Research Topics
Species | Anthony AzakieSummaryAffiliation: University of California Country: USA Publications
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Publications
Differential responses of the right ventricle to abnormal loading conditions in vivo: Possible pathophysiologic mechanismsAnthony Azakie
Department of Surgery, University of California at San Francisco, San Francisco, Calif Department of Pediatrics, University of California at San Francisco, San Francisco, Calif Electronic address
J Thorac Cardiovasc Surg 145:1335-44. 2013..The purpose of this study is to elucidate possible transcriptional mechanisms of the RV response to pressure versus volume loading in vivo...- Cardiac surgery in low birth weight infants: current outcomesAnthony Azakie
UCSF Benioff Children s Hospital, San Francisco, CA, USA
Interact Cardiovasc Thorac Surg 12:409-13, discussion 414. 2011..Cardiac surgery in LBW infants can be performed with low early and mid-term mortality. LBW infants with chromosomal/genetic anomalies have a higher risk... - Stage II palliation of hypoplastic left heart syndrome without cardiopulmonary bypassAnthony Azakie
UCSF Benioff Children s Hospital, Department of Surgery, University of California, San Francisco, CA 94143, USA
J Thorac Cardiovasc Surg 141:400-6. 2011..The purpose of this study is to determine the early outcomes for stage II palliation of hypoplastic left heart syndrome without cardiopulmonary bypass... - Early outcomes of primary sutureless repair of the pulmonary veinsAnthony Azakie
UCSF Benioff Children s Hospital, Department of Surgery, University of California San Francisco, San Francisco, California 94143, USA
Ann Thorac Surg 92:666-71; discussion 671-2. 2011..The purpose of this study is to determine the early outcomes of primary sutureless repair of pulmonary venoocclusive disease in infants with congenital PV stenosis-hypoplasia or PVs at high risk for progressive stenosis... 
B-type natriuretic peptide levels predict outcomes for children on extracorporeal life support after cardiac surgeryOmar Chikovani
Department of Pediatrics, University of California, San Francisco, Calif 94143 0106, USA
J Thorac Cardiovasc Surg 134:1179-87. 2007..The objective of this study was to investigate potential associations between changes in B-type natriuretic peptide during trials off extracorporeal life support and clinical outcome...- Anomalous coronary artery from the wrong sinus of Valsalva: a physiologic repair strategyNelson Alphonso
Pediatric Heart Center, UCSF Children s Hospital, University of California San Francisco, San Francisco, California 94143, USA
Ann Thorac Surg 83:1472-6. 2007..A coronary artery arising from the wrong aortic sinus, with or without a proximal course between the aorta and the pulmonary artery, may predispose to myocardial ischemia, myocardial infarction, or sudden death... - Early results of the "clamp and sew" Fontan procedure without the use of circulatory supportTakeshi Shinkawa
Division of Pediatric Cardiothoracic Surgery, Department of Surgery, UCSF Benioff Children s Hospital, University of California, San Francisco, California 94143 0117, USA
Ann Thorac Surg 91:1453-9. 2011..The objective of this study is to assess the outcomes of this novel off-pump "clamp and sew" Fontan procedure... - Perioperative B-type natriuretic peptide levels predict outcome after bidirectional cavopulmonary anastomosis and total cavopulmonary connectionJong Hau Hsu
Department of Pediatrics, University of California, San Francisco, Calif 94143, USA
J Thorac Cardiovasc Surg 135:746-53. 2008.... - Size of the right ventricle-to-pulmonary artery conduit impacts mid-term outcome after the Norwood procedure in patients weighing less than 3 kgNaruhito Watanabe
Division of Pediatric Cardiothoracic Surgery, University of California San Francisco, San Francisco, CA, USA
J Thorac Cardiovasc Surg 144:1091-4. 2012..The optimal shunt size for patients who have the Norwood operation with a right ventricle-to-pulmonary artery conduit is controversial. The goal of this study is to compare outcomes of 2 shunt sizes in this population... - Pulmonary valve cusp augmentation with autologous pericardium may improve early outcome for tetralogy of FallotPetros Anagnostopoulos
Division of Pediatric Cardiac Surgery, Pediatric Heart Center, University of California at San Francisco Children s Hospital, San Francisco, Calif, USA
