S E Arnold

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Human fetal hippocampal development: I. Cytoarchitecture, myeloarchitecture, and neuronal morphologic features
    S E Arnold
    Department of Psychiatry and Neurology, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    J Comp Neurol 367:274-92. 1996
  2. ncbi request reprint Human fetal hippocampal development: II. The neuronal cytoskeleton
    S E Arnold
    Department of Psychiatry and Neurology, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    J Comp Neurol 367:293-307. 1996
  3. ncbi request reprint Glial fibrillary acidic protein-immunoreactive astrocytosis in elderly patients with schizophrenia and dementia
    S E Arnold
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Acta Neuropathol 91:269-77. 1996
  4. ncbi request reprint Recent advances in defining the neuropathology of schizophrenia
    S E Arnold
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104 4283, USA
    Acta Neuropathol 92:217-31. 1996
  5. ncbi request reprint Absence of neurodegeneration and neural injury in the cerebral cortex in a sample of elderly patients with schizophrenia
    S E Arnold
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Arch Gen Psychiatry 55:225-32. 1998
  6. ncbi request reprint Quantitative neurohistological features of frontotemporal degeneration
    S E Arnold
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Neurobiol Aging 21:913-9. 2000
  7. pmc Novel CSF biomarkers for frontotemporal lobar degenerations
    W T Hu
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia 19104 4283, USA
    Neurology 75:2079-86. 2010
  8. ncbi request reprint Cellular and molecular neuropathology of the parahippocampal region in schizophrenia
    S E Arnold
    Department of Psychiatry, University of Pennsylvania, Philadelphia 19104, USA
    Ann N Y Acad Sci 911:275-92. 2000
  9. pmc Plasma biomarkers of depressive symptoms in older adults
    S E Arnold
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
    Transl Psychiatry 2:e65. 2012
  10. ncbi request reprint Cellular and molecular neuropathology of the olfactory epithelium and central olfactory pathways in Alzheimer's disease and schizophrenia
    S E Arnold
    Department of Psychiatry, University of Pennsylvania, Philadelphia 19104, USA
    Ann N Y Acad Sci 855:762-75. 1998

