Robert Aris

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi request reprint Management of osteoporosis in adults with cystic fibrosis
    Travis M Hecker
    Division of Pulmonary and Critical Care Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7524, USA
    Drugs 64:133-47. 2004
  2. pmc Vitamin d deficiency in cystic fibrosis
    William B Hall
    Division of Pulmonary and Critical Care Medicine and the School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Int J Endocrinol 2010:218691. 2010
  3. ncbi request reprint Treatment of bone disease in cystic fibrosis
    Robert Aris
    Division of Pulmonary Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Curr Opin Pulm Med 10:524-30. 2004
  4. ncbi request reprint Growth factor upregulation during obliterative bronchiolitis in the mouse model
    Robert M Aris
    Division of Pulmonary Medicine, Department of Medicine, 420 Burnett Womack Building, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7524, USA
    Am J Respir Crit Care Med 166:417-22. 2002
  5. ncbi request reprint Guide to bone health and disease in cystic fibrosis
    Robert M Aris
    CB 7020, 4131 Bioinformatics, University of North Carolina, Chapel Hill, North Carolina 27599 7524, USA
    J Clin Endocrinol Metab 90:1888-96. 2005
  6. ncbi request reprint Altered calcium homeostasis in adults with cystic fibrosis
    R M Aris
    Division of Pulmonary Medicine, University of North Carolina, Chapel Hill 27599 7524, USA
    Osteoporos Int 10:102-8. 1999
  7. ncbi request reprint Abnormal bone turnover in cystic fibrosis adults
    R M Aris
    Divisions of Pulmonary Medicine, The University of North Carolina at Chapel Hill, 27599 7524, USA
    Osteoporos Int 13:151-7. 2002
  8. ncbi request reprint Lung transplantation for cystic fibrosis patients with Burkholderia cepacia complex. Survival linked to genomovar type
    R M Aris
    Division of Pulmonary Medicine, The Department of Medicine, The University of North Carolina at Chapel Hill School of Medicine, NC 27599 7524, USA
    Am J Respir Crit Care Med 164:2102-6. 2001
  9. ncbi request reprint Adverse alterations in bone metabolism are associated with lung infection in adults with cystic fibrosis
    R M Aris
    Divisions of Pulmonary Medicine and Endocrinology, the Departments of Medicine and Orthopedics, and School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7524, USA
    Am J Respir Crit Care Med 162:1674-8. 2000
  10. ncbi request reprint Efficacy of pamidronate for osteoporosis in patients with cystic fibrosis following lung transplantation
    R M Aris
    Divisions of Pulmonary Medicine and Endocrinology, and the Departments of Medicine, Orthopedics, and Radiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Am J Respir Crit Care Med 162:941-6. 2000

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Management of osteoporosis in adults with cystic fibrosis
    Travis M Hecker
    Division of Pulmonary and Critical Care Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7524, USA
    Drugs 64:133-47. 2004
    ..Teriparatide may offer a new avenue for treating bone disease in CF since many patients may have poor bone formation as well as accelerated bone breakdown. Numerous clinical trials are underway to optimise treatment of CF osteoporosis...
  2. pmc Vitamin d deficiency in cystic fibrosis
    William B Hall
    Division of Pulmonary and Critical Care Medicine and the School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Int J Endocrinol 2010:218691. 2010
    ..More research is needed to determine optimal supplementation goals and strategies...
  3. ncbi request reprint Treatment of bone disease in cystic fibrosis
    Robert Aris
    Division of Pulmonary Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Curr Opin Pulm Med 10:524-30. 2004
    ..Bone disease in CF has not been previously reviewed in this journal. Therefore, this review will give a brief overview of bone disease in CF and then concentrate on treatment options...
  4. ncbi request reprint Growth factor upregulation during obliterative bronchiolitis in the mouse model
    Robert M Aris
    Division of Pulmonary Medicine, Department of Medicine, 420 Burnett Womack Building, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7524, USA
    Am J Respir Crit Care Med 166:417-22. 2002
    ..037) in this model. We conclude that increased expression of a large number of growth factors occurs during OB in this model. Growth factor blockade (in particular with regard to TNF-alpha) may be useful in ameliorating OB in this model...
