A E Aplin

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi Cell adhesion molecules, signal transduction and cell growth
    A E Aplin
    Department of Pharmacology, School of Medicine, University of North Carolina, NC 27599, USA
    Curr Opin Cell Biol 11:737-44. 1999
  2. pmc Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1
    A E Aplin
    Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    J Cell Biol 153:273-82. 2001
  3. pmc Regulation of nucleocytoplasmic trafficking by cell adhesion receptors and the cytoskeleton
    A E Aplin
    Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Cell Biol 155:187-91. 2001
  4. ncbi Integrin and cytoskeletal regulation of growth factor signaling to the MAP kinase pathway
    A E Aplin
    Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Cell Sci 112:695-706. 1999
  5. pmc Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts
    T H Lin
    Department of Pharmacology, University of North Carolina, Chapel Hill 27599, USA
    J Cell Biol 136:1385-95. 1997
  6. ncbi Anchorage-dependent regulation of the mitogen-activated protein kinase cascade by growth factors is supported by a variety of integrin alpha chains
    A E Aplin
    Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    J Biol Chem 274:31223-8. 1999
  7. ncbi Integrin regulation of receptor tyrosine kinase and G protein-coupled receptor signaling to mitogen-activated protein kinases
    R L Juliano
    Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599-7365, USA
    Methods Enzymol 333:151-63. 2001

Collaborators

Detail Information

Publications7

  1. ncbi Cell adhesion molecules, signal transduction and cell growth
    A E Aplin
    Department of Pharmacology, School of Medicine, University of North Carolina, NC 27599, USA
    Curr Opin Cell Biol 11:737-44. 1999
    ..These actions appear to depend on the ability of CAMs to initiate the formation of organized structures that permit the efficient flow of information...
  2. pmc Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1
    A E Aplin
    Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    J Cell Biol 153:273-82. 2001
    ..These data show that integrin-mediated organization of the actin cytoskeleton regulates localization of activated ERK, and in turn the ability of ERK to efficiently phosphorylate nuclear substrates...
  3. pmc Regulation of nucleocytoplasmic trafficking by cell adhesion receptors and the cytoskeleton
    A E Aplin
    Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Cell Biol 155:187-91. 2001
    ..Cell adhesion molecule control of nucleocytoplasmic trafficking allows adhesion to influence many cell decisions, and highlights the diversity of nuclear import and export mechanisms...
  4. ncbi Integrin and cytoskeletal regulation of growth factor signaling to the MAP kinase pathway
    A E Aplin
    Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Cell Sci 112:695-706. 1999
    ....
  5. pmc Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts
    T H Lin
    Department of Pharmacology, University of North Carolina, Chapel Hill 27599, USA
    J Cell Biol 136:1385-95. 1997
    ..These results strongly suggest that integrin-mediated activation of MAP kinase is independent of FAK and indicate the probable existence of at least two distinct integrin signaling pathways in fibroblasts...
  6. ncbi Anchorage-dependent regulation of the mitogen-activated protein kinase cascade by growth factors is supported by a variety of integrin alpha chains
    A E Aplin
    Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    J Biol Chem 274:31223-8. 1999
    ....
  7. ncbi Integrin regulation of receptor tyrosine kinase and G protein-coupled receptor signaling to mitogen-activated protein kinases
    R L Juliano
    Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599-7365, USA
    Methods Enzymol 333:151-63. 2001
    ..Harsh treatment of cells, for example, prolonged suspension culture, may result in irreversible nonphysiological effects in some types of cells...