S K Apple

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Comparison of fluorescent in situ hybridization HER-2/neu results on core needle biopsy and excisional biopsy in primary breast cancer
    Sophia K Apple
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, UCLA Center for the Health Sciences, Los Angeles, CA 90095, USA
    Mod Pathol 22:1151-9. 2009
  2. ncbi request reprint Sebaceous adenoma of the parotid gland: a case report with fine needle aspiration findings and histologic correlation
    Sophia K Apple
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles Center for the Health Sciences, Los Angeles, California 90095 1732, USA
    Acta Cytol 53:419-22. 2009
  3. doi request reprint Accurate classification of sentinel lymph node metastases in patients with lobular breast carcinoma
    Sophia K Apple
    UCLA Path and Lab Med, University of California Los Angeles, CA 90095 1732, USA
    Breast 19:360-4. 2010
  4. pmc Significance of lobular intraepithelial neoplasia at margins of breast conservation specimens: a report of 38 cases and literature review
    Sophia K Apple
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, U, S, A, Box 951732, 1P 244 CHS Los Angeles, CA 90095 1732 USA
    Diagn Pathol 5:54. 2010
  5. ncbi request reprint Variability in gross and microscopic pathology reporting in excisional biopsies of breast cancer tissue
    Sophia K Apple
    Department of Pathology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095 1732, USA
    Breast J 12:145-9. 2006
  6. ncbi request reprint How do we measure a residual tumor size in histopathology (the gold standard) after neoadjuvant chemotherapy?
    S K Apple
    Department of Pathology Center of Health Science CHS, David Geffen School of Medicine at University of California at Los Angeles, Mail Code 173216, 10833 Le Conte Avenue Los Angeles, CA 90095 1732, USA
    Breast 15:370-6. 2006
  7. ncbi request reprint Invasive ductal carcinoma with tissue neutrophilia: a distinct entity?
    Sophia K Apple
    Department of Pathology, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, CA, USA
    Breast 13:519-21. 2004
  8. ncbi request reprint Histopathologic characteristics predicting HER-2/neu amplification in breast cancer
    Raquel Prati
    Department of Surgery, Revlon UCLA Breast Center, UCLA Medical Center, Gonda UCLA Breast Cancer Research Laboratory, Los Angeles, California 90095 7028, USA
    Breast J 11:433-9. 2005
  9. doi request reprint A correlation study of diagnostic fine-needle aspiration with histologic diagnosis in cystic neck lesions
    Neda A Moatamed
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Diagn Cytopathol 37:720-6. 2009
  10. doi request reprint Should histologic type be taken into account when considering neoadjuvant chemotherapy in breast carcinoma?
    Peggy S Sullivan
    Department of Pathology and Laboratory Medicine, David E Geffen School of Medicine, Los Angeles, California 90095, USA
    Breast J 15:146-54. 2009

