Shahab Asgharzadeh

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Copy number variation signature to predict human ancestry
    Melissa Pronold
    Department of Pediatrics, Children s Hospital Los Angeles and the Saban Research Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    BMC Bioinformatics 13:336. 2012
  2. pmc Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma
    Shahab Asgharzadeh
    Children s Hospital Los Angeles, Los Angeles, CA 90027, USA
    J Clin Oncol 30:3525-32. 2012
  3. ncbi request reprint Prognostic significance of gene expression profiles of metastatic neuroblastomas lacking MYCN gene amplification
    Shahab Asgharzadeh
    Department of Pediatrics, Division of Hematology Oncology, Childrens Hospital Los Angeles and Saban Research Institute, University of Southern California, Los Angeles, CA, USA
    J Natl Cancer Inst 98:1193-203. 2006
  4. pmc Joint estimation of copy number variation and reference intensities on multiple DNA arrays using GADA
    Roger Pique-Regi
    Signal and Image Processing Institute, Ming Hsieh Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, EEB 400, 3740 McClintock Ave, Los Angeles, CA 90089 2564, USA
    Bioinformatics 25:1223-30. 2009
  5. pmc Valpha24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages
    Liping Song
    Division of Hematology Oncology, Department of Pediatrics, University of Southern California Keck School of Medicine, and The Saban Research Institute of Childrens Hospital Los Angeles, Los Angeles, California, USA
    J Clin Invest 119:1524-36. 2009
  6. doi request reprint Intensive induction chemotherapy followed by high dose chemotherapy with autologous hematopoietic progenitor cell rescue in young children newly diagnosed with central nervous system atypical teratoid rhabdoid tumors
    Sharon L Gardner
    Department of Pediatrics, New York University, New York, New York 10016, USA
    Pediatr Blood Cancer 51:235-40. 2008
  7. doi request reprint Membrane-bound TRAIL supplements natural killer cell cytotoxicity against neuroblastoma cells
    Michael A Sheard
    Division of Hematology Oncology, Children s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA
    J Immunother 36:319-29. 2013
  8. pmc Sparse representation and Bayesian detection of genome copy number alterations from microarray data
    Roger Pique-Regi
    Signal and Image Processing Institute, Ming Hsieh Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, EEB 400, 3740 McClintock Ave, Los Angeles, CA 90089 2564, USA
    Bioinformatics 24:309-18. 2008
  9. doi request reprint Bioinformatics for copy number variation data
    Melissa Warden
    Department of Pediatrics and Pathology, Keck School of Medicine, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA
    Methods Mol Biol 719:235-49. 2011
  10. ncbi request reprint Intensive chemotherapy followed by consolidative myeloablative chemotherapy with autologous hematopoietic cell rescue (AuHCR) in young children with newly diagnosed supratentorial primitive neuroectodermal tumors (sPNETs): report of the Head Start I and I
    Jason Fangusaro
    Children s Hospital Los Angeles, Los Angeles, California, USA
    Pediatr Blood Cancer 50:312-8. 2008

