Research Topics
Species | A J ApterSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Publications
Advances in adult asthma diagnosis and treatment in 2012: potential therapeutics and gene-environment interactionsAndrea J Apter
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
J Allergy Clin Immunol 131:47-54. 2013....
Advances in adult asthma diagnosis and treatment and health outcomes, education, delivery, and quality in 2011: what goes around comes aroundAndrea J Apter
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
J Allergy Clin Immunol 129:69-75. 2012....
Advances in adult asthma 2006: its risk factors, course, and managementAndrea J Apter
Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA, USA
J Allergy Clin Immunol 119:563-6. 2007..This Advances article updates our understanding of risk factors for asthma and its course and management. Studies relevant to clinical practice are discussed, with special attention to their clinical research methods...
Exposure to community violence is associated with asthma hospitalizations and emergency department visitsAndrea J Apter
Section of Allergy and Immunology, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA, USA
J Allergy Clin Immunol 126:552-7. 2010..Exposure to community violence (ECV) has been associated with asthma morbidity of children living in inner-city neighborhoods...
Linking numeracy and asthma-related quality of lifeAndrea J Apter
Division of Pulmonary, Allergy, Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Patient Educ Couns 75:386-91. 2009..To examine the correlation of numerical skills used in patients' self-management of asthma with asthma-related quality of life (AQOL)...
Advances in adult asthma diagnosis and treatment and HEDQ in 2010Andrea J Apter
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
J Allergy Clin Immunol 127:116-22. 2011....
Advances in adult and pediatric asthmaAndrea J Apter
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia 19104, USA
J Allergy Clin Immunol 117:512-8. 2006..Meanwhile, more effective health care strategies must be developed to reduce the reported disparities in asthma care noted in our patient populations...
Is there cross-reactivity between penicillins and cephalosporins?Andrea J Apter
Division of Pulmonary, Allergy Critical Care Medicine, Department of Medicine, Philadelphia, PA, USA
Am J Med 119:354.e11-9. 2006..We sought to determine the risk of an allergic reaction to a cephalosporin exposure in those with prior penicillin reactions...
Problem solving to improve adherence and asthma outcomes in urban adults with moderate or severe asthma: a randomized controlled trialAndrea J Apter
Allergy and Immunology Section, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA, USA
J Allergy Clin Immunol 128:516-23.e1-5. 2011..Improving inhaled corticosteroid (ICS) adherence should improve asthma outcomes...
Numeracy and communication with patients: they are counting on usAndrea J Apter
Department of Medicine, Division of Pulmonary, University of Pennsylvania, Philadelphia, PA, USA
J Gen Intern Med 23:2117-24. 2008..This information is integrated into a hierarchical model of mathematical concepts and skills, which can guide clinicians toward numerical communication that is easier to use with patients...
Clinical and genetic risk factors of self-reported penicillin allergyAndrea J Apter
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, USA
J Allergy Clin Immunol 122:152-8. 2008..Patients with self-reported penicillin allergy are frequently denied beta-lactam antibiotics...
Asthma numeracy skill and health literacyAndrea J Apter
Division of Pulmonary, Allergy Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
J Asthma 43:705-10. 2006..At higher STOFHLA levels there was a wide range of the total number of correct numeracy responses. Numeracy is a unique and important component of health literacy...
Advances in adult asthma diagnosis and treatment and health outcomes, education, delivery, and quality in 2008Andrea J Apter
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
J Allergy Clin Immunol 123:35-40. 2009..In contrast with these advances, however, disparity in asthma morbidity persists: black persons compared with white persons have a 4-fold greater risk of an asthma-related emergency department visit...
Advances in the care of adults with asthma and allergy in 2007Andrea J Apter
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
J Allergy Clin Immunol 121:839-44. 2008..This review focuses on the Journal articles published in 2007 pertaining to risk and impairment in adult asthma and interventions to improve its control...
Testing the reliability of old and new features of a new electronic monitor for metered dose inhalersA J Apter
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
Ann Allergy Asthma Immunol 86:421-4. 2001..Electronic monitors are the most accurate means available for measuring adherence, but their use has been limited by reports questioning the reliability and validity of their data...
Assessing the quality of asthma care provided to Medicaid patients enrolled in managed care organizations in ConnecticutA J Apter
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
Ann Allergy Asthma Immunol 86:211-8. 2001..Many states have enrolled Medicaid beneficiaries in managed care organizations (MCOs). Few assessments of the quality of asthma care provided by these new programs are available...
Advances in adult asthma diagnosis and treatment in 2009Andrea J Apter
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
J Allergy Clin Immunol 125:79-84. 2010..In this review of asthma-related publications from the Journal in 2009, efforts to standardize methodology and reporting of translational research, the influence of the environment, therapeutics, and management of asthma are highlighted...
