Research Topics
Species | C A BaileSummaryAffiliation: University of Georgia Country: USA Publications
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Detail Information
Publications
Regulation of metabolism and body fat mass by leptinC A Baile
Department of Animal and Dairy Science, University of Georgia, Athens Georgia 30602, USA
Annu Rev Nutr 20:105-27. 2000....
Novel treatments for obesity and osteoporosis: targeting apoptotic pathways in adipocytesC Nelson-Dooley
Departments of Animal and Dairy Sciences, University of Georgia, Athens, GA, USA
Curr Med Chem 12:2215-25. 2005....
TNFalpha induces and insulin inhibits caspase 3-dependent adipocyte apoptosisH Qian
Department of Foods and Nutrition, University of Georgia, Athens, Georgia 30602, USA
Biochem Biophys Res Commun 284:1176-83. 2001..These data suggest that adipose tissue cell number is regulated, in part, by an apoptotic signaling pathway that involves TNFalpha, insulin, and caspase 3...
Inhibition of preadipocyte differentiation by myostatin treatment in 3T3-L1 culturesH S Kim
Department of Animal and Dairy Science, University of Georgia, Athens, Georgia 30602, USA
Biochem Biophys Res Commun 281:902-6. 2001..Our data show that Myostatin, a secreted protein from muscle, inhibits preadipocyte differentiation in 3T3-L1 cells, which is mediated, in part, by altered regulation of C/EBP alpha and PPAR gamma...
Ciliary neurotrophic factor injected icv induces adipose tissue apoptosis in ratsE Duff
Departments of Food and Nutrition, University of Georgia, Athens GA 30602, USA
Apoptosis 9:629-34. 2004..05) and in Rp by 121 and 146%, respectively ( p <.05). Loss of adipocytes by apoptosis may provide an explanation for the unexpected delay in return to initial energy status following CNTF treatments...
Metabolic responses to intracerebroventricular leptin and restricted feedingT Wang
Department of Animal Science, The University of Georgia, Athens 30602, USA
Physiol Behav 65:839-48. 1999..Conversely, leptin treatment has prolonged effects on body weight resulting from different metabolic responses than food restriction. Leptin not only suppresses food intake, but also enhances energy expenditure to reduce fat depots...
Intracerebroventricular (i.c.v.) administration of mouse leptin in rats: behavioral specificity and effects on meal patternsM G Hulsey
Department of Foods and Nutrition, The University of Georgia, Athens 30602, USA
Physiol Behav 65:445-55. 1998..c.v.) significantly increased intermeal interval and decreased meal size. We, therefore, conclude that mouse leptin, at doses up to 30 microg i.c.v., is not aversive in the rat, and that leptin has a multiphasic effect on meal patterns...
Responses of lean and obese Zucker rats to centrally administered leptinT Wang
Department of Foods and Nutrition, The University of Georgia, Athens 30602, USA
Physiol Behav 65:333-41. 1998..After withdrawal of daily leptin treatment, lean and obese Zucker rats exhibited different recovery responses. It is concluded that obese Zucker rats can respond to exogenous leptin when leptin is delivered into the brain ventricles...
25-hydroxyvitamin D, insulin-like growth factor-I, and bone mineral accrual during growthM E Breen
Department of Foods and Nutrition, The University of Georgia, Athens, Georgia 30602, USA
J Clin Endocrinol Metab 96:E89-98. 2011..OBJECTIVE, SETTING, AND PARTICIPANTS: This study sought to determine relationships among 25(OH)D, IGF-I, and BMC in community-dwelling prepubertal females (n = 76; aged 4-8 yr at baseline) over a period of up to 9 yr...
Glucagon-like peptide-1 (7-36) amide administered into the third cerebroventricle inhibits water intake in ratsT Wang
Department of Animal Science, The University of Georgia, Athens 30602, USA
Proc Soc Exp Biol Med 219:85-91. 1998..These observations indicate that GLP-1 is a potent inhibitor of water intake in the rat and may play a role in the control of fluid homeostasis...
GIP-dependent expression of hypothalamic genesS Ambati
Department of Animal and Dairy Science, University of Georgia, Athens, GA 30602 2771, USA
Physiol Res 60:941-50. 2011..1±7.5 %), CART (28.3±3.7 %), OXT (25.2±5.8 %), PTGES (23.9±4.5 %), and STAT3 (8.8±2.3 %). These results suggest that AVP, CART, OXT and STAT3 may be involved in energy balance-related hypothalamic circuits affected by GIP...
CART deficiency increases body weight but does not alter bone strengthS M Bartell
Animal and Dairy Science, University of Georgia, Athens, GA, USA
J Musculoskelet Neuronal Interact 8:146-53. 2008..Our data suggest that while the central, neuroendocrine regulation of bone mass via CART signaling may have effects on trabecular mass, absence of CART expression does not significantly alter cortical bone geometry, density, or strength...
Leptin-induced adipose apoptosis: Implications for body weight regulationP S Gullicksen
Department of Animal and Dairy Science, University of Georgia, Athens, GA 30602, USA
Apoptosis 8:327-35. 2003..This review summarizes the major aspects of leptin-induced adipose tissue apoptosis, including some of the newest findings about possible mechanisms of action...
Evaluation of adipocyte apoptosis by laser scanning cytometryJ Lin
Department of Animal and Dairy Science, University of Georgia, Athens, GA 30602-2771, USA
Int J Obes Relat Metab Disord 28:1535-40. 2004..CONCLUSION: With morphological information, LSC can be a useful tool to evaluate adipocyte apoptosis...
