Herwig Baier

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Genetic and optical targeting of neural circuits and behavior--zebrafish in the spotlight
    Herwig Baier
    University of California, San Francisco, Department of Physiology, San Francisco, CA 94158 2324, USA
    Curr Opin Neurobiol 19:553-60. 2009
  2. pmc The cellular architecture of the larval zebrafish tectum, as revealed by gal4 enhancer trap lines
    Ethan K Scott
    Department of Physiology, University of California San Francisco, CA, USA
    Front Neural Circuits 3:13. 2009
  3. pmc Non-SMC condensin I complex proteins control chromosome segregation and survival of proliferating cells in the zebrafish neural retina
    Sabine Seipold
    Max Delbruck Center MDC for Molecular Medicine, Berlin, Germany
    BMC Dev Biol 9:40. 2009
  4. pmc Regulation of neurogenesis by interkinetic nuclear migration through an apical-basal notch gradient
    Filippo Del Bene
    Department of Physiology, Programs in Neuroscience, Genetics, and Developmental Biology, University of California San Francisco, San Francisco, CA 94158 2722, USA
    Cell 134:1055-65. 2008
  5. pmc Filtering of visual information in the tectum by an identified neural circuit
    Filippo Del Bene
    Department of Physiology, University of California, San Francisco, CA 94158, USA
    Science 330:669-73. 2010
  6. pmc Forward genetic analysis of visual behavior in zebrafish
    Akira Muto
    Department of Physiology, Programs in Neuroscience, Genetics, and Developmental Biology, Center for Human Genetics, University of California, San Francisco, California, United States of America
    PLoS Genet 1:e66. 2005
  7. pmc A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos
    Suk Won Jin
    Department of Biochemistry and Biophysics, Genetics and Human Genetics, and Cardiovascular Research Institute, University of California San Francisco, CA 94158, USA
    Dev Biol 307:29-42. 2007
  8. ncbi request reprint A GFP-based genetic screen reveals mutations that disrupt the architecture of the zebrafish retinotectal projection
    Tong Xiao
    Department of Physiology, University of California, San Francisco, Programs in Neuroscience, Genetics, Human Genetics, and Developmental Biology, 1550 4th Street, San Francisco, CA 94158 2722, USA
    Development 132:2955-67. 2005
  9. pmc Genetic and physiologic dissection of the vertebrate cardiac conduction system
    Neil C Chi
    Department of Biochemistry and Biophysics and Programs in Developmental Biology, Genetics, and Human Genetics, University of California San Francisco, San Francisco, California, United States of America
    PLoS Biol 6:e109. 2008
  10. pmc Optogenetic localization and genetic perturbation of saccade-generating neurons in zebrafish
    Peter J Schoonheim
    Department of Physiology, Programs in Neuroscience, Genetics and Developmental Biology, University of California, San Francisco, San Francisco, California 94158 2324, USA
    J Neurosci 30:7111-20. 2010

Collaborators

Detail Information

Publications51

  1. pmc Genetic and optical targeting of neural circuits and behavior--zebrafish in the spotlight
    Herwig Baier
    University of California, San Francisco, Department of Physiology, San Francisco, CA 94158 2324, USA
    Curr Opin Neurobiol 19:553-60. 2009
    ..Because the manipulation is restricted to times and places where genetics (cell types) and optics (beams of light) intersect, this method affords excellent resolving power for the functional analysis of neural circuitry...
  2. pmc The cellular architecture of the larval zebrafish tectum, as revealed by gal4 enhancer trap lines
    Ethan K Scott
    Department of Physiology, University of California San Francisco, CA, USA
    Front Neural Circuits 3:13. 2009
    ..Such detailed anatomical descriptions will be an important part of future efforts to describe the functions of discrete tectal circuits in the generation of behavior...
