Research Topics
| D B ArciniegasSummaryAffiliation: University of Colorado Health Sciences Center Country: USA Publications
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Detail Information
Publications
Quetiapine for mania due to traumatic brain injuryTimothy J Oster
Brain Injury Rehabilitation Unit, HealthONE Spalding Rehabilitation Hospital, Aurora, CO, USA
CNS Spectr 12:764-9. 2007..Possible mechanisms of action are discussed and the need for additional investigation of quetiapine for posttraumatic mania is highlighted...
Hippocampus volume loss due to chronic heavy drinkingThomas P Beresford
Mental Health Service, Department of Veterans Affairs Medical Center, University of Colorado School of Medicine, 1055 Clermont Street, Denver, CO 80220, USA
Alcohol Clin Exp Res 30:1866-70. 2006..Our prior work hypothesized significantly lowered total hippocampus volumes in heavy chronically drinking alcohol-dependent (AD) subjects compared with light-drinking nondependent control subjects matched for age and gender...
Neuropsychological patterns in systemic lupus erythematosus patients with depressionElizabeth Kozora
Department of Medicine, National Jewish Medical and Research Center, 1400 Jackson St, Denver, CO 80206, USA
Arthritis Res Ther 9:R48. 2007..Overall, the magnitude and pattern of cognitive impairment in Depressed-SLE patients cannot be explained by depression alone...
Reduced hippocampal volume in association with p50 nonsuppression following traumatic brain injuryD B Arciniegas
Research, Radiology, and Psychiatric Services, Denver Veterans Affairs Medical Center, CO, USA
J Neuropsychiatry Clin Neurosci 13:213-21. 2001..Findings support the hypothesis that hippocampal injury underlies P50 nonsuppression post TBI and suggest that such structural abnormalities may be observed even in "mildly" injured persons...
New-onset bipolar disorder in late life: a case of mistaken identityDavid B Arciniegas
Neuropsychiatry Service, Department of Psychiatry, University of Colorado School of Medicine, Campus Box C268-25, 4200 East Ninth Ave, Denver, CO 80262, USA
Am J Psychiatry 163:198-203. 2006
Treatment of pathologic laughing and cryingHal S Wortzel
David B Arciniegas, MD Brain Injury Rehabilitation Unit, HealthONE Spalding Rehabilitation Hospital, Aurora, CO 80011, USA
Curr Treat Options Neurol 9:371-80. 2007..Education and supportive therapy may help patients and families mitigate the social isolation and embarrassment that PLC episodes frequently produce...
Neurological signs and cognitive performance distinguish between adolescents with and without psychosisDavid B Arciniegas
Neuropsychiatry Service, University of Colorado School of Medicine, Campus Box C268 25, 4200 East Ninth Avenue, Denver, CO 80262, USA
J Neuropsychiatry Clin Neurosci 19:266-73. 2007..There were no relationships between medication status and either NES or IQ scores. These results support a broadly conceived neurodevelopmental formulation of adolescent psychotic disorders...
Pharmacotherapy of posttraumatic cognitive impairmentsDavid B Arciniegas
Brain Injury Rehabilitation Unit, HealthONE Spalding Rehabilitation Hospital, Aurora, CO, USA
Behav Neurol 17:25-42. 2006..Practical considerations regarding the use of pharmacotherapies for posttraumatic cognitive impairments are offered, and the need for additional research in this area is highlighted...
The differential diagnosis of pseudobulbar affect (PBA). Distinguishing PBA among disorders of mood and affect. Proceedings of a roundtable meetingDavid B Arciniegas
Neuropsychiatry Service, Department of Psychiatry, University of Colorado School of Medicine, Denver, Colorado 80211, USA
CNS Spectr 10:1-14; quiz 15-6. 2005..The material presented in this monograph will help clinicians better recognize, diagnose, and treat PBA, and will form a foundation for understanding and interpreting future studies of this condition...
