Research Topics
| Rajender R AparasuSummaryAffiliation: University of Houston Country: USA Publications
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Detail Information
Publications
Hospitalization risk associated with typical and atypical antipsychotic use in community-dwelling elderly patientsRajender R Aparasu
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, Houston, Texas 77030, USA
Am J Geriatr Pharmacother 6:198-204. 2008..However, few studies have examined the impact of typical and atypical antipsychotic use on all-cause hospitalization in the elderly population...
Hypertension management in outpatient visits by diabetic patientsRajender R Aparasu
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, 1441 Moursund Street, Houston, TX 77030, USA
Res Social Adm Pharm 4:284-91. 2008....
Patterns and determinants of antipsychotic prescribing in children and adolescents, 2003-2004Rajender R Aparasu
College of Pharmacy, University of Houston, Houston, TX 77030, USA
Curr Med Res Opin 23:49-56. 2007..This study examined patterns and determinants of antipsychotic prescribing in children and adolescents receiving outpatient care in the United States...
Antipsychotic use and expenditure in the United StatesRajender R Aparasu
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, 1441 Moursund Street, Houston, TX 77030, USA
Psychiatr Serv 57:1693. 2006
Antipsychotic drug use among elderly nursing home residents in the United StatesPravin Kamble
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Houston, Texas 77030, USA
Am J Geriatr Pharmacother 6:187-97. 2008..However, few studies have examined antipsychotic utilization patterns in nursing home residents in the United States since the introduction of atypical agents in the 1990s...
Antihypertensive drug use and the risk of dementia in patients with diabetes mellitusMichael L Johnson
Department of Clinical Sciences and Administration, Division of Pharmacy Administration and Public Health, University of Houston, College of Pharmacy, TX, USA
Alzheimers Dement 8:437-44. 2012..Diabetes and hypertension are independent risk factors for dementia, and hypertension may increase this risk in patients with diabetes. It is unclear whether antihypertensive drugs are associated with risk of dementia in these patients...
Risk of falls and fractures in older adults using atypical antipsychotic agents: a propensity score-adjusted, retrospective cohort studySatabdi Chatterjee
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, Houston, Texas, USA
Am J Geriatr Pharmacother 10:83-94. 2012..However, none of the studies assessed the comparative safety profiles of atypical agents with respect to falls and fractures...
Concomitant antipsychotic prescribing in US outpatient settingsRajender R Aparasu
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, 1441 Moursund Street, Texas Medical Center, Houston, TX 77030, USA
Res Social Adm Pharm 5:234-41. 2009..Clinicians use concomitant antipsychotic therapy for management of psychotic disorders despite a paucity of evidence for this practice...
Prevalence and predictors of anticholinergic agents in elderly outpatients with dementiaRituparna Bhattacharya
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, USA
Am J Geriatr Pharmacother 9:434-41. 2011..Anticholinergic medications, although frequently used in elderly populations, are associated with cognitive impairment and constitute significant concern for patients with dementia...
Determinants of atypical antipsychotic use among antipsychotic users in community-dwelling elderly, 1996-2004Elda Jano
College of Pharmacy, University of Houston, Texas Medical Center, Houston, TX 77030, USA
Curr Med Res Opin 24:709-16. 2008..This study examined the determinants of atypical antipsychotic use among antipsychotic users in community-dwelling elderly in the United States...
Risk of cerebrovascular adverse events in older adults using antipsychotic agents: a propensity-matched retrospective cohort studySandhya Mehta
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, Houston 77030 3407, USA
J Clin Psychiatry 71:689-98. 2010..To compare the risk of cerebrovascular adverse events with second-generation antipsychotic users versus those taking first-generation antipsychotics in community-dwelling older adults...
Risk of death in dual-eligible nursing home residents using typical or atypical antipsychotic agentsRajender R Aparasu
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, 1441 Moursund Street, Houston, TX 77030 3407, USA
Med Care 50:961-9. 2012..Antipsychotic use among dual-eligible nursing home residents is a concern for cost and safety considerations...
Use of antipsychotics among elderly nursing home residents with dementia in the US: an analysis of National Survey DataPravin Kamble
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, Houston, Texas, USA
Drugs Aging 26:483-92. 2009..However, recent data suggest that the risk of adverse effects may offset the benefits of atypical agents in patients with dementia...
Risk factors for dementia in patients over 65 with diabetesNiraj M Parikh
College of Pharmacy, University of Houston, TX, USA
Int J Geriatr Psychiatry 26:749-57. 2011..This study identified factors in patients with diabetes associated with risk of developing dementia...
Extent of functional impairment in children and adolescents with depressionSaurabh Nagar
University of Houston, Texas Medical Center, Houston, TX 77030 3407, USA
Curr Med Res Opin 26:2057-64. 2010..This study examined the extent of functional impairment in children and adolescents aged 5 to 17 years with depression based on 2005-2006 Medical Expenditure Panel Survey (MEPS) data...
Risk of falls and fractures in older adults using antipsychotic agents: a propensity-matched retrospective cohort studySandhya Mehta
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, Houston, Texas 77030 3407, USA
Drugs Aging 27:815-29. 2010..Very few studies have compared the risk of falls and fractures among older adults using typical and atypical agents and none of the studies have evaluated differential risk across antipsychotic classes...
