Hoda Anton-Culver

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Kids, adolescents, and young adult cancer study-a methodologic approach in cancer epidemiology research
    Nancy J Link
    Department of Epidemiology, School of Medicine, University of California, Irvine, 224 Irvine Hall, Irvine, CA 92697, USA
    J Cancer Epidemiol 2009:354257. 2009
  2. pmc Socioeconomic Impacts on Survival Differ by Race/Ethnicity among Adolescents and Young Adults with Non-Hodgkin's Lymphoma
    Erin E Kent
    Department of Epidemiology, University of California, Irvine, CA 92697 7550, USA
    J Cancer Epidemiol 2010:824691. 2010
  3. pmc The association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohort
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Breast Cancer Res 13:R37. 2011
  4. pmc Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study
    Roger L Milne
    Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre CNIO, Madrid, 28029, Spain
    Breast Cancer Res 12:R110. 2010
  5. pmc Germline polymorphisms in SIPA1 are associated with metastasis and other indicators of poor prognosis in breast cancer
    Nigel P S Crawford
    Laboratory of Population Genetics, National Cancer Institute National Institutes of Health, Bethesda, Maryland, USA
    Breast Cancer Res 8:R16. 2006
  6. pmc The Breast Cancer Family Registry: an infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer
    Esther M John
    Clinical and Genetic Epidemiology Research Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland, USA
    Breast Cancer Res 6:R375-89. 2004
  7. pmc Activating mutation in MET oncogene in familial colorectal cancer
    Deborah W Neklason
    Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA
    BMC Cancer 11:424. 2011
  8. ncbi request reprint The Cancer Genetics Network: recruitment results and pilot studies
    Hoda Anton-Culver
    Epidemiology Division, College of Medicine, University of California, Irvine, 92697 7550, USA
    Community Genet 6:171-7. 2003
  9. ncbi request reprint Characteristics of BRCA1 mutations in a population-based case series of breast and ovarian cancer
    H Anton-Culver
    Epidemiology Division, College of Medicine, 224 Irvine Hall, University of California, Irvine, CA 92697 7550, USA
    Eur J Cancer 36:1200-8. 2000
  10. pmc Cancer prevention strategies: use of cancer prevention research registries
    H Anton-Culver
    Department of Medicine, University of California, Irvine, USA
    Environ Health Perspect 103:237-9. 1995

Research Grants

  1. Hereditary Breast Cancer: Genetic and Molecular Studies
    Hoda Anton Culver; Fiscal Year: 2007
  2. Enhanced Single-Visit Cervical Cancer Screening Program
    Hoda Anton Culver; Fiscal Year: 2007
  3. Hereditary Breast Cancer: Genetic and Molecular Studies
    Hoda Anton Culver; Fiscal Year: 2006
  4. UCI UCSD CANCER GENETICS NETWORK
    Hoda Anton Culver; Fiscal Year: 2002
  5. Hereditary Breast Cancer: Genetic and Molecular Studies
    Hoda Anton Culver; Fiscal Year: 2004
  6. UCI UCSD CANCER GENETICS NETWORK
    Hoda Anton Culver; Fiscal Year: 2006
  7. NCI CFRBCCS INFORMATICS CENTER AT UCI
    Hoda Anton Culver; Fiscal Year: 2005
  8. Hereditary Breast Cancer: Genetic and Molecular Studies
    Hoda Anton Culver; Fiscal Year: 2005
  9. CARCR Confrence Support
    Hoda Anton Culver; Fiscal Year: 2005
  10. NCI CANCER GENETICS NETWORK INFORMATICS CENTER AT UCI
    Hoda Anton Culver; Fiscal Year: 2006

