Research Topics
| Andrew AvinsSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Safety and Toxicity of Saw Palmetto in the CAMUS TrialAndrew L Avins
Northern California Kaiser Permanente Division of Research, Oakland and Departments of Medicine and Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California Electronic address
J Urol 189:1415-20. 2013..While the most recent data from double-blind clinical trials do not support efficacy superior to that of placebo, there are sparse data on saw palmetto toxicity...
Should we reconsider the routine use of placebo controls in clinical research?Andrew L Avins
Northern California Kaiser Permanente Division of Research, 2000 Broadway, Oakland, CA 94612, USA
Trials 13:44. 2012..An unrecognized consequence of this preference is that clinicians are more limited in their ability to provide the benefits of the non-specific healing effects of placebos in clinical practice...
Study protocol- Lumbar Epidural steroid injections for Spinal Stenosis (LESS): a double-blind randomized controlled trial of epidural steroid injections for lumbar spinal stenosis among older adultsJanna L Friedly
Comparative Effectiveness, Cost and Outcomes Research Center, University of Washington, Seattle, USA
BMC Musculoskelet Disord 13:48. 2012....
Characteristics of patients with chronic back pain who benefit from acupunctureKaren J Sherman
Group Health Research Institute, Seattle, USA
BMC Musculoskelet Disord 10:114. 2009..As part of a large trial evaluating acupuncture for chronic low back pain, we sought to identify subgroups of participants that were particularly responsive to acupuncture...
Comparing recruitment strategies in a study of acupuncture for chronic back painKaren J Sherman
Group Health Research Institute, 1730 Minor Avenue, Suite 1600, Seattle, WA 98101, USA
BMC Med Res Methodol 9:69. 2009..Little is known about how the use of different recruitment strategies affects the types of individuals choosing to participate or the conclusions of the study...
Placebo adherence and its association with morbidity and mortality in the studies of left ventricular dysfunctionAndrew L Avins
Northern California Kaiser Permanente Division of Research, Oakland, CA 94612, USA
J Gen Intern Med 25:1275-81. 2010....
A detailed safety assessment of a saw palmetto extractAndrew L Avins
Division of Research, Northern California Kaiser Permanente, San Francisco, CA, USA
Complement Ther Med 16:147-54. 2008..Saw palmetto is commonly used by men for lower-urinary tract symptoms. Despite its widespread use, very little is known about the potential toxicity of this dietary supplement...
Hepatic effects of lovastatin exposure in patients with liver disease: a retrospective cohort studyAndrew L Avins
Kaiser Permanente Division of Research, Oakland, CA 94612, USA
Drug Saf 31:325-34. 2008..Little is known about the potential adverse hepatic effects of HMG-CoA reductase inhibitors ('statins') in patients with existing liver disease; therefore, we examined the risk of liver toxicity with lovastatin exposure in these patients...
Creating a culture of researchAndrew L Avins
Northern California Kaiser Permanente Division of Research, Oakland, California 94612, United States
Contemp Clin Trials 28:557-62. 2007....
Comparison of dual-energy X-ray absorptiometry and magnetic resonance imaging-measured adipose tissue depots in HIV-infected and control subjectsRebecca Scherzer
University of California, San Francisco, CA 94121, USA
Am J Clin Nutr 88:1088-96. 2008....
Simple anthropometric measures correlate with metabolic risk indicators as strongly as magnetic resonance imaging-measured adipose tissue depots in both HIV-infected and control subjectsRebecca Scherzer
Northern California Institute for Research and Education, San Francisco, CA, USA
Am J Clin Nutr 87:1809-17. 2008..Studies in persons without HIV infection have compared percentage body fat (%BF) and waist circumference as markers of risk for the complications of excess adiposity, but only limited study has been conducted in HIV-infected subjects...
Saw palmetto and lower urinary tract symptoms: what is the latest evidence?Andrew L Avins
Northern California Kaiser Permanente Division of Research, 2000 Broadway, 3rd Floor, Oakland, CA 94612, USA
Curr Urol Rep 7:260-5. 2006..Higher-quality studies are currently underway to better define the potential benefits and risks of plant-based extracts for treating symptoms related to benign prostatic hyperplasia...
