Affiliation: University of Wisconsin
- Steroid receptor control of reproductive behaviorAnthony P Auger
Department of Psychology, University of Wisconsin Madison, Madison, WI 53706, USA
Horm Behav 45:168-72. 2004..For example, progestin receptors in rodent brain are sensitive to progesterone and to social cues in the environment. This review discusses these emerging mechanisms for steroid receptor control in developing and adult brain...
- Permanent and plastic epigenesis in neuroendocrine systemsCatherine J Auger
Neuroscience Training Program and Department of Psychology, University of Wisconsin Madison, Madison, WI 53706, USA
Front Neuroendocrinol 34:190-7. 2013..As epigenetic mechanisms can either be stable or plastic, elucidating the mechanisms involved in reversing these processes could aid in understanding how to reverse pathological epigenetic programming. ..
- Epigenetic turn ons and turn offs: chromatin reorganization and brain differentiationAnthony P Auger
Department of Psychology, 1202 West Johnson Street, Madison, Wisconsin 53706, USA
Endocrinology 152:349-53. 2011..This minireview will discuss how epigenetic events influence sexual differentiation of the brain and point at examples suggesting that some epigenetic events can be quite dynamic...
- Epigenetic organization of brain sex differences and juvenile social play behaviorAnthony P Auger
Psychology Department and Neuroscience Training Program, 1202 West Johnson Street, University of Wisconsin Madison, Madison, WI 53706, USA
Horm Behav 59:358-63. 2011..Specifically, we will discuss new data on sex differences in ERα DNA promoter methylation patterns, and the role of MeCP2 and the nuclear corepressor, NCoR, on the organization of juvenile social play behavior...
- Sex differences in the developing brain: crossroads in the phosphorylation of cAMP response element binding proteinA P Auger
Department of Psychology, University of Wisconsin Madison, Madison, WI 53706, USA
J Neuroendocrinol 15:622-7. 2003..The potential consequences of this divergence in the regulation of CREB are discussed in relation to adult sexually dimorphic brain morphology, physiology and behaviour...
- Brain sex differences and the organisation of juvenile social play behaviourA P Auger
Psychology Department, University of Wisconsin, Madison, WI 53706, USA
J Neuroendocrinol 21:519-25. 2009....
- Corepressors, nuclear receptors, and epigenetic factors on DNA: a tail of repressionAnthony P Auger
Psychology Department, 1202 West Johnson Street, University of Wisconsin Madison, Madison, WI 53706, USA
Psychoneuroendocrinology 34:S39-47. 2009..We will discuss how coregulators influence gene transcription and repression, the role of chromatin-binding factors in the regulation of gene transcription, and their potential impact on brain development...
- Altered gene expression in mice selected for high maternal aggressionS C Gammie
Department of Zoology, and Neuroscience Training Program, University of Wisconsin, Madison, WI 53706, USA
Genes Brain Behav 6:432-43. 2007..Together, this study provides a list of candidate genes (some previously implicated in maternal aggression and some novel) that may play an important role in the production of this behavior...
- Sex differences in Fos protein expression in the neonatal rat brainK M Olesen
Department of Psychology, University of Wisconsin, Madison, WI 53706, USA
J Neuroendocrinol 17:255-61. 2005..These data indicate a sex difference in Fos protein expression during brain development, suggesting a potential role for Fos in differentiating male from female rat brain...
- Altered dopamine signaling in naturally occurring maternal neglectStephen C Gammie
Department of Zoology, University of Wisconsin Madison, Madison, Wisconsin, United States of America
PLoS ONE 3:e1974. 2008..Child neglect is the most common form of child maltreatment, yet the biological basis of maternal neglect is poorly understood and a rodent model is lacking...