Core curriculum for training in behavioral neurology & neuropsychiatryDavid B Arciniegas
University of Colorado School of Medicine, Department of Psychiatry, Denver, Colorado 80262, USA
J Neuropsychiatry Clin Neurosci 18:6-13. 2006..Finally, a core curriculum for fellowship training in Behavioral Neurology & Neuropsychiatry developed by SBCN and the ANPA is presented...
Viral encephalitis: neuropsychiatric and neurobehavioral aspectsDavid B Arciniegas
Neuropsychiatry Service, Campus Box C268 25, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
Curr Psychiatry Rep 6:372-9. 2004..The current and future role of psychiatrists and neuropsychiatrists in the care and study of individuals with these conditions will be discussed...
The cholinergic hypothesis of cognitive impairment caused by traumatic brain injuryDavid B Arciniegas
Brain Injury Rehabilitation Unit, Spalding Rehabilitation Hospital, Aurora, CO 80011, USA
Curr Psychiatry Rep 5:391-9. 2003..Finally, future directions for investigation of the cholinergic hypothesis and possible clinical applications of this information are discussed...
Psychosis following traumatic brain injuryDavid B Arciniegas
Neuropsychiatry Service, Department of Psychiatry, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Int Rev Psychiatry 15:328-40. 2003....
Applications of the P50 evoked response to the evaluation of cognitive impairments after traumatic brain injuryDavid B Arciniegas
Neuropsychiatry Service, Department of Psychiatry, University of Colorado School of Medicine, Campus Box C28 68, 4200 East Ninth Avenue, Denver, CO 80262, USA
Phys Med Rehabil Clin N Am 15:177-203, viii. 2004..Finally, possible clinical applications and limitations of the P50 ERP in the study, evaluation, and treatment of patients with cognitive impairments after TBI are offered...
Immune function and brain abnormalities in patients with systemic lupus erythematosus without overt neuropsychiatric manifestationsE Kozora
National Jewish Health, Denver, Colorado 80206, USA
Lupus 21:402-11. 2012..This study examined the relationship between immune, cognitive and neuroimaging assessments in subjects with systemic lupus erythematosus (SLE) without histories of overt neuropsychiatric (NP) disorders...
Cognition, MRS neurometabolites, and MRI volumetrics in non-neuropsychiatric systemic lupus erythematosus: preliminary dataElizabeth Kozora
National Jewish Medical and Research Center, Denver, Colorado 80206, USA
Cogn Behav Neurol 18:159-62. 2005..To correlate cognitive dysfunction with structural and neurometabolic brain findings in patients with non-neuropsychiatric systemic lupus erythematosus (non-NPSLE)...
Depression and cognitive complaints following mild traumatic brain injuryJonathan M Silver
Department of Psychiatry, New York University, New Yourk, NY, USA
Am J Psychiatry 166:653-61. 2009..This article discusses the clinical approach to treating an individual with depression and cognitive complaints following mild TBI. Recommendations regarding the diagnosis, evaluation, and treatment of these problems are offered...
Cognitive and neurologic status in patients with systemic lupus erythematosus without major neuropsychiatric syndromesElizabeth Kozora
National Jewish Medical and Research Center and University of Colorado Denver Health Sciences Center, Denver, Colorado 80206, USA
Arthritis Rheum 59:1639-46. 2008..To examine neuropsychological and neurologic functioning in systemic lupus erythematosus (SLE) patients without histories of overt neuropsychiatric disorders (non-NPSLE patients)...
Subtle neurological signs predict the severity of subacute cognitive and functional impairments after traumatic brain injuryHal S Wortzel
Brain Injury Rehabilitation Unit, HealthONE Spalding Rehabilitation Hospital, in Aurora, CO, USA
J Neuropsychiatry Clin Neurosci 21:463-6. 2009....
