Research Topics
| Christian C ApfelSummaryAffiliation: University of California Country: USA Publications
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Publications
Intravenous acetaminophen reduces postoperative nausea and vomiting: A systematic review and meta-analysisChristian C Apfel
Department of Anesthesia and Perioperative Care, UCSF Medical Center at Mt Zion, San Francisco, CA, USA Department of Epidemiology and Biostatistics, UCSF Medical Center at Mt Zion, San Francisco, CA, USA Electronic address
Pain 154:677-89. 2013..66, 0.47-0.93), but not with reduction in postoperative opioids (odds ratio 0.89, 0.64-1.22). Prophylactically administered i.v. acetaminophen reduced PONV, mainly mediated through superior pain control...- Evidence-based analysis of risk factors for postoperative nausea and vomitingC C Apfel
Perioperative Clinical Research Core, Department of Anaesthesia and Perioperative Care, UCSF Medical Centre at Mt Zion, University of California San Francisco, 1600 Divisadero, San Francisco, CA 94115, USA
Br J Anaesth 109:742-53. 2012..st> In assessing a patient's risk for postoperative nausea and vomiting (PONV), it is important to know which risk factors are independent predictors, and which factors are not relevant for predicting PONV... 
Who is at risk for postdischarge nausea and vomiting after ambulatory surgery?Christian C Apfel
Epidemiology and Biostatistics, Mt Zion Medical Center, San Francisco General Hospital, Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California 94115, USA
Anesthesiology 117:475-86. 2012..Fortunately, risk scores have been developed to better manage this outcome in hospitalized patients, but there is currently no risk score for postdischarge nausea and vomiting (PDNV) in ambulatory surgical patients...- Transdermal scopolamine for the prevention of postoperative nausea and vomiting: a systematic review and meta-analysisChristian C Apfel
Perioperative Clinical Research Core, Department of Anesthesia and Perioperative Care, University of California at San Francisco, San Francisco, California 94115, USA or
Clin Ther 32:1987-2002. 2010.... - Prevention of postdural puncture headache after accidental dural puncture: a quantitative systematic reviewC C Apfel
Perioperative Clinical Research Core, Department of Anesthesia and Perioperative Care, University of California at San Francisco, 1600 Divisadero St, San Francisco, CA, USA
Br J Anaesth 105:255-63. 2010..Thus, a large multicentre RCT is needed to determine the best preventative practices... - Droperidol has comparable clinical efficacy against both nausea and vomitingC C Apfel
Clinical Research Core, Department of Anesthesia and Perioperative Care, UCSF Mount Zion Hospital, University of California San Francisco, 1600 Divisadero Street, C 447, San Francisco, CA 94115, USA
Br J Anaesth 103:359-63. 2009..This may be relevant for clinical decisions, especially for designing multiple-drug antiemetic regimens... - Neurokinin-1 and novel serotonin antagonists for postoperative and postdischarge nausea and vomitingElizabeth George
Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California 94115, USA
Curr Opin Anaesthesiol 23:714-21. 2010..Finally, we will discuss strategies for prophylaxis and treatment of PONV and PDNV that address the unique concerns in ambulatory surgery patients... 
Restoration of disk height through non-surgical spinal decompression is associated with decreased discogenic low back pain: a retrospective cohort studyChristian C Apfel
Perioperative Clinical Research Core, Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California, USA
BMC Musculoskelet Disord 11:155. 2010....- Pharmacologic management of postoperative nausea and vomitingKatherine E Fero
University of California, UCSF Medical Center, Department of Anesthesia and Perioperative Care, Mount Zion Campus, 1600 Divisadero, C 447, San Francisco, CA 94115, USA
Expert Opin Pharmacother 12:2283-96. 2011..If a patient has 0, 1, 2, 3 or 4 of the four risk factors, we apply a similar number of antiemetic strategies... - Nausea and vomiting after office-based anesthesiaKerstin Kolodzie
Perioperative Clinical Research Core, Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California 94115, USA
Curr Opin Anaesthesiol 22:532-8. 2009..This article reviews the incidences and risk factors for PDNV as well as medications and concepts for prophylaxis and treatment... - Prevention of pain on injection of propofol: systematic review and meta-analysisLeena Jalota
Department of Anesthesia and Perioperative Care, University of California at San Francisco, San Francisco, 94115 CA, USA
BMJ 342:d1110. 2011..To systematically determine the most efficacious approach for preventing pain on injection of propofol... - Effect of increased body mass index and anaesthetic duration on recovery of protective airway reflexes after sevoflurane vs desfluraneR E McKay
Department of Anaesthesia and Perioperative Care, C 450, University of California San Francisco, San Francisco, CA 94143 0648, USA
Br J Anaesth 104:175-82. 2010..Increased BMI may increase the body's capacity to store potent inhaled anaesthetics, more so with more soluble agents. Accordingly, we asked whether increased BMI and longer anaesthesia prolonged airway reflex recovery... - The unrecognised difficult extubation: a call for vigilanceJ Antoine
Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, CA, USA
Anaesthesia 65:946-8. 2010.... - The effect of postoperative fasting on vomiting in children and their assessment of painOliver C Radke
Perioperative Clinical Research Core, Department of Anesthesia and Perioperative Care, University of California at San Francisco, UCSF Medical Center at Mount Zion, San Francisco, CA 94115, USA
Paediatr Anaesth 19:494-9. 2009..Mandatory postoperative food intake has been shown to increase nausea and vomiting, and so postoperative fasting has become common practice even if patients request food or drink... - The role of neurokinin-1 receptor antagonists for the management of postoperative nausea and vomitingChristian C Apfel
Perioperative Clinical Research Core, Department of Anesthesiology and Perioperative Care, University of California, San Francisco, California, USA
Curr Opin Anaesthesiol 21:427-32. 2008..To review the characteristics of neurokinin-1 receptor antagonists and their potential role in the management of postoperative nausea and vomiting... - An admission bioclinical score to predict 1-year outcomes in patients undergoing aneurysm coilingVincent Degos
Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94110, USA
Stroke 43:1253-9. 2012..Our goal was to develop, compare, and validate a predictive score for 1-year outcomes in patients with coiled subarachnoid hemorrhage... - [Nausea and vomiting in the postoperative phase. Expert- and evidence-based recommendations for prophylaxis and therapy]C C Apfel
Perioperative Clinical Research Core, Department of Anesthesia and Perioperative Care, University of California, San Francisco, UCSF Medical Center at Mt Zion, 1600 Divisadero, C 355, San Francisco, California 94115 1605, USA
Anaesthesist 56:1170-80. 2007..These algorithms should provide evidence-based guidelines allowing the development of SOPs/policies which take local circumstances into account...