  5. ncbi request reprint Guide to bone health and disease in cystic fibrosis
    Robert M Aris
    CB 7020, 4131 Bioinformatics, University of North Carolina, Chapel Hill, North Carolina 27599 7524, USA
    J Clin Endocrinol Metab 90:1888-96. 2005
    ..The goal of this conference was to develop practice guidelines for optimizing bone health in patients with CF...
  6. ncbi request reprint Altered calcium homeostasis in adults with cystic fibrosis
    R M Aris
    Division of Pulmonary Medicine, University of North Carolina, Chapel Hill 27599 7524, USA
    Osteoporos Int 10:102-8. 1999
    ..03), suggesting mild secondary hyperparathyroidism. Altered calcium homeostasis is likely to be a factor in the development of bone disease in CF patients...
  7. ncbi request reprint Abnormal bone turnover in cystic fibrosis adults
    R M Aris
    Divisions of Pulmonary Medicine, The University of North Carolina at Chapel Hill, 27599 7524, USA
    Osteoporos Int 13:151-7. 2002
    ..These results indicate that adults with CF have increased bone resorption with little change in bone formation. Medications that decrease bone resorption or improve calcium homeostasis may be effective therapies for CF bone disease...
  8. ncbi request reprint Lung transplantation for cystic fibrosis patients with Burkholderia cepacia complex. Survival linked to genomovar type
    R M Aris
    Division of Pulmonary Medicine, The Department of Medicine, The University of North Carolina at Chapel Hill School of Medicine, NC 27599 7524, USA
    Am J Respir Crit Care Med 164:2102-6. 2001
    ..These results warrant a multicenter analysis of B. cepacia complex-infected patients with genomovar-typing to confirm that genomovar III patients are at highest risk for post-transplant complications...
  9. ncbi request reprint Adverse alterations in bone metabolism are associated with lung infection in adults with cystic fibrosis
    R M Aris
    Divisions of Pulmonary Medicine and Endocrinology, the Departments of Medicine and Orthopedics, and School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7524, USA
    Am J Respir Crit Care Med 162:1674-8. 2000
    ..These results provide insights into the impact of systemic inflammation on bone health, and suggest novel mechanisms for bone disease in CF...
  10. ncbi request reprint Efficacy of pamidronate for osteoporosis in patients with cystic fibrosis following lung transplantation
    R M Aris
    Divisions of Pulmonary Medicine and Endocrinology, and the Departments of Medicine, Orthopedics, and Radiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Am J Respir Crit Care Med 162:941-6. 2000
    ....
  11. ncbi request reprint Efficacy of alendronate in adults with cystic fibrosis with low bone density
    Robert M Aris
    Division of Pulmonary Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Am J Respir Crit Care Med 169:77-82. 2004
    ..Alendronate was more effective than placebo in improving spine and femur bone mineral density and is a promising agent for the long-term prevention and management of bone disease in patients with CF...
  12. ncbi request reprint PX3.102, a novel chinese herb extract, diminishes chronic airway allograft rejection
    Worakij Chalermskulrat
    Lung Transplantation Program and Cystic Fibrosis Pulmonary Research and Treatment Center, Division of Pulmonary Disease and Critical Care Medicine, University of North Carolina, School of Medicine, Chapel Hill, NC 27599, USA
    Transplantation 78:158-61. 2004
    ..In conclusion, PX3.102, a promising and potent immunosuppressant, although exhibiting toxicity to airway epithelial cells at high doses, is effective in inhibiting chronic airway allograft rejection...
  13. ncbi request reprint Hierarchical contributions of allorecognition pathways in chronic lung rejection
    Worakij Chalermskulrat
    Division of Pulmonary Disease and Critical Care Medicine, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA
    Am J Respir Crit Care Med 167:999-1007. 2003
    ..In addition, these results suggest that MHC class I molecules are the principal alloantigens in the mouse heterotopic tracheal model of obliterative bronchiolitis...
  14. ncbi request reprint Obliterative bronchiolitis or chronic lung allograft rejection: a basic science review
    Isabel P Neuringer
    Division of Pulmonary and Critical Care Medicine and Cystic Fibrosis Pulmonary Research and Treatment Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    J Heart Lung Transplant 24:3-19. 2005
  15. ncbi request reprint Managing complications following lung transplantation
    Isabel P Neuringer
    Division of Pulmonary and Critical Care Medicine and the Cystic Fibrosis Pulmonary Research and Treatment Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7524, USA
    Expert Rev Respir Med 3:403-23. 2009
    ....
