Dimitri Azar

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. pmc MT1-MMP modulates bFGF-induced VEGF-A expression in corneal fibroblasts
    Kyu Yeon Han
    Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL 60612, USA
    Protein Pept Lett 19:1334-9. 2012
  2. pmc Wound healing after keratorefractive surgery: review of biological and optical considerations
    Dimitri T Azar
    Department of Ophthalmology and Visual Sciences, University of Illinois College of Medicine at Chicago, Chicago, IL 60612, USA
    Cornea 31:S9-19. 2012
  3. pmc Characterization of the interaction between endostatin short peptide and VEGF receptor 3
    Kyu Yeon Han
    Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, USA
    Protein Pept Lett 19:969-74. 2012
  4. pmc Corneal epithelial MT1-MMP inhibits vascular endothelial cell proliferation and migration
    Dimitri T Azar
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA
    Cornea 29:321-30. 2010
  5. pmc Thin-flap (sub-Bowman keratomileusis) versus thick-flap laser in situ keratomileusis for moderate to high myopia: case-control analysis
    Dimitri T Azar
    Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Cataract Refract Surg 34:2073-8. 2008
  6. pmc Effect of MT1-MMP deficiency and overexpression in corneal keratocytes on vascular endothelial cell migration and proliferation
    Dimitri T Azar
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Curr Eye Res 33:954-62. 2008
  7. doi request reprint Control-matched analysis of laser in situ keratomileusis outcomes in high myopia
    Takashi Kojima
    Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, 1855 West Taylor Street, Chicago, IL 60612, USA
    J Cataract Refract Surg 34:544-50. 2008
  8. pmc MT1-MMP-mediated cleavage of decorin in corneal angiogenesis
    Tatsuya Mimura
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Vasc Res 46:541-50. 2009
  9. pmc Membrane type-1 matrix metalloproteinase potentiates basic fibroblast growth factor-induced corneal neovascularization
    Tatsuya Onguchi
    Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, 1855 West Taylor St, Chicago, IL 60612, USA
    Am J Pathol 174:1564-71. 2009
  10. pmc Neostatin-7 regulates bFGF-induced corneal lymphangiogenesis
    Takashi Kojima
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    FEBS Lett 582:2515-20. 2008

Research Grants

  1. CORE GRANT FOR VISION RESEARCH
    Dimitri Azar; Fiscal Year: 2007
  2. METALLOPROTEINASE EXPRESSION IN CORNEAL WOUNDS
    Dimitri Azar; Fiscal Year: 2007
  3. METALLOPROTEINASE EXPRESSION IN CORNEAL WOUNDS
    Dimitri Azar; Fiscal Year: 2002
  4. METALLOPROTEINASE EXPRESSION IN CORNEAL WOUNDS
    Dimitri T Azar; Fiscal Year: 2010

