Research Topics
| Audrey L AtkinSummaryAffiliation: University of Nebraska Country: USA Publications
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Publications
Yeast bioinformatics and strain engineering resourcesAudrey L Atkin
School of Biological Sciences, University of Nebraska Lincoln, Lincoln, NE, USA
Methods Mol Biol 765:173-87. 2011..cerevisiae genes and identification of homologs, strategies for integration and analysis of gene expression data, and the genetic resources available for doing experiments using S. cerevisiae...
Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth inductionBessie W Kebaara
School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
Eukaryot Cell 7:980-7. 2008..These levels of excess farnesol are sufficient to block filamentation in a wild-type strain. Our data are consistent with the role of Tup1 as a crucial component of the response to farnesol in C. albicans...- Activity and toxicity of farnesol towards Candida albicans are dependent on growth conditionsMelanie L Langford
School of Biological Sciences, University of Nebraska Lincoln, 1901 Vine St, Rm E146, Lincoln, NE 68588 0666, USA
Antimicrob Agents Chemother 54:940-2. 2010..This study clearly defines what farnesol concentrations are lethal to C. albicans, based on environmental conditions... - Arginine-induced germ tube formation in Candida albicans is essential for escape from murine macrophage line RAW 264.7Suman Ghosh
School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
Infect Immun 77:1596-605. 2009..Therefore, metabolism of arginine by C. albicans controls hyphal switching and provides an important mechanism for escaping host defense... - Long 3'-UTRs target wild-type mRNAs for nonsense-mediated mRNA decay in Saccharomyces cerevisiaeBessie W Kebaara
School of Biological Sciences, University of Nebraska Lincoln, Lincoln, NE 68588, USA
Nucleic Acids Res 37:2771-8. 2009..Finally, we show that nmd mutants are sensitive to Calcofluor White, which suggests that the regulation of PGA1 and other cell wall biosynthesis proteins by NMD is physiologically significant... - Cellular interactions of farnesol, a quorum-sensing molecule produced by Candida albicansMelanie L Langford
School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
Future Microbiol 4:1353-62. 2009..It is intriguing that we still do not know precisely how farnesol works, but interference with the Ras1-cAMP pathway is part of the story... - Regulation of aromatic alcohol production in Candida albicansSuman Ghosh
School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
Appl Environ Microbiol 74:7211-8. 2008..ARO8 and ARO9 were alkaline upregulated, while ARO10 was alkaline downregulated. The alkaline-dependent change in expression of ARO8 was Rim101 independent, while the expression of ARO9 was Rim101 dependent... - Quorum sensing in dimorphic fungi: farnesol and beyondKenneth W Nickerson
School of Biological Sciences, University of Nebraska, Lincoln, NE 68588-0666, USA
Appl Environ Microbiol 72:3805-13. 2006 - In vivo and in vitro anaerobic mating in Candida albicansRaluca Dumitru
School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
Eukaryot Cell 6:465-72. 2007..These cells were true mating products because they were tetraploid, mononuclear, and prototrophic, and they contained the heterologous hisG marker from one of the parental strains... - N5-phosphonoacetyl-L-ornithine (PALO): a convenient synthesis and investigation of influence on regulation of amino acid biosynthetic genes in Saccharomyces cerevisiaeBrad Johnson
Department of Chemistry, University of Nebraska Lincoln, Lincoln, NE 68588 0304, USA
Bioorg Med Chem Lett 21:2351-3. 2011..Investigations in the model organism Saccharomyces cerevisiae found that, in contrast to a previous report, PALO did not influence growth rate or expression of genes involved in arginine metabolism... 
Determination of mRNA half-lives in Candida albicans using thiolutin as a transcription inhibitorBessie W Kebaara
School of Biological Sciences, University of Nebraska-Lincoln, NE 68588-0666, USA
Genome 49:894-9. 2006..The mRNA decay rates obtained are compared with those for orthologous mRNAs from Saccharomyces cerevisiae. This procedure should work for a broad range of C. albicans strains and can be adapted to other fungal species...- Gene set coregulated by the Saccharomyces cerevisiae nonsense-mediated mRNA decay pathwayRachel Taylor
School of Biological Sciences, University of Nebraska-Lincoln, NE 68588-0666, USA
Eukaryot Cell 4:2066-77. 2005..This strategy is significant because it allows us to classify the genes regulated by NMD into functionally related sets, an important step toward understanding the role NMD plays in the normal functioning of yeast cells... - Farnesol restores wild-type colony morphology to 96% of Candida albicans colony morphology variants recovered following treatment with mutagensEllen C Jensen
School of Biological Sciences, College of Saint Benedict's and Saint John's University, Collegeville, MN 56321, USA
Genome 49:346-53. 2006..Additionally, 9 mutants chosen at random were screened for farnesol production. Two mutants failed to produce detectable levels of farnesol... - Farnesol concentrations required to block germ tube formation in Candida albicans in the presence and absence of serumDaniel D Mosel
School of Biological Sciences, University of Nebraska, Lincoln, NE 68588-0666, USA
Appl Environ Microbiol 71:4938-40. 2005..For defined media, 1 to 2 microM farnesol was sufficient. However, with serum at 2 to 20%, up to 250 microM farnesol was required. Farnesol blocked germ tube formation but did not block elongation of existing germ tubes...