Research Topics
Species | Elizabeth H AylwardSummaryAffiliation: University of Washington Country: USA Publications
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Detail Information
Publications
Brain activation during face perception: evidence of a developmental changeE H Aylward
Department of Radiology, University of Washington, Seattle, WA 98195, USA
J Cogn Neurosci 17:308-19. 2005..The current results provide biological insight into changes in visual processing of faces that occur with normal development...- Onset and rate of striatal atrophy in preclinical Huntington diseaseE H Aylward
Department of Radiology, University of Washington, Seattle, WA 98195, USA
Neurology 63:66-72. 2004..Huntington disease (HD) is characterized by striatal atrophy that begins long before the onset of motor symptoms... - Caudate volume as an outcome measure in clinical trials for Huntington's disease: a pilot studyE H Aylward
Department of Radiology, University of Washington, Box 357115, Seattle, WA 98195, USA
Brain Res Bull 62:137-41. 2003..Advantages and disadvantages of using MRI caudate volume as an outcome measure are presented. We recommend the adoption of quantitative neuroimaging of caudate volume as an outcome measure in future clinical trials for treatments of HD... - Instructional treatment associated with changes in brain activation in children with dyslexiaE H Aylward
Department of Radiology, University of Washington, Seattle 98195, USA
Neurology 61:212-9. 2003..To assess the effects of reading instruction on fMRI brain activation in children with dyslexia... - Effects of age on brain volume and head circumference in autismE H Aylward
Department of Radiology, University of Washington School of Medicine, Seattle, WA 98195, USA
Neurology 59:175-83. 2002..To determine whether brain volume, as assessed on MRI scans, differs between individuals with autism and control subjects, and whether such differences are affected by age... 
Magnetic resonance imaging outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disordersSusan J Astley
Department of Epidemiology, University of Washington, Seattle, Washington 98195 7920, USA
Alcohol Clin Exp Res 33:1671-89. 2009..Magnetic resonance (MR) technology offers noninvasive methods for in vivo assessment of neuroabnormalities...- Neuropyschological and behavioral outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disordersSusan J Astley
Department of Epidemiology, University of Washington, Seattle, USA
Can J Clin Pharmacol 16:e178-201. 2009..Clinical and research advancements in the field of fetal alcohol spectrum disorders (FASD) require accurate and valid identification of FASD clinical subgroups... - Converging evidence for triple word form theory in children with dyslexiaTodd L Richards
Department of Radiology, University of Washington, Seattle, WA 98195, USA
Dev Neuropsychol 30:547-89. 2006..In the 3rd part we discuss the next steps in this programmatic research to move beyond word form alone... 
Functional magnetic resonance imaging outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disordersSusan J Astley
Department of Epidemiology, Center on Human Development and Disability, University of Washington, Box 357920, Seattle, WA, 98195 7920, USA
J Neurodev Disord 1:61-80. 2009..These results demonstrate the potential research and diagnostic value of this non-invasive MR tool in the field of FASD...- Low-frequency signal changes reflect differences in functional connectivity between good readers and dyslexics during continuous phoneme mappingLarissa I Stanberry
Department of Statistics, University of Washington, Seattle, WA 98195, USA
Magn Reson Imaging 24:217-29. 2006..The methodological, theoretical and clinical significance of the findings for advancing fMRI research and knowledge of dyslexia are discussed... - Reproducibility of proton MR spectroscopic imaging (PEPSI): comparison of dyslexic and normal-reading children and effects of treatment on brain lactate levels during language tasksTodd L Richards
Department of Radiology, University of Washington, Seattle, WA 98195, USA
AJNR Am J Neuroradiol 23:1678-85. 2002..However, the treatment effect was due to the morphologic component rather than the phonologic component... - Longitudinal change in regional brain volumes in prodromal Huntington diseaseElizabeth H Aylward
Seattle Children s Research Institute, Seattle, Washington, USA
J Neurol Neurosurg Psychiatry 82:405-10. 2011..This study was designed to examine the potential utility of structural MRI measures as outcome measures for such trials... - Longitudinal diffusion tensor imaging in Huntington's DiseaseKurt E Weaver
Department of Radiology, University of Washington School of Medicine, Box 357115, Seattle, WA 98195, USA
Exp Neurol 216:525-9. 2009..These results suggest that longitudinal FA changes may serve as a neuropathological biomarker in HD... - FMRI investigation of cross-cultural music comprehensionSteven J Morrison
School of Music, University of Washington, Seattle, WA 98195 3450, USA
Neuroimage 20:378-84. 2003..Our findings indicate that listening to culturally different musics may activate similar neural resources but with dissimilar results in recall performance... - Altered medial temporal lobe responses during visuospatial encoding in healthy APOE*4 carriersPaul R Borghesani