  16. ncbi request reprint High incidence of gastric bezoars in cystic fibrosis patients after lung transplantation
    Evan S Dellon
    Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7080, USA
    Transplantation 81:1141-6. 2006
    ..The aim of this study is to evaluate the incidence of gastric bezoars after lung transplantation and identify associated risk factors...
  17. ncbi request reprint Calcineurin inhibitor effects on growth and phenotype of human airway epithelial cells in vitro
    Isabel P Neuringer
    Division of Pulmonary and Critical Care Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Am J Transplant 5:2660-70. 2005
    ....
  18. ncbi request reprint C-C chemokine receptor 5 on stromal cells promotes pulmonary metastasis
    Hendrik W van Deventer
    Division of Hematology Oncology, Department of Medicine, University of North Carolina at Chapel Hill, Room 3009, Old Clinic Building, NC 27599, USA
    Cancer Res 65:3374-9. 2005
    ..0; P < 0.05). These results show for the first time that CCR5 expression on stromal and not hematopoietic cells contributes to tumor metastasis. Therefore, recently developed CCR5 inhibitors may have a novel benefit in cancer therapy...
  19. ncbi request reprint Epithelial kinetics in mouse heterotopic tracheal allografts
    Isabel P Neuringer
    Division of Pulmonary and Critical Care Medicine, Cystic Fibrosis Pulmonary Research and Treatment Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Am J Transplant 2:410-9. 2002
    ....
  20. doi request reprint Genetics of cystic fibrosis
    Sherstin T Lommatzsch
    Division of Pulmonary and Critical Care Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    Semin Respir Crit Care Med 30:531-8. 2009
    ..Further, it has improved understanding of the mechanism behind seemingly organ-specific manifestations of CF, such as congenital bilateral absence of the vas deferens (CBVAD)...
  21. ncbi request reprint Human leukocyte antigen mismatches predispose to the severity of bronchiolitis obliterans syndrome after lung transplantation
    Worakij Chalermskulrat
    Division of Pulmonary Diseases and Critical Care Medicine, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA
    Chest 123:1825-31. 2003
    ..Bronchiolitis obliterans syndrome (BOS), defined as a staged decline in pulmonary function, is the clinical correlate of OB...
  22. doi request reprint 'Old' bones in young bodies: the tale of cystic fibrosis
    Amy A Sparks
    Division of Pulmonary and Critical Care Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Curr Opin Endocrinol Diabetes Obes 16:407-14. 2009
    ..Approximately, 60 000 individuals are currently living with CF in North America and Europe, almost half of whom are adults...
  23. doi request reprint Post-transplantation lymphoproliferative disease: Epstein-Barr virus DNA levels, HLA-A3, and survival
    Stephen A Wheless
    The School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Am J Respir Crit Care Med 178:1060-5. 2008
    ..Elevation in Epstein-Barr virus (EBV) circulating DNA has been proposed as a marker for development of post-transplant lymphoproliferative disease (PTLD), but few published data exist in the study of lung-transplant recipients...
  24. ncbi request reprint Burkholderia gladioli: five year experience in a cystic fibrosis and lung transplantation center
    Marcus P Kennedy
    Department of Pulmonary Medicine, Unit 403, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    J Cyst Fibros 6:267-73. 2007
    ..The impact of infection with Burkholderia gladioli in cystic fibrosis, other chronic airway diseases and immunosuppressed patients is unknown...
  25. pmc Six-year molecular analysis of Burkholderia cepacia complex isolates among cystic fibrosis patients at a referral center for lung transplantation
    David G Heath
    Clinical Microbiology Immunology Laboratories, University of North Carolina Hospitals, Chapel Hill 27514, USA
    J Clin Microbiol 40:1188-93. 2002
    ..These data suggest that CF patients infected with B. cepacia complex and referred for lung transplantation evaluation were not a major source of B. cepacia complex strains that infected our resident CF clinic population...
  26. ncbi request reprint Carboxylated osteocalcin levels in cystic fibrosis
    Robert M Aris
    Am J Respir Crit Care Med 168:1129. 2003