B B Avants

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint The shape operator for differential analysis of images
    Brian Avants
    University of Pennsylvania, Philadelphia, PA 19104 6389, USA
    Inf Process Med Imaging 18:101-13. 2003
  2. ncbi request reprint Lagrangian frame diffeomorphic image registration: Morphometric comparison of human and chimpanzee cortex
    Brian B Avants
    Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104 6389, USA
    Med Image Anal 10:397-412. 2006
  3. ncbi request reprint Spatiotemporal normalization for longitudinal analysis of gray matter atrophy in frontotemporal dementia
    Brian Avants
    Dept of Radiology, University of Pennsylvania, Philadelphia, PA 19104 6389, USA
    Med Image Comput Comput Assist Interv 10:303-10. 2007
  4. pmc The optimal template effect in hippocampus studies of diseased populations
    Brian B Avants
    Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuroimage 49:2457-66. 2010
  5. ncbi request reprint Effects of heavy in utero cocaine exposure on adolescent caudate morphology
    Brian B Avants
    Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Pediatr Neurol 37:275-9. 2007
  6. pmc Symmetric diffeomorphic image registration with cross-correlation: evaluating automated labeling of elderly and neurodegenerative brain
    B B Avants
    Department of Radiology, University of Pennsylvania, 3600 Market Street, Philadelphia, PA 19104, United States
    Med Image Anal 12:26-41. 2008
  7. pmc Dementia induces correlated reductions in white matter integrity and cortical thickness: a multivariate neuroimaging study with sparse canonical correlation analysis
    Brian B Avants
    Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104 6389, USA
    Neuroimage 50:1004-16. 2010
  8. ncbi request reprint Multivariate normalization with symmetric diffeomorphisms for multivariate studies
    B B Avants
    Penn Image Computing and Science Laboratory, University of Pennsylvania, Philadelphia, PA 19104 6389, USA
    Med Image Comput Comput Assist Interv 10:359-66. 2007
  9. pmc A reproducible evaluation of ANTs similarity metric performance in brain image registration
    Brian B Avants
    Penn Image Computing and Science Laboratory, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuroimage 54:2033-44. 2011
  10. pmc Sparse unbiased analysis of anatomical variance in longitudinal imaging
    Brian Avants
    Dept of Radiology, University of Pennsylvania, Philadelphia, PA 19104 6389 USA
    Med Image Comput Comput Assist Interv 13:324-31. 2010

Detail Information

Publications28

  1. ncbi request reprint The shape operator for differential analysis of images
    Brian Avants
    University of Pennsylvania, Philadelphia, PA 19104 6389, USA
    Inf Process Med Imaging 18:101-13. 2003
    ..A novel variant of Demons registration, extensible for use with differentiable similarity metrics, is also applied for deformable curvature-driven registration of medical images...
  2. ncbi request reprint Lagrangian frame diffeomorphic image registration: Morphometric comparison of human and chimpanzee cortex
    Brian B Avants
    Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104 6389, USA
    Med Image Anal 10:397-412. 2006
    ..The population statistics show a significant doubling of the relative prefrontal lobe size in humans, as compared to chimpanzees...
  3. ncbi request reprint Spatiotemporal normalization for longitudinal analysis of gray matter atrophy in frontotemporal dementia
    Brian Avants
    Dept of Radiology, University of Pennsylvania, Philadelphia, PA 19104 6389, USA
    Med Image Comput Comput Assist Interv 10:303-10. 2007
    ..This paper shows the statistical power of symmetric diffeomorphic normalization for performing deformation-based studies of longitudinal atrophy...
  4. pmc The optimal template effect in hippocampus studies of diseased populations
    Brian B Avants
    Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuroimage 49:2457-66. 2010
    ..Furthermore, explicit geometric optimization of the shape component of the unbiased template positively impacts the study of diseased hippocampi...
  5. ncbi request reprint Effects of heavy in utero cocaine exposure on adolescent caudate morphology
    Brian B Avants
    Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Pediatr Neurol 37:275-9. 2007
    ..The right (P < 0.025) and left (P < 0.035) caudate, studied independently, show the same significant trend. Permutation testing and the false discovery rate were used to assess significance...