Collaborators

Detail Information

Publications23

  1. doi request reprint Comparison of fluorescent in situ hybridization HER-2/neu results on core needle biopsy and excisional biopsy in primary breast cancer
    Sophia K Apple
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, UCLA Center for the Health Sciences, Los Angeles, CA 90095, USA
    Mod Pathol 22:1151-9. 2009
    ....
  2. ncbi request reprint Sebaceous adenoma of the parotid gland: a case report with fine needle aspiration findings and histologic correlation
    Sophia K Apple
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles Center for the Health Sciences, Los Angeles, California 90095 1732, USA
    Acta Cytol 53:419-22. 2009
    ..In particular, recognition of this entity in cytologic specimens is important to avoid radical surgery...
  3. doi request reprint Accurate classification of sentinel lymph node metastases in patients with lobular breast carcinoma
    Sophia K Apple
    UCLA Path and Lab Med, University of California Los Angeles, CA 90095 1732, USA
    Breast 19:360-4. 2010
    ..The criteria for assessing small volume metastases in the sentinel lymph node of patients with invasive lobular carcinoma need to be more clearly defined...
  4. pmc Significance of lobular intraepithelial neoplasia at margins of breast conservation specimens: a report of 38 cases and literature review
    Sophia K Apple
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, U, S, A, Box 951732, 1P 244 CHS Los Angeles, CA 90095 1732 USA
    Diagn Pathol 5:54. 2010
    ..The aim is to determine whether there is an increase incidence of recurrence when LIN is found at surgical margins on BCT...
  5. ncbi request reprint Variability in gross and microscopic pathology reporting in excisional biopsies of breast cancer tissue
    Sophia K Apple
    Department of Pathology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095 1732, USA
    Breast J 12:145-9. 2006
    ..The surgical margin status was reported in only 76% of the final diagnoses. This study shows that the pathology reports were heterogeneous with respect to reporting gross and microscopic final diagnoses from the variable hospitals...
  6. ncbi request reprint How do we measure a residual tumor size in histopathology (the gold standard) after neoadjuvant chemotherapy?
    S K Apple
    Department of Pathology Center of Health Science CHS, David Geffen School of Medicine at University of California at Los Angeles, Mail Code 173216, 10833 Le Conte Avenue Los Angeles, CA 90095 1732, USA
    Breast 15:370-6. 2006
    ..Determining accurate residual tumor size to estimate pathologic response to chemotherapy is essential. We attempted to provide guidelines for pathology reporting post-neoadjuvant chemotherapy on breast cancers...
  7. ncbi request reprint Invasive ductal carcinoma with tissue neutrophilia: a distinct entity?
    Sophia K Apple
    Department of Pathology, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, CA, USA
    Breast 13:519-21. 2004
    ..A case report is described with cytomorphologic features of FNA and histopathology with immunohistochemical features...
  8. ncbi request reprint Histopathologic characteristics predicting HER-2/neu amplification in breast cancer
    Raquel Prati
    Department of Surgery, Revlon UCLA Breast Center, UCLA Medical Center, Gonda UCLA Breast Cancer Research Laboratory, Los Angeles, California 90095 7028, USA
    Breast J 11:433-9. 2005
    ..15%, p=0.0016). FISH-determined HER-2/neu status is not associated with histologic type, tumor size, nodal status, lymph-vascular invasion, or patient age...
  9. doi request reprint A correlation study of diagnostic fine-needle aspiration with histologic diagnosis in cystic neck lesions
    Neda A Moatamed
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Diagn Cytopathol 37:720-6. 2009
    ..The overall performance of the FNA showed 76% sensitivity and 100% specificity. In conclusion, FNA of the cystic neck lesions offers an invaluable and highly specific initial diagnostic approach for the management of the patients...
  10. doi request reprint Should histologic type be taken into account when considering neoadjuvant chemotherapy in breast carcinoma?
    Peggy S Sullivan
    Department of Pathology and Laboratory Medicine, David E Geffen School of Medicine, Los Angeles, California 90095, USA
    Breast J 15:146-54. 2009
    ..Lobular carcinomas respond poorly to neoadjuvant chemotherapy as evidence by lack of complete pathologic response and rare histologic tissue response...
  11. pmc Does size matter? Comparison study between MRI, gross, and microscopic tumor sizes in breast cancer in lumpectomy specimens
    Bita Behjatnia
    Department of Pathology, 3405 E Hammond Cir Unit F, Orange, CA, USA
    Int J Clin Exp Pathol 3:303-9. 2010
    ..Microscopic measurements of tumor size are necessary for accurate T-staging and recommended for appropriate patient management...
  12. ncbi request reprint Do the histologic features and results of breast cancer biomarker studies differ between core biopsy and surgical excision specimens?
    Chandra N Burge
    Department of Pathology, David Geffen School of Medicine at University of California at Los Angeles, Mail Code 173216, 10833 Le Conte Avenue, Los Angeles, CA 90095 1732, USA
    Breast 15:167-72. 2006