  3. pmc Non-SMC condensin I complex proteins control chromosome segregation and survival of proliferating cells in the zebrafish neural retina
    Sabine Seipold
    Max Delbruck Center MDC for Molecular Medicine, Berlin, Germany
    BMC Dev Biol 9:40. 2009
    ..However, due to the lack of appropriate mutants, the function of the condensin I complex during vertebrate development has not been described...
  4. pmc Regulation of neurogenesis by interkinetic nuclear migration through an apical-basal notch gradient
    Filippo Del Bene
    Department of Physiology, Programs in Neuroscience, Genetics, and Developmental Biology, University of California San Francisco, San Francisco, CA 94158 2722, USA
    Cell 134:1055-65. 2008
    ..Our data indicate that the function of INM is to balance the exposure of progenitor nuclei to neurogenic versus proliferative signals...
  5. pmc Filtering of visual information in the tectum by an identified neural circuit
    Filippo Del Bene
    Department of Physiology, University of California, San Francisco, CA 94158, USA
    Science 330:669-73. 2010
    ..Photo-ablation of these cells with KillerRed, or silencing of their synaptic transmission, eliminates the size tuning of deeper layers and impairs the capture of prey...
  6. pmc Forward genetic analysis of visual behavior in zebrafish
    Akira Muto
    Department of Physiology, Programs in Neuroscience, Genetics, and Developmental Biology, Center for Human Genetics, University of California, San Francisco, California, United States of America
    PLoS Genet 1:e66. 2005
    ..This collection of zebrafish behavioral mutants provides a novel resource for the study of normal vision and its genetic disorders...
  7. pmc A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos
    Suk Won Jin
    Department of Biochemistry and Biophysics, Genetics and Human Genetics, and Cardiovascular Research Institute, University of California San Francisco, CA 94158, USA
    Dev Biol 307:29-42. 2007
    ..The analysis of the newly defined loci should lead to a greater understanding of vascular development and possibly provide new drug targets to treat the numerous pathologies associated with dysregulated blood vessel growth...
  8. ncbi request reprint A GFP-based genetic screen reveals mutations that disrupt the architecture of the zebrafish retinotectal projection
    Tong Xiao
    Department of Physiology, University of California, San Francisco, Programs in Neuroscience, Genetics, Human Genetics, and Developmental Biology, 1550 4th Street, San Francisco, CA 94158 2722, USA
    Development 132:2955-67. 2005
    ..The mutated genes are predicted to encode molecules essential for building the intricate neural architecture of the visual system...
  9. pmc Genetic and physiologic dissection of the vertebrate cardiac conduction system
    Neil C Chi
    Department of Biochemistry and Biophysics and Programs in Developmental Biology, Genetics, and Human Genetics, University of California San Francisco, San Francisco, California, United States of America
    PLoS Biol 6:e109. 2008
    ....
  10. pmc Optogenetic localization and genetic perturbation of saccade-generating neurons in zebrafish
    Peter J Schoonheim
    Department of Physiology, Programs in Neuroscience, Genetics and Developmental Biology, University of California, San Francisco, San Francisco, California 94158 2324, USA
    J Neurosci 30:7111-20. 2010
    ....
  11. pmc Topoisomerase IIbeta is required for lamina-specific targeting of retinal ganglion cell axons and dendrites
    Linda M Nevin
    Department of Physiology, University of California, San Francisco, 1550 4th Street, San Francisco, CA 94158 2722, USA
    Development 138:2457-65. 2011
    ..The noto mutant provides the first example of the importance of an epigenetic regulator, Top2b, in the intricate series of events that lead to a properly wired visual system...
  12. doi request reprint Optogenetic control of cardiac function
    Aristides B Arrenberg
    Department of Physiology, University of California, San Francisco, CA 94158, USA
    Science 330:971-4. 2010
    ..Our studies combine optogenetics and light-sheet microscopy to reveal the emergence of organ function during development...
