Elizabeth H Aylward

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Effects of age on brain volume and head circumference in autism
    E H Aylward
    Department of Radiology, University of Washington School of Medicine, Seattle, WA 98195, USA
    Neurology 59:175-83. 2002
  2. ncbi request reprint Instructional treatment associated with changes in brain activation in children with dyslexia
    E H Aylward
    Department of Radiology, University of Washington, Seattle 98195, USA
    Neurology 61:212-9. 2003
  3. ncbi request reprint Brain activation during face perception: evidence of a developmental change
    E H Aylward
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    J Cogn Neurosci 17:308-19. 2005
  4. ncbi request reprint Caudate volume as an outcome measure in clinical trials for Huntington's disease: a pilot study
    E H Aylward
    Department of Radiology, University of Washington, Box 357115, Seattle, WA 98195, USA
    Brain Res Bull 62:137-41. 2003
  5. ncbi request reprint Onset and rate of striatal atrophy in preclinical Huntington disease
    E H Aylward
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    Neurology 63:66-72. 2004
  6. ncbi request reprint Magnetic resonance imaging outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders
    Susan J Astley
    Department of Epidemiology, University of Washington, Seattle, Washington 98195 7920, USA
    Alcohol Clin Exp Res 33:1671-89. 2009
  7. ncbi request reprint Neuropyschological and behavioral outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders
    Susan J Astley
    Department of Epidemiology, University of Washington, Seattle, USA
    Can J Clin Pharmacol 16:e178-201. 2009
  8. ncbi request reprint Converging evidence for triple word form theory in children with dyslexia
    Todd L Richards
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    Dev Neuropsychol 30:547-89. 2006
  9. pmc Functional magnetic resonance imaging outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders
    Susan J Astley
    Department of Epidemiology, Center on Human Development and Disability, University of Washington, Box 357920, Seattle, WA, 98195 7920, USA
    J Neurodev Disord 1:61-80. 2009
  10. pmc The association between higher order abilities, processing speed, and age are variably mediated by white matter integrity during typical aging
    Paul R Borghesani
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
    Neuropsychologia 51:1435-44. 2013

Detail Information

Publications29

  1. ncbi request reprint Effects of age on brain volume and head circumference in autism
    E H Aylward
    Department of Radiology, University of Washington School of Medicine, Seattle, WA 98195, USA
    Neurology 59:175-83. 2002
    ..To determine whether brain volume, as assessed on MRI scans, differs between individuals with autism and control subjects, and whether such differences are affected by age...
  2. ncbi request reprint Instructional treatment associated with changes in brain activation in children with dyslexia
    E H Aylward
    Department of Radiology, University of Washington, Seattle 98195, USA
    Neurology 61:212-9. 2003
    ..To assess the effects of reading instruction on fMRI brain activation in children with dyslexia...
  3. ncbi request reprint Brain activation during face perception: evidence of a developmental change
    E H Aylward
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    J Cogn Neurosci 17:308-19. 2005
    ..The current results provide biological insight into changes in visual processing of faces that occur with normal development...
  4. ncbi request reprint Caudate volume as an outcome measure in clinical trials for Huntington's disease: a pilot study
    E H Aylward
    Department of Radiology, University of Washington, Box 357115, Seattle, WA 98195, USA
    Brain Res Bull 62:137-41. 2003
    ..Advantages and disadvantages of using MRI caudate volume as an outcome measure are presented. We recommend the adoption of quantitative neuroimaging of caudate volume as an outcome measure in future clinical trials for treatments of HD...
  5. ncbi request reprint Onset and rate of striatal atrophy in preclinical Huntington disease
    E H Aylward
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    Neurology 63:66-72. 2004
    ..Huntington disease (HD) is characterized by striatal atrophy that begins long before the onset of motor symptoms...
  6. ncbi request reprint Magnetic resonance imaging outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders
    Susan J Astley
    Department of Epidemiology, University of Washington, Seattle, Washington 98195 7920, USA
    Alcohol Clin Exp Res 33:1671-89. 2009
    ..Magnetic resonance (MR) technology offers noninvasive methods for in vivo assessment of neuroabnormalities...
