Affiliation: University of California
- Reduced exercise tolerance and pulmonary capillary recruitment with remote secondhand smoke exposureMehrdad Arjomandi
University of California San Francisco Flight Attendants Medical Research Institute Center of Excellence, San Francisco, California, United States of America
PLoS ONE 7:e34393. 2012..We previously showed never-smoking pre-ban FAs to have reduced diffusing capacity (Dco) at rest...
- Is there an association between lifetime cumulative exposure and acute pulmonary responses to ozone?Mehrdad Arjomandi
Lung Biology Center, University of California, San Francisco, California 94143 0845, USA
J Occup Environ Med 50:341-9. 2008..To investigate the potential effects of lifetime cumulative ozone (O3) exposure on acute pulmonary responses to O3...
- Secreted osteopontin is highly polymerized in human airways and fragmented in asthmatic airway secretionsMehrdad Arjomandi
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 6:e25678. 2011..OPN undergoes extensive post-translational modifications, including polymerization and proteolytic fragmentation, which alters its biologic activity. Recent studies suggest that OPN may contribute to the pathogenesis of asthma...
- Pulmonary function abnormalities in never-smoking flight attendants exposed to secondhand tobacco smoke in the aircraft cabinMehrdad Arjomandi
Center of Excellence, Department of Medicine, Pulmonary and Critical Care Division, University of California, San Francisco, CA 94143 0111, USA
J Occup Environ Med 51:639-46. 2009..To determine whether the flight attendants who were exposed to secondhand tobacco smoke in the aircraft cabin have abnormal pulmonary function...
- Sputum induction and bronchoscopy for assessment of ozone-induced airway inflammation in asthmaMehrdad Arjomandi
Lung Biology Center, Northern California Center for Occupational and Environmental Health, and San Francisco General Hospital, University of California San Francisco, Box 0843, San Francisco, CA 94143 0843, USA
Chest 128:416-23. 2005..However, the comparability of these methods (BAL and SI) after experimental treatment has not been investigated in a head-to-head controlled trial...
- Effects of chronic and acute ozone exposure on lipid peroxidation and antioxidant capacity in healthy young adultsConnie Chen
Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA 94720 7360, USA
Environ Health Perspect 115:1732-7. 2007..There is growing evidence for the role of oxidative damage in chronic diseases. Although ozone (O3) is an oxidant pollutant to which many people are exposed, few studies have examined whether O3 induces oxidative stress in humans...
- Effects of exercise on systemic inflammatory, coagulatory, and cardiac autonomic parameters in an inhalational exposure studyAneesh Donde
Human Exposure Laboratory, Division of Occupational and Environmental Medicine, University of California San Francisco, San Francisco, CA, USA
J Occup Environ Med 54:466-70. 2012..Intermittent moderate-intensity exercise is used in human inhalational exposure studies to increase the effective dose of air pollutants...
- Effects of nitrogen dioxide on allergic airway responses in subjects with asthmaAllyson Witten
Lung Biology Center and Division of Occupational and Environmental Medicine, University of California, San Francisco, California 94143 0843, USA
J Occup Environ Med 47:1250-9. 2005..We sought to determine whether nitrogen dioxide (NO2) can enhance airway inflammation after allergen challenge in asthmatic subjects...
- Cytogenetic damage in buccal epithelia and peripheral lymphocytes of young healthy individuals exposed to ozoneConnie Chen
Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, 94720 7360, USA
Mutagenesis 21:131-7. 2006..p.b. O(3). This cytogenetic evidence, along with recent studies linking O(3) exposure to elevated lung cancer risk and mortality, suggest potential public health implications from exposures to high oxidant environments...
- Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contractionMakoto Kudo
Lung Biology Center, University of California, San Francisco, CA 94143, USA
Proc Natl Acad Sci U S A 110:660-5. 2013..These data indicate that Mfge8 binding to integrin receptors on ASM opposes the effect of allergic inflammation on RhoA activity and identify a pathway for specific inhibition of ASM hypercontractility in asthma...
- Repeated exposure to ozone increases alveolar macrophage recruitment into asthmatic airwaysMehrdad Arjomandi
Lung Biology Center, Department of Medicine, University of California, San Francisco, CA 94143, USA
Am J Respir Crit Care Med 172:427-32. 2005....
- PAI-1 is an essential component of the pulmonary host response during Pseudomonas aeruginosa pneumonia in miceArnaud Goolaerts
Department of Anesthesiology, Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, USA
Thorax 66:788-96. 2011..However, whether PAI-1 plays a pathogenic role in the breakdown of the alveolar-capillary barrier caused by P aeruginosa is unknown...
- Low prevalence of chronic beryllium disease among workers at a nuclear weapons research and development facilityMehrdad Arjomandi
Department of Medicine, University of California, San Francisco, CA, USA
J Occup Environ Med 52:647-52. 2010..To study the prevalence of beryllium sensitization (BeS) and chronic beryllium disease (CBD) in a cohort of workers from a nuclear weapons research and development facility...