Audrey L Atkin

Summary

Affiliation: University of Nebraska
Country: USA

Publications

  1. pmc Long 3'-UTRs target wild-type mRNAs for nonsense-mediated mRNA decay in Saccharomyces cerevisiae
    Bessie W Kebaara
    School of Biological Sciences, University of Nebraska Lincoln, Lincoln, NE 68588, USA
    Nucleic Acids Res 37:2771-8. 2009
  2. doi request reprint Yeast bioinformatics and strain engineering resources
    Audrey L Atkin
    School of Biological Sciences, University of Nebraska Lincoln, Lincoln, NE, USA
    Methods Mol Biol 765:173-87. 2011
  3. ncbi request reprint Upf1p, a highly conserved protein required for nonsense-mediated mRNA decay, interacts with the nuclear pore proteins Nup100p and Nup116p
    Tara Nazarenus
    University of Nebraska Lincoln, School of Biological Sciences, E146 Beadle Center, Lincoln, Nebraska 68588 0666, USA
    Gene 345:199-212. 2005
  4. pmc Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction
    Bessie W Kebaara
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
    Eukaryot Cell 7:980-7. 2008
  5. pmc Gene set coregulated by the Saccharomyces cerevisiae nonsense-mediated mRNA decay pathway
    Rachel Taylor
    School of Biological Sciences, University of Nebraska Lincoln, NE 68588 0666, USA
    Eukaryot Cell 4:2066-77. 2005
  6. pmc Candida albicans Czf1 and Efg1 coordinate the response to farnesol during quorum sensing, white-opaque thermal dimorphism, and cell death
    Melanie L Langford
    School of Biological Sciences, University of Nebraska Lincoln, Lincoln, Nebraska, USA
    Eukaryot Cell 12:1281-92. 2013
  7. pmc Activity and toxicity of farnesol towards Candida albicans are dependent on growth conditions
    Melanie L Langford
    School of Biological Sciences, University of Nebraska Lincoln, 1901 Vine St, Rm E146, Lincoln, NE 68588 0666, USA
    Antimicrob Agents Chemother 54:940-2. 2010
  8. pmc Arginine-induced germ tube formation in Candida albicans is essential for escape from murine macrophage line RAW 264.7
    Suman Ghosh
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
    Infect Immun 77:1596-605. 2009
  9. ncbi request reprint Saccharomyces cerevisiae Ats1p interacts with Nap1p, a cytoplasmic protein that controls bud morphogenesis
    Christina M Shields
    School of Biological Sciences, University of Nebraska Lincoln, Lincoln, NE 68588 0666, USA
    Curr Genet 44:184-94. 2003
  10. doi request reprint Cellular interactions of farnesol, a quorum-sensing molecule produced by Candida albicans
    Melanie L Langford
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
    Future Microbiol 4:1353-62. 2009

Collaborators

  • Kenneth W Nickerson
  • Melanie L Langford
  • Jacob M Hornby
  • Thomas M Petro
  • Malcolm Whiteway
  • Daniel Dignard
  • Bessie W Kebaara
  • Suman Ghosh
  • Tara Nazarenus
  • Rachel Taylor
  • Raluca Dumitru
  • Dhammika H M L P Navarathna
  • Brad Johnson
  • Ellen C Jensen
  • Daniel D Mosel
  • Bessie Wanja Kebaara
  • Ann Hou
  • Alexis Haifley
  • Joseph Cheatle
  • Christina M Shields
  • Bessie Kebaara
  • Rachel Steadman
  • Patrick Dussault
  • Jeffrey J Bunker
  • Krista D Patefield
  • Jake T Cooper
  • David D Roberts
  • Christian G Elowsky
  • Razvan V Dumitru
  • Camile P Semighini
  • Lindsey E Nielsen
  • Nicole E Pagliaccetti
  • Chuleeon M Wolter
  • Rachel Uhrenholdt
  • Rena Yamanaka
  • Amanda Forch
  • Ashley Jones
  • Jason P Wendler
  • Kate Stoysich
  • Rebecca Cedarberg
  • Ryan Bell
  • Christina Shields
  • Audrey Tapprich

