Sergio Arce

Summary

Affiliation: University at Buffalo
Country: USA

Publications

  1. pmc In vitro induction of immunoglobulin A (IgA)- and IgM-secreting plasma blasts by cholera toxin depends on T-cell help and is mediated by CD154 up-regulation and inhibition of gamma interferon synthesis
    Sergio Arce
    The Department of Microbiology and Immunology, School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, 138 Farber Hall, 3435 Main St, Buffalo, NY 14214, USA
    Infect Immun 75:1413-23. 2007
  2. pmc Differential binding of Escherichia coli enterotoxins LT-IIa and LT-IIb and of cholera toxin elicits differences in apoptosis, proliferation, and activation of lymphoid cells
    Sergio Arce
    Department of Microbiology and Immunology, The University of Buffalo, State University of New York at Buffalo, 138 Farber Hall, 3435 Main St, Buffalo, NY 12214, USA
    Infect Immun 73:2718-27. 2005
  3. pmc Mutants of type II heat-labile enterotoxin LT-IIa with altered ganglioside-binding activities and diminished toxicity are potent mucosal adjuvants
    Hesham F Nawar
    The Witebsky Center for Microbial Pathogenesis and Immunology, The Department of Microbiology and Immunology, University at Buffalo, Buffalo, New York 14214, USA
    Infect Immun 75:621-33. 2007
  4. pmc Mucosal adjuvant properties of mutant LT-IIa and LT-IIb enterotoxins that exhibit altered ganglioside-binding activities
    Hesham F Nawar
    Department of Microbiology and Immunology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 138 Farber Hall, 3435 Main St, Buffalo, NY 14214, USA
    Infect Immun 73:1330-42. 2005
  5. ncbi Regulation of CXCR3 and CXCR4 expression during terminal differentiation of memory B cells into plasma cells
    Gwendolin Muehlinghaus
    Deutsches Rheumaforschungszentrum, Department for Humoral Immunology, Schumannstrasse 21 22, D 10117 Berlin, Germany
    Blood 105:3965-71. 2005
  6. ncbi CD38 low IgG-secreting cells are precursors of various CD38 high-expressing plasma cell populations
    Sergio Arce
    Deutsches Rheuma ForschungsZentrum Berlin, Schumannstrasse 20 21, D 10117 Berlin, Germany
    J Leukoc Biol 75:1022-8. 2004
  7. ncbi Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals
    Giuliana Cassese
    Department for Humoral Immunology, Deutsches Rheumaforschungszentrum Berlin, Berlin, Germany
    J Immunol 171:1684-90. 2003
  8. ncbi The role of long-lived plasma cells in autoimmunity
    Sergio Arce
    German Rheumatism Research Center, Berlin, Germany
    Immunobiology 206:558-62. 2002
  9. ncbi Chemotactic responsiveness toward ligands for CXCR3 and CXCR4 is regulated on plasma blasts during the time course of a memory immune response
    Anja E Hauser
    Deutsches Rheuma ForschungsZentrum Berlin, Germany
    J Immunol 169:1277-82. 2002
  10. ncbi Humoral immunity and long-lived plasma cells
    Rudolf A Manz
    Department for Humoral Immunology, German Arthritis Research Centre, Berlin, Schumannstrasse 21 22, Berlin, Germany
    Curr Opin Immunol 14:517-21. 2002

