J W Baddley

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. doi request reprint Antifungal therapy and length of hospitalization in transplant patients with invasive aspergillosis
    John W Baddley
    Department of Medicine, University of Alabama at Birmingham and Birmingham VA Medical Center, Birmingham, Alabama 35294 0006, USA
    Med Mycol 51:128-35. 2013
  2. pmc Aspergillosis in Intensive Care Unit (ICU) patients: epidemiology and economic outcomes
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, 1900 University Boulevard, 229 Tinsley Harrison Tower, Birmingham, AL 35294 0006, USA
    BMC Infect Dis 13:29. 2013
  3. pmc The use, safety, and effectiveness of herpes zoster vaccination in individuals with inflammatory and autoimmune diseases: a longitudinal observational study
    Jie Zhang
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 1665 University Blvd, Birmingham, AL 35294, USA
    Arthritis Res Ther 13:R174. 2011
  4. pmc Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis
    Jeffrey R Curtis
    Department of Medicine, University of Alabama, 510 20th Street South, FOT 805D, Birmingham, AL 35294, USA
    Arthritis Res Ther 13:R155. 2011
  5. doi request reprint Pulmonary cryptococcosis in patients without HIV infection: factors associated with disseminated disease
    J W Baddley
    Division of Infectious Diseases and International Health, Department of Medicine, University of Alabama at Birmingham, 1900 University Boulevard, 229 Tinsley Harrison Tower, Birmingham, AL 35294 0006, USA
    Eur J Clin Microbiol Infect Dis 27:937-43. 2008
  6. pmc Association of fluconazole pharmacodynamics with mortality in patients with candidemia
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, AL 35294 0006, USA
    Antimicrob Agents Chemother 52:3022-8. 2008
  7. doi request reprint Histoplasmosis in HIV-infected patients in a southern regional medical center: poor prognosis in the era of highly active antiretroviral therapy
    John W Baddley
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 0006, USA
    Diagn Microbiol Infect Dis 62:151-6. 2008
  8. pmc Patterns of susceptibility of Aspergillus isolates recovered from patients enrolled in the Transplant-Associated Infection Surveillance Network
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL 35294 0006, USA
    J Clin Microbiol 47:3271-5. 2009
  9. pmc Factors associated with mortality in transplant patients with invasive aspergillosis
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, AL 35294 0006, USA
    Clin Infect Dis 50:1559-67. 2010
  10. doi request reprint Clinical risk factors for invasive aspergillosis
    John W Baddley
    University of Alabama at Birmingham, and Birmingham Veterans Affairs Medical Center, 1900 University Boulevard, Birmingham, AL 35294, USA
    Med Mycol 49:S7-S12. 2011