  7. ncbi request reprint Neuropyschological and behavioral outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders
    Susan J Astley
    Department of Epidemiology, University of Washington, Seattle, USA
    Can J Clin Pharmacol 16:e178-201. 2009
    ..Clinical and research advancements in the field of fetal alcohol spectrum disorders (FASD) require accurate and valid identification of FASD clinical subgroups...
  8. ncbi request reprint Converging evidence for triple word form theory in children with dyslexia
    Todd L Richards
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    Dev Neuropsychol 30:547-89. 2006
    ..In the 3rd part we discuss the next steps in this programmatic research to move beyond word form alone...
  9. pmc Functional magnetic resonance imaging outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders
    Susan J Astley
    Department of Epidemiology, Center on Human Development and Disability, University of Washington, Box 357920, Seattle, WA, 98195 7920, USA
    J Neurodev Disord 1:61-80. 2009
    ..These results demonstrate the potential research and diagnostic value of this non-invasive MR tool in the field of FASD...
  10. pmc The association between higher order abilities, processing speed, and age are variably mediated by white matter integrity during typical aging
    Paul R Borghesani
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
    Neuropsychologia 51:1435-44. 2013
    ..This illustrates both the anatomical and cognitive selectivity of structure-cognition relationships in the aging brain...
  11. ncbi request reprint Low-frequency signal changes reflect differences in functional connectivity between good readers and dyslexics during continuous phoneme mapping
    Larissa I Stanberry
    Department of Statistics, University of Washington, Seattle, WA 98195, USA
    Magn Reson Imaging 24:217-29. 2006
    ..The methodological, theoretical and clinical significance of the findings for advancing fMRI research and knowledge of dyslexia are discussed...
  12. pmc Midlife memory improvement predicts preservation of hippocampal volume in old age
    Paul R Borghesani
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA
    Neurobiol Aging 33:1148-55. 2012
    ..These findings suggest that improvement in memory in midlife is associated with sparing of hippocampal volume in later life...
  13. ncbi request reprint Reproducibility of proton MR spectroscopic imaging (PEPSI): comparison of dyslexic and normal-reading children and effects of treatment on brain lactate levels during language tasks
    Todd L Richards
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    AJNR Am J Neuroradiol 23:1678-85. 2002
    ....
  14. pmc Neurochemical correlates of caudate atrophy in Huntington's disease
    Jeannie M Padowski
    Department of Radiology, University of Washington School of Medicine, Seattle, Washington, USA Integrated Brain Imaging Center, University of Washington School of Medicine, Seattle, Washington, USA
    Mov Disord 29:327-35. 2014
    ..Observation of decreased Glx suggests that glutamate signaling may be disrupted relatively early in HD, which has important implications for therapeutic approaches...
  15. doi request reprint Longitudinal diffusion tensor imaging in Huntington's Disease
    Kurt E Weaver
    Department of Radiology, University of Washington School of Medicine, Box 357115, Seattle, WA 98195, USA
    Exp Neurol 216:525-9. 2009
    ..These results suggest that longitudinal FA changes may serve as a neuropathological biomarker in HD...
  16. pmc Longitudinal change in regional brain volumes in prodromal Huntington disease
    Elizabeth H Aylward
    Seattle Children s Research Institute, Seattle, Washington, USA
    J Neurol Neurosurg Psychiatry 82:405-10. 2011
    ..This study was designed to examine the potential utility of structural MRI measures as outcome measures for such trials...
  17. pmc Altered medial temporal lobe responses during visuospatial encoding in healthy APOE*4 carriers
    Paul R Borghesani
    Mental Illness Research, Education, and Clinical Center MIRECC, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA
    Neurobiol Aging 29:981-91. 2008
    ..Reduced task-associated MTL activation that does not correlate with either visuospatial perspective or task performance suggests that MTL dysregulation occurs prior to clinical symptoms of dementia in APOE*4 carriers...
  18. ncbi request reprint FMRI investigation of cross-cultural music comprehension
    Steven J Morrison
    School of Music, University of Washington, Seattle, WA 98195 3450, USA
    Neuroimage 20:378-84. 2003
    ..Our findings indicate that listening to culturally different musics may activate similar neural resources but with dissimilar results in recall performance...
