Affiliation: University of California
Ascenzi M, Liao V, Lee B, Billi F, Zhou H, Lindsay R, et al
. Parathyroid hormone treatment improves the cortical bone microstructure by improving the distribution of type I collagen in postmenopausal women with osteoporosis. J Bone Miner Res. 2012;27:702-12 pubmed publisher
..75 ± 1.22 to 80.13 ± 6.47, p = 0.001. In conclusion, PTH treatment increases heterogeneity of collagen orientation, a starting point from which to study the reduction in fracture risk when PTH is used to treat osteoporosis. ..
Ascenzi M, Chin J, Lappe J, Recker R. Non-osteoporotic women with low-trauma fracture present altered birefringence in cortical bone. Bone. 2016;84:104-12 pubmed publisher
..Our results evidence the need to investigate, in a larger sample of subjects, the distribution of collagen orientation as a parameter diagnostic of increased fracture risk. ..
Ascenzi M, Lomovtsev A. Collagen orientation patterns in human secondary osteons, quantified in the radial direction by confocal microscopy. J Struct Biol. 2006;153:14-30 pubmed
..Measured patterns complement previous indirect results by different methods and reinforce previously hypothesized differences in lamellar mechanical functions. ..
Ascenzi M, Blanco C, Drayer I, Kim H, Wilson R, Retting K, et al
. Effect of localization, length and orientation of chondrocytic primary cilium on murine growth plate organization. J Theor Biol. 2011;285:147-55 pubmed publisher
..Our mathematically predicted cell division process will need to be observed experimentally to advance the identification of ciliary function in the growth plate...