Research Grants

Detail Information

Publications37

  1. doi request reprint Antifungal therapy and length of hospitalization in transplant patients with invasive aspergillosis
    John W Baddley
    Department of Medicine, University of Alabama at Birmingham and Birmingham VA Medical Center, Birmingham, Alabama 35294 0006, USA
    Med Mycol 51:128-35. 2013
    ..Initial voriconazole use was associated with decreased LOS. Further investigation on impact of antifungal therapy on economic outcomes is needed...
  2. pmc Aspergillosis in Intensive Care Unit (ICU) patients: epidemiology and economic outcomes
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, 1900 University Boulevard, 229 Tinsley Harrison Tower, Birmingham, AL 35294 0006, USA
    BMC Infect Dis 13:29. 2013
    ..The aim of this study was to examine epidemiology and economic outcomes (length of stay, hospital costs) among ICU patients with IA who lack traditional risk factors for IA, such as cancer, transplants, neutropenia or HIV infection...
  3. pmc The use, safety, and effectiveness of herpes zoster vaccination in individuals with inflammatory and autoimmune diseases: a longitudinal observational study
    Jie Zhang
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 1665 University Blvd, Birmingham, AL 35294, USA
    Arthritis Res Ther 13:R174. 2011
    ....
  4. pmc Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis
    Jeffrey R Curtis
    Department of Medicine, University of Alabama, 510 20th Street South, FOT 805D, Birmingham, AL 35294, USA
    Arthritis Res Ther 13:R155. 2011
    ..We created and tested a claims-based algorithm to serve as a proxy for the clinical effectiveness of RA medications...
  5. doi request reprint Pulmonary cryptococcosis in patients without HIV infection: factors associated with disseminated disease
    J W Baddley
    Division of Infectious Diseases and International Health, Department of Medicine, University of Alabama at Birmingham, 1900 University Boulevard, 229 Tinsley Harrison Tower, Birmingham, AL 35294 0006, USA
    Eur J Clin Microbiol Infect Dis 27:937-43. 2008
    ..These findings may be helpful in the evaluation of HIV-negative patients with pulmonary cryptococcosis with regard to the need for lumbar puncture or to search for disseminated disease...
  6. pmc Association of fluconazole pharmacodynamics with mortality in patients with candidemia
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, AL 35294 0006, USA
    Antimicrob Agents Chemother 52:3022-8. 2008
    ..In addition, similar MICs were obtained using a 24- or 48-h MIC endpoint determination, thus providing the opportunity to assess earlier the impact of isolate susceptibility on therapy...
  7. doi request reprint Histoplasmosis in HIV-infected patients in a southern regional medical center: poor prognosis in the era of highly active antiretroviral therapy
    John W Baddley
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 0006, USA
    Diagn Microbiol Infect Dis 62:151-6. 2008
    ..8-0.98; P=0.02) were independent predictors of poor prognosis. Histoplasmosis in HIV patients is associated with poor outcomes. Identification of prognostic factors may be helpful in identifying patients who require more aggressive care...
  8. pmc Patterns of susceptibility of Aspergillus isolates recovered from patients enrolled in the Transplant-Associated Infection Surveillance Network
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL 35294 0006, USA
    J Clin Microbiol 47:3271-5. 2009
    ..61; P = 0.065). Significant relationships of in vitro MIC to all-cause mortality at 6 and 12 weeks for VOR or AMB were not found...
  9. pmc Factors associated with mortality in transplant patients with invasive aspergillosis
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, AL 35294 0006, USA
    Clin Infect Dis 50:1559-67. 2010
    ..The purpose of this study was to evaluate factors associated with mortality in transplant patients with IA...
  10. doi request reprint Clinical risk factors for invasive aspergillosis
    John W Baddley
    University of Alabama at Birmingham, and Birmingham Veterans Affairs Medical Center, 1900 University Boulevard, Birmingham, AL 35294, USA
    Med Mycol 49:S7-S12. 2011
    ..Identification of clinical risk factors for IA may help in determining which patients require risk modification and other prevention measures...
  11. doi request reprint Transmission of Cryptococcus neoformans by Organ Transplantation
    John W Baddley
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Clin Infect Dis 52:e94-8. 2011
    ..This article describes transmission of Cryptococcus neoformans by solid organ transplantation...
  12. pmc Geographic distribution of endemic fungal infections among older persons, United States
    John W Baddley
    University of Alabama at Birmingham, Birmingham, AL35294 0006, USA
    Emerg Infect Dis 17:1664-9. 2011
    ..1%) cases, there was no patient exposure to a traditional disease-endemic area. Knowledge of areas where endemic mycosis incidence is increased may affect diagnostic or prevention measures for older adults at risk...
