D M Asmuth
Affiliation: University of California
- Randomized pilot trial of a synbiotic dietary supplement in chronic HIV-1 infectionMarco Schunter
Department of Medical Microbiology and Immunology, University of California, Davis, CA, USA
BMC Complement Altern Med 12:84. 2012..Known properties of pre-, pro-, and synbiotics suggest that they may be useful tools in achieving this goal...
- Gastrointestinal-associated lymphoid tissue immune reconstitution in a randomized clinical trial of raltegravir versus non-nucleoside reverse transcriptase inhibitor-based regimensDavid M Asmuth
University of California Davis Medical School, Sacramento, CA 95817, USA
AIDS 26:1625-34. 2012..To examine immune restoration in duodenal tissue and correlates of reduction of immune activation in chronic HIV-infected patients randomized to different treatment regimens...
- Pegylated interferon-alpha 2a treatment of chronic SIV-infected macaquesD M Asmuth
Division of Infectious Diseases, Department of Internal Medicine, University of California Davis Medical Center, 4150 V Street, Sacramento, CA 95817, USA
J Med Primatol 37:26-30. 2008..Limited investigations have explored the innate or adaptive immune responses of IFN-alpha on SIV replication in vivo...
- Safety, tolerability, and mechanisms of antiretroviral activity of pegylated interferon Alfa-2a in HIV-1-monoinfected participants: a phase II clinical trialDavid M Asmuth
Division of Infectious Diseases, University of California Davis Medical School, 4150 V Street, Sacramento, CA 95817 1460, USA
J Infect Dis 201:1686-96. 2010..To our knowledge, the antiviral activity of pegylated interferon alfa-2a has not been studied in participants with untreated human immunodeficiency virus type 1 (HIV-1) infection but without chronic hepatitis C virus (HCV) infection...
- Comparative cell-mediated immunogenicity of DNA/DNA, DNA/adenovirus type 5 (Ad5), or Ad5/Ad5 HIV-1 clade B gag vaccine prime-boost regimensDavid M Asmuth
Division of Infectious Disease, Department of Internal Medicine, University of California at Davis, Sacramento, CA 95618, USA
J Infect Dis 201:132-41. 2010..We report composite results from the Merck phase I program of near-consensus clade B human immunodeficiency virus (HIV) type 1 gag vaccines...
- Treatments for hepatitis BDavid M Asmuth
Division of Infectious Diseases, Dept of Internal Medicine, UC Davis Medical Center, 4150 V St, PSSB G500, Sacramento, CA 95817, USA
Clin Infect Dis 39:1353-62. 2004..However, there remain many challenges in understanding the implications of drug resistance, the role of combination therapy, and how to define the response to therapy within subsets of patients with hepatitis B...
- Hydroxyurea in combination with didanosine and stavudine in antiretroviral-experienced HIV-infected subjects with a review of the literatureR Rossero
Department of Medicine, Division of Infectious Diseases, University of Texas Medical Branch, Galveston, USA
Int J STD AIDS 14:350-5. 2003..The results support the need for a randomized, prospective study to determine the safety and efficacy of hydroxyurea plus didanosine in antiretroviral-experienced patients with CD4(+) cell counts below 300 cells/mm(3)...
- Hepatitis B and C viral load changes following initiation of highly active antiretroviral therapy (HAART) in patients with advanced HIV infectionDavid M Asmuth
Department of Internal Medicine, University of California Davis Medical Center, Sacramento, CA, USA
Antiviral Res 63:123-31. 2004....
- Absence of HBV and HCV, HTLV-I and -II, and human herpes virus-8 activation after allogeneic RBC transfusion in patients with advanced HIV-1 infectionDavid M Asmuth
Department of Internal Medicine, Division of Infectious Diseases and Immunology, University of California Davis Medical Center, 4150 V Street, Suite 6200 PSSB, Sacramento, CA 95817, USA
Transfusion 43:451-8. 2003....
- Replication capacity in relation to immunologic and virologic outcomes in HIV-1-infected treatment-naive subjectsGail Skowron
Division of Infectious Diseases, Roger Williams Medical Center, Providence, RI 02908, USA
J Acquir Immune Defic Syndr 50:250-8. 2009..To evaluate the association between baseline (BL) replication capacity (RC) (RCBL) and immunologic/virologic parameters (at BL and after 48 weeks on therapy) in HIV-1-infected subjects initiating antiretroviral therapy...
- CD4+ T-cell restoration after 48 weeks in the maraviroc treatment-experienced trials MOTIVATE 1 and 2David M Asmuth
University of California Davis, Sacramento, CA, USA
J Acquir Immune Defic Syndr 54:394-7. 2010..To determine factors associated with CD4 responses to maraviroc (MVC)-containing regimens in treatment-experienced patients...
- Cell cycle kinetic dysregulation in HIV-infected normal lymphocytesDavid M Asmuth
Department of Internal Medicine, University of California Davis, Sacramento, California
Cytometry A 66:41-51. 2005....
- Multifunctional human immunodeficiency virus (HIV) gag-specific CD8+ T-cell responses in rectal mucosa and peripheral blood mononuclear cells during chronic HIV type 1 infectionJ William Critchfield
Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, CA 95616, USA
J Virol 81:5460-71. 2007..These findings demonstrate that rectal CD8(+) T cells are capable of robust and varied HIV-1-specific responses and therefore likely play an active role in eliminating infected cells during chronic infection...
- Effect of baseline- and treatment-related factors on immunologic recovery after initiation of antiretroviral therapy in HIV-1-positive subjects: results from ACTG 384Rajesh T Gandhi
Massachusetts General Hospital, Boston, MA, USA
J Acquir Immune Defic Syndr 42:426-34. 2006..To assess the effect of baseline- and treatment-related factors on immunologic recovery after initiation of antiretroviral therapy (ART)...
- A phase II, double-masked, randomized, placebo-controlled evaluation of a human monoclonal anti-Cytomegalovirus antibody (MSL-109) in combination with standard therapy versus standard therapy alone in the treatment of AIDS patients with Cytomegalovirus reMichael J Borucki
University of Texas Health Center, Tyler, TX, USA
Antiviral Res 64:103-11. 2004....
- Cytomegalovirus glycoprotein B groups in human immunodeficiency virus-infected patients with incident retinitisW Lawrence Drew
Mount Zion Medical Center, University of California, San Francisco, CA 94115, USA
J Infect Dis 186:114-7. 2002..These rates were similar among case patients and control subjects and were similar by risk group. The CMV gB2 genotype is not a major determinant of retinitis pathogenicity but appears to be highly prevalent among HIV-infected patients...