  13. pmc An essential role for Radar (Gdf6a) in inducing dorsal fate in the zebrafish retina
    Nathan J Gosse
    Department of Physiology, Program in Developmental Biology, Genetics, University of California, 1550 Fourth Street, San Francisco, CA 94158 2722, USA
    Proc Natl Acad Sci U S A 106:2236-41. 2009
    ..We conclude that Radar is near the top of a signaling cascade that establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map...
  14. pmc Vesicular glutamate transport at a central synapse limits the acuity of visual perception in zebrafish
    Matthew C Smear
    University of California, San Francisco, Department of Physiology, Program in Neuroscience, 1550 4th Street, San Francisco, CA 94143, USA
    Neuron 53:65-77. 2007
    ..Our studies successfully link the disruption of a synaptic protein to complex changes in neural circuitry and behavior...
  15. ncbi request reprint Targeting neural circuitry in zebrafish using GAL4 enhancer trapping
    Ethan K Scott
    Department of Physiology, University of California, San Francisco, California 94158, USA
    Nat Methods 4:323-6. 2007
    ..Through targeted photoconversion of UAS-driven Kaede and variegated expression of UAS-driven GFP in single cells, we begin to characterize the cellular components of labeled circuits...
  16. pmc Assembly of lamina-specific neuronal connections by slit bound to type IV collagen
    Tong Xiao
    Programs in Neuroscience, Department of Physiology, University of California, San Francisco, 1550 Fourth Street, San Francisco, CA 94158 2722, USA
    Cell 146:164-76. 2011
    ..We propose that Slit1 signaling, perhaps in the form of a superficial-to-deep gradient, presents laminar positional cues to ingrowing retinal axons...
  17. pmc Optical control of zebrafish behavior with halorhodopsin
    Aristides B Arrenberg
    Department of Physiology, Program in Neuroscience, University of California, San Francisco, 1550 4th Street, San Francisco, CA 94158 2324, USA
    Proc Natl Acad Sci U S A 106:17968-73. 2009
    ..Together this "optogenetic toolkit" allows loss-of-function and gain-of-function analyses of neural circuitry at high spatial and temporal resolution in a behaving vertebrate...
  18. ncbi request reprint The g protein-coupled receptor agtrl1b regulates early development of myocardial progenitors
    Ian C Scott
    Department of Biochemistry and Biophysics, Programs in Developmental Biology, Genetics and Human Genetics, and Cardiovascular Research Institute, University of California, San Francisco, 1550 4th Street, San Francisco, CA 94158, USA
    Dev Cell 12:403-13. 2007
    ..These results support a model in which agtrl1b regulates the migration of cells fated to form myocardial progenitors...
  19. ncbi request reprint Lamina-specific axonal projections in the zebrafish tectum require the type IV collagen Dragnet
    Tong Xiao
    Department of Physiology, Programs in Neuroscience, Genetics, and Developmental Biology, University of California, San Francisco, California 94158 2324, USA
    Nat Neurosci 10:1529-37. 2007
    ..Our results show that the collagen IV sheet anchors secreted factors at the surface of the tectum, which serve as guidance cues for retinal axons...
  20. ncbi request reprint Staggered cell-intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina
    Jeremy N Kay
    Department of Physiology, University of California, 1550 Fourth Street, San Francisco, CA 94158, USA
    Development 132:2573-85. 2005
    ....
  21. pmc ALDH1A3 loss of function causes bilateral anophthalmia/microphthalmia and hypoplasia of the optic nerve and optic chiasm
    Mani Yahyavi
    Division of Genetics, Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143 0748, USA
    Hum Mol Genet 22:3250-8. 2013
    ..We conclude that ALDH1A3 loss of function causes anophthalmia and aberrant eye development in humans and in animal model systems. ..