  6. pmc Symmetric diffeomorphic image registration with cross-correlation: evaluating automated labeling of elderly and neurodegenerative brain
    B B Avants
    Department of Radiology, University of Pennsylvania, 3600 Market Street, Philadelphia, PA 19104, United States
    Med Image Anal 12:26-41. 2008
    ..This study indicates that SyN, with cross-correlation, is a reliable method for normalizing and making anatomical measurements in volumetric MRI of patients and at-risk elderly individuals...
  7. pmc Dementia induces correlated reductions in white matter integrity and cortical thickness: a multivariate neuroimaging study with sparse canonical correlation analysis
    Brian B Avants
    Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104 6389, USA
    Neuroimage 50:1004-16. 2010
    ..We conclude that SCCA is a potentially valuable approach in image analysis that can be applied productively to distinguishing between neurodegenerative conditions...
  8. ncbi request reprint Multivariate normalization with symmetric diffeomorphisms for multivariate studies
    B B Avants
    Penn Image Computing and Science Laboratory, University of Pennsylvania, Philadelphia, PA 19104 6389, USA
    Med Image Comput Comput Assist Interv 10:359-66. 2007
    ..In this initial study, we develop the theory for Multivariate Symmetric Normalization (MVSyN), establish its feasibility and discuss preliminary results on a multivariate statistical study of 22q deletion syndrome...
  9. pmc A reproducible evaluation of ANTs similarity metric performance in brain image registration
    Brian B Avants
    Penn Image Computing and Science Laboratory, University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuroimage 54:2033-44. 2011
    ..This is the first study to use a consistent transformation framework to provide a reproducible evaluation of the isolated effect of the similarity metric on optimal template construction and brain labeling...
  10. pmc Sparse unbiased analysis of anatomical variance in longitudinal imaging
    Brian Avants
    Dept of Radiology, University of Pennsylvania, Philadelphia, PA 19104 6389 USA
    Med Image Comput Comput Assist Interv 13:324-31. 2010
    ....
  11. ncbi request reprint The correlation of cognitive decline with frontotemporal dementia induced annualized gray matter loss using diffeomorphic morphometry
    Brian Avants
    University of Pennsylvania School of Medicine, Philadelphia, 19104 6389, USA
    Alzheimer Dis Assoc Disord 19:S25-8. 2005
    ..This study gives insight into the relationship between FTD-related progressive cortical atrophy and loss in cognitive function...
  12. ncbi request reprint Geodesic estimation for large deformation anatomical shape averaging and interpolation
    Brian Avants
    University of Pennsylvania, Philadelphia, PA 19104, USA
    Neuroimage 23:S139-50. 2004
    ..The procedures generate improved average representations of highly variable anatomy from distinct populations...
  13. pmc Speech errors in progressive non-fluent aphasia
    Sharon Ash
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4283, USA
    Brain Lang 113:13-20. 2010
    ..We conclude that the speech errors produced by PNFA patients are mainly errors at the phonemic level of language processing and are not caused by a motor planning impairment...
  14. pmc The role of ventral medial prefrontal cortex in social decisions: converging evidence from fMRI and frontotemporal lobar degeneration
    Murray Grossman
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4283, USA
    Neuropsychologia 48:3505-12. 2010
    ..These converging results support the role of vmPFC in social decision-making where potentially negative consequences must be considered...
  15. ncbi request reprint Characterization of sexual dimorphism in the human corpus callosum
    Abraham Dubb
    Department of Bioengineering, Psychiatry, and Radiology, University of Pennsylvania, Philadelphia, PA 19104 6389, USA
    Neuroimage 20:512-9. 2003
    ..Our results demonstrate significant morphologic differences in the corpus callosum between genders and a possible sex difference in the neuro-developmental cycle...
  16. pmc A learning-based wrapper method to correct systematic errors in automatic image segmentation: consistently improved performance in hippocampus, cortex and brain segmentation
    Hongzhi Wang
    Penn Image Computing and Science Laboratory, Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA
    Neuroimage 55:968-85. 2011
    ..908 for normal controls and 0.893 for patients with mild cognitive impairment. Average Dice overlaps of 0.964, 0.905 and 0.951 are obtained for brain extraction, white matter segmentation and gray matter segmentation, respectively...