  19. ncbi request reprint Change in MRI striatal volumes as a biomarker in preclinical Huntington's disease
    Elizabeth H Aylward
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    Brain Res Bull 72:152-8. 2007
    ..This strategy is essential if efficient and cost-effective clinical trials are to be conducted in the preclinical stage of Huntington's disease...
  20. doi request reprint Magnetic resonance spectroscopy outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders
    Susan J Astley
    Department of Epidemiology, University of Washington, Seattle, WA 98195, USA
    Magn Reson Imaging 27:760-78. 2009
    ..NAA and Cre concentrations did not vary significantly. This study provides further evidence of the vulnerability of the cholinergic system in FASD...
  21. pmc Brain volume and shape in infants with deformational plagiocephaly
    Brent R Collett
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
    Childs Nerv Syst 28:1083-90. 2012
    ..Although the mechanisms accounting for these delays are unknown, one hypothesis focuses on underlying differences in brain development. In this study, we used MRI to examine brain volume and shape in infants with and without DP...
  22. ncbi request reprint MRI volumes of amygdala and hippocampus in non-mentally retarded autistic adolescents and adults
    E H Aylward
    Department of Radiology, University of Washington School of Medicine, Seattle 98195, USA
    Neurology 53:2145-50. 1999
    ..To determine whether volumes of hippocampus and amygdala are abnormal in people with autism...
  23. ncbi request reprint Brain structural abnormalities in young children with autism spectrum disorder
    B F Sparks
    Department of Radiology, University of Washington School of Medicine, Seattle, WA 98105, USA
    Neurology 59:184-92. 2002
    ....
  24. ncbi request reprint Beyond disgust: impaired recognition of negative emotions prior to diagnosis in Huntington's disease
    Shannon A Johnson
    Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA
    Brain 130:1732-44. 2007
    ..In contrast to previous results, we found no evidence of relative impairments in recognizing disgust or fear, and no evidence to support a link between the striatum and disgust recognition...
  25. pmc Verbal episodic memory declines prior to diagnosis in Huntington's disease
    Andrea C Solomon
    Department of Psychological and Brain Sciences, Indiana University, 1101 E 10th Street, Bloomington, IN 47405, USA
    Neuropsychologia 45:1767-76. 2007
    ..These findings indicate that verbal episodic memory is affected in early pre-diagnostic HD and may decline as striatal volumes decrease and individuals approach the motor diagnostic threshold...
  26. ncbi request reprint Regional white matter change in pre-symptomatic Huntington's disease: a diffusion tensor imaging study
    Sarah A J Reading
    Division of Psychiatric Neuroimaging, Department of Psychiatry, The Johns Hopkins University, Phipps 313, Baltimore, MD 21287, USA
    Psychiatry Res 140:55-62. 2005
    ..Our results indicate that, before the onset of manifest HD, there are regional decreases in fractional anisotropy, indicating early white matter disorganization...
  27. ncbi request reprint Anatomical correlates of dyslexia: frontal and cerebellar findings
    Mark A Eckert
    Department of Neuroscience, McKnight Brain Institute of the University of Florida, Gainesville, FL 32610, USA
    Brain 126:482-94. 2003
    ..This study may be the first to show that anomalies in a cerebellar-frontal circuit are associated with rapid automatic naming and the double-deficit subtype of dyslexia...
  28. pmc Effect of long-term corticosteroid use on bone mineral density in children: a prospective longitudinal assessment in the childhood Asthma Management Program (CAMP) study
    H William Kelly
    Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131 0001, USA
    Pediatrics 122:e53-61. 2008
    ..Thus, we assessed the effects of multiple short courses of oral corticosteroids and long-term inhaled corticosteroids on bone mineral accretion over a period of years...
  29. pmc Offering to share: how to put heads together in autism neuroimaging
    Matthew K Belmonte
    Department of Human Development, Cornell University, Martha Van Rensselaer Hall, Ithaca, NY 14853 4401, USA
    J Autism Dev Disord 38:2-13. 2008
    ..A theme in these requirements is the need to preserve creative approaches and risk-taking within individual laboratories at the same time as common standards are provided for these laboratories to build on...