Adherence with twice-daily dosing of inhaled steroids. Socioeconomic and health-belief differencesA J Apter
Department of Medicine, University of Connecticut Health Center, Farmington, CT 06030 3945, USA
Am J Respir Crit Care Med 157:1810-7. 1998..2; CI: 1.01 to 1.55) were independently associated with poor adherence. These results emphasize the importance of socioeconomic status and adequate patient-clinician communication for adherence to inhaled-steroid schedules...
Adolescents and asthma: why bother with our meds?David R Naimi
Division of Allergy and Immunology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
J Allergy Clin Immunol 123:1335-41. 2009..Adherence to inhaled steroid regimens for asthma is poor in adults and children. Although it is assumed that nonadherence contributes to morbidity in older adolescents, investigation is limited...
Communities and health: the case of inner-city violence and asthmaAndrea J Apter
Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA 19104, USA
LDI Issue Brief 16:1-4. 2010....
Adherence logger for a dry powder inhaler: a new device for medical adherence researchDaniel Bogen
Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA
J Allergy Clin Immunol 114:863-8. 2004..Finding ways to improve adherence depends on the ability to measure time and date of inhaler use reliably and to detect deliberate dose dumping. There is no such monitor for the popular new dry powder inhalers...
Gaining insight into patients' beliefs using qualitative research methodologiesMaureen George
Division of Pulmonary, Allergy Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Curr Opin Allergy Clin Immunol 4:185-9. 2004..This review serves as a primer for those health care professionals who are unfamiliar with this alternative research paradigm...
A 65-year-old woman with intractable nasal congestionShilpi Narula
Division of Pulmonary, Allergy, and Critical Care Medicine, Hospital of University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Ann Allergy Asthma Immunol 96:281-5. 2006
Modifiable barriers to adherence to inhaled steroids among adults with asthma: it's not just black and whiteAndrea J Apter
Division of Pulmonary, Allergy Critical Care Medicine, Department of Medicine, University of Pennsylvania, 3600 Spruce Street, Philadelphia, PA 19104, USA
J Allergy Clin Immunol 111:1219-26. 2003..CONCLUSION: Attitude is strongly related to adherence but does not mediate the effect of race-ethnicity...
Reacting to antibiotic allergiesAndrea J Apter
Center for Clinical Epidemiology and Biostatistics, Center for Education and Research on Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, USA
LDI Issue Brief 11:1-4. 2006....
Qualitative research-enhanced understanding of patients' beliefs: results of focus groups with low-income, urban, African American adults with asthmaMaureen George
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, PA 19104, USA
J Allergy Clin Immunol 111:967-73. 2003..Qualitative research is an important tool for formulating hypotheses for improving ICS adherence that can then be tested in the future by using quantitative research methods...
Absence of cross-reactivity between sulfonamide antibiotics and sulfonamide nonantibioticsBrian L Strom
Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
N Engl J Med 349:1628-35. 2003..The safety of sulfonamide nonantibiotics is unclear in patients with prior allergic reactions to sulfonamide antibiotics...
Advances in adult and pediatric asthmaAndrea J Apter
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, USA
J Allergy Clin Immunol 113:407-14. 2004..Our community has a strong commitment to health care quality, education, and delivery. The Journal will reflect this commitment with a new section devoted to these issues...
Clearing clinical barriers: enhancing social support using a patient navigator for asthma careHeather L Black
Section of Allergy and Immunology, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Asthma 47:913-9. 2010..Patients with moderate or severe asthma, particularly those who are minority or poor, often encounter significant personal, clinical practice, and health system barriers to accessing care...
Clinical advances in adult asthmaAndrea J Apter
Division of Pulmonary, Allergy, Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
J Allergy Clin Immunol 111:S780-4. 2003..The use of chlorofluorocarbon-free medications for asthma is increasing. Medications comprise the largest cost category for asthma...
Represcription of penicillin after allergic-like eventsAndrea J Apter
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, 3600 Spruce Street, Philadelphia, PA 19104, USA
J Allergy Clin Immunol 113:764-70. 2004..72%). Represcription of penicillin to such patients is more frequent than anticipated...
Influences of earlier adherence and symptoms on current symptoms: a marginal structural models analysisClara Kim
Center for Clinical Epidemiology and Biostatistics, Department of Medicine, University of Pennsylvania, 3600 Spruce Street, Philadelphia, PA 19104, USA
J Allergy Clin Immunol 115:810-4. 2005..These analyses are important for understanding time-varying measures in the clinical setting...
Early exposure to allergen: is this the cat's meow, or are we barking up the wrong tree?Andrea J Apter
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia 19104, USA
J Allergy Clin Immunol 111:938-46. 2003..This article discusses some of the epidemiologic issues in interpreting these studies. Review of relevant epidemiology demonstrates that much research remains to be performed before these interesting hypotheses are proved or disproved...
Steroid phobia and adherence--problems, solutions, impact on benefit/risk profileVivek U Rao
Division of Pulmonary, Allergy, Critical Care, Department of Medicine, 829 Gates Building, Hospital of the University of Pennsylvania, 3600 Spruce Street, Philadelphia, PA 19104, USA
Immunol Allergy Clin North Am 25:581-95. 2005..If the provider is able to effectively communicate and convince the patient of the benefit/risk ratio of steroids, improved patient outcomes can be achieved...