  17. ncbi request reprint Integrated graph cuts for brain MRI segmentation
    Zhuang Song
    Penn Image Computing and Science Lab, University of Pennsylvania, USA
    Med Image Comput Comput Assist Interv 9:831-8. 2006
    ..In the experiments of real neonatal brain MRIs, the results of the proposed method have good overlap with the manual segmentations by human experts...
  18. pmc Hierarchical organization of scripts: converging evidence from FMRI and frontotemporal degeneration
    Christine Farag
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4283, USA
    Cereb Cortex 20:2453-63. 2010
    ..Our findings suggest that frontal cortex contributes to clustering events during script comprehension, underlining the role of frontal cortex in the hierarchical organization of a script...
  19. pmc Standing on the shoulders of giants: improving medical image segmentation via bias correction
    Hongzhi Wang
    Department of Radiology, University of Pennsylvania, USA
    Med Image Comput Comput Assist Interv 13:105-12. 2010
    ..We apply this methodology on three segmentation problems/methods and show significant improvements for all of them...
  20. pmc Neuroanatomy of apathy and disinhibition in frontotemporal lobar degeneration
    Lauren Massimo
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Dement Geriatr Cogn Disord 27:96-104. 2009
    ..To investigate the neural basis for the behavioral symptoms of frontotemporal lobar degeneration (FTLD) that cause the greatest caregiver distress...
  21. pmc Structural consequences of diffuse traumatic brain injury: a large deformation tensor-based morphometry study
    Junghoon Kim
    Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network, Philadelphia, PA 19141, USA
    Neuroimage 39:1014-26. 2008
    ....
  22. pmc Reversal of the concreteness effect in semantic dementia
    Michael F Bonner
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4283, USA
    Cogn Neuropsychol 26:568-79. 2009
    ..These observations raise the possibility that degraded visual feature knowledge contributes in part to the impaired comprehension of concrete words in SD...
  23. doi request reprint Multivariate analysis of structural and diffusion imaging in traumatic brain injury
    Brian Avants
    Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Acad Radiol 15:1360-75. 2008
    ..We use this technique to study MV effects of traumatic brain injury (TBI)...
  24. ncbi request reprint Towards a dynamic model of pulmonary parenchymal deformation: evaluation of methods for temporal reparameterization of lung data
    Tessa A Sundaram
    University of Pennsylvania, Philadelphia PA 19104, USA
    Med Image Comput Comput Assist Interv 8:328-35. 2005
    ..Our ultimate goal is to be able to characterize normal parenchymal biomechanics over a population of healthy individuals, and to use this statistical model to evaluate lung deformation under various pathological states...
  25. ncbi request reprint Multivariate examination of brain abnormality using both structural and functional MRI
    Yong Fan
    Department of Radiology, University of Pennsylvania, PA 19104, USA
    Neuroimage 36:1189-99. 2007
    ..Therefore, the proposed approach provided not only a multivariate classification method for detecting brain abnormalities, but also an alternative way for group analysis of multimodality images...
  26. pmc Canine and human visual cortex intact and responsive despite early retinal blindness from RPE65 mutation
    Geoffrey K Aguirre
    Department of Neurology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS Med 4:e230. 2007
    ..We therefore studied the cortex of RPE65-mutant dogs before and after retinal gene therapy. Then, we inquired whether there is visual pathway integrity and responsivity in adult humans with LCA due to RPE65 mutations (RPE65-LCA)...
  27. ncbi request reprint High-dimensional spatial normalization of diffusion tensor images improves the detection of white matter differences: an example study using amyotrophic lateral sclerosis
    Hui Zhang
    Penn Image Computing and Science Laboratory, University of Pennsylvania, Philadelphia, PA 19104, USA
    IEEE Trans Med Imaging 26:1585-97. 2007
    ..We also found that high-dimensional approaches, by leveraging full tensor features instead of tensor-derived indices, can further improve the alignment of WM tracts...
  28. ncbi request reprint Altered resting cerebral blood flow in adolescents with in utero cocaine exposure revealed by perfusion functional MRI
    Hengyi Rao
    Department of Radiology and Neurology, Center for Functional Neuroimaging, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Pediatrics 120:e1245-54. 2007
    ....