- Nuclear receptor coactivators modulate hormone-dependent gene expression in brain and female reproductive behavior in ratsHeather A Molenda
Center for Neuroendocrine Studies and Neuroscience and Behavior Program, University of Massachusetts, Amherst, Massachusetts 01003, USA
Endocrinology 143:436-44. 2002..These findings indicate that these nuclear receptor coactivators function in brain to modulate ER transcriptional activity and the expression of hormone-dependent behavior...
- Microarray profiling of gene expression patterns in adult male rat brain following acute progesterone treatmentCatherine J Auger
Department of Zoology, Birge Hall, 430 Lincoln Drive, University of Wisconsin, Madison, WI 53706, USA
Brain Res 1067:58-66. 2006..We confirmed the data gathered from the arrays on 4 different genes using Real-Time PCR. These data begin to outline the important role played by progesterone in mediating changes in gene expression within the male brain...
- Gene array profiling of large hypothalamic CNS regions in lactating and randomly cycling virgin miceStephen C Gammie
Department of Zoology, University of Wisconsin, 1117 W Johnson Street, Madison, WI 53706, USA
Brain Res Mol Brain Res 139:201-11. 2005..Together, our findings provide possible new material on gene expression changes that may support maternal behaviors. The advantages and drawbacks of sampling large CNS regions using arrays are discussed...
- Dopaminergic activation of estrogen receptors in neonatal brain alters progestin receptor expression and juvenile social play behaviorKristin M Olesen
Department of Psychology, University of Wisconsin, Madison, 1202 West Johnson Street, Madison, Wisconsin 53706, USA
Endocrinology 146:3705-12. 2005..This suggests that changes in dopamine transmission in developing brain can activate estrogen receptors in a ligand-independent manner to influence gene expression and have lasting consequences on social behavior...
- Expression of the nuclear receptor coactivator, cAMP response element-binding protein, is sexually dimorphic and modulates sexual differentiation of neonatal rat brainAnthony P Auger
Department of Physiology, University of Maryland, Baltimore, MD 21201, USA
Endocrinology 143:3009-16. 2002..These results indicate that CBP expression in developing rat brain is sexually dimorphic and an important modulator for steroid hormone action...
- Sex difference in mecp2 expression during a critical period of rat brain developmentJoseph R Kurian
Psychology Department, University of Wisconsin Madison, Madison, Wisconsin, USA
Epigenetics 2:173-8. 2007..Considering the strong link between MeCP2 and neurodevelopmental disorders, the lower levels of mecp2 expression in males may also underlie a biological risk for mecp2-related neural disorders...
- Dopaminergic activation of estrogen receptors induces fos expression within restricted regions of the neonatal female rat brainKristin M Olesen
Department of Psychology, University of Wisconsin, Madison, Wisconsin, United States of America
PLoS ONE 3:e2177. 2008..This implies that ligand-independent activation of estrogen receptors by dopamine might organize a unique set of behaviors during brain development in contrast to the more wide spread ligand activation of estrogen receptors by estrogen...
- Mecp2 organizes juvenile social behavior in a sex-specific mannerJoseph R Kurian
Department of Psychology, and Neuroscience Training Program, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
J Neurosci 28:7137-42. 2008..This suggests that Mecp2 may have an overlooked role in the organization of sexually dimorphic behaviors and that male juvenile behavior is particularly sensitive to Mecp2 disruption during this period of development...
- Getting excited about GABA and sex differences in the brainMargaret M McCarthy
Department of Physiology, University of Maryland Baltimore, 655 W Baltimore Street, Baltimore, MD 21201, USA
Trends Neurosci 25:307-12. 2002..This is the first identification of a pivotal point in brain development that dictates the sex differences evident in adult physiology and behavior...
- Effects of prenatal chlordecone on sexually differentiated behavior in adult ratsSusan A Laessig
Program in Toxicology, University of Maryland Medical System, Baltimore, MD 21201 USA
Neurotoxicol Teratol 29:255-63. 2007..Permanent changes in adult behavior were consistent with both estrogenic and anti-estrogenic actions following developmental exposure to CD at the dose tested...