Maria-Grazia Ascenzi

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint The osteon: the micromechanical unit of compact bone
    Maria Grazia Ascenzi
    UCLA Orthopaedic Hospital Department of Orthopaedic Surgery, University of California at Los Angeles
    Front Biosci (Landmark Ed) 17:1551-81. 2012
  2. doi request reprint Parathyroid hormone treatment improves the cortical bone microstructure by improving the distribution of type I collagen in postmenopausal women with osteoporosis
    Maria Grazia Ascenzi
    UCLA Orthopaedic Hospital Department of Orthopaedic Surgery, University of California at Los Angeles, Los Angeles, CA 90095, USA
    J Bone Miner Res 27:702-12. 2012
  3. ncbi request reprint Mathematical modeling of human secondary osteons
    Maria Grazia Ascenzi
    Department of Orthopaedic Surgery, Biomechanics Research Division, University of California at Los Angeles, Los Angeles, California 90095, USA
    Scanning 26:25-35. 2004
  4. ncbi request reprint Collagen orientation patterns in human secondary osteons, quantified in the radial direction by confocal microscopy
    Maria Grazia Ascenzi
    Department of Orthopaedic Surgery, Biomechanics Research Division, University of California at Los Angeles, USA
    J Struct Biol 153:14-30. 2006
  5. pmc Analysis of the orientation of primary cilia in growth plate cartilage: a mathematical method based on multiphoton microscopical images
    Maria Grazia Ascenzi
    Department of Orthopaedic Surgery, Biomechanics Research Division, University of California, Rehabilitation Bldg 22 69, 1000 Veteran Avenue, Los Angeles, CA 90095, USA
    J Struct Biol 158:293-306. 2007
  6. ncbi request reprint Hysteretic pinching of human secondary osteons subjected to torsion
    Maria Grazia Ascenzi
    Department of Orthopaedic Surgery, Biomechanics Research Division, University of California at Los Angeles, CA, USA
    J Biomech 40:2619-27. 2007
  7. doi request reprint Orientation of collagen at the osteocyte lacunae in human secondary osteons
    Maria Grazia Ascenzi
    UCLA Orthopaedic Hospital Department of Orthopaedic Surgery, Biomechanics Research Division, Rehabilitation Bldg 22 69, 1000 Veteran Avenue, University of California, Los Angeles, CA 90095, USA
    J Biomech 41:3426-35. 2008
  8. doi request reprint Variation of trabecular architecture in proximal femur of postmenopausal women
    Maria Grazia Ascenzi
    UCLA Orthopaedic Hospital Department of Orthopaedic Surgery, Biomechanics Research, University of California at Los Angeles, CA, USA
    J Biomech 44:248-56. 2011
  9. pmc Effect of localization, length and orientation of chondrocytic primary cilium on murine growth plate organization
    Maria Grazia Ascenzi
    Department of Orthopedic Surgery, University of California at Los Angeles, Rehabilitation Building 22 69, 1000 Veteran Avenue, Los Angeles, CA 90095, USA
    J Theor Biol 285:147-55. 2011

Detail Information

Publications9

  1. ncbi request reprint The osteon: the micromechanical unit of compact bone
    Maria Grazia Ascenzi
    UCLA Orthopaedic Hospital Department of Orthopaedic Surgery, University of California at Los Angeles
    Front Biosci (Landmark Ed) 17:1551-81. 2012
    ..Arrangement, distribution and quality of the elementary components may participate in fracture risk. The latest results underline the fundamental role of the orientation of collagen type I and of carbonated hydroxyapatite crystallites...
  2. doi request reprint Parathyroid hormone treatment improves the cortical bone microstructure by improving the distribution of type I collagen in postmenopausal women with osteoporosis
    Maria Grazia Ascenzi
    UCLA Orthopaedic Hospital Department of Orthopaedic Surgery, University of California at Los Angeles, Los Angeles, CA 90095, USA
    J Bone Miner Res 27:702-12. 2012
    ..75 ± 1.22 to 80.13 ± 6.47, p = 0.001. In conclusion, PTH treatment increases heterogeneity of collagen orientation, a starting point from which to study the reduction in fracture risk when PTH is used to treat osteoporosis...
  3. ncbi request reprint Mathematical modeling of human secondary osteons
    Maria Grazia Ascenzi
    Department of Orthopaedic Surgery, Biomechanics Research Division, University of California at Los Angeles, Los Angeles, California 90095, USA
    Scanning 26:25-35. 2004
    ..The approach taken here is of wide application and could be of value in other areas of microscopy such as scanning electron microscopy, microcomputerized tomography scan, and magnetic resonance imaging on cancellous bone structures...
  4. ncbi request reprint Collagen orientation patterns in human secondary osteons, quantified in the radial direction by confocal microscopy
    Maria Grazia Ascenzi
    Department of Orthopaedic Surgery, Biomechanics Research Division, University of California at Los Angeles, USA
    J Struct Biol 153:14-30. 2006
    ..Measured patterns complement previous indirect results by different methods and reinforce previously hypothesized differences in lamellar mechanical functions...
  5. pmc Analysis of the orientation of primary cilia in growth plate cartilage: a mathematical method based on multiphoton microscopical images
    Maria Grazia Ascenzi
    Department of Orthopaedic Surgery, Biomechanics Research Division, University of California, Rehabilitation Bldg 22 69, 1000 Veteran Avenue, Los Angeles, CA 90095, USA
    J Struct Biol 158:293-306. 2007
    ....
  6. ncbi request reprint Hysteretic pinching of human secondary osteons subjected to torsion
    Maria Grazia Ascenzi
    Department of Orthopaedic Surgery, Biomechanics Research Division, University of California at Los Angeles, CA, USA
    J Biomech 40:2619-27. 2007
    ....
  7. doi request reprint Orientation of collagen at the osteocyte lacunae in human secondary osteons
    Maria Grazia Ascenzi
    UCLA Orthopaedic Hospital Department of Orthopaedic Surgery, Biomechanics Research Division, Rehabilitation Bldg 22 69, 1000 Veteran Avenue, University of California, Los Angeles, CA 90095, USA
    J Biomech 41:3426-35. 2008
    ..We further conjecture that collagen orientation diverts propagation of micro-cracks initiating from apices...
  8. doi request reprint Variation of trabecular architecture in proximal femur of postmenopausal women
    Maria Grazia Ascenzi
    UCLA Orthopaedic Hospital Department of Orthopaedic Surgery, Biomechanics Research, University of California at Los Angeles, CA, USA
    J Biomech 44:248-56. 2011
    ..This phenomenon may render the local tissue less able to carry out the expected mechanical function...
  9. pmc Effect of localization, length and orientation of chondrocytic primary cilium on murine growth plate organization
    Maria Grazia Ascenzi
    Department of Orthopedic Surgery, University of California at Los Angeles, Rehabilitation Building 22 69, 1000 Veteran Avenue, Los Angeles, CA 90095, USA
    J Theor Biol 285:147-55. 2011
    ..Our mathematically predicted cell division process will need to be observed experimentally to advance the identification of ciliary function in the growth plate...