Detail Information

Publications20

  1. ncbi request reprint Human fetal hippocampal development: I. Cytoarchitecture, myeloarchitecture, and neuronal morphologic features
    S E Arnold
    Department of Psychiatry and Neurology, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    J Comp Neurol 367:274-92. 1996
    ..These studies delineate normal neuroanatomic development and can be used to understand better the mechanisms underlying human neurodevelopmental and neurodegenerative disorders of the hippocampal formation...
  2. ncbi request reprint Human fetal hippocampal development: II. The neuronal cytoskeleton
    S E Arnold
    Department of Psychiatry and Neurology, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    J Comp Neurol 367:293-307. 1996
    ..These observations have implications for understanding the role of the neuronal cytoskeleton in the developing, mature, and diseased CNS...
  3. ncbi request reprint Glial fibrillary acidic protein-immunoreactive astrocytosis in elderly patients with schizophrenia and dementia
    S E Arnold
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Acta Neuropathol 91:269-77. 1996
    ..In the absence of any diagnostic neuropathological findings in this subgroup, the implications of these observations for the pathogenesis of schizophrenia remain to be determined...
  4. ncbi request reprint Recent advances in defining the neuropathology of schizophrenia
    S E Arnold
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104 4283, USA
    Acta Neuropathol 92:217-31. 1996
    ....
  5. ncbi request reprint Absence of neurodegeneration and neural injury in the cerebral cortex in a sample of elderly patients with schizophrenia
    S E Arnold
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Arch Gen Psychiatry 55:225-32. 1998
    ..However, we hypothesized that relatively small accumulations of age- or disease-related neurodegenerative lesions occurring in an otherwise abnormal brain could result in deterioration in schizophrenia...
  6. ncbi request reprint Quantitative neurohistological features of frontotemporal degeneration
    S E Arnold
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Neurobiol Aging 21:913-9. 2000
    ..The molecular neurodegenerative mechanisms that lead to FTD remain to be elucidated...
  7. pmc Novel CSF biomarkers for frontotemporal lobar degenerations
    W T Hu
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia 19104 4283, USA
    Neurology 75:2079-86. 2010
    ..To identify antemortem CSF diagnostic biomarkers that can potentially distinguish between the 2 main causes of frontotemporal lobar degeneration (FTLD), i.e., FTLD with TDP-43 pathology (FTLD-TDP) and FTLD with tau pathology (FTLD-tau)...
  8. ncbi request reprint Cellular and molecular neuropathology of the parahippocampal region in schizophrenia
    S E Arnold
    Department of Psychiatry, University of Pennsylvania, Philadelphia 19104, USA
    Ann N Y Acad Sci 911:275-92. 2000
    ....
  9. pmc Plasma biomarkers of depressive symptoms in older adults
    S E Arnold
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
    Transl Psychiatry 2:e65. 2012
    ....
  10. ncbi request reprint Cellular and molecular neuropathology of the olfactory epithelium and central olfactory pathways in Alzheimer's disease and schizophrenia
    S E Arnold
    Department of Psychiatry, University of Pennsylvania, Philadelphia 19104, USA
    Ann N Y Acad Sci 855:762-75. 1998
    ..Finally, both the olfactory epithelium and central olfactory pathways represent model systems in which to study the neurobiology of these disorders, which ultimately may yield clues with diagnostic and therapeutic utility...
  11. pmc Protease resistant prion proteins are not present in sporadic "poor outcome" schizophrenia
    S E Arnold
    Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, USA
    J Neurol Neurosurg Psychiatry 66:90-2. 1999
    ..No PrPres was found in the brains of any of the cases, providing evidence against a role for abnormal prion proteins in the pathogenesis of schizophrenia...
  12. ncbi request reprint Reduced olfactory bulb volume in patients with schizophrenia
    B I Turetsky
    Department of Psychiatry, Radiology, and Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Psychiatry 157:828-30. 2000
    ..The authors' goal in this study was to compare the size of olfactory bulbs of patients with schizophrenia and those of healthy subjects...
  13. ncbi request reprint Reduced dorsal and orbital prefrontal gray matter volumes in schizophrenia
    R E Gur
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Arch Gen Psychiatry 57:761-8. 2000
    ..Inconsistent reports may relate to variable methods and small samples. We attempted to resolve volume differences within sectors of the prefrontal lobe in a large sample, relating volumes to clinical and neurocognitive features...
  14. ncbi request reprint Cognitive impairment and functional status in elderly institutionalized patients with schizophrenia
    M M Kurtz
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Int J Geriatr Psychiatry 16:631-8. 2001
    ..The relationship of cognitive impairment to functional status in older adults with schizophrenia was investigated...
  15. ncbi request reprint Challenges, status, and opportunities for studying developmental neuropathology in adult schizophrenia
    S E Arnold
    Center for Neurobiology and Behavior, University of Pennsylvania, Philadelphia 19104, USA
    Schizophr Bull 27:395-416. 2001
    ....
  16. ncbi request reprint Novel method to quantify neuropil threads in brains from elders with or without cognitive impairment
    T W Mitchell
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Histochem Cytochem 48:1627-38. 2000
    ..On the basis of data presented here using this novel strategy, we conclude that this quantitative imaging technique will facilitate efforts to determine the behavioral correlations of neuritic lesions in AD and other brain disorders...
  17. ncbi request reprint A comparative volumetric analysis of the prefrontal cortex in human and baboon MRI
    T McBride
    Brain Behavior Laboratory, Department of Psychiatry, The University of Pennsylvania, Philadelphia, PA 19104, USA
    Brain Behav Evol 54:159-66. 1999
    ..On the other hand, the small magnitude of the difference might underlie similarities between the species and should encourage a search for other structures that are disproportionately larger in humans...
  18. ncbi request reprint The medial temporal lobe in schizophrenia
    S E Arnold
    Department of Psychiatry, University of Pennsylvania, Philadelphia 19104, USA
    J Neuropsychiatry Clin Neurosci 9:460-70. 1997
    ..These findings appear most consistent with models of aberrant development of medial temporal lobe structures in schizophrenia...
  19. ncbi request reprint Inositol 1,4,5-trisphosphate receptor expression in odontoblast cells
    G Smutzer
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Biochim Biophys Acta 1358:221-8. 1997
    ..These findings also suggest that inositol 1,4,5-trisphosphate receptor/channels regulate calcium flux in odontoblasts during mineralization of dentin, or in growth and differentiation of incisor tissue...
  20. ncbi request reprint Inositol 1,4,5-trisphosphate receptor expression in mammalian olfactory tissue
    G Smutzer
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Brain Res Mol Brain Res 44:347-54. 1997
    ..These results demonstrate the co-expression of multiple IP3 receptor subtypes in olfactory cells, and suggest multiple functions for IP3 receptors in this tissue...