J Thorac Cardiovasc Surg 133:640-7. 2007..We hypothesized that pulmonary valve cusp augmentation with pericardium would decrease pulmonary insufficiency and improve the early outcome for transatrial-transpulmonary tetralogy of Fallot repair requiring transannular patch... - B-type natriuretic peptide levels predict outcome after neonatal cardiac surgeryJong Hau Hsu
Department of Pediatrics, University of California, San Francisco, Calif, USA
J Thorac Cardiovasc Surg 134:939-45. 2007..Therefore, the objective of this study was to determine the predictive value of perioperative B-type natriuretic peptide levels for postoperative outcomes in neonates undergoing cardiac surgery... - Myocardial transcription factors are modulated during pathologic cardiac hypertrophy in vivoAnthony Azakie
University of California, San Francisco, Department of Surgery, San Francisco, Calif 94143, USA
J Thorac Cardiovasc Surg 132:1262-71. 2006..The cardiac troponin T promoter is used as a model gene... - Alterations in cGMP, soluble guanylate cyclase, phosphodiesterase 5, and B-type natriuretic peptide induced by chronic increased pulmonary blood flow in lambsPeter Oishi
Department of Pediatrics, University of California, San Francisco, 505 Parnassus Avenue, Box 0106, San Francisco, CA 94143 0106, USA
Pediatr Pulmonol 42:1057-71. 2007.... - Surgical management of left ventricular outflow tract obstructionPetros V Anagnostopoulos
Department of Surgery, University of California, San Francisco, San Francisco, California, USA
J Card Surg 27:103-11. 2012..Left ventricular outflow tract obstruction (LVOTO) is caused by a spectrum of lesions. This study was performed to determine the outcomes of surgical management of LVOTO... - Prenatal diagnosis of hypoplastic left heart syndrome in current eraAlaina K Kipps
Department of Pediatrics, Division of Cardiology, University of California, San Francisco, Benioff Children s Hospital, USA
Am J Cardiol 108:421-7. 2011..Improved preoperative status was observed in the preDx patients; however, they were born earlier with a lower birthweight. What effect these factors might have on longer term morbidity remains unknown... - The Lecompte maneuver for relief of airway compression in absent pulmonary valve syndromeLars Nolke
Pediatric Heart Center, UCSF Children s Hospital, San Francisco, California, USA
Ann Thorac Surg 81:1802-7. 2006..Surgical mortality rates as high as 16% to 56% have been reported. Here, we describe the surgical results using the Lecompte maneuver, reduction pulmonary arterioplasty, and a valved right ventricle to pulmonary artery (RV-PA) conduit... - Sp3 inhibits Sp1-mediated activation of the cardiac troponin T promoter and is downregulated during pathological cardiac hypertrophy in vivoAnthony Azakie
Department of Surgery, Univ of California, San Francisco, San Francisco, CA 94143, USA
Am J Physiol Heart Circ Physiol 291:H600-11. 2006..This observation is consistent with the in vitro activating function of Sp1 and inhibitory effects of Sp3 on activity of cTnT promoter constructs. Sp factor levels are modulated during the hypertrophic cardiac program in vivo... - Abnormal brain development in newborns with congenital heart diseaseSteven P Miller
Department of Neurology, University of California at San Francisco, San Francisco, USA
N Engl J Med 357:1928-38. 2007..We characterized brain metabolism and microstructure, as measures of brain maturation, in newborns with congenital heart disease before they underwent heart surgery... - Neonatal mitral and tricuspid valve repair for in utero papillary muscle rupturePetros V Anagnostopoulos
Pediatric Heart Center, University of California San Francisco Children s Hospital, San Francisco, California 94143, USA
Ann Thorac Surg 83:1458-62. 2007..We undertook surgical repair of this lesion in the neonatal period and report on our midterm results... - Alterations in plasma B-type natriuretic peptide levels after repair of congenital heart defects: a potential perioperative markerChie-Youn Shih
Department of Pediatrics, University of California, San Francisco, Calif, USA
J Thorac Cardiovasc Surg 131:632-8. 2006..5% and a specificity of 90.2%. CONCLUSIONS: B-type natriuretic peptide determinations might be a useful tool for clinicians caring for infants and children after surgical intervention for congenital heart disease... 
