Christy L Avery

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Fine-mapping and initial characterization of QT interval loci in African Americans
    Christy L Avery
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS Genet 8:e1002870. 2012
  2. pmc Impact of long-term measures of glucose and blood pressure on the retinal microvasculature
    Christy L Avery
    Department of Epidemiology, University of North Carolina Chapel Hill, 137 E Franklin St, Suite 306, Chapel Hill, NC 27514, USA
    Atherosclerosis 225:412-7. 2012
  3. pmc The population burden of heart failure attributable to modifiable risk factors: the ARIC (Atherosclerosis Risk in Communities) study
    Christy L Avery
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27514, USA
    J Am Coll Cardiol 60:1640-6. 2012
  4. pmc Quantitative trait locus-specific genotype x alcoholism interaction on linkage for evoked electroencephalogram oscillations
    Lisa J Martin
    Center for Epidemiology and Biostatistics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    BMC Genet 6:S123. 2005
  5. pmc A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains
    Christy L Avery
    Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS Genet 7:e1002322. 2011
  6. pmc Long-term association between self-reported signs and symptoms and heart failure hospitalizations: the Atherosclerosis Risk In Communities (ARIC) Study
    Christy L Avery
    Department of Epidemiology, University of North Carolina at Chapel Hill, Bank of America Center, 137 E Franklin St, Suite 306, Chapel Hill, NC 27514, USA
    Eur J Heart Fail 12:232-8. 2010
  7. doi request reprint Estimating error in using ambient PM2.5 concentrations as proxies for personal exposures: a review
    Christy L Avery
    Department of Epidemiology, University of North Carolina Chapel Hill, Bank of America Center, 137 E Franklin St, Suite 306, Chapel Hill, NC 27514
    Epidemiology 21:215-23. 2010
  8. pmc Estimating error in using residential outdoor PM2.5 concentrations as proxies for personal exposures: a meta-analysis
    Christy L Avery
    Department of Epidemiology, University of North Carolina Chapel Hill, Chapel Hill, North Carolina 27514, USA
    Environ Health Perspect 118:673-8. 2010
  9. pmc Genetic association studies and the effect of misclassification and selection bias in putative confounders
    Christy L Avery
    Department of Epidemiology, University of North Carolina, 137 East Franklin Street, CB 8050, Suite 306, Chapel Hill, North Carolina 27514 USA
    BMC Proc 3:S48. 2009
  10. pmc Accuracy of haplotype estimation in a region of low linkage disequilibrium
    Christy L Avery
    Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA
    BMC Genet 6:S80. 2005

