Research Topics
| Henry D AppelmanSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
Angiosarcoma, radiation-associated angiosarcoma, and atypical vascular lesionDavid R Lucas
Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA
Arch Pathol Lab Med 133:1804-9. 2009..Recently, vascular-type atypical vascular lesion, which resembles hemangioma, has been described, thus expanding the definition of this entity...- Adenocarcinoma in Barrett mucosa treated by endoscopic mucosal resectionHenry D Appelman
Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA
Arch Pathol Lab Med 133:1793-7. 2009..Hopefully, better diagnostic criteria will arise, and perhaps a new histologic stain or a molecular or genetic test will emerge that complements "our eyeballs.".. - A histologically defined subset of high-grade dysplasia in Barrett mucosa is predictive of associated carcinomaWeijian Zhu
Department of Pathology, University of Michigan, Ann Arbor, MI 48109 0054, USA
Am J Clin Pathol 132:94-100. 2009..Our findings highlight the evolution of diagnostic criteria for Barrett dysplasia... - Sloughing esophagitis is associated with chronic debilitation and medications that injure the esophageal mucosaJulianne K Purdy
Department of Pathology, University of Michigan Medical Center, Ann Arbor, MI, USA
Mod Pathol 25:767-75. 2012.... - Barrett's esophagus: natural historyHenry D Appelman
Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA
Ann N Y Acad Sci 1232:292-308. 2011.... 
Dysplasia can be a pain in the gutBarbara J McKenna
Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA
Pathology 34:518-28. 2002..This paper follows the evolution of the dysplasia concept, details the difficult areas of diagnosis, and discusses the importance of interaction between clinicians and pathologists in dealing with dysplasias...- Primer: histopathology for the clinician--how to interpret biopsy information for gastritisBarbara J McKenna
Department of Pathology, University of Michigan, Ann Arbor, MI, USA
Nat Clin Pract Gastroenterol Hepatol 3:165-71. 2006..Second, there are a limited number of well-known histologic gastritides that yield specific diagnoses. Reports that are purely descriptive are, therefore, common, and might require discussion between endoscopist and pathologist... - OsteoblastomaDavid R Lucas
Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA
Arch Pathol Lab Med 134:1460-6. 2010.... - Sino-orbital osteoma: a clinicopathologic study of 45 surgically treated cases with emphasis on tumors with osteoblastoma-like featuresJonathan B McHugh
Department of Pathology, University of Michigan Health System, Ann Arbor, MI 48109 0054, USA
Arch Pathol Lab Med 133:1587-93. 2009..Osteomas may have osteoblastoma-like areas and distinguishing it from true osteoblastoma can be challenging. Some believe osteomas with osteoblastoma-like features behave more aggressively... - Histologic alterations from neoadjuvant chemotherapy in high-grade extremity soft tissue sarcoma: clinicopathological correlationDavid R Lucas
Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109 0054, USA
Oncologist 13:451-8. 2008.... - Identification of SYT-SSX transcripts from synovial sarcomas using RT-multiplex PCR and capillary electrophoresisJohn A Thorson
Department of Pathology, University of Michigan, Ann Arbor, MI 48105, USA
Mod Pathol 19:641-7. 2006..One-step RT-multiplex PCR combined with capillary electrophoresis is a rapid and accurate method for the detection and genotypic classification of SYT-SSX transcripts from fixed tissue specimens... - Adjuvant therapy of osteosarcoma--A Phase II trial: Southwest Oncology Group study 9139Mark M Zalupski
Department of Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA
Cancer 100:818-25. 2004.... - Dedifferentiated liposarcoma with inflammatory myofibroblastic tumor-like featuresDavid R Lucas
Department of Pathology, University of Michigan, Ann Arbor, MI 48109 0054, USA
Am J Surg Pathol 34:844-51. 2010..Awareness of this finding can prevent one from misdiagnosing dedifferentiated liposarcoma as inflammatory myofibroblastic tumor, a much less aggressive neoplasm... - Lymphocytic esophagitis: a chronic or recurring pattern of esophagitis resembling allergic contact dermatitisJulianne K Purdy
Department of Pathology, University of Michigan, Ann Arbor, MI 48109 0054, USA
Am J Clin Pathol 130:508-13. 2008..Patients with LE are statistically no more likely than control subjects to have CD. We found no association between LE and any clinical condition or symptom. Based on sequential biopsies in 7 patients, LE seems to be a chronic disease... - Morphologic findings in upper gastrointestinal biopsies of patients with ulcerative colitis: a controlled studyJingmei Lin
Department of Pathology, University of Michigan, Ann Arbor, MI 48109 0054, USA
Am J Surg Pathol 34:1672-7. 2010..However, the frequency and types of inflammation in upper gastrointestinal biopsies in patients with UC has not been well studied, especially in a controlled study... - Fine-needle aspiration of spinal osteoblastoma in a patient with lymphangiomatosisMichael G Rhode
Department of Pathology, University of Michigan Medical School, Ann Arbor, USA
Diagn Cytopathol 34:295-7. 2006..We believe that this is the first case reporting an osteoblastoma diagnosed by FNA in a lymphangiomatosis patient. We describe the clinical and cytological findings of osteoblastoma and its differential diagnosis... - Cluster analysis of immunohistochemical profiles in synovial sarcoma, malignant peripheral nerve sheath tumor, and Ewing sarcomaStephen H Olsen
Department of Pathology, The University of Michigan Medical School, Ann Arbor, MI 48109-0054, USA
Mod Pathol 19:659-68. 2006..Cluster analysis also highlighted aberrant staining reactions and diagnostic pitfalls in these tumors. Hierarchical cluster analysis is an effective method for analyzing high-volume immunohistochemical data... - Disseminated malignant solitary fibrous tumor of the pleuraHongquan Zhang
Department of Pathology, Harper University Hospital, Wayne State University and Karmanos Cancer Institute, Detroit, MI 48201, USA
Pathol Int 54:111-5. 2004.... - Cardiac pseudosarcomatous fibromyxoid tumor: a review of the literatureAamer Chughtai
Division of Thoracic Radiology, Department of Radiology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
J Comput Assist Tomogr 29:749-51. 2005..No recurrence or metastatic disease has been reported after resection of PFTs elsewhere in the body, and this tumor seems to have a benign clinical course... - Primary versus radiation-associated craniofacial osteosarcoma: Biologic and clinicopathologic comparisonsJonathan B McHugh
Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109-0054, USA
Cancer 107:554-62. 2006..In addition, they demonstrate higher expression rates of adverse prognostic indicators, further highlighting the distinction... - Metastatic shoulder liposarcoma to the right ventricle: CT findingsAamer Chughtai
Department of Radiology, Division of Cardiothoracic Radiology, University of Michigan Medical Center, Ann Arbor, Michigan, USA
J Thorac Imaging 22:195-8. 2007.... 