Prenatal diagnosis of atrial restriction in hypoplastic left heart syndrome is associated with decreased 2-year survivalAlexander Lowenthal
Division of Pediatric Cardiology, University of California, San Francisco, San Francisco, CA, USA
Prenat Diagn 32:485-90. 2012..To compare the course of hypoplastic left heart syndrome (HLHS) patients diagnosed prenatally with any degree of atrial restriction with those without evidence of atrial restriction...- Undiagnosed coronary fistula causing low cardiac output syndrome after pediatric heart surgeryNelson Alphonso
Pediatric Heart Center, UCSF Children's Hospital, Division of Pediatric Cardiothoracic Surgery, 513 Parnassus Avenue, Suite S-549, Box 0117, San Francisco, CA 94143-0117, USA
Eur J Cardiothorac Surg 30:397-9. 2006..Following recovery, a fistulous connection between the right coronary artery and main pulmonary artery was demonstrated. Implications and management strategies of unsuspected coronary fistula in pediatric heart surgery are discussed... - Performance of bovine pericardial valves in the pulmonary positionTakeshi Shinkawa
Division of Pediatric Cardiothoracic Surgery, Department of Surgery, University of California, San Francisco, San Francisco, California, USA
Ann Thorac Surg 90:1295-300. 2010..The purpose of this study is to determine the outcome and performance of bovine pericardial valves in the pulmonary position... - Regional and central venous oxygen saturation monitoring following pediatric cardiac surgery: concordance and association with clinical variablesPatrick S McQuillen
Pediatric Heart Center, University of California, San Francisco, USA
Pediatr Crit Care Med 8:154-60. 2007..To compare changes in regional cerebral or flank oxygen saturation measured by near-infrared spectroscopy with changes in central venous oxygen saturation (ScvO2) and to determine clinical variables associated with these changes... - Single-ventricle anatomy predicts delayed microstructural brain developmentViyeka Sethi
Department of Pediatrics and Neurology, University of California, San Francisco Benioff Children s Hospital, San Francisco, California
Pediatr Res 73:661-7. 2013..Echocardiogram variables were not associated with brain metabolic measures.Conclusions:These observations support the hypothesis that obstruction to fetal cerebral blood flow impairs brain microstructural development... - Aortic stenosis in a patient with Hurler's syndrome after bone marrow transplantationNaruhito Watanabe
Department of Surgery, Division of Pediatric Cardiac Surgery, UCSF Benioff Children s Hospital, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
Cardiol Young 21:349-50. 2011..This is the first case report of aortic valve replacement in a patient with Hurler's syndrome treated with bone marrow transplantation that demonstrates progression of the aortic valve disease despite treatment... - Impact of right ventricle to pulmonary artery conduit on outcome of the modified Norwood procedureAnthony Azakie
Department of Surgery, University of Claifornia, San Francisco, CA 94143, USA
Ann Thorac Surg 77:1727-33. 2004..06). CONCLUSIONS: In a relatively high-risk group, neonates having an RV-PA conduit as part of the Norwood procedure have favorable postoperative hemodynamics and a good likelihood of stage I survival... - Rosiglitazone preserves pulmonary vascular function in lambs with increased pulmonary blood flowPeter E Oishi
Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA
Pediatr Res 73:54-61. 2013..Pulmonary vascular function is impaired with increased pulmonary blood flow (PBF). We hypothesized that a peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist would mitigate this effect... - Ross-Konno and endocardial fibroelastosis resection after hybrid stage I palliation in infancy: successful staged left-ventricular rehabilitation and conversion to biventricular circulation after fetal diagnosis of aortic stenosisAnita J Moon-Grady