Feasibility of conducting a clinical trial on Hatha yoga for chronic low back pain: methodological lessonsBradly P Jacobs
Osher Center for Integrative Medicine, Department of Family and Community Medicine, University of California, San Francisco, USA
Altern Ther Health Med 10:80-3. 2004
Use of an embedded N-of-1 trial to improve adherence and increase information from a clinical studyAndrew L Avins
Northern California Kaiser Permanente Division of Research, Oakland, CA 94612, United States
Contemp Clin Trials 26:397-401. 2005..Wider use of formal N-of-1 studies may be a valuable tool for improving adherence and determining whether observed side effects are caused by study medication in clinical trials...
Spontaneous bleeding associated with ginkgo biloba: a case report and systematic review of the literature: a case report and systematic review of the literatureStephen Bent
Osher Center for Integrative Medicine, University of California, San Francisco, USA
J Gen Intern Med 20:657-61. 2005..Ginkgo biloba (ginkgo) is a herbal remedy used by over 2% of the adult population in the United States. Several review articles have suggested that ginkgo may increase the risk of bleeding...
Saw palmetto for benign prostatic hyperplasiaStephen Bent
Osher Center for Integrative Medicine, Department of Medicine, University of California, San Francisco, San Francisco, USA
N Engl J Med 354:557-66. 2006..Saw palmetto is used by over 2 million men in the United States for the treatment of benign prostatic hyperplasia and is commonly recommended as an alternative to drugs approved by the Food and Drug Administration...
Brief communication: Better ways to question patients about adverse medical events: a randomized, controlled trialStephen Bent
University of California and San Francisco Veterans Administration Medical Center, San Francisco, California 94121, USA
Ann Intern Med 144:257-61. 2006..There is no standard method of identifying adverse events in clinical trials...
A novel clinical-trial design for the study of massage therapyMichael Patterson
Osher Center for Integrative Medicine, University of California, San Francisco, CA, USA
Complement Ther Med 16:169-76. 2008..To develop and test the feasibility and acceptability of a structured design for a massage therapy clinical trial that included a treatment arm designed to control for the non-specific effects of a massage therapy intervention...
Effect of intense lifestyle modification and cardiac rehabilitation on psychosocial cardiovascular disease risk factors and quality of lifeSteven G Aldana
College of Health and Human Performance, Brigham Young University, USA
Behav Modif 30:507-25. 2006..The rehabilitation group improved in 7 of the 12, and the control group showed significant improvements in 6 of the variables. Intensive lifestyle modification programs significantly affect psychosocial risk factors and quality of life...
The influence of an intense cardiovascular disease risk factor modification programSteven G Aldana
College of Health and Human Performance, Brigham Young University, Provo, UT 84602 2214, USA
Prev Cardiol 7:19-25. 2004....
Cardiovascular risk reductions associated with aggressive lifestyle modification and cardiac rehabilitationSteven G Aldana
College of Health and Human Performance, Brigham Young University, Provo, Utah 84602, USA
Heart Lung 32:374-82. 2003....
Research Grants
- SAW PALMETTO EXTRACT IN BENIGN PROSTATIC HYPERPLASIAAndrew Avins; Fiscal Year: 2003..Numerous laboratory parameters will measured at intervals throughout the trial and symptomatic side effects will be assessed. ..
- The Enigma of Placebo Adherence and Health OutcomesAndrew Avins; Fiscal Year: 2007..The results of this investigation will shed important light on powerful biomedical and non-biomedical determinants of health outcomes that, at present, are insufficiently documented and poorly understood. ..
- The Enigma of Placebo Adherence and Health OutcomesAndrew Avins; Fiscal Year: 2009..The results of this investigation will shed important light on powerful biomedical and non-biomedical determinants of health outcomes that, at present, are insufficiently documented and poorly understood. ..