Collaborators

Detail Information

Publications10

  1. pmc In vitro induction of immunoglobulin A (IgA)- and IgM-secreting plasma blasts by cholera toxin depends on T-cell help and is mediated by CD154 up-regulation and inhibition of gamma interferon synthesis
    Sergio Arce
    The Department of Microbiology and Immunology, School of Medicine and Biomedical Sciences, University at Buffalo, SUNY, 138 Farber Hall, 3435 Main St, Buffalo, NY 14214, USA
    Infect Immun 75:1413-23. 2007
    ..Neither LT-IIa or LT-IIb had these effects, indicating that type II enterotoxins augment Ab responses by other mechanisms...
  2. pmc Differential binding of Escherichia coli enterotoxins LT-IIa and LT-IIb and of cholera toxin elicits differences in apoptosis, proliferation, and activation of lymphoid cells
    Sergio Arce
    Department of Microbiology and Immunology, The University of Buffalo, State University of New York at Buffalo, 138 Farber Hall, 3435 Main St, Buffalo, NY 12214, USA
    Infect Immun 73:2718-27. 2005
    ..Thus, LT-IIa, LT-IIb, and CT exhibit distinguishable immunomodulatory properties which are likely dependent upon their capacities to recognize different ganglioside receptors on lymphocytes...
  3. pmc Mutants of type II heat-labile enterotoxin LT-IIa with altered ganglioside-binding activities and diminished toxicity are potent mucosal adjuvants
    Hesham F Nawar
    The Witebsky Center for Microbial Pathogenesis and Immunology, The Department of Microbiology and Immunology, University at Buffalo, Buffalo, New York 14214, USA
    Infect Immun 75:621-33. 2007
    ..LT-IIa(T14I) and LT-IIa(T14D) had extremely diminished toxicities in a mouse Y1 adrenal cell bioassay and reduced abilities to induce the accumulation of intracellular cyclic AMP in a macrophage cell line...
  4. pmc Mucosal adjuvant properties of mutant LT-IIa and LT-IIb enterotoxins that exhibit altered ganglioside-binding activities
    Hesham F Nawar
    Department of Microbiology and Immunology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 138 Farber Hall, 3435 Main St, Buffalo, NY 14214, USA
    Infect Immun 73:1330-42. 2005
    ..In contrast, LT-IIb(T13I) retained binding activity for T cells, B cells, and macrophages, indicating that this immunostimulatory mutant enterotoxin interacts with one or more unknown lymphoid cell receptors...
  5. ncbi Regulation of CXCR3 and CXCR4 expression during terminal differentiation of memory B cells into plasma cells
    Gwendolin Muehlinghaus
    Deutsches Rheumaforschungszentrum, Department for Humoral Immunology, Schumannstrasse 21 22, D 10117 Berlin, Germany
    Blood 105:3965-71. 2005
    ..Once induced in memory B cells, CXCR3 expression remains part of the individual cellular memory...
  6. ncbi CD38 low IgG-secreting cells are precursors of various CD38 high-expressing plasma cell populations
    Sergio Arce
    Deutsches Rheuma ForschungsZentrum Berlin, Schumannstrasse 20 21, D 10117 Berlin, Germany
    J Leukoc Biol 75:1022-8. 2004
    ..These data are compatible with a multistep model for plasma cell differentiation and imply that a common CD38 low IgG-secreting precursor gives rise to a diverse plasma cell compartment...
  7. ncbi Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals
    Giuliana Cassese
    Department for Humoral Immunology, Deutsches Rheumaforschungszentrum Berlin, Berlin, Germany
    J Immunol 171:1684-90. 2003
    ....
  8. ncbi The role of long-lived plasma cells in autoimmunity
    Sergio Arce
    German Rheumatism Research Center, Berlin, Germany
    Immunobiology 206:558-62. 2002
    ..Here, we discuss the potential involvement of long-lived plasma cells in the pathogenesis of autoimmune disease and the consequences it has for the development of effective therapeutic strategies...
  9. ncbi Chemotactic responsiveness toward ligands for CXCR3 and CXCR4 is regulated on plasma blasts during the time course of a memory immune response
    Anja E Hauser
    Deutsches Rheuma ForschungsZentrum Berlin, Germany
    J Immunol 169:1277-82. 2002
    ..e., CXCR3 and CXCR4, in the regulation of plasma blast migration into the bone marrow and/or inflamed tissues...
  10. ncbi Humoral immunity and long-lived plasma cells
    Rudolf A Manz
    Department for Humoral Immunology, German Arthritis Research Centre, Berlin, Schumannstrasse 21 22, Berlin, Germany
    Curr Opin Immunol 14:517-21. 2002
    ....