Steven E Arnold
Affiliation: University of Pennsylvania
Arnold S, Lucki I, BROOKSHIRE B, Carlson G, Browne C, Kazi H, et al
. High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice. Neurobiol Dis. 2014;67:79-87 pubmed publisher
..These findings indicate that HFD is associated with telencephalic insulin resistance and deleterious effects on synaptic integrity and cognitive behaviors. ..
Arnold S, Louneva N, Cao K, Wang L, Han L, Wolk D, et al
. Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease. Neurobiol Aging. 2013;34:157-68 pubmed publisher
..These data characterize cellular and synaptic features and identify novel biochemical targets that may be associated with resilient cognitive brain aging in the setting of pathological AD. ..
Buchman A, Boyle P, Wilson R, James B, Leurgans S, Arnold S, et al
. Loneliness and the rate of motor decline in old age: the Rush Memory and Aging Project, a community-based cohort study. BMC Geriatr. 2010;10:77 pubmed publisher
..Among community-dwelling older persons, both feeling alone and being alone are associated with more rapid motor decline, underscoring the importance of psychosocial factors and motor decline in old age. ..
Arnold S, Lee E, Moberg P, Stutzbach L, Kazi H, Han L, et al
. Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease. Ann Neurol. 2010;67:462-9 pubmed publisher
..Future work may assess the utility of amyloid-beta and PHFtau measurement in OE as a biomarker for AD. ..
Yarchoan M, Arnold S. Repurposing diabetes drugs for brain insulin resistance in Alzheimer disease. Diabetes. 2014;63:2253-61 pubmed publisher