  13. pmc Candida infective endocarditis
    J W Baddley
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 0006, USA
    Eur J Clin Microbiol Infect Dis 27:519-29. 2008
    ..Indications for surgical intervention are different and mortality is increased. Newer antifungal treatment options are increasingly used. Large, multi-center studies are needed to help better define Candida IE...
  14. ncbi request reprint Trends in frequency and susceptibilities of Candida glabrata bloodstream isolates at a university hospital
    J W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Diagn Microbiol Infect Dis 39:199-201. 2001
    ..The frequency of C. glabrata isolates among all blood culture isolates of Candida spp. causing bloodstream infection remained stable during the study period and ranged from 18-31%...
  15. ncbi request reprint Utility of real-time antifungal susceptibility testing for fluconazole in the treatment of candidemia
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA
    Diagn Microbiol Infect Dis 50:119-24. 2004
    ..Routine susceptibility testing as an adjunct to the treatment of candidemia has significant potential and warrants further study...
  16. ncbi request reprint Surgical treatment of multiple skull abscesses associated with coccidioidomycosis
    J W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, 35294 0006, USA
    Mycoses 47:69-71. 2004
    ..Despite prolonged aggressive medical management, these lesions failed to resolve until they were surgically drained...
  17. pmc Epidemiology of Aspergillus terreus at a university hospital
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama 35294 0006, USA
    J Clin Microbiol 41:5525-9. 2003
    ..Further surveillance of A. terreus may better define epidemiology and determine whether this organism is becoming more frequent in relation to other Aspergillus species...
  18. ncbi request reprint Fungal brain abscess in transplant recipients: epidemiologic, microbiologic, and clinical features
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, 35294 0006, USA
    Clin Transplant 16:419-24. 2002
    ..Although fungal brain abscess is an uncommon disease in this population, outcome was poor, suggesting that early recognition of this disease might be helpful...
  19. ncbi request reprint Invasive mold infections in allogeneic bone marrow transplant recipients
    J W Baddley
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 0006, USA
    Clin Infect Dis 32:1319-24. 2001
    ..These observations suggest that early identification of high-risk patients and better approaches to prevention should be explored, to reduce incidence and severity of disease in this population...
  20. doi request reprint Pneumocystis pneumonia in hospitalized patients: a detailed examination of symptoms, management, and outcomes in human immunodeficiency virus (HIV)-infected and HIV-uninfected persons
    J A McKinnell
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Transpl Infect Dis 14:510-8. 2012
    ..We postulated that prevention and inpatient management of HIV-PCP differed from NH-PCP...
  21. pmc Microascus cinereus (Anamorph scopulariopsis) brain abscess in a bone marrow transplant recipient
    J W Baddley
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Clin Microbiol 38:395-7. 2000
    ..The patient responded well to treatment by amphotericin B lipid complex, itraconazole, and a craniotomy but later died from secondary complications caused by graft-versus-host disease...
  22. doi request reprint Dissemination of community-associated methicillin-resistant Staphylococcus aureus in a tertiary care hospital
    Mukesh Patel
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, 35294 0006, USA
    South Med J 101:40-5. 2008
    ..The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) was investigated at a tertiary care hospital, and relationship was made between the clinical and genetic definitions of community- and healthcare-associated MRSA...
  23. doi request reprint Active surveillance to determine the impact of methicillin-resistant Staphylococcus aureus colonization on patients in intensive care units of a Veterans Affairs Medical Center
    Mukesh Patel
    Birmingham Veterans Affairs Medical Center, Birmingham, Alabama, USA
    Infect Control Hosp Epidemiol 29:503-9. 2008
    ..We sought to describe the impact of MRSA colonization on patients admitted to intensive care units (ICUs) in the Birmingham Veterans Affairs Medical Center (VAMC)...
  24. ncbi request reprint Implantable cardioverter-defibrillator endocarditis secondary to Candida albicans
    L A Brown
    Department of Medicine, University of Alabama at Birmingham, 35294-0006, USA
    Am J Med Sci 322:160-2. 2001
    ..We describe a case of ICD-associated endocarditis caused by Candida albicans that was successfully treated with complete device explantation and prolonged antifungal therapy, and we review the features of ICD-related fungal infections...
  25. ncbi request reprint Initial management of candidemia at an academic medical center: evaluation of the IDSA guidelines
