Research Topics
Genomes and GenesSpecies | Janet AudrainSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Publications
Where is the pleasure in that? Low hedonic capacity predicts smoking onset and escalationJanet Audrain-McGovern
Department of Psychiatry and Abramson Cancer Center, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA
Nicotine Tob Res 14:1187-96. 2012..The present study sought to provide initial evidence for a relationship between hedonic capacity and adolescent smoking onset and escalation...
Longitudinal variation in adolescent physical activity patterns and the emergence of tobacco useJanet Audrain-McGovern
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
J Pediatr Psychol 37:622-33. 2012..The objective of this investigation was to examine how variation in adolescent physical activity is related to smoking and alternative tobacco use...
Applying a behavioral economic framework to understanding adolescent smokingJanet Audrain-McGovern
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
Psychol Addict Behav 18:64-73. 2004..Adolescents who smoke may have fewer reinforcers that protect against smoking and more reinforcers that promote smoking. Discounting of future rewards affects smoking through reinforcer type...
Predictors of participation in a smoking cessation program among young adult smokersJanet Audrain-McGovern
Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA
Cancer Epidemiol Biomarkers Prev 16:617-9. 2007....
Effect of team sport participation on genetic predisposition to adolescent smoking progressionJanet Audrain-McGovern
Tobacco Use Research Center, Department of Psychiatry, University of Pennsylvania, PA 19104, USA
Arch Gen Psychiatry 63:433-41. 2006..There is much to be learned about why some adolescents progress to a regular smoking habit and others do not...
Interacting effects of genetic predisposition and depression on adolescent smoking progressionJanet Audrain-McGovern
Department of Psychiatry, Abramson Cancer Center, University of Pennsylvania, Suite 4100, 3535 Market Street, Philadelphia, PA 19104, USA
Am J Psychiatry 161:1224-30. 2004..The goal of the present study was to identify specific genetic associations with smoking progression in adolescents and to determine whether these genetic effects on smoking practices are potentiated by depression symptoms...
The role of CYP2A6 in the emergence of nicotine dependence in adolescentsJanet Audrain-McGovern
Tobacco Use Research Center, Department of Psychiatry, University of Pennsylvania, 3535 Market St, Philadelphia, PA 19104, USA
Pediatrics 119:e264-74. 2007....
How do psychological factors influence adolescent smoking progression? The evidence for indirect effects through tobacco advertising receptivityJanet Audrain-McGovern
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
Pediatrics 117:1216-25. 2006..To determine whether novelty seeking and depressive symptoms had mediated or indirect effects on adolescent smoking progression through tobacco advertising receptivity...
Identifying and characterizing adolescent smoking trajectoriesJanet Audrain-McGovern
Department of Psychiatry and Abramson Cancer Center, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA
Cancer Epidemiol Biomarkers Prev 13:2023-34. 2004..Adolescent smoking prevention and intervention programs will need to consider this heterogeneity and tailor or enhance attention to risk and protective factors depending on the subpopulation...
The impact of self-control indices on peer smoking and adolescent smoking progressionJanet Audrain-McGovern
Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, Pennsylvania 19104, USA
J Pediatr Psychol 31:139-51. 2006..To determine the direct impact of self-control variables on baseline smoking and smoking progression and determine whether self-control had indirect effects on smoking practices through effects on peer smoking...
Does delay discounting play an etiological role in smoking or is it a consequence of smoking?Janet Audrain-McGovern
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
Drug Alcohol Depend 103:99-106. 2009....
Young adult smoking: what factors differentiate ex-smokers, smoking cessation treatment seekers and nontreatment seekers?Janet Audrain-McGovern
Department of Psychiatry, University of Pennsylvania, Suite 4100, Philadelphia, PA 19104, USA
Addict Behav 34:1036-41. 2009..These results highlight variables that may be important to consider in recruitment strategies and treatment components for smoking cessation interventions for young adult smokers...
Declining alternative reinforcers link depression to young adult smokingJanet Audrain-McGovern
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
Addiction 106:178-87. 2011..We sought to evaluate the role of depression symptoms in young adult smoking uptake and to evaluate whether non-smoking related alternative reinforcers was a mechanism by which depression symptoms influence smoking...
Physical activity in first-degree relatives of breast cancer patientsJ Audrain
Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Philadelphia, Pennsylvania 19104 3309, USA
J Behav Med 24:587-603. 2001....
Recruiting adolescents into genetic studies of smoking behaviorJanet Audrain
Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Cancer Epidemiol Biomarkers Prev 11:249-52. 2002..43; confidence interval = 1.37-4.32, P = 0.003)...
The efficacy of motivational interviewing versus brief advice for adolescent smoking behavior changeJanet Audrain-McGovern
Department of Psychiatry, University of Pennsylvania, 3535 Market St, Suite 4100, Philadelphia, PA 19104, USA
Pediatrics 128:e101-11. 2011..In this study we sought to evaluate the efficacy of motivational interviewing (MI) compared with structured brief advice (SBA) for adolescent smoking behavior change...