Validation of a beta-agonist long-term asthma control scale derived from computerized pharmacy dataMichael Schatz
Department of Allergy San Diego, Kaiser Permanente Medical Care Program, Kaiser Permanente Medical Center, CA 92111, USA
J Allergy Clin Immunol 117:995-1000. 2006..Asthma control has been defined clinically by using validated tools, but an asthma control scale using administrative data has not been reported...
Patients with asthma who do not fill their inhaled corticosteroids: a study of primary nonadherenceL Keoki Williams
Department of Internal Medicine, Henry Ford Hospital, Detroit, MI, USA
J Allergy Clin Immunol 120:1153-9. 2007..Adherence to inhaled corticosteroids (ICSs) is known to be poor among patients with asthma; however, little is known about patients who do not fill their ICS prescriptions (ie, primary nonadherence)...
Unconventional risk factors: another pathway to understanding health disparitiesPeter J Gergen
J Allergy Clin Immunol 119:165-7. 2007
Development and validation of a medication intensity scale derived from computerized pharmacy data that predicts emergency hospital utilization for persistent asthmaMichael Schatz
Kaiser Permanente Medical Center, 7060 Clairemont Mesa Blvd, San Diego, CA 92111, USA
Am J Manag Care 12:478-84. 2006..To validate a risk stratification scheme using computerized pharmacy data to predict emergency hospital utilization for persistent asthma...
The influence of health disparities on individual patient outcomes: what is the link between genes and environment?Andrea J Apter
J Allergy Clin Immunol 117:345-50. 2006
Relationships among quality of life, severity, and control measures in asthma: an evaluation using factor analysisMichael Schatz
Department of Allergy, Kaiser Permanente Medical Center, San Diego, CA 92111, USA
J Allergy Clin Immunol 115:1049-55. 2005..Validated psychometric tools measuring quality of life, asthma control, and asthma severity have been developed, but their relationships with each other and with other important patient-centered outcomes have not been rigorously assessed...
The controller-to-total asthma medication ratio is associated with patient-centered as well as utilization outcomesMichael Schatz
Department of Allergy, Kaiser Permanente Medical Center Program, 7060 Clairemont Mesa Blvd, San Diego, CA 92111, USA
Chest 130:43-50. 2006..The ratio of controller medication to total asthma medications has been related to asthma utilization outcomes, but its relationship to patient-centered outcomes has not been explored...
Mind the widening gap: have improvements in asthma care increased asthma disparities?Cynthia S Rand
J Allergy Clin Immunol 122:319-21. 2008
Relationship of validated psychometric tools to subsequent medical utilization for asthmaMichael Schatz
Department of Allergy, Kaiser Permanente Medical Center, San Diego, Calif 92111, USA
J Allergy Clin Immunol 115:564-70. 2005..Risk stratification is used to identify patients with asthma at increased risk of experiencing morbidity and resource utilization. Validated psychometric tools are infrequently studied sources of data for this purpose...
Improved asthma outcomes from allergy specialist care: a population-based cross-sectional analysisMichael Schatz
Department of Allergy, San Diego, CA 92111, USA
J Allergy Clin Immunol 116:1307-13. 2005..Prior studies suggest that allergist care improves asthma outcomes, but many of these studies have methodological shortcomings...
Stratifying medical and pharmaceutical administrative claims as a method to identify pediatric asthma patients in a Medicaid managed care organizationJoan E Twiggs
Department of Sociology, Anthropology and Social Work, Kansas State University, 204 Waters Hall, Manhattan, KS 66506, USA
J Clin Epidemiol 55:938-44. 2002..The Medicaid Managed Care Organization can begin to identify its asthma population using the stratification meth...
Research Grants
- INHALED STEROID ADHERENCE IN MODERATE & SEVERE ASTHMAAndrea Apter; Fiscal Year: 2004..Upon the foundation of my prior clinical experience and education, this training program is designed to equip me with the additional skills and research experience necessary to become a fully independent investigator. ..
- Individualized Interventions to Improve Asthma AdherenceAndrea Apter; Fiscal Year: 2007..We will estimate the incremental cost-effectiveness of PS. ..
- Literacy and improving patient-clinician encounters for AsthmaAndrea Apter; Fiscal Year: 2007..others, and participating in relevant research working groups, I will create a team of expert collaborators in health and literacy, education, bioenqineerinq (directed at behavior measurement), and behavioral medicine (End of Abstract) ..
- Individualized Interventions to Improve Asthma AdherenceAndrea Apter; Fiscal Year: 2009..We will estimate the incremental cost-effectiveness of PS. ..
- Individualized Interventions to Improve Asthma AdherenceAndrea Apter; Fiscal Year: 2009..We will estimate the incremental cost-effectiveness of PS. ..