Detail Information

Publications21

  1. pmc Fine-mapping and initial characterization of QT interval loci in African Americans
    Christy L Avery
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS Genet 8:e1002870. 2012
    ....
  2. pmc Impact of long-term measures of glucose and blood pressure on the retinal microvasculature
    Christy L Avery
    Department of Epidemiology, University of North Carolina Chapel Hill, 137 E Franklin St, Suite 306, Chapel Hill, NC 27514, USA
    Atherosclerosis 225:412-7. 2012
    ....
  3. pmc The population burden of heart failure attributable to modifiable risk factors: the ARIC (Atherosclerosis Risk in Communities) study
    Christy L Avery
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27514, USA
    J Am Coll Cardiol 60:1640-6. 2012
    ..The goal of this study was to estimate the population burden of heart failure and the influence of modifiable risk factors...
  4. pmc Quantitative trait locus-specific genotype x alcoholism interaction on linkage for evoked electroencephalogram oscillations
    Lisa J Martin
    Center for Epidemiology and Biostatistics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    BMC Genet 6:S123. 2005
    ..1). Further, we detected QTL-specific genotype x alcoholism interaction at these loci. This work demonstrates the importance of considering the complexity of common complex traits in our search for genes that predispose to alcoholism...
  5. pmc A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains
    Christy L Avery
    Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS Genet 7:e1002322. 2011
    ..These pleiotropic loci may help characterize metabolic dysregulation and identify targets for intervention...
  6. pmc Long-term association between self-reported signs and symptoms and heart failure hospitalizations: the Atherosclerosis Risk In Communities (ARIC) Study
    Christy L Avery
    Department of Epidemiology, University of North Carolina at Chapel Hill, Bank of America Center, 137 E Franklin St, Suite 306, Chapel Hill, NC 27514, USA
    Eur J Heart Fail 12:232-8. 2010
    ..Although studies of the accuracy of heart failure (HF) classification scoring systems are available, few have examined their performance when restricted to self-reported items...
  7. doi request reprint Estimating error in using ambient PM2.5 concentrations as proxies for personal exposures: a review
    Christy L Avery
    Department of Epidemiology, University of North Carolina Chapel Hill, Bank of America Center, 137 E Franklin St, Suite 306, Chapel Hill, NC 27514
    Epidemiology 21:215-23. 2010
    ..Such methods commonly rely on the estimated correlation between ambient and personal PM(2.5) concentrations (r). However, studies of r have not been systematically and quantitatively assessed for publication bias or heterogeneity...
  8. pmc Estimating error in using residential outdoor PM2.5 concentrations as proxies for personal exposures: a meta-analysis
    Christy L Avery
    Department of Epidemiology, University of North Carolina Chapel Hill, Chapel Hill, North Carolina 27514, USA
    Environ Health Perspect 118:673-8. 2010
    ..5. An alternative proxy-the residential outdoor PM2.5 concentration measured adjacent to participant homes-has few advantages under this assumption...
  9. pmc Genetic association studies and the effect of misclassification and selection bias in putative confounders
    Christy L Avery
    Department of Epidemiology, University of North Carolina, 137 East Franklin Street, CB 8050, Suite 306, Chapel Hill, North Carolina 27514 USA
    BMC Proc 3:S48. 2009
    ..These results support careful consideration of how well a study population represents the target population because selection bias may result even when associations are modest...
  10. pmc Accuracy of haplotype estimation in a region of low linkage disequilibrium
    Christy L Avery
    Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA
    BMC Genet 6:S80. 2005
    ....
  11. pmc NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: the Atherosclerosis Risk in Communities study
    Craig R Lee
    Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27709, USA
    Pharmacogenet Genomics 16:891-9. 2006
    ..We sought to determine whether cigarette smoking modified the association between NOS3 polymorphisms and risk of coronary heart disease or stroke...
  12. doi request reprint Single nucleotide polymorphisms in nucleotide excision repair genes, cancer treatment, and head and neck cancer survival
    Annah B Wyss
    Department of Epidemiology, Gillings School of Global Pubic Health, University of North Carolina at Chapel Hill, 2101B McGavran Greenberg Hall, CB 7435, Chapel Hill, NC, 27599, USA
    Cancer Causes Control 25:437-50. 2014
    ..Because nucleotide excision repair (NER) enzymes remove adducts, variants in NER genes may be associated with survival among HNC cases both independently and jointly with treatment...
  13. pmc Variation in the checkpoint kinase 2 gene is associated with type 2 diabetes in multiple populations
    Kari E North
    Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA
    Acta Diabetol 47:199-207. 2010
    ..These results may suggest a new pathway in the pathogenesis of type 2 diabetes that involves pancreatic beta-cell damage and apoptosis...
  14. doi request reprint Estimating personal exposures from ambient air pollution measures: using meta-analysis to assess measurement error
    Katelyn M Holliday
    From the aDepartment of Epidemiology, University of North Carolina, Chapel Hill, NC bHealth Sciences Library, University of North Carolina, Chapel Hill, NC cUnited States Environmental Protection Agency, Research Triangle Park, Durham, NC dDepartment of Public Health Sciences, Pennsylvania State University, Hershey, PA eStatistical and Mathematical Sciences Institute, Research Triangle Park, Durham, NC fDepartment of Statistics and Operations Research, University of North Carolina, Chapel Hill, NC and gDepartment of Medicine, University of North Carolina, Chapel Hill, NC
    Epidemiology 25:35-43. 2014
    ..Factors underlying this variation and its effect on health outcome-PM exposure relationships remain poorly understood...
  15. doi request reprint Sources of variability in measurements of cardiac troponin T in a community-based sample: the atherosclerosis risk in communities study
    Sunil K Agarwal
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Clin Chem 57:891-7. 2011
    ..Using a highly sensitive assay for measurement, we evaluated the long-term storage stability of plasma cTnT at -70 °C and the sources of cTnT variability...
  16. pmc Single-nucleotide polymorphisms in nucleotide excision repair genes, cigarette smoking, and the risk of head and neck cancer
    Annah B Wyss
    Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina 27599, USA
    Cancer Epidemiol Biomarkers Prev 22:1428-45. 2013
    ..Nucleotide excision repair (NER) genes encode enzymes that remove adducts and may be independently associated with HNC, as well as modifiers of the association between smoking and HNC...
  17. pmc Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts
    Anne M Butler
    Department of Epidemiology, University of North Carolina, Chapel Hill, 27514, USA
    Circ Cardiovasc Genet 5:639-46. 2012
    ..However, few studies have examined loci associated with PR in African Americans...
  18. doi request reprint The environmental epidemiology of atrial arrhythmogenesis
    Eric A Whitsel
    University of North Carolina, Chapel Hill, Department of Epidemiology, Chapel Hill, NC 27514, USA
    J Epidemiol Community Health 64:587-90. 2010
    ..approaches to evaluation of susceptibility; and 4. strategies for informing regulatory policies designed to help control population-level risks for CVD...
  19. ncbi request reprint Linkage analysis of diabetes status among hypertensive families: the Hypertension Genetic Epidemiology Network study
    Christy L Avery
    Department of Epidemiology, University of North Carolina Chapel Hill, Chapel Hill, NC 27514, USA
    Diabetes 53:3307-12. 2004
    ..The identification and replication of type 2 diabetes QTLs will bring us closer to the detection of functional genes that influence diabetes susceptibility...
  20. doi request reprint Comparison of study designs used to detect and characterize pharmacogenomic interactions in nonexperimental studies: a simulation study
    Christy L Avery
    Departments of aEpidemiology bMedicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Pharmacogenet Genomics 24:146-55. 2014
    ..We, therefore, compared the two designs [the overall population (OPD) and the treated-only (TOD) design] by simulating a pharmacogenomic study of the ECG QT interval (QT)...
  21. ncbi request reprint Genetic epidemiology: the potential benefits and challenges of using genetic information to improve human health
    Amanda A Seyerle
    Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Franklin Street Plaza, 137 E Franklin St, Ste 306, Chapel Hill, NC 27514, USA
    N C Med J 74:505-8. 2013
    ..Genetic epidemiology has the potential to significantly affect human health. This commentary examines major developments in the field's history, promising avenues of research, and possible challenges faced by genetic epidemiologists. ..