, in patients with advanced solid tumors...
Phase I trial of weekly paclitaxel and BMS-214662 in patients with advanced solid tumorsHoward H Bailey
University of Wisconsin Paul P Carbone Comprehensive Cancer Center, Madison, Wisconsin 53792, USA
Clin Cancer Res 13:3623-9. 2007..To assess the maximum tolerated dose (MTD), dose-limiting toxicity (DLT), pharmacodynamics, and antitumor activity of continuous weekly-administered paclitaxel and BMS-214662, a novel farnesyl transferase inhibitor...
Gemcitabine, Paclitaxel, and piritrexim: a phase I studyGlenn Liu
University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, USA
Am J Clin Oncol 26:280-4. 2003..The combination of these new antifolates with paclitaxel and gemcitabine appears safe and should be considered for phase II trials in known responsive tumors such as transitional cell carcinomas...
Phase II study of arsenic trioxide and ascorbic acid for relapsed or refractory lymphoid malignancies: a Wisconsin Oncology Network studyJ E Chang
Paul P Carbone Comprehensive Cancer Center, University of Wisconsin, Madison, WI, USA
Hematol Oncol 27:11-6. 2009..As(2)O(3) and AA in this novel dosing strategy was generally well tolerated but had limited activity in patients with relapsed and refractory lymphoid malignancies...
Maintenance rituximab following induction chemoimmunotherapy may prolong progression-free survival in mantle cell lymphoma: a pilot study from the Wisconsin Oncology NetworkB S Kahl
Department of Medicine, University of Wisconsin, Madison, WI, USA
Ann Oncol 17:1418-23. 2006..There is no standard first line treatment for mantle cell lymphoma...
Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequenceR T Mulcahy
Department of Human Oncology, University of Wisconsin Medical School, Madison, Wisconsin 53792, USA
J Biol Chem 272:7445-54. 1997..Collectively the data indicate that the constitutive and beta-NF-induced expression of the human GCS heavy subunit gene is mediated by a distal ARE sequence containing an embedded tetradecanoylphorbol-13-acetate-responsive element...
Non-Hodgkin's lymphoma presenting as a pelvic mass with elevated CA-125Gregory W Allen
Department of Human Oncology, University of Wisconsin Hospital and Clinics, Madison, WI 53792, USA
Gynecol Oncol 94:811-3. 2004..While ovarian cancer is high on the list of differential diagnoses, lymphoma cannot be excluded until a tissue diagnosis is obtained...
Progress of a Comprehensive Familial Cancer Genetic Counseling Program in the Era of BRCA1 and BRCA2Ellen M Hartenbach
University of Wisconsin Comprehensive Cancer Center, Gynecologic Oncology Program, Madison 53792, USA
Genet Test 6:75-8. 2002..In our program, the majority of families counseled were eligible for BRCA1/BRCA2 testing, but only 18% have elected to proceed at this time...
Phase II study of 1alpha-hydroxyvitamin D(2) in the treatment of advanced androgen-independent prostate cancerGlenn Liu
Department of Medicine, Medical Oncology Section, University of Wisconsin Comprehensive Cancer Center, 600 Highland Avenue, Madison, WI 53792, USA
Clin Cancer Res 9:4077-83. 2003..CONCLUSION: The results of this and other trials suggest further clinical investigation in this disease with vitamin D analogues alone or in combination with other agents, such as chemotherapy, should be pursued...
A phase I trial of intraperitoneal sustained-release paclitaxel microspheres (Paclimer) in recurrent ovarian cancer: a Gynecologic Oncology Group studyDeborah K Armstrong
John Hopkins Kimmel Cancer Center, Bunting Blaustein Cancer Research Building, Baltimore, MD 21231 1000, USA
Gynecol Oncol 103:391-6. 2006..The goals of this phase I study were to determine the maximum tolerated dose (MTD) of IP paclitaxel microspheres and the pharmacology of paclitaxel after IP paclitaxel microsphere administration...