  22. pmc Glucocorticoid receptor activity regulates light adaptation in the zebrafish retina
    Akira Muto
    Department of Physiology, University of California at San Francisco San Francisco, CA, USA
    Front Neural Circuits 7:145. 2013
    ..We suggest that GR controls a gene network required for visual adaptation in the zebrafish retina and potentially integrates neuroendocrine and sensory responses to environmental changes...
  23. pmc Neuroendocrine transcriptional programs adapt dynamically to the supply and demand for neuropeptides as revealed in NSF mutant zebrafish
    Deborah M Kurrasch
    Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA
    Neural Dev 4:22. 2009
    ..The conserved function and spatial expression of hypothalamic peptides in vertebrates prompted us to search for critical neuroendocrine genes in newly hatched zebrafish larvae...
  24. pmc Hardwiring of fine synaptic layers in the zebrafish visual pathway
    Linda M Nevin
    Department of Physiology, University of California, San Francisco, CA 94158, USA
    Neural Dev 3:36. 2008
    ..Here we investigated two stratified areas of the zebrafish visual pathway, the inner plexiform layer (IPL) of the retina and the neuropil of the optic tectum, and determined if activity is required for their organization...
  25. pmc Emergence of patterned activity in the developing zebrafish spinal cord
    Erica Warp
    Helen Wills Neuroscience Graduate Program, University of California, Berkeley, Berkeley, CA 94720, USA
    Curr Biol 22:93-102. 2012
    ..It is also unknown whether early, uncorrelated activity is necessary for the formation of the coordinated CPG...
  26. pmc Retinotopic order in the absence of axon competition
    Nathan J Gosse
    Program in Developmental Biology, University of California, San Francisco, Department of Physiology, 1550 Fourth Street, San Francisco, California 94158 2324, USA
    Nature 452:892-5. 2008
    ..We conclude that dense innervation is not required for targeting of retinal axons within the zebrafish tectum but serves to restrict arbor size and shape...
  27. pmc A male with unilateral microphthalmia reveals a role for TMX3 in eye development
    Ryan Chao
    Division of Genetics, Department of Pediatrics, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 5:e10565. 2010
    ..Future experiments to determine if other thioredoxins are important in eye morphogenesis and to clarify the mechanism of function of TMX3 in eye development are warranted...
  28. pmc Entrained rhythmic activities of neuronal ensembles as perceptual memory of time interval
    German Sumbre
    Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720, USA
    Nature 456:102-6. 2008
    ..Thus, rhythmic activities among specific neuronal ensembles may act as an adjustable 'metronome' for time intervals in the order of seconds, and serve as a mechanism for the short-term perceptual memory of rhythmic sensory experience...
  29. pmc Focusing on optic tectum circuitry through the lens of genetics
    Linda M Nevin
    Department of Physiology, University of California, San Francisco, 1550 4th Street, San Francisco, CA 94158 23241, USA
    BMC Biol 8:126. 2010
    ..Here, we discuss recent advances and emerging experimental approaches for studying tectal circuits as models for visual processing and sensorimotor transformation by the vertebrate brain...
  30. ncbi request reprint The anaphase-promoting complex is required in both dividing and quiescent cells during zebrafish development
    Ann M Wehman
    Programs in Genetics and Developmental Biology, University of California San Francisco, 1550 4th Street, San Francisco, CA 94158 2722, USA
    Dev Biol 303:144-56. 2007
    ....
  31. pmc SINs and SOMs: neural microcircuits for size tuning in the zebrafish and mouse visual pathway
    Alison J Barker
    Department Genes Circuits Behavior, Max Planck Institute of Neurobiology Martinsried, Germany Neuroscience Graduate Program, University of California San Francisc San Francisco, CA, USA
    Front Neural Circuits 7:89. 2013
    ..Both results provide exciting evidence for mechanisms of size filtering in visual circuits. Here we review the roles of the SINs and the SOMs and speculate on the similarity of such spatial filters across species...