    ..Although breast cancer may have heterogeneous histological and immunohistochemical findings, our study shows that relatively high concordance rates can be obtained when comparing core and excisional biopsy specimens...
  13. doi request reprint HER2 in well differentiated breast cancer: is testing necessary?
    G Kenneth Haines
    Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA
    Breast Cancer Res Treat 112:551-6. 2008
    ....
  14. doi request reprint Fine needle aspiration of pigmented villonodular synovitis of the temporomandibular joint
    David Y Lu
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Diagn Cytopathol 39:45-8. 2011
    ..The differential diagnosis of PVNS in the context of its location in and around the TMJ is also discussed...
  15. ncbi request reprint Extensive sampling changes T-staging of infiltrating lobular carcinoma of breast: a comparative study of gross versus microscopic tumor sizes
    Neda A Moatamed
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California at Los Angeles, Los Angeles, California 90095, USA
    Breast J 12:511-7. 2006
    ..Therefore, the T-stages of the tumors with a gross size of 5 cm or less may change by microscopic resizing after an extensive sampling of the specimen...
  16. doi request reprint Reflex high risk HPV testing in atypical squamous cells, cannot exclude high grade intraepithelial lesion: a large institution's experience with the significance of this often ordered test
    Gretchen E Galliano
    Department of Pathology, Division of Cytopathology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1732, USA
    Acta Cytol 55:167-72. 2011
    ..Cervical cytology specimens diagnosed with ASC-H consist of squamous cells with equivocal cytology for high-grade dysplastic lesions. We reviewed our cases of ASC-H with reflex HPV testing to evaluate this patient population...
  17. ncbi request reprint Comparative polymerase chain reaction analysis of c-myc amplification on archival breast fine-needle aspiration materials
    J Y Rao
    Department of Pathology and Laboratory Medicine, University of California at Los Angeles Medical Center, 90095 1732, USA
    Cancer Epidemiol Biomarkers Prev 9:175-9. 2000
    ..The results of this study suggest that c-myc amplification may be a biomarker of breast cancer risk. However, additional large, prospective studies are needed to confirm the current observation...
  18. doi request reprint A retrospective study of the diagnostic accuracy of fine-needle aspiration for breast lesions and implications for future use
    Christina Day
    Department of Pathology and Lab Medicine, David Geffen Medical School, Center of Health Science, University of California at Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095 1732, USA
    Diagn Cytopathol 36:855-60. 2008
    ..Although FNA may not be ideal in the initial evaluation of suspicious lesions, we argue that FNA for clinically benign palpable lesions and recurrent carcinomas has significant value...
  19. doi request reprint Heterotopic breast tissue versus occult metastatic carcinoma in lymph node, a diagnostic dilemma
    Steven J Ohsie
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Ann Diagn Pathol 14:260-3. 2010
    ..The diagnosis of occult metastatic tumor was based on the lack of the myoepithelial layers associated with the ductal structures. The diagnostic dilemma of the differential diagnoses is discussed, and pertinent literature is reviewed...
  20. ncbi request reprint Interventional breast imaging: current procedures and assessing for concordance with pathology
    Lawrence W Bassett
    Department of Radiology, David Geffen School of Medicine at the University of California, Los Angeles, 200 UCLA Medical Plaza, Room 165 47, Box 956952, Los Angeles, CA 90095, USA
    Radiol Clin North Am 45:881-94, vii. 2007
    ..The second portion of the article addresses the management of the patient after the biopsy, including assessment for concordance of radiology and pathology findings and potential underestimation of disease...
  21. doi request reprint Is a short-interval postradiation mammogram necessary after conservative surgery and radiation in breast cancer?
    Kevin Lin
    Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA 90095, USA
    Int J Radiat Oncol Biol Phys 72:1041-7. 2008
    ..To examine, in a retrospective study, whether the initial posttreatment mammogram offers any benefit to patients...
  22. ncbi request reprint Mucinous adenocarcinomas of the thymus: report of 2 cases and review of the literature
    Seong H Ra
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Los Angeles, CA 90095 1732, USA
    Am J Surg Pathol 31:1330-6. 2007
    ..Most adenocarcinomas of the mediastinum are metastatic lesions. Primary thymic adenocarcinomas are extremely rare neoplasms. We could find only 12 cases reported in the literature; of these 12, only 4 were of the mucinous subtype...
  23. doi request reprint A correlation study on diagnostic endoscopic ultrasound-guided fine-needle aspiration of lymph nodes with histological and clinical diagnoses, the UCLA Medical Center experience
    Bita V Naini
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Diagn Cytopathol 36:460-6. 2008
    ..In conclusion, EUS-FNA offers an invaluable approach for diagnostic examination of the internal lymph nodes where percutaneous FNA is either difficult or impossible. impossible...