Antipsychotic utilization and expenditure trends among elderly personsElda Jano
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, 1441 Moursund St, Houston, TX 77030-3407, USA
Psychiatr Serv 58:1400. 2007
Risk of serious cardiac events in older adults using antipsychotic agentsSandhya Mehta
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, Houston, USA
Am J Geriatr Pharmacother 9:120-32. 2011..Few epidemiologic studies have evaluated the risk of serious cardiovascular-related events in typical and atypical antipsychotic users...
Effect of certain angiotensin-converting enzyme inhibitors on mortality in heart failure: a multiple-propensity analysisAbhishek S Chitnis
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, 1441 Moursund St, Houston, TX, USA
Res Social Adm Pharm 8:145-56. 2012..There is a substantial evidence about efficacy of angiotensin-converting enzyme inhibitors (ACEIs) in heart failure (HF); however, there is no conclusive evidence on the relative effectiveness of individual ACEIs...
Healthcare outcomes associated with beers' criteria: a systematic reviewElda Jano
College of Pharmacy, University of Houston, Texas Medical Center, Houston, TX 77030, USA
Ann Pharmacother 41:438-47. 2007..To examine healthcare outcomes associated with Beers' criteria of inappropriate medication use based on a literature review...
U.S. national trends in the use of antipsychotics during office visits, 1998-2002Rajender R Aparasu
Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota State University, Brookings, SD 57007, USA
Ann Clin Psychiatry 17:147-52. 2005..There is a paucity of studies on U.S. national trends in the use of antipsychotic medications in the 21st century. This study examined national trends in the prescribing of antipsychotic drugs in office-based physician practices...
Prevalence and predictors of anticholinergic medication use in elderly nursing home residents with dementia: analysis of data from the 2004 National Nursing Home SurveySatabdi Chatterjee
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, Houston, Texas 77030, USA
Drugs Aging 27:987-97. 2010..However, evidence suggests that these medications are associated with significant adverse effects and may lead to worsening of cognitive impairment, particularly in elderly patients with dementia...
Comparative Risk of Cerebrovascular Adverse Events in Community-Dwelling Older Adults using Risperidone, Olanzapine and Quetiapine : A Multiple Propensity Score-Adjusted Retrospective Cohort StudySatabdi Chatterjee
Department of Clinical Sciences and Administration, College of Pharmacy, Texas Medical Center, University of Houston, 1441 Moursund Street, Houston, TX, 77030, USA
Drugs Aging 29:807-17. 2012..However, limited evidence exists regarding comparative cerebrovascular profiles of individual atypical agents, particularly in community settings...
Risk of pneumonia in elderly nursing home residents using typical versus atypical antipsychoticsRajender R Aparasu
College of Pharmacy, University of Houston, Texas Medical Center
Ann Pharmacother 47:464-74. 2013..Prior research suggests that pneumonia is one of the common causes of anti psychotic-related mortality in this population. None of the studies compared typical and atypical antipsychotics with respect to pneumonia...
Prevalence, correlates, and associated outcomes of potentially inappropriate psychotropic use in the community-dwelling elderlyRajender R Aparasu
College of Pharmacy, South Dakota State University, Brookings, South Dakota 57007, USA
Am J Geriatr Pharmacother 2:102-11. 2004..However, there is limited information at the national level on potentially inappropriate psychotropic use, the characteristics of elderly persons at risk, and the impact of this inappropriate use on health care outcomes...
Application of the nonlinear Blinder-Oaxaca decomposition to study racial/ethnic disparities in antiobesity medication use in the United StatesHemalkumar B Mehta
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, 1441 Moursund St, Houston, TX 77030, USA
Res Social Adm Pharm 9:13-26. 2013..The present study demonstrates the use of this method for categorical variables by addressing antiobesity medication use disparity...
Polypharmacy trends in office visits by the elderly in the United States, 1990 and 2000Rajender R Aparasu
College of Pharmacy, Box 2202 C, 1 Administration Lane, South Dakota State University, Brookings, SD 57007, USA
Res Social Adm Pharm 1:446-59. 2005..Within the United States, few studies have examined polypharmacy trends in the elderly population and even fewer studies addressed those at-risk for polypharmacy...
Interaction between selective serotonin reuptake inhibitors and nonsteroidal antiinflammatory drugs: review of the literatureJane R Mort
Department of Pharmacy Practice, College of Pharmacy, South Dakota State University, Brookings, South Dakota 57007-0099, USA
Pharmacotherapy 26:1307-13. 2006..Clinicians must take care to avoid these negative outcomes by altering NSAID or SSRI therapy, or by providing ulcer-protective drugs...
Psychotropic prescription use by community-dwelling elderly in the United StatesRajender R Aparasu
College of Pharmacy, South Dakota State University, Brookings 57007, USA
J Am Geriatr Soc 51:671-7. 2003..To examine psychotropic prescription use in community-dwelling elderly in the United States and its association with predisposing, enabling, and need factors...
Prescribing of psychotropics in the elderly: why is it so often inappropriate?Jane R Mort
College of Pharmacy, South Dakota State University, Rapid City, South Dakota 57701, USA
CNS Drugs 16:99-109. 2002..More research specifically focused on the causes of inappropriate psychotropic medication use and methods to avoid this practice is needed before targeted recommendations can be made...
Antipsychotic prescribing trends among youths, 1997-2002Rajender R Aparasu
South Dakota State University College of Pharmacy, Box 2202 C, 1 Administration Lane, Brookings, South Dakota 57007, USA
Psychiatr Serv 56:904. 2005
The quality of pharmaceutical care in the elderlyRajender R Aparasu
S D J Med 57:489-90. 2004