  32. ncbi request reprint Of lasers, mutants, and see-through brains: functional neuroanatomy in zebrafish
    Ethan Gahtan
    UCSF Department of Physiology, Program in Neuroscience, 513 Parnassus Avenue, Room S 762, San Francisco, California 94143 0444, USA
    J Neurobiol 59:147-61. 2004
    ..Although still in an embryonic stage, the neuroanatomy of behaviors in zebrafish has a bright future...
  33. ncbi request reprint Channeling of red and green cone inputs to the zebrafish optomotor response
    Michael B Orger
    Department of Physiology, Program in Neuroscience, University of California San Francisco, 94143, USA
    Vis Neurosci 22:275-81. 2005
    ..Therefore, natural stimuli, which contain a mixture of spatial frequencies, are likely to be visible regardless of their chromatic composition...
  34. ncbi request reprint Genetic dissection of the zebrafish retinal stem-cell compartment
    Ann M Wehman
    Program in Genetics, University of California, San Francisco, 1550 4th Street, San Francisco, CA 94158, USA
    Dev Biol 281:53-65. 2005
    ..Our study suggests that embryonic and post-embryonic stem cells utilize separable genetic programs in the zebrafish retina...
  35. ncbi request reprint Behavioral screening assays in zebrafish
    Michael B Orger
    Program in Neuroscience, Department of Physiology, University of California, San Francisco, San Francisco, California 94143, USA
    Methods Cell Biol 77:53-68. 2004
  36. ncbi request reprint Out-foxing fate; molecular switches create neuronal diversity in the retina
    Jeremy N Kay
    Department of Physiology and Programs in Neuroscience, Genetics, and Developmental Biology, University of California, San Francisco, 1550 Fourth Street, San Francisco, CA 94158, USA
    Neuron 43:759-60. 2004
    ..Two reports in this issue of Neuron reveal two transcription factors (Foxn4 and Bhlhb4) that contribute to the development of this remarkable cellular diversity...
  37. ncbi request reprint Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development
    Dimitris Beis
    Department of Biochemistry and Biophysics and Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94143, USA
    Development 132:4193-204. 2005
    ..This collection of mutants provides a unique set of tools to further our understanding of the genetic basis of cell behavior and differentiation during AV valve development...
  38. ncbi request reprint Remote control of neuronal activity with a light-gated glutamate receptor
    Stephanie Szobota
    Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA
    Neuron 54:535-45. 2007
    ..Our studies show that LiGluR provides robust control over neuronal activity, enabling the dissection and manipulation of neural circuitry in vivo...
  39. pmc A zebrafish model of glucocorticoid resistance shows serotonergic modulation of the stress response
    Brian B Griffiths
    Department of Psychology, Humboldt State University Arcata, CA, USA
    Front Behav Neurosci 6:68. 2012
    ....
  40. ncbi request reprint Retinal network adaptation to bright light requires tyrosinase
    Patrick S Page-McCaw
    University of California, San Francisco, Department of Physiology, Program in Neuroscience, 513 Parnassus Ave, San Francisco, California 94143 0444, USA
    Nat Neurosci 7:1329-36. 2004
    ..We propose that retinal pigment epithelium (which normally expresses tyrosinase) secretes a modulatory factor, possibly L-DOPA, which regulates light adaptation in the retinal circuitry...
  41. ncbi request reprint Transient requirement for ganglion cells during assembly of retinal synaptic layers
    Jeremy N Kay
    Program in Neuroscience and Department of Physiology, University of California, San Francisco, 513 Parnassus Avenue Box 0444, San Francisco, CA 94143, USA
    Development 131:1331-42. 2004
    ..Furthermore, our results suggest that amacrines may guide IPL sublamination by providing stratification cues for other cell types...
  42. pmc Characterization of genetically targeted neuron types in the zebrafish optic tectum
    Estuardo Robles
    Department of Physiology, University of California San Francisco San Francisco, CA, USA
    Front Neural Circuits 5:1. 2011
    ..These observations establish a framework for studying the morphological and functional differentiation of neural circuits in the zebrafish visual system...