Adolescent smoking and depression: evidence for self-medication and peer smoking mediationJanet Audrain-McGovern
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
Addiction 104:1743-56. 2009..The present study sought to clarify the temporal precedence for smoking and depression and to determine whether these variables are linked indirectly through peer smoking...
Effecting behavior change: awareness of family historyJanet Audrain-McGovern
Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA
Am J Prev Med 24:183-9. 2003....
Which adolescents are most receptive to tobacco industry marketing? implications for counter-advertising campaignsJanet Audrain-McGovern
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
Health Commun 15:499-513. 2003..Counter-advertising messages should consider individual differences in novelty-seeking, because novelty-seekers may be most receptive to tobacco industry promotional campaigns...
Smoking progression and physical activityJanet Audrain-McGovern
Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Cancer Epidemiol Biomarkers Prev 12:1121-9. 2003..05). Higher levels of physical activity may reduce the risk of smoking during adolescence. Youth smoking prevention initiatives should incorporate strategies to promote physical activity to prevent smoking experimentation and escalation...
Effects of dopamine transporter and receptor polymorphisms on smoking cessation in a bupropion clinical trialCaryn Lerman
University of Pennsylvania, Dept of Psychiatry, Abramson Cancer Ctr, Philadelphia, PA 19104, USA
Health Psychol 22:541-8. 2003..These results provide the first evidence from a prospective clinical trial that genes that alter dopamine function may influence smoking cessation and relapse during the treatment phase...
Pharmacogenetic investigation of smoking cessation treatmentCaryn Lerman
Department of Psychiatry, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA
Pharmacogenetics 12:627-34. 2002..Such research could ultimately enable practitioners to select the optimal type and dose of medication for individual smokers...
Can the blind see? Participant guess about treatment arm assignment may influence outcome in a clinical trial of bupropion for smoking cessationRobert A Schnoll
Department of Psychiatry, The University of Pennsylvania, Philadelphia, PA 19104, USA
J Subst Abuse Treat 34:234-41. 2008..There was no evidence for mediation. In bupropion smoking cessation trials, blind failure may occur and participant guess about treatment arm assignment is associated with quit rates...
Associations between relationship support and psychological reactions of participants and partners to BRCA1 and BRCA2 testing in a clinic-based sampleSharon Manne
Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Ann Behav Med 28:211-25. 2004....
Attention-Deficit Hyperactivity Disorder (ADHD) symptoms and smoking patterns among participants in a smoking-cessation programC Lerman
University of Pennsylvania, 3535 Market St, Suite 4100, Philadelphia, PA 19104, USA
Nicotine Tob Res 3:353-9. 2001..Future studies of the role of inattention symptoms in response to smoking treatment are warranted...
Developmental heterogeneity in adolescent depressive symptoms: associations with smoking behaviorDaniel Rodriguez
Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA
Psychosom Med 67:200-10. 2005..We sought to understand this relationship better in a prospective study by investigating whether there are subpopulations of adolescents with different relationships between smoking and depressive symptoms...
Experiences with weight change in African-American breast cancer survivorsChanita Hughes Halbert
Department of Psychiatry, Abramson Cancer Center, and Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Breast J 14:182-7. 2008..It may be important to provide African-American breast cancer survivors with information about the causes and implications of weight change and strategies for weight control after treatment as part of their follow-up care...
A randomized, controlled trial of financial incentives for smoking cessationKevin G Volpp
Center for Health Equity Research and Promotion, Philadelphia Veterans Affairs Medical Center, Philadelphia, USA
N Engl J Med 360:699-709. 2009....
Smoking-related weight concerns among underserved, black maternal smokersBradley N Collins
Department of Public Health and Pediatrics, Health Behavior Research Center, Temple University, Philadelphia, PA 19122, USA
Am J Health Behav 33:699-709. 2009..To expand understanding of a smoking cessation barrier for women, weight concerns, in a medically underserved population...
Team sport participation and smoking: analysis with general growth mixture modelingDaniel Rodriguez
Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Pediatr Psychol 29:299-308. 2004..To assess the likelihood of smoking among adolescents with different patterns of team sport participation, grades 9-11...
Recurrent event analysis of lapse and recovery in a smoking cessation clinical trial using bupropionE Paul Wileyto
University of Pennsylvania, Tobacco Use Research Center, Philadelphia, PA 19104 3309, USA
Nicotine Tob Res 7:257-68. 2005..Further research disentangling lapse and recovery events from summary abstinence measures is needed to help us develop interventions that take advantage of bupropion at its best and that compensate where it is weak...
Cigarette smoking practices among American college students: review and future directionsFreda Patterson
Department of Psychiatry, University of Pennsylvania, Philadelphia, USA
J Am Coll Health 52:203-10. 2004..Such information could inform the development of smoking prevention and cessation interventions targeted to the college student population...
