Affiliation: University of Pittsburgh
Kullmann F, Clayton D, Ruiz W, Wolf Johnston A, Gauthier C, Kanai A, et al
. Urothelial proliferation and regeneration after spinal cord injury. Am J Physiol Renal Physiol. 2017;313:F85-F102 pubmed publisher
..Thus, unlike the rapid and complete restoration of the urothelium that occurs in response to acute injuries, regions of incompletely differentiated urothelium were observed even 28 days post SCI. ..
Apodaca G. Modulation of membrane traffic by mechanical stimuli. Am J Physiol Renal Physiol. 2002;282:F179-90 pubmed
..Transduction of mechanical stimuli into changes in exocytosis/endocytosis may involve the cytoskeleton, stretch-activated channels, integrins, phospholipases, tyrosine kinases, and cAMP...
Gallo L, Liao Y, Ruiz W, Clayton D, Li M, Liu Y, et al
. TBC1D9B functions as a GTPase-activating protein for Rab11a in polarized MDCK cells. Mol Biol Cell. 2014;25:3779-97 pubmed publisher
..We conclude that TBC1D9B is a Rab11a GAP that regulates basolateral-to-apical transcytosis in polarized MDCK cells. ..
Prakasam H, Gallo L, Li H, Ruiz W, Hallows K, Apodaca G. A1 adenosine receptor-stimulated exocytosis in bladder umbrella cells requires phosphorylation of ADAM17 Ser-811 and EGF receptor transactivation. Mol Biol Cell. 2014;25:3798-812 pubmed publisher
..We conclude that adenosine-stimulated exocytosis requires PKC- and ADAM17-dependent EGFR transactivation and that the function of ADAM17 in this pathway depends on the phosphorylation state of Ser-811 in its cytoplasmic domain. ..
Gallo L, Dalghi M, Clayton D, Ruiz W, Khandelwal P, Apodaca G. RAB27B requirement for stretch-induced exocytosis in bladder umbrella cells. Am J Physiol Cell Physiol. 2017;:ajpcell.00218.2017 pubmed publisher
..We conclude that RAB27B, but not RAB27A, regulates DFV exocytosis in bladder umbrella cells in a manner that may be parallel to the previously described RAB11A-RAB8A-MYO5B pathway...