  43. ncbi request reprint Visuomotor behaviors in larval zebrafish after GFP-guided laser ablation of the optic tectum
    Tobias Roeser
    Department of Physiology and Programs in Neuroscience, Genetics, Developmental Biology, and Human Genetics, University of California at San Francisco, San Francisco, California 94143 0444, USA
    J Neurosci 23:3726-34. 2003
    ....
  44. pmc Loss of eyes in zebrafish caused by mutation of chokh/rx3
    Felix Loosli
    Developmental Biology Programme, European Molecular Biology Laboratory, Meyerhofstrasse 1, PO Box 10 2209, 69012 Heidelberg, Germany
    EMBO Rep 4:894-9. 2003
    ..Thus, these mutations in orthologous genes allow us to study the evolution of vertebrate eye development at the molecular level...
  45. ncbi request reprint Regulation of axon growth in vivo by activity-based competition
    Jackie Yuanyuan Hua
    Department of Molecular and Cellular Physiology, Stanford University, Stanford, California 94305, USA
    Nature 434:1022-6. 2005
    ..These results therefore identify a new form of activity-based competition rule that might be a key regulator of axon growth and branch initiation...
  46. ncbi request reprint Visual prey capture in larval zebrafish is controlled by identified reticulospinal neurons downstream of the tectum
    Ethan Gahtan
    Department of Psychology, University of Massachusetts, Amherst, Massachusetts 01003, USA
    J Neurosci 25:9294-303. 2005
    ..These results suggest that MeLc and MeLr function in series with the tectum, as part of a circuit that coordinates prey capture movements...
  47. pmc Transactivation from Gal4-VP16 transgenic insertions for tissue-specific cell labeling and ablation in zebrafish
    Jon M Davison
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Dev Biol 304:811-24. 2007
    ....
  48. pmc In vivo imaging reveals dendritic targeting of laminated afferents by zebrafish retinal ganglion cells
    Jeff S Mumm
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 52:609-21. 2006
    ..Dendritic targeting of prepatterned afferents may thus be a novel mechanism for establishing proper synaptic connectivity...
  49. ncbi request reprint Slit1a inhibits retinal ganglion cell arborization and synaptogenesis via Robo2-dependent and -independent pathways
    Douglas S Campbell
    Department of Neurobiology and Anatomy, University of Utah Medical Center, Salt Lake City, UT 84132, USA
    Neuron 55:231-45. 2007
    ..Unlike previous PNS studies showing that Slits promote branching, our results show that Slits inhibit arborization and synaptogenesis in the CNS...
  50. ncbi request reprint Two zebrafish mutants, ebony and ivory, uncover benefits of neighborhood on photoreceptor survival
    Paul Goldsmith
    Department of Anatomy, University of Cambridge, Downing Site, Cambridge, CB2 3DY, United Kingdom
    J Neurobiol 57:235-45. 2003
    ..The rescue at a distance is in keeping with a putative diffusible survival factor. We propose a density-dependent nonautonomous neighborhood effect to explain these findings...
  51. pmc In vivo validation of a computationally predicted conserved Ath5 target gene set
    Filippo Del Bene
    Developmental Biology Programme, European Molecular Biology Laboratory, Heidelberg, Heidelberg, Germany
    PLoS Genet 3:1661-71. 2007
    ..Thus, our procedure, applied to whole genomes, is a fast and predictive tool to in silico filter the target genes of a given transcription factor with defined binding site...

Research Grants21

  1. Genetic Analysis of Visual-System Development
    Herwig Baier; Fiscal Year: 2006
    ..Health-relatedness. This approach may lead a way to isolating genes involved in diseases of the human retina, such as glaucoma and optic-nerve hypoplasia, for which there are currently no cures ..