Pediatric Heart Center, UCSF Benioff Children s Hospital, University of California San Francisco, San Francisco, CA 94143 0117, USA
Pediatr Cardiol 32:211-4. 2011.... - Perioperative antibiotic prophylaxis in paediatric cardiac surgeryNelson Alphonso
Paediatric Heart Center, University of California San Francisco Children's Hospital, San Francisco, California 94143-0117, USA
Cardiol Young 17:12-25. 2007 - Temporal and anatomic risk profile of brain injury with neonatal repair of congenital heart defectsPatrick S McQuillen
Pediatric Heart Center, University of California at San Francisco, San Francisco, CA, USA
Stroke 38:736-41. 2007..The purpose of this study is to define the risk factors for preoperative and postoperative brain injuries and their association with functional cardiac anatomic groups... - Pulmonary interstitial glycogenosis: an unrecognized etiology of persistent pulmonary hypertension of the newborn in congenital heart disease?Monique R Radman
Department of Pediatrics, University of California, 513 Parnassus Avenue, Box 1346, San Francisco, CA, 94143 1346, USA
Pediatr Cardiol 34:1254-7. 2013..Pulmonary interstitial glycogenosis (PIG) arises from a developmental disorder of the pulmonary mesenchyme and presents clinically with reversible neonatal respiratory distress and/or persistent pulmonary hypertension of the newborn (PPHN)... - Invited commentaryAnthony Azakie
Pediatric Heart Center, University of California San Francisco, Department of Surgery, University of California Medical Center, 513 Paranassus Ave, San Francisco, CA94143
Ann Thorac Surg 82:956-7. 2006 - Infection and white matter injury in infants with congenital cardiac diseaseHannah C Glass
Department of Neurology, University of California, San Francisco, United States of America
Cardiol Young 21:562-71. 2011..Infection prevention may have the potential to mitigate long-term neurologic impairment as a consequence of white matter injury, which underscores the importance of attention to infection control for these patients... - Late pulmonary valve implantation after repair of tetralogy of FallotShengli Yin
Division of Pediatric Cardiothoracic Surgery, University of California, San Francisco, CA 94143-0117, USA
Asian Cardiovasc Thorac Ann 13:139-42. 2005..It was concluded that late pulmonary valve implantation after tetralogy of Fallot repair had significant benefits and carried low operative risk... - Immature intrapericardial teratoma in a newborn with elevated alpha-fetoproteinNathalie Roy
Division of Pediatric Cardiothoracic Surgery, Children's Hospital, University of California, San Francisco, San Francisco, California 94143-0118, USA
Ann Thorac Surg 78:e6-8. 2004..The pathologic analysis demonstrated a grade I immature teratoma with foci of hepatoid tissue. The patient had an uneventful postoperative recovery. A review of the literature and pathologic implications are discussed... - Divergent transcriptional enhancer factor-1 regulates the cardiac troponin T promoterAnthony Azakie
Department of Surgery, Univ. of California San Francisco, San Francisco, CA 94143, USA
Am J Physiol Cell Physiol 289:C1522-34. 2005.... - Nitric oxide-endothelin-1 interactions after surgically induced acute increases in pulmonary blood flow in intact lambsPeter Oishi
Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143-0106, USA
Am J Physiol Heart Circ Physiol 290:H1922-32. 2006..Thus NO appears to be important in maintaining a reduction in PVR after acutely increased PBF... - Cerebral oxygen balance is impaired during repair of aortic coarctation in infants and childrenAnthony Azakie
Department of Surgery, University of California, San Francisco, Calif, USA
J Thorac Cardiovasc Surg 130:830-6. 2005..The neurodevelopmental significance of impaired cerebral oxygen balance detected by near-infrared spectroscopy during aortic coarctation repair remains to be elucidated...