TOMAS ARAGON

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Messenger RNA targeting to endoplasmic reticulum stress signalling sites
    TOMAS ARAGON
    Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, California 94158 2517, USA
    Nature 457:736-40. 2009
  2. pmc BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response
    David Pincus
    Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, California, United States of America
    PLoS Biol 8:e1000415. 2010
  3. ncbi request reprint Clostridial myonecrosis cluster among injection drug users: a molecular epidemiology investigation
    David R Bangsberg
    Epidemiology and Prevention Interventions Center, Box 1372, Room 301, Bldg 100, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA
    Arch Intern Med 162:517-22. 2002
  4. pmc The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis
    Philipp Kimmig
    Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, United States
    elife 1:e00048. 2012

Collaborators

Detail Information

Publications4

  1. pmc Messenger RNA targeting to endoplasmic reticulum stress signalling sites
    TOMAS ARAGON
    Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, California 94158 2517, USA
    Nature 457:736-40. 2009
    ..Translational repression afforded by the intron fulfils this requirement for HAC1 mRNA. Recruitment of mRNA to signalling centres provides a new paradigm for the control of eukaryotic gene expression...
  2. pmc BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response
    David Pincus
    Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, California, United States of America
    PLoS Biol 8:e1000415. 2010
    ..By contrast, BiP provides a buffer for inactive Ire1 molecules that ensures an appropriate response to restore protein folding homeostasis to the ER by modulating the sensitivity and dynamics of Ire1 activity...
  3. ncbi request reprint Clostridial myonecrosis cluster among injection drug users: a molecular epidemiology investigation
    David R Bangsberg
    Epidemiology and Prevention Interventions Center, Box 1372, Room 301, Bldg 100, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA
    Arch Intern Med 162:517-22. 2002
    ..Other C perfringens isolates from patients, heroin, and the environment were determined to be polyclonal. We postulate that rapid recognition and public health notification led to rapid resolution of the outbreak...
  4. pmc The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis
    Philipp Kimmig
    Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, United States
    elife 1:e00048. 2012
    ..Thus, S. pombe uses a universally conserved stress-sensing machinery in novel ways to maintain homeostasis in the ER.DOI:http://dx.doi.org/10.7554/eLife.00048.001...