  2. Genetic Analysis of Visual-System Development
    Herwig Baier; Fiscal Year: 2005
    ..Health-relatedness. This approach may lead a way to isolating genes involved in diseases of the human retina, such as glaucoma and optic-nerve hypoplasia, for which there are currently no cures ..
  3. Genetic Tools for the Analysis of Nervous Systems Functions
    Herwig Baier; Fiscal Year: 2009
    ..The reagents and techniques developed under this proposal will advance biomedical research throughout the zebrafish community. ..
  4. Genetic Analysis of Visual-System Development
    Herwig Baier; Fiscal Year: 2003
    ..Health-relatedness. This approach may lead a way to isolating genes involved in diseases of the human retina, such as glaucoma and optic-nerve hypoplasia, for which there are currently no cures ..
  5. LARGE SCALE GENETIC APPROACH TO ZEBRAFISH VISUAL SYSTEM
    Herwig Baier; Fiscal Year: 2002
    ....
  6. Genetic approach to the assembly of parallel circuits in the visual system
    Herwig Baier; Fiscal Year: 2010
    ..This study proposes to identify the molecules that are important for this process during development and growth of the vertebrate organism, thus. ..
  7. Genetic approach to the assembly of parallel circuits in the visual system
    Herwig Baier; Fiscal Year: 2009
    ..This study proposes to identify the molecules that are important for this process during development and growth of the vertebrate organism, thus. ..
  8. Genetic Tools for the Analysis of Nervous Systems Functions
    Herwig Baier; Fiscal Year: 2009
    ..The reagents and techniques developed under this proposal will advance biomedical research throughout the zebrafish community. ..
  9. LARGE SCALE GENETIC APPROACH TO ZEBRAFISH VISUAL SYSTEM
    Herwig Baier; Fiscal Year: 2000
    ....
  10. Genetic Tools for the Analysis of Nervous Systems Functions
    Herwig Baier; Fiscal Year: 2007
    ..The reagents and techniques developed under this proposal will advance biomedical research throughout the zebrafish community. ..
  11. Genetic Analysis of Retinotectal Connectivity
    Herwig Baier; Fiscal Year: 2007
    ..Human and fish visual systems are very similar. Our approach, therefore, may lead a way to understanding the molecular basis of inherited and acquired afflictions of the visual pathway in human patients. ..
  12. Genetic approach to the assembly of parallel circuits in the visual system
    Herwig Baier; Fiscal Year: 2007
    ..This study proposes to identify the molecules that are important for this process during development and growth of the vertebrate organism, thus. ..
  13. Genetic Analysis of Retinotectal Connectivity
    Herwig Baier; Fiscal Year: 2006
    ..Human and fish visual systems are very similar. Our approach, therefore, may lead a way to understanding the molecular basis of inherited and acquired afflictions of the visual pathway in human patients. ..
  14. Genetic Analysis of Retinotectal Connectivity
    Herwig Baier; Fiscal Year: 2005
    ..Human and fish visual systems are very similar. Our approach, therefore, may lead a way to understanding the molecular basis of inherited and acquired afflictions of the visual pathway in human patients. ..
  15. Genetic Analysis of Visual-System Development
    Herwig Baier; Fiscal Year: 2004
    ..Health-relatedness. This approach may lead a way to isolating genes involved in diseases of the human retina, such as glaucoma and optic-nerve hypoplasia, for which there are currently no cures ..
  16. LARGE SCALE GENETIC APPROACH TO VISUAL SYSTEM
    Herwig Baier; Fiscal Year: 2003
    ....
  17. LARGE SCALE GENETIC APPROACH TO ZEBRAFISH VISUAL SYSTEM
    Herwig Baier; Fiscal Year: 2001
    ....
  18. Genetic Tools for the Analysis of Nervous Systems Functions
    Herwig Baier; Fiscal Year: 2010
    ..The reagents and techniques developed under this proposal will advance biomedical research throughout the zebrafish community. ..