Collaborators

Detail Information

Publications14

  1. pmc MT1-MMP modulates bFGF-induced VEGF-A expression in corneal fibroblasts
    Kyu Yeon Han
    Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL 60612, USA
    Protein Pept Lett 19:1334-9. 2012
    ..Additionally, we provide new insight into the signaling relating to MT1-MMP, Ras, and ERK in the bFGF-induced VEGF-A expression pathways within the corneal fibroblasts...
  2. pmc Wound healing after keratorefractive surgery: review of biological and optical considerations
    Dimitri T Azar
    Department of Ophthalmology and Visual Sciences, University of Illinois College of Medicine at Chicago, Chicago, IL 60612, USA
    Cornea 31:S9-19. 2012
    ....
  3. pmc Characterization of the interaction between endostatin short peptide and VEGF receptor 3
    Kyu Yeon Han
    Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, USA
    Protein Pept Lett 19:969-74. 2012
    ..78 x 10⁻⁸ M. Characterization of the mechanism of endostatin binding to VEGFR-3 may lead to the development of novel therapies for lymphangiogenesis-related disorders, such as transplant rejection, lymphedema, and cancer metastasis...
  4. pmc Corneal epithelial MT1-MMP inhibits vascular endothelial cell proliferation and migration
    Dimitri T Azar
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA
    Cornea 29:321-30. 2010
    ..To determine the effects of corneal epithelial membrane-type 1 matrix metalloproteinase (MT1-MMP) on vascular endothelial migration and proliferation...
  5. pmc Thin-flap (sub-Bowman keratomileusis) versus thick-flap laser in situ keratomileusis for moderate to high myopia: case-control analysis
    Dimitri T Azar
    Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Cataract Refract Surg 34:2073-8. 2008
    ..To compare the refractive and visual outcomes of sub-Bowman keratomileusis (SBK) and thick-flap laser in situ keratomileusis (LASIK) for moderate to high myopia and evaluate the effect of corneal flap thickness on outcomes...
  6. pmc Effect of MT1-MMP deficiency and overexpression in corneal keratocytes on vascular endothelial cell migration and proliferation
    Dimitri T Azar
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Curr Eye Res 33:954-62. 2008
    ..To determine the effect of keratocyte-derived MT1-MMP on calf pulmonary artery endothelial cell (CPAE) proliferation and migration...
  7. doi request reprint Control-matched analysis of laser in situ keratomileusis outcomes in high myopia
    Takashi Kojima
    Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, 1855 West Taylor Street, Chicago, IL 60612, USA
    J Cataract Refract Surg 34:544-50. 2008
    ..To evaluate the outcomes of laser in situ keratomileusis (LASIK) for high myopia...
  8. pmc MT1-MMP-mediated cleavage of decorin in corneal angiogenesis
    Tatsuya Mimura
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Vasc Res 46:541-50. 2009
    ..Decorin has been shown to have antiangiogenic properties. In this study, we evaluate the involvement of membrane type 1-matrix metalloproteinase (MT1-MMP), a proangiogenic enzyme, in decorin cleavage in the cornea...
  9. pmc Membrane type-1 matrix metalloproteinase potentiates basic fibroblast growth factor-induced corneal neovascularization
    Tatsuya Onguchi
    Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, 1855 West Taylor St, Chicago, IL 60612, USA
    Am J Pathol 174:1564-71. 2009
    ..These results suggest that MT1-MMP potentiates bFGF-induced corneal neovascularization, likely by modulating the bFGF signal transduction pathway...
  10. pmc Neostatin-7 regulates bFGF-induced corneal lymphangiogenesis
    Takashi Kojima
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    FEBS Lett 582:2515-20. 2008
    ..Understanding the mechanism of neostatin-7/collagen XVIII on corneal lymphangiogenesis may provide therapeutic interventions to treat lymphangiogenesis-related disorders, such as lymphedema, transplantation rejection and cancers...
  11. ncbi request reprint Comparison of EphA receptor tyrosine kinases and ephrinA ligand expression to EphB-ephrinB in vascularized corneas
    Takashi Kojima
    Department of Ophthalmology and Visual Sciences, University of Illinois, Chicago, IL 60612, USA
    Cornea 26:569-78. 2007
    ....
  12. pmc Novel aspects of corneal angiogenic and lymphangiogenic privilege
    David Ellenberg
    Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, 1855W Taylor Street, Chicago, IL, USA
    Prog Retin Eye Res 29:208-48. 2010
    ..Established and potential new therapies for the treatment of corneal neovascularization are also discussed...
  13. doi request reprint Metaanalysis of cataract development after phakic intraocular lens surgery
    Li Ju Chen
    Department of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Cataract Refract Surg 34:1181-200. 2008
    ..Cataract surgical intervention resulted in restoration of visual acuity...
  14. ncbi request reprint Femtosecond-laser arcuate wedge-shaped resection to correct high residual astigmatism after penetrating keratoplasty
    Ramon C Ghanem
    UIC Department of Ophthalmology and Visual Sciences, Chicago, Illinois, USA
    J Cataract Refract Surg 32:1415-9. 2006
    ..5 D of astigmatism. Laser arcuate resection can be an effective alternative to manual wedge resection, allowing easier, more controlled, and more precise excision of tissue in width, length, and depth...

Research Grants13

  1. CORE GRANT FOR VISION RESEARCH
    Dimitri Azar; Fiscal Year: 2007
    ..abstract_text> ..
  2. METALLOPROTEINASE EXPRESSION IN CORNEAL WOUNDS
    Dimitri Azar; Fiscal Year: 2007
    ..The study of MT1-MMP in the cornea may provide valuable information about their possible clinical significance in corneal neovascularization and wound healing. ..
  3. METALLOPROTEINASE EXPRESSION IN CORNEAL WOUNDS
    Dimitri Azar; Fiscal Year: 2002
    ..The study of MMPs and angiostatin in the cornea may provide valuable information about their behavior and possible clinical significance in other tissue. ..
  4. METALLOPROTEINASE EXPRESSION IN CORNEAL WOUNDS
    Dimitri T Azar; Fiscal Year: 2010
    ..Transcriptional up regulation of VEGF and pericellular/transcellular ECM degradation may be two distinct mechanisms by which enzymatically active MT1-MMP promotes angiogenesis. ..