Adenoma-infiltrating lymphocytes (AILs) are a potential marker of hereditary nonpolyposis colorectal cancerAlexandros D Polydorides
Department of Pathology, University of Michigan Health System, Ann Arbor, MI 48109 0054, USA
Am J Surg Pathol 32:1661-6. 2008..Therefore, increased numbers of AILs and decreased numbers of apoptoses in colorectal adenomas are simple and inexpensive markers that raise the possibility of HNPCC...- Morphology of gastrointestinal stromal tumors: historical perspectivesHenry D Appelman
Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109 5602, USA
J Surg Oncol 104:874-81. 2011..They differ by site in terms of cell type and growth pattern. Benign and malignant tumors are separated based on their light microscopic appearances, size as measured by innumerable pathologists and assistants and mitotic counts... - Benign gastrointestinal mesenchymal BUMPS: a brief review of some spindle cell polyps with published namesAhren C Rittershaus
Department of Pathology, University of Michigan Hospital, Ann Arbor, MI 48109, USA
Arch Pathol Lab Med 135:1311-9. 2011..These include perineuriomas, Schwann cell nodules, ganglioneuromas, leiomyomas of the muscularis mucosae, inflammatory fibroid polyps, and granular cell tumors... - What is dysplasia in the gastrointestinal tract?Henry D Appelman
Department of Pathology, University Hospitals, Ann Arbor, 48109 0054, USA
Arch Pathol Lab Med 129:170-3. 2005..Pathologists need a dysplasia stain or a whole set of new markers of high cancer risk, presumably molecular and/or genetic, that are not dependent on pathologists' diagnoses of dysplasia and their inherent subjectivity... - Seventh O.E.S.O. Congress: gastroesophageal reflux and barrett esophagusGregorio Chejfec
Department of Pathology, University of Illinois, Chicago 60612-7335, USA
Arch Pathol Lab Med 129:157-8. 2005 - Dysplasia in Barrett esophagusChristopher D Lao
Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
Cancer 100:1622-7. 2004..CONCLUSIONS: The confirmed low prevalence of cases of LGD will affect the design of future clinical trials of chemopreventive interventions for Barrett esophagus... - The diagnostic value of endoscopic terminal ileum biopsiesJonathan B McHugh
Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA
Am J Gastroenterol 102:1084-9. 2007..We see many such biopsies in our gastrointestinal pathology service and have been impressed by the subjectively low yield of TI biopsies. Therefore, we studied this to obtain objective data... - Long-term outcomes after radiotherapy for retroperitoneal and deep truncal sarcomaMary Feng
Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI, USA
Int J Radiat Oncol Biol Phys 69:103-10. 2007..To determine the long-term outcomes after multimodality treatment of retroperitoneal, pelvic, and deep truncal sarcomas and to identify the factors associated with local control (LC), distant metastasis (DM), and overall survival (OS)... - Chordoma: the nonsarcoma primary bone tumorRashmi Chugh
Department of Internal Medicine, Division of Hematology Oncology, 24 Frank Lloyd Wright Drive, A3400, P O Box 483, Ann Arbor, Michigan 48106, USA
Oncologist 12:1344-50. 2007..Radiation therapy may also salvage some patients with local recurrence. One series reported a 2-year actuarial local control rate of 33% for patients treated with proton beam irradiation... - Wagner-Meissner neurilemmoma of the right cheekAngela J Wu
Department of Pathology, University of Michigan, MI 48109 0054, USA
Ann Diagn Pathol 12:204-7. 2008.... - Con: High-grade dysplasia and villous features should not be part of the routine diagnosis of colorectal adenomasHenry D Appelman
Department of Pathology, University of Michigan, Ann Arbor, MI 48109-0054, USA
Am J Gastroenterol 103:1329-31. 2008 - Can lymphangiosarcoma be resurrected? A clinicopathological and immunohistochemical study of lymphatic differentiation in 49 angiosarcomasCohra C Mankey
Department of Pathology, University of Michigan, Ann Arbor, MI 48109 0054, USA
Histopathology 56:364-71. 2010..The aim was to investigate further lymphatic antigen expression, and to explore the relation of immunohistochemistry to morphological and clinical findings... - Cluster analysis of immunohistochemical markers in leiomyosarcoma delineates specific anatomic and gender subgroupsJason C Carvalho
Department of Pathology, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0054, USA
Cancer 115:4186-95. 2009..The differential expression of smooth muscle markers, estrogen receptor (ER), progesterone receptor (PR), and Wilms tumor-1 protein (WT1) by anatomic subtype and gender was explored...