Collaborators

Detail Information

Publications13

  1. pmc Copy number variation signature to predict human ancestry
    Melissa Pronold
    Department of Pediatrics, Children s Hospital Los Angeles and the Saban Research Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    BMC Bioinformatics 13:336. 2012
    ..Here we describe a simple and novel approach to locate genome-wide CNVs common to a specific population, using human ancestry as the phenotype...
  2. pmc Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma
    Shahab Asgharzadeh
    Children s Hospital Los Angeles, Los Angeles, CA 90027, USA
    J Clin Oncol 30:3525-32. 2012
    ..In this study, we investigated the hypothesis that expression of genes related to tumor-associated inflammatory cells correlates with the observed differences in survival by age at diagnosis and contributes to a prognostic signature...
  3. ncbi request reprint Prognostic significance of gene expression profiles of metastatic neuroblastomas lacking MYCN gene amplification
    Shahab Asgharzadeh
    Department of Pediatrics, Division of Hematology Oncology, Childrens Hospital Los Angeles and Saban Research Institute, University of Southern California, Los Angeles, CA, USA
    J Natl Cancer Inst 98:1193-203. 2006
    ..We examined whether molecular classification of metastatic neuroblastomas without MYCN gene amplification at diagnosis using gene expression profiling could improve the prediction of risk of disease progression...
  4. pmc Joint estimation of copy number variation and reference intensities on multiple DNA arrays using GADA
    Roger Pique-Regi
    Signal and Image Processing Institute, Ming Hsieh Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, EEB 400, 3740 McClintock Ave, Los Angeles, CA 90089 2564, USA
    Bioinformatics 25:1223-30. 2009
    ..New approaches capable of jointly modeling the copy number and the non-copy number (noise) hybridization effects across multiple samples will potentially lead to more accurate results...
  5. pmc Valpha24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages
    Liping Song
    Division of Hematology Oncology, Department of Pediatrics, University of Southern California Keck School of Medicine, and The Saban Research Institute of Childrens Hospital Los Angeles, Los Angeles, California, USA
    J Clin Invest 119:1524-36. 2009
    ..Thus, killing of TAMs reveals what we believe to be a novel mechanism of NKT antitumor activity that relates to the disease outcome...
  6. doi request reprint Intensive induction chemotherapy followed by high dose chemotherapy with autologous hematopoietic progenitor cell rescue in young children newly diagnosed with central nervous system atypical teratoid rhabdoid tumors
    Sharon L Gardner
    Department of Pediatrics, New York University, New York, New York 10016, USA
    Pediatr Blood Cancer 51:235-40. 2008
    ..Historically, surgery and standard dose chemotherapy have resulted in a median survival of 8.5 months from diagnosis...
  7. doi request reprint Membrane-bound TRAIL supplements natural killer cell cytotoxicity against neuroblastoma cells
    Michael A Sheard
    Division of Hematology Oncology, Children s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA
    J Immunother 36:319-29. 2013
    ..Together, these findings support a role for membrane-bound TRAIL in the cytotoxicity of NK cells against neuroblastoma cells...
  8. pmc Sparse representation and Bayesian detection of genome copy number alterations from microarray data
    Roger Pique-Regi
    Signal and Image Processing Institute, Ming Hsieh Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, EEB 400, 3740 McClintock Ave, Los Angeles, CA 90089 2564, USA
    Bioinformatics 24:309-18. 2008
    ..This article proposes a novel detection technique that exploits the use of piece wise constant (PWC) vectors to represent genome copy number and sparse Bayesian learning (SBL) to detect CNA breakpoints...
  9. doi request reprint Bioinformatics for copy number variation data
    Melissa Warden
    Department of Pediatrics and Pathology, Keck School of Medicine, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA
    Methods Mol Biol 719:235-49. 2011
    ..Here we describe a practical introduction to the copy number variation technology and available analysis methods, and demonstrate the analysis flow on an example case...
  10. ncbi request reprint Intensive chemotherapy followed by consolidative myeloablative chemotherapy with autologous hematopoietic cell rescue (AuHCR) in young children with newly diagnosed supratentorial primitive neuroectodermal tumors (sPNETs): report of the Head Start I and I
    Jason Fangusaro
    Children s Hospital Los Angeles, Los Angeles, California, USA
    Pediatr Blood Cancer 50:312-8. 2008
    ....
  11. pmc Prediction of human functional genetic networks from heterogeneous data using RVM-based ensemble learning
    Chia Chin Wu
    Department of Biomedical Engineering, University of Southern California, Los Angeles, 90089, USA
    Bioinformatics 26:807-13. 2010
    ....
  12. doi request reprint Novel pathways to erythropoiesis induced by dimerization of intracellular C-Mpl in human hematopoietic progenitors
    Chintan Parekh
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095 1732, USA
    Stem Cells 30:697-708. 2012
    ..Ligand-inducible dimerization of intracellular Mpl in human myeloerythroid progenitors induces progenitor expansion and erythropoiesis through molecular mechanisms that are not shared by Tpo stimulation of endogenous Mpl...
  13. pmc Natural killer T cells infiltrate neuroblastomas expressing the chemokine CCL2
    Leonid S Metelitsa
    Department of Pediatrics, Division of Hematology Oncology, MS 57, Childrens Hospital Los Angeles, 4650 Sunset Blvd, Los Angeles, CA 90027, USA
    J Exp Med 199:1213-21. 2004
    ..001). In summary, iNKTs migrate toward neuroblastoma cells in a CCL2-dependent manner, preferentially infiltrating MYCN nonamplified tumors that express CCL2...