Memory impairment associated with neurometabolic abnormalities of the hippocampus in patients with non-neuropsychiatric systemic lupus erythematosusE Kozora
1Department of Medicine, National Jewish Health, Denver, CO 80206, USA
Lupus 20:598-606. 2011..This study examined hippocampal volumes and neurometabolic alterations in relation to memory function in SLE patients without a history of neuropsychiatric syndromes (nonNPSLE)...
Colorado surveillance program for chronic wasting disease transmission to humans: lessons from 2 highly suspicious but negative casesC Alan Anderson
Department of Neurology, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Arch Neurol 64:439-41. 2007..To describe 2 patients with rapidly progressive dementia and risk factors for exposure to chronic wasting disease (CWD) in whom extensive testing negated the possible transmission of CWD. Design/..
Performance on the Mini-Mental State Examination and Mattis Dementia Rating Scale among older American IndiansLori L Jervis
American Indian and Alaska Native Programs, Department of Psychiatry, University of Colorado at Denver and Health Sciences Center School of Medicine, Denver, CO, USA
J Neuropsychiatry Clin Neurosci 19:173-8. 2007..Complex relationships were found between gender, health conditions (with possible effects on cognitive functioning), and MMSE and MDRS scores. The authors discuss implications and future directions...
The genetics of very early onset Alzheimer diseaseChristopher M Filley
Department of Neurology, University of Colorado School of Medicine, Denver, CO, USA
Cogn Behav Neurol 20:149-56. 2007..This study was undertaken to clarify the genetics of very early onset Alzheimer disease (VEOAD), defined as AD beginning before age 35...
Amnesia and crime: a neuropsychiatric responseHal S Wortzel
Department of Psychiatry, University of Colorado School of Medicine, 4200 East 9th Avenue, Denver, CO 80262
J Am Acad Psychiatry Law 36:218-23. 2008..Resources on which to build a neuropsychiatric foundation for forensic psychiatric opinions on memory impairment surrounding criminal behavior are offered...
Forensic applications of cerebral single photon emission computed tomography in mild traumatic brain injuryHal S Wortzel
Veterans Integrated Service Network 19 Mental Illness Research, Education, and Clinical Care VISN 19 MIRECC, Denver Veteran s Affairs Medical Center, Denver, CO, USA
J Am Acad Psychiatry Law 36:310-22. 2008....
White matter microstructure and cognition in non-neuropsychiatric systemic lupus erythematosusChristopher M Filley
Department of Neurology, University of Colorado Denver School of Medicine, Denver, CO, USA
Cogn Behav Neurol 22:38-44. 2009..This study examined white matter (WM) structural and metabolic alterations in relation to cognition in patients with non-neuropsychiatric systemic lupus erythematosus (non-NPSLE)...
Comparison of the O-Log and GOAT as measures of posttraumatic amnesiaKimberly L Frey
Brain Injury Rehabilitation Unit, HealthONE Spalding Rehabilitation Hospital, Aurora, Colorado 80011, USA
Brain Inj 21:513-20. 2007..To compare PTA severity and duration assessments made by Orientation Log (O-Log) and the Galveston Orientation and Amnesia Test (GOAT) and the relationship of data yielded by these assessments to rehabilitation outcomes...
Neurosurgical interventions for neuropsychiatric syndromesC Alan Anderson
Neurology B 182, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
Curr Psychiatry Rep 6:355-63. 2004..Lastly, a perspective on the current and future role of psychosurgery for the treatment of mental illnesses will be discussed...
Treatment of acute ischemic stroke: does it impact neuropsychiatric outcome?C Alan Anderson
Neurology B 182, University of Colorado Health Sciences Center, 4200 E 9th Avenue, Denver, CO, USA
J Neuropsychiatry Clin Neurosci 17:486-8. 2005..Further studies are needed to determine the potential benefits of acute stroke treatment on both poststroke neuropsychiatric symptoms and the relationship between such symptoms and stroke outcome...
Predictors of cognitive decline following coronary artery bypass graft surgeryP Michael Ho
Denver Veterans Affairs Medical Center, Denver, Colorado, USA
Ann Thorac Surg 77:597-603; discussion 603. 2004..Our objectives were to identify patient-related risk factors, processes of care, and the occurrence of any perioperative complications associated with cognitive decline...