Mental Illness Research, Education, and Clinical Center MIRECC, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA
Neurobiol Aging 29:981-91. 2008..Reduced task-associated MTL activation that does not correlate with either visuospatial perspective or task performance suggests that MTL dysregulation occurs prior to clinical symptoms of dementia in APOE*4 carriers... - Midlife memory improvement predicts preservation of hippocampal volume in old agePaul R Borghesani
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA
Neurobiol Aging 33:1148-55. 2012..These findings suggest that improvement in memory in midlife is associated with sparing of hippocampal volume in later life... - Magnetic resonance spectroscopy outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disordersSusan J Astley
Department of Epidemiology, University of Washington, Seattle, WA 98195, USA
Magn Reson Imaging 27:760-78. 2009..NAA and Cre concentrations did not vary significantly. This study provides further evidence of the vulnerability of the cholinergic system in FASD... - Change in MRI striatal volumes as a biomarker in preclinical Huntington's diseaseElizabeth H Aylward
Department of Radiology, University of Washington, Seattle, WA 98195, USA
Brain Res Bull 72:152-8. 2007..This strategy is essential if efficient and cost-effective clinical trials are to be conducted in the preclinical stage of Huntington's disease... - Brain volume and shape in infants with deformational plagiocephalyBrent R Collett
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
Childs Nerv Syst 28:1083-90. 2012..Although the mechanisms accounting for these delays are unknown, one hypothesis focuses on underlying differences in brain development. In this study, we used MRI to examine brain volume and shape in infants with and without DP... - MRI volumes of amygdala and hippocampus in non-mentally retarded autistic adolescents and adultsE H Aylward
Department of Radiology, University of Washington School of Medicine, Seattle 98195, USA
Neurology 53:2145-50. 1999..To determine whether volumes of hippocampus and amygdala are abnormal in people with autism... - Brain structural abnormalities in young children with autism spectrum disorderB F Sparks
Department of Radiology, University of Washington School of Medicine, Seattle, WA 98105, USA
Neurology 59:184-92. 2002..Research currently is underway to better elucidate mechanisms underlying these structural abnormalities and their longitudinal progression... - Beyond disgust: impaired recognition of negative emotions prior to diagnosis in Huntington's diseaseShannon A Johnson
Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA
Brain 130:1732-44. 2007..In contrast to previous results, we found no evidence of relative impairments in recognizing disgust or fear, and no evidence to support a link between the striatum and disgust recognition... - Regional white matter change in pre-symptomatic Huntington's disease: a diffusion tensor imaging studySarah A J Reading
Division of Psychiatric Neuroimaging, Department of Psychiatry, The Johns Hopkins University, Phipps 313, Baltimore, MD 21287, USA
Psychiatry Res 140:55-62. 2005..Our results indicate that, before the onset of manifest HD, there are regional decreases in fractional anisotropy, indicating early white matter disorganization... - Anatomical correlates of dyslexia: frontal and cerebellar findingsMark A Eckert
Department of Neuroscience, McKnight Brain Institute of the University of Florida, Gainesville, FL 32610, USA
Brain 126:482-94. 2003..This study may be the first to show that anomalies in a cerebellar-frontal circuit are associated with rapid automatic naming and the double-deficit subtype of dyslexia... - Verbal episodic memory declines prior to diagnosis in Huntington's diseaseAndrea C Solomon
Department of Psychological and Brain Sciences, Indiana University, 1101 E 10th Street, Bloomington, IN 47405, USA
Neuropsychologia 45:1767-76. 2007..These findings indicate that verbal episodic memory is affected in early pre-diagnostic HD and may decline as striatal volumes decrease and individuals approach the motor diagnostic threshold... - Effect of long-term corticosteroid use on bone mineral density in children: a prospective longitudinal assessment in the childhood Asthma Management Program (CAMP) studyH William Kelly
Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131 0001, USA
Pediatrics 122:e53-61. 2008..Thus, we assessed the effects of multiple short courses of oral corticosteroids and long-term inhaled corticosteroids on bone mineral accretion over a period of years... - Offering to share: how to put heads together in autism neuroimagingMatthew K Belmonte
Department of Human Development, Cornell University, Martha Van Rensselaer Hall, Ithaca, NY 14853 4401, USA
J Autism Dev Disord 38:2-13. 2008..A theme in these requirements is the need to preserve creative approaches and risk-taking within individual laboratories at the same time as common standards are provided for these laboratories to build on...