Research Topics
| D AskenaziSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Detail Information
Publications
Fluid overload and mortality are associated with acute kidney injury in sick near-term/term neonateDavid J Askenazi
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
Pediatr Nephrol 28:661-6. 2013..Acute kidney injury (AKI) is common and portends mortality in several neonatal cohorts. Fluid overload is independently associated with poor outcomes in children and adults but has not been extensively studied in neonates...
Continuous renal replacement therapy for children ≤10 kg: a report from the prospective pediatric continuous renal replacement therapy registryDavid J Askenazi
University of Alabama at Birmingham, Children s of Alabama, Birmingham, AL 35233, USA
J Pediatr 162:587-592.e3. 2013..To report circuit characteristics and survival analysis in children weighing ≤10 kg enrolled in the Prospective Pediatric Continuous Renal Replacement Therapy (ppCRRT) Registry...
Urine biomarkers predict acute kidney injury and mortality in very low birth weight infantsDavid J Askenazi
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
J Pediatr 159:907-12.e1. 2011..To test the hypothesis that noninvasive urinary biomarkers may improve early identification, differentiate causes, and predict outcomes of acute kidney injury (AKI) in very low birth weight subjects...
Renal replacement therapy in critically ill patients receiving extracorporeal membrane oxygenationDavid J Askenazi
Division of Pediatric Nephrology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
Clin J Am Soc Nephrol 7:1328-36. 2012....
Urine biomarkers predict acute kidney injury in newbornsDavid J Askenazi
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
J Pediatr 161:270-5.e1. 2012..To identify urine biomarkers predictive of acute kidney injury (AKI) in infants admitted to level 2 and 3 neonatal intensive care units with birth weight >2000 g and 5-minute Apgar score ≤ 7...
Are we ready for the clinical use of novel acute kidney injury biomarkers?David Askenazi
Pediatrics, University of Alabama at Birmingham, 1600 7th Ave So, ACC 516, Birmingham, AL, 35233, USA
Pediatr Nephrol 27:1423-5. 2012..Large-scale observational multi-center studies are needed to test these biomarkers against hard clinical endpoints. In addition, randomized intervention trials which use biomarkers to define AKI need to be performed...
Baseline values of candidate urine acute kidney injury biomarkers vary by gestational age in premature infantsDavid J Askenazi
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
Pediatr Res 70:302-6. 2011..We conclude that urine values of candidate AKI biomarkers are higher in the most premature infants. These findings should be considered when designing and analyzing biomarker studies in newborn with AKI...
Evaluation and management of critically ill children with acute kidney injuryDavid Askenazi
University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
Curr Opin Pediatr 23:201-7. 2011....
Acute kidney injury and renal replacement therapy independently predict mortality in neonatal and pediatric noncardiac patients on extracorporeal membrane oxygenationDavid J Askenazi
Department of Pediatrics, University of Alabama at Birmingham, School of Public Health, Birmingham, AL, USA
Pediatr Crit Care Med 12:e1-6. 2011..AKI and RRT portend poor outcomes independent of comorbidities and illness severity in several critically ill populations...
Acute kidney injury is independently associated with mortality in very low birthweight infants: a matched case-control analysisDavid J Askenazi
Division of Pediatric Nephrology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
Pediatr Nephrol 24:991-7. 2009..90, 95% CI 1.10-3.27). After confounding variables had been controlled for, AKI was independently associated with mortality in VLBW infants. Further prospective multi-center studies are needed to determine whether this association exists...
Acute kidney injury in critically ill newborns: what do we know? What do we need to learn?David J Askenazi
Division of Pediatric Nephrology, University of Alabama at Birmingham, 1600 7th Ave So, ACC 516, Birmingham, AL, 35233, USA
Pediatr Nephrol 24:265-74. 2009..Early biomarkers of AKI need to be explored in critically ill neonates. Infants with AKI need to be followed for sequelae after AKI...
An unusual case of peritoneal dialysis malfunctionD Askenazi
Department of Pediatrics, Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
Kidney Int 72:524. 2007
Outcomes of children with proliferative lupus nephritis: the role of protocol renal biopsyDavid Askenazi
Department of Pediatrics, University of Alabama at Birmingham, 1600 7th Avenue South, ACC 516, Birmingham, AL, 35233, USA
Pediatr Nephrol 22:981-6. 2007..Those who did not improve are at risk for flares and progression of disease. The tailoring of therapies based on findings from a biopsy after induction may improve outcomes...
3-5 year longitudinal follow-up of pediatric patients after acute renal failureD J Askenazi
Department of Pediatric Nephrology, Baylor College of Medicine, Houston, Texas, USA
Kidney Int 69:184-9. 2006..Patients have high risks of ongoing residual renal injury and death after ARF; therefore, periodic evaluation after the initial insult is necessary...
Pediatric acute kidney injury: the use of the RIFLE criteriaD J Askenazi
Children s Hospital of Alabama, Department of Pediatric Nephrology, University of Alabama, Birmingham, Alabama, USA
Kidney Int 71:963-4. 2007..Standard markers of severity of illness do not identify AKI. Modified RIFLE criteria are shown to identify patients who develop AKI, potentially allowing for early intervention...