Hypercortisolism in alcohol dependence and its relation to hippocampal volume lossThomas P Beresford
Mental Health Service, Department of Veterans Affairs Medical Center, 1055 Clermont Street 116, Denver, Colorado 80220 0116, USA
J Stud Alcohol 67:861-7. 2006....
Treatment of depression following traumatic brain injuryBenjamin S Alderfer
Brain Injury Rehabilitation Unit, HealthONE Spalding Rehabilitation Hospital, Aurora, Colorado, USA
J Head Trauma Rehabil 20:544-62. 2005..Finally, psychosocial interventions relevant to the care of persons with posttraumatic depression are presented...
Initial evaluations for multiple sclerosis in a university multiple sclerosis center: outcomes and role of magnetic resonance imaging in referralMario J Carmosino
University of Colorado Multiple Sclerosis Center, University of Colorado School of Medicine, Denver, 80262, USA
Arch Neurol 62:585-90. 2005..With respect to the diagnosis of MS, greater training of primary care professionals, neurologists, and radiologists is necessary...
Amantadine for neurobehavioural deficits following delayed post-hypoxic encephalopathyDavid B Arciniegas
Brain Injury Rehabilitation Unit, Spalding Rehabilitation Hospital, Aurora, CO, USA
Brain Inj 18:1309-18. 2004..A brief review of the literature regarding this condition, its treatment and suggestions for further study are presented...
The differential diagnosis of Axis I psychopathology presenting to a university-based multiple sclerosis clinicK M Brousseau
VISN 19 MIRECC Mental Illness Research Educational Clinical Center, Veteran s Affairs Medical Center, Denver, CO 80220, USA
Mult Scler 13:749-53. 2007..Accurate identification and diagnosis of psychiatric conditions producing pseudoneurological or non-specific somatic symptoms is necessary for both treatment and medico-economic reasons...
Neurobehavioral management of traumatic brain injury in the critical care settingDavid B Arciniegas
Brain Injury Rehabilitation Unit, HealthONE Spalding Rehabilitation Hospital, Aurora, CO 80011, USA
Crit Care Clin 24:737-65, viii. 2008..Recommendations regarding evaluation and management of posttraumatic neurobehavioral problems in the critical care setting are offered...
Constraint-induced movement therapy after stroke: efficacy for patients with minimal upper-extremity motor abilityNancy M Bonifer
HealthONE Spalding Rehabilitation Hospital, Aurora, CO, USA
Arch Phys Med Rehabil 86:1867-73. 2005..To examine the effects of constraint-induced movement therapy (CIMT) on chronic moderate-to-severe upper-extremity motor impairment after stroke...
A clinical overview of pseudobulbar affectDavid B Arciniegas
University of Colorado Health Sciences Center, Denver, Colorado, USA
Am J Geriatr Pharmacother 3:4-8; quiz 16-7. 2005
When cognitive evaluation does not disclose a neurologic disorder: experience of a university behavioral neurology clinicMeredith C Kenfield
Department of Neurology, University of Colorado Denver School of Medicine, Aurora, CO, USA
Cogn Behav Neurol 23:112-8. 2010..We examined clinical features, referral patterns, and diagnostic outcome of patients receiving cognitive evaluation in a behavioral neurology clinic who had no neurologic disorder...
Pathophysiology of involuntary emotional expression disorderPeter V Rabins
Division of Geriatric and Neuropsychiatry, Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA
CNS Spectr 12:17-22. 2007..Pharmacologic interventions targeting the neurochemical modulators of the emotional expression systems may afford opportunities for symptom control among persons affected by this disorder...
Constraint-induced therapy for moderate chronic upper extremity impairment after strokeN M Bonifer
Spaulding Rehabilitation Hospital, Aurora, Colorado 80011, USA
Brain Inj 19:323-30. 2005..To explore the effectiveness of constraint-induced therapy (CIT) in the treatment of individuals with moderate chronic upper extremity paresis...