Detail Information

Publications18

  1. pmc Long 3'-UTRs target wild-type mRNAs for nonsense-mediated mRNA decay in Saccharomyces cerevisiae
    Bessie W Kebaara
    School of Biological Sciences, University of Nebraska Lincoln, Lincoln, NE 68588, USA
    Nucleic Acids Res 37:2771-8. 2009
    ..Finally, we show that nmd mutants are sensitive to Calcofluor White, which suggests that the regulation of PGA1 and other cell wall biosynthesis proteins by NMD is physiologically significant...
  2. doi request reprint Yeast bioinformatics and strain engineering resources
    Audrey L Atkin
    School of Biological Sciences, University of Nebraska Lincoln, Lincoln, NE, USA
    Methods Mol Biol 765:173-87. 2011
    ..cerevisiae genes and identification of homologs, strategies for integration and analysis of gene expression data, and the genetic resources available for doing experiments using S. cerevisiae...
  3. ncbi request reprint Upf1p, a highly conserved protein required for nonsense-mediated mRNA decay, interacts with the nuclear pore proteins Nup100p and Nup116p
    Tara Nazarenus
    University of Nebraska Lincoln, School of Biological Sciences, E146 Beadle Center, Lincoln, Nebraska 68588 0666, USA
    Gene 345:199-212. 2005
    ....
  4. pmc Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction
    Bessie W Kebaara
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
    Eukaryot Cell 7:980-7. 2008
    ..These levels of excess farnesol are sufficient to block filamentation in a wild-type strain. Our data are consistent with the role of Tup1 as a crucial component of the response to farnesol in C. albicans...
  5. pmc Gene set coregulated by the Saccharomyces cerevisiae nonsense-mediated mRNA decay pathway
    Rachel Taylor
    School of Biological Sciences, University of Nebraska Lincoln, NE 68588 0666, USA
    Eukaryot Cell 4:2066-77. 2005
    ..This strategy is significant because it allows us to classify the genes regulated by NMD into functionally related sets, an important step toward understanding the role NMD plays in the normal functioning of yeast cells...
  6. pmc Candida albicans Czf1 and Efg1 coordinate the response to farnesol during quorum sensing, white-opaque thermal dimorphism, and cell death
    Melanie L Langford
    School of Biological Sciences, University of Nebraska Lincoln, Lincoln, Nebraska, USA
    Eukaryot Cell 12:1281-92. 2013
    ..These results highlight a new role for Czf1 as a downstream effector of the morphological response to farnesol, and along with Efg1, Czf1 is involved in the control of farnesol-mediated cell death in C. albicans. ..
  7. pmc Activity and toxicity of farnesol towards Candida albicans are dependent on growth conditions
    Melanie L Langford
    School of Biological Sciences, University of Nebraska Lincoln, 1901 Vine St, Rm E146, Lincoln, NE 68588 0666, USA
    Antimicrob Agents Chemother 54:940-2. 2010
    ..This study clearly defines what farnesol concentrations are lethal to C. albicans, based on environmental conditions...
  8. pmc Arginine-induced germ tube formation in Candida albicans is essential for escape from murine macrophage line RAW 264.7
    Suman Ghosh
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
    Infect Immun 77:1596-605. 2009
    ..Therefore, metabolism of arginine by C. albicans controls hyphal switching and provides an important mechanism for escaping host defense...
  9. ncbi request reprint Saccharomyces cerevisiae Ats1p interacts with Nap1p, a cytoplasmic protein that controls bud morphogenesis
    Christina M Shields
    School of Biological Sciences, University of Nebraska Lincoln, Lincoln, NE 68588 0666, USA
    Curr Genet 44:184-94. 2003
    ..Our results suggest Ats1p might regulate coordination of the microtubule state with the cell cycle through an interaction with Nap1p...
  10. doi request reprint Cellular interactions of farnesol, a quorum-sensing molecule produced by Candida albicans
    Melanie L Langford
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
    Future Microbiol 4:1353-62. 2009
    ..It is intriguing that we still do not know precisely how farnesol works, but interference with the Ras1-cAMP pathway is part of the story...
  11. pmc Regulation of aromatic alcohol production in Candida albicans
    Suman Ghosh
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
    Appl Environ Microbiol 74:7211-8. 2008
    ..ARO8 and ARO9 were alkaline upregulated, while ARO10 was alkaline downregulated. The alkaline-dependent change in expression of ARO8 was Rim101 independent, while the expression of ARO9 was Rim101 dependent...
  12. pmc Quorum sensing in dimorphic fungi: farnesol and beyond
    Kenneth W Nickerson
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
    Appl Environ Microbiol 72:3805-13. 2006
  13. ncbi request reprint Genetic background affects relative nonsense mRNA accumulation in wild-type and upf mutant yeast strains
    Bessie Kebaara
    School of Biological Sciences, University of Nebraska Lincoln, Lincoln, NE 68588 0666, USA
    Curr Genet 43:171-7. 2003
    ..These results suggest there are genes that influence the efficiency of NMD and that yeast strains derived from the W303 background may be useful for measurement of abundance and half-lives of low abundance, short-lived NMD substrates...
  14. ncbi request reprint Determination of mRNA half-lives in Candida albicans using thiolutin as a transcription inhibitor
    Bessie W Kebaara
    School of Biological Sciences, University of Nebraska Lincoln, NE 68588 0666, USA
    Genome 49:894-9. 2006
    ..The mRNA decay rates obtained are compared with those for orthologous mRNAs from Saccharomyces cerevisiae. This procedure should work for a broad range of C. albicans strains and can be adapted to other fungal species...
  15. pmc In vivo and in vitro anaerobic mating in Candida albicans
    Raluca Dumitru
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
    Eukaryot Cell 6:465-72. 2007
    ..These cells were true mating products because they were tetraploid, mononuclear, and prototrophic, and they contained the heterologous hisG marker from one of the parental strains...
  16. doi request reprint N5-phosphonoacetyl-L-ornithine (PALO): a convenient synthesis and investigation of influence on regulation of amino acid biosynthetic genes in Saccharomyces cerevisiae
    Brad Johnson
    Department of Chemistry, University of Nebraska Lincoln, Lincoln, NE 68588 0304, USA
    Bioorg Med Chem Lett 21:2351-3. 2011
    ..Investigations in the model organism Saccharomyces cerevisiae found that, in contrast to a previous report, PALO did not influence growth rate or expression of genes involved in arginine metabolism...
  17. ncbi request reprint Farnesol restores wild-type colony morphology to 96% of Candida albicans colony morphology variants recovered following treatment with mutagens
    Ellen C Jensen
    School of Biological Sciences, College of Saint Benedict s and Saint John s University, Collegeville, MN 56321, USA
    Genome 49:346-53. 2006
    ..Additionally, 9 mutants chosen at random were screened for farnesol production. Two mutants failed to produce detectable levels of farnesol...
  18. pmc Farnesol concentrations required to block germ tube formation in Candida albicans in the presence and absence of serum
    Daniel D Mosel
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588 0666, USA
    Appl Environ Microbiol 71:4938-40. 2005
    ..For defined media, 1 to 2 microM farnesol was sufficient. However, with serum at 2 to 20%, up to 250 microM farnesol was required. Farnesol blocked germ tube formation but did not block elongation of existing germ tubes...