Using logistic regression to estimate delay-discounting functionsE Paul Wileyto
Tobacco Use Research Center, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA
Behav Res Methods Instrum Comput 36:41-51. 2004..51), and the results were highly correlated (rho = .973). Simulated MCQ data showed that k was unbiased, except where beta 1 > or = -1, indicating a vague survey response. Jackknife standard errors provided excellent coverage...
Contextual consistency and adolescent smoking: testing the indirect effect of home indoor smoking restrictions on adolescent smoking through peer smokingDaniel Rodriguez
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
Nicotine Tob Res 9:1155-61. 2007..90 to -.24), offering some preliminary ideas about why home indoor smoking restrictions reduce the risk of adolescent smoking. However, the nature and stability of these effects on adolescent smoking behavior remain to be investigated...
Physical activity, global physical self-concept, and adolescent smokingDaniel Rodriguez
Department of Psychiatry, University of Pennsylvania, Philadelphic 19104, USA
Ann Behav Med 30:251-9. 2005..One such variable is global physical self-concept (GPSC). Briefly, GPSC is a general perception of one's physical self, including appearance and physical activity competence...
Effect of bupropion on depression symptoms in a smoking cessation clinical trialCaryn Lerman
Department of Psychiatry, Abramson Family Cancer Research Institute, University of Pennsylvania Cancer Center, Philadelphia, PA, USA
Psychol Addict Behav 18:362-6. 2004....
Construct validity analysis of the early smoking experience questionnaire for adolescentsDaniel Rodriguez
Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA
Addict Behav 29:1053-7. 2004..A cross-structure analysis with related and unrelated constructs supports the convergent and discriminant validity of the measure for an adolescent population...
Effects of different nicotine replacement therapies on postcessation psychological responsesAndrew A Strasser
Tobacco Use Research Center, Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19140 3309, USA
Addict Behav 30:9-17. 2005..These findings indicate that, although TN may enhance positive affect for smokers in treatment compared with NS, only changes in negative affect predict treatment outcome...
Beliefs about the risks of smoking mediate the relationship between exposure to smoking and smokingDaniel Rodriguez
Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA
Psychosom Med 69:106-13. 2007....
Do small lapses predict relapse to smoking behavior under bupropion treatment?Paul Wileyto
University of Pennsylvania, Philadelphia, PA 19104 3309, USA
Nicotine Tob Res 6:357-66. 2004....
Effects of inattention and hyperactivity/impulsivity symptoms on development of nicotine dependence from mid adolescence to young adulthoodDaniel Rodriguez
Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA
J Pediatr Psychol 33:563-75. 2008..We sought to assess the relationship of ADHD Hyperactivity-Impulsivity (H/I) and Inattention (I) symptoms with ND symptoms in a community sample from adolescence to young adulthood (ages 18-21)...
Tryptophan hydroxylase gene variant and smoking behaviorC Lerman
Psychiatry Department, University of Pennsylvania Health Sciences, Philadelphia, PA, USA
Am J Med Genet 105:518-20. 2001..Future family-based studies are needed to confirm this finding. Published 2001 Wiley-Liss, Inc...
Mediating mechanisms for the impact of bupropion in smoking cessation treatmentCaryn Lerman
Cancer Center and Department of Psychiatry, University of Pennsylvania Health Sciences, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA
Drug Alcohol Depend 67:219-23. 2002..Laboratory-based paradigms may be useful to identify other mediators of bupropion's effects, thereby pointing to mechanisms of effect that can be bolstered in future treatment studies...
Translating basic science to improve pharmacotherapy for nicotine dependenceJennifer M Phillips
University of Pennsylvania, Philadelphia, Pennsylvania, USA
Nicotine Tob Res 9:S583-98. 2007....
Research Grants
- A Behavioral Economic Approach to Smoking CessationJanet Audrain McGovern; Fiscal Year: 2007..g., adolescents, older adults) and to other contexts (e.g., prevention). ..
- HEALTH PROMOTION FOR WOMEN AT RISK FOR BREAST CANCERJanet Audrain McGovern; Fiscal Year: 2002..The information obtained from this project should be applicable to groups at high risk for developing other cancers (e.g., colon cancer). ..
- Longitudinal Patterns and Predictors of Smoking BehaviorJanet Audrain McGovern; Fiscal Year: 2007..Results from this study can be used to inform the timing, level, type, and specific target of smoking interventions. ..
- A Behavioral Economic Approach to Smoking CessationJanet Audrain McGovern; Fiscal Year: 2003..The long-term objective is to provide information about a potentially more robust model of smoking behavior that can be applied to other populations (e.g., adolescents, older adults) and to other contexts (e.g., prevention). ..
- The Protective Effects of Physical Activity on AdolescentSmoking ProgressionJANET E AUDRAIN MCGOVERN; Fiscal Year: 2010..This information is critical to for determining the content, timing, and targets for youth smoking prevention intervention that incorporates a physical activity component. ..