Geriatric Treatment Center: a contemporary model for collaboration between psychiatry and neurologyChristopher M Filley
Department of Neurology, University of Colorado School of Medicine, Denver, USA
J Neuropsychiatry Clin Neurosci 14:344-50. 2002..This series highlights the value of collaboration between psychiatry and neurology for evaluation and treatment of older patients with neuropsychiatric problems not easily accommodated by many existing health care settings...
Pathological laughing and crying : epidemiology, pathophysiology and treatmentHal S Wortzel
Brain Injury Rehabilitation Unit, HealthONE Spalding Rehabilitation Hospital, Aurora, Colorado, USA
CNS Drugs 22:531-45. 2008....
Cognitive sequelae of hypoxic-ischemic brain injury: a reviewC Alan Anderson
Behavioral Neurology Section, Department of Neurology, University of Colorado School of Medicine, Denver, CO 80045, USA
NeuroRehabilitation 26:47-63. 2010..Cognitive outcomes after HI-BI are discussed and suggestions for the nonpharmacologic and pharmacologic neurorehabilitation of these problems are offered...
Alterations in tonotopy and auditory cerebral asymmetry in schizophreniaDonald C Rojas
Department of Psychiatry, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Biol Psychiatry 52:32-9. 2002..Alterations in fundamental sensory organization may underlie or interact with higher order cognitive mechanisms to produce changes in cognitive task performance...
The neuroendocrine effects of traumatic brain injuryMicol S Rothman
Department of Medicine, University of Colorado, Denver, USA
J Neuropsychiatry Clin Neurosci 19:363-72. 2007..This article reviews the clinical spectrum of neuroendocrine deficits after TBI and their underlying mechanisms. Future studies of the effects of hormonal replacement on recovery are recommended...
Persistent neurobehavioral signs and symptoms following West Nile feverDeborah A Hall
J Neuropsychiatry Clin Neurosci 20:122-3. 2008
Neuropsychiatric complications of traumatic brain injury: a critical review of the literature (a report by the ANPA Committee on Research)Edward Kim
Bristol Myers Squibb Company, Neuroscience Medical Strategy, 777 Scudders Mill Road, Plainsboro, NJ 08536, USA
J Neuropsychiatry Clin Neurosci 19:106-27. 2007..Larger multicenter prospective studies using standardized diagnostic instruments are needed to further clarify the nosology, risk factors, and clinical course of these disorders. Specific directions for research are provided...
Treatment of intractable hiccups with olanzapine following recent severe traumatic brain injuryBenjamin S Alderfer
J Neuropsychiatry Clin Neurosci 18:551-2. 2006
Defining and diagnosing involuntary emotional expression disorderJeffrey L Cummings
Alzheimer's Disease Center, Department of Neurology at David Geffen School of Medicine, University of California, Los Angeles, California, USA
CNS Spectr 11:1-7. 2006..The authors propose a unifying term, involuntary emotional expression disorder (IEED), and provide diagnostic criteria for this disorder...
Diagnosis and management of pathological laughter and cryingJosef Parvizi
Department of Neurology, University of California Los Angeles, 710 Westwood Plaza, Los Angeles, CA 90095, USA
Mayo Clin Proc 81:1482-6. 2006..This article focuses on the clinical presentation, diagnosis, prevalence, and proposed pathophysiological mechanisms of and available treatment options for this clinical phenomenon...
The value of quantitative electroencephalography in clinical psychiatry: a report by the Committee on Research of the American Neuropsychiatric AssociationKerry L Coburn
Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, Macon, Georgia 31201, USA
J Neuropsychiatry Clin Neurosci 18:460-500. 2006..As a clinical laboratory test, qEEG's cautious use is recommended in attentional and learning disabilities of childhood, and in mood and dementing disorders of adulthood...