    Mukesh Patel
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL 35294 0006, USA
    Diagn Microbiol Infect Dis 52:29-34. 2005
    ..Further studies should be performed to validate newer guidelines in a clinical setting at other institutions...
  26. doi request reprint Pinpointing prognostic indicators of fungal infections in transplant patients
    John W Baddley
    University of Alabama at Birmingham, Birmingham, AL, USA
    Future Microbiol 4:77-84. 2009
    ..Herein, prognostic indicators for mortality in transplant patients with IFI are reviewed, with a focus on invasive aspergillosis and invasive candidiasis...
  27. doi request reprint Observational study of the epidemiology and outcomes of vancomycin-resistant Enterococcus bacteraemia treated with newer antimicrobial agents
    J A McKinnell
    Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Division of Infectious Diseases, Torrance, CA 90502, USA
    Epidemiol Infect 139:1342-50. 2011
    ..In conclusion, VRE-BSI is a growing problem, associated with significant 30-day mortality. Multiple factors were associated with poor outcomes at our hospital...
  28. doi request reprint Cryptococcal lung disease
    Rhett M Shirley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama 35294 0006, USA
    Curr Opin Pulm Med 15:254-60. 2009
    ..Meningitis is the most common manifestation of cryptococcosis; however, cryptococcal lung disease is probably underdiagnosed, and knowledge of epidemiology, diagnosis, and treatment is necessary...
  29. ncbi request reprint Antifungal combination therapy: clinical potential
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, and Birmingham Veteran s Administration Medical Center, Birmingham, Alabama 35294 0006, USA
    Drugs 65:1461-80. 2005
    ..Ultimately, the goal is to provide the reader with a comprehensive but useful review to this complicated and often confusing therapeutic dilemma...
  30. doi request reprint Fatal Burkholderia gladioli infection misidentified as Empedobacter brevis in a lung transplant recipient with cystic fibrosis
    K D Brizendine
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Transpl Infect Dis 14:E13-8. 2012
    ..gladioli, which include cases of pneumonia, tracheobronchitis, bacteremia, and abscesses, and demonstrate an all-cause 1-year mortality of approximately 23%, often after combined medical and surgical treatment...
  31. pmc Incidence and risk factors for progressive multifocal leukoencephalopathy among patients with selected rheumatic diseases
    A Bharat
    University of Alabama at Birmingham, AL, USA
    Arthritis Care Res (Hoboken) 64:612-5. 2012
    ....
  32. ncbi request reprint Other viral bioweapons: Ebola and Marburg hemorrhagic fever
    Michelle R Salvaggio
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, 1900 University Boulevard, 229 Tinsley Harrison Tower, Birmingham, AL 35294, USA
    Dermatol Clin 22:291-302, vi. 2004
    ..Herein we discuss the Filoviridae, the agents of Ebola and Marburg hemorrhagic fevers...
  33. ncbi request reprint Emerging fungal resistance
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, 1900 University Boulevard, 229 Tinsley Harrison Tower, Birmingham, AL 35294, USA
    Clin Lab Med 24:721-35, vii. 2004
    ..This review focuses on antifungal resistance, with emphasis on emerging resistance patterns and emerging fungi that are intrinsically resistant to antifungal agents...
  34. pmc Phaeoacremonium parasiticum infections confirmed by beta-tubulin sequence analysis of case isolates
    John W Baddley
    Department of Medicine, Division of Infectious Disease, University of Alabama at Birmingham, Birmingham, AL 34294, USA
    J Clin Microbiol 44:2207-11. 2006
    ..parasiticum. The close DNA similarity, corroborated by relevant morphological similarities (e.g., long, thin phialides and tuberculate hyphae bearing warts up to 3 mum high), confirms these two isolates as P. parasiticum...
  35. ncbi request reprint Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America
    L Joseph Wheat
    MiraVista Diagnostics MiraBella Technologies, Indianapolis, IN 46241, USA
    Clin Infect Dis 45:807-25. 2007
    ..In addition, the panel added recommendations for management of histoplasmosis in children for those aspects that differ from aspects in adults...
  36. ncbi request reprint Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt
    Elias J Anaissie
    Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Clin Infect Dis 43:1031-9. 2006
  37. pmc Phase II, randomized, double-blind, multicenter study comparing the safety and pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia
    J John Weems
    Greenville Hospital Sytem University Medical Center, South Carolina, USA
    Antimicrob Agents Chemother 50:2751-5. 2006
    ..Tefibazumab was well tolerated, with a safety profile similar to those of other monoclonal antibodies. Additional trials are warranted to address the dosing range and efficacy of tefibazumab...

Research Grants2

  1. Mortality in Transplant Patients with Aspergillosis
    John Baddley; Fiscal Year: 2007
    ....