Detail Information

Publications73

  1. pmc Kids, adolescents, and young adult cancer study-a methodologic approach in cancer epidemiology research
    Nancy J Link
    Department of Epidemiology, School of Medicine, University of California, Irvine, 224 Irvine Hall, Irvine, CA 92697, USA
    J Cancer Epidemiol 2009:354257. 2009
    ..8% and varies by age and tumor type. The study included patients, mothers, and fathers. The methods used to establish this resource are described, and the values of the resource in studies of childhood and young adult cancer are outlined...
  2. pmc Socioeconomic Impacts on Survival Differ by Race/Ethnicity among Adolescents and Young Adults with Non-Hodgkin's Lymphoma
    Erin E Kent
    Department of Epidemiology, University of California, Irvine, CA 92697 7550, USA
    J Cancer Epidemiol 2010:824691. 2010
    ..001). Reduced overall and lymphoma-specific survival was associated with lower SES in AYAs with NHL, although a significant trend was only observed for NHWs...
  3. pmc The association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohort
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Breast Cancer Res 13:R37. 2011
    ..It therefore seems plausible that variation in genes involved in metabolism of these hormones may affect breast cancer risk, and that these associations may vary depending on menopausal status and use of hormone therapy...
  4. pmc Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study
    Roger L Milne
    Genetic and Molecular Epidemiology Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre CNIO, Madrid, 28029, Spain
    Breast Cancer Res 12:R110. 2010
    ....
  5. pmc Germline polymorphisms in SIPA1 are associated with metastasis and other indicators of poor prognosis in breast cancer
    Nigel P S Crawford
    Laboratory of Population Genetics, National Cancer Institute National Institutes of Health, Bethesda, Maryland, USA
    Breast Cancer Res 8:R16. 2006
    ..The aim of this study was to determine whether single nucleotide polymorphisms (SNPs) within the human SIPA1 gene are associated with metastasis and other disease characteristics in breast cancer...
  6. pmc The Breast Cancer Family Registry: an infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer
    Esther M John
    Clinical and Genetic Epidemiology Research Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland, USA
    Breast Cancer Res 6:R375-89. 2004
    ....
  7. pmc Activating mutation in MET oncogene in familial colorectal cancer
    Deborah W Neklason
    Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA
    BMC Cancer 11:424. 2011
    ..Familial colorectal cancer has been linked to chromosome 7q31 by multiple affected relative pair studies. The MET proto-oncogene which resides in this chromosomal region is considered a candidate for genetic susceptibility...
  8. ncbi request reprint The Cancer Genetics Network: recruitment results and pilot studies
    Hoda Anton-Culver
    Epidemiology Division, College of Medicine, University of California, Irvine, 92697 7550, USA
    Community Genet 6:171-7. 2003
    ....
  9. ncbi request reprint Characteristics of BRCA1 mutations in a population-based case series of breast and ovarian cancer
    H Anton-Culver
    Epidemiology Division, College of Medicine, 224 Irvine Hall, University of California, Irvine, CA 92697 7550, USA
    Eur J Cancer 36:1200-8. 2000
    ..The results indicate that, using a conservative approach to targeted genotyping of BRCA1, the frequency of mutations was consistent with those reported using similar methods of population-based case ascertainment...
  10. pmc Cancer prevention strategies: use of cancer prevention research registries
    H Anton-Culver
    Department of Medicine, University of California, Irvine, USA
    Environ Health Perspect 103:237-9. 1995
    ..Regardless of what we do in the future, we must now promote healthier lifestyles, prevent exposure to known carcinogens, and improve early detection procedures...
  11. pmc Meat consumption, nonsteroidal anti-inflammatory drug use, and mortality among colorectal cancer patients in the California Teachers Study
    Jason A Zell
    Genetic Epidemiology Research Institute, Department of Epidemiology, University of California at Irvine, 92697, USA
    Cancer Prev Res (Phila) 3:865-75. 2010
    ..These findings have implications for CRC survivorship and tertiary CRC prevention...
  12. ncbi request reprint Prognostic factors for survival of stage I nonsmall cell lung cancer patients : a population-based analysis of 19,702 stage I patients in the California Cancer Registry from 1989 to 2003
    S H Ignatius Ou
    Division of Hematology Oncology, Department of Medicine, Chao Family Comprehensive Cancer Center, Orange, California 92868, USA
    Cancer 110:1532-41. 2007
    ....
  13. ncbi request reprint Validation of the proposed International Association for the Study of Lung Cancer non-small cell lung cancer staging system revisions for advanced bronchioloalveolar carcinoma using data from the California Cancer Registry
    Jason A Zell
    Genetic Epidemiology Research Institute, Department of Epidemiology, University of California Irvine, Irvine, California, USA
    J Thorac Oncol 2:1078-85. 2007
    ..We set out to validate this staging system for bronchioloalveolar carcinoma (BAC) cases using data from the California Cancer Registry (CCR)...
  14. ncbi request reprint Risk of pancreatic adenocarcinoma: disparity between African Americans and other race/ethnic groups
    Kenneth J Chang
    Division of Gastroenterology, Department of Medicine, University of California, Irvine Medical Center, Orange, California 92868 3298, USA
    Cancer 103:349-57. 2005
    ..African Americans have a higher incidence of pancreatic adenocarcinoma compared with non-Hispanic whites. Whether other clinical differences exist between these two groups is not well known...
  15. ncbi request reprint Race, socioeconomic status, treatment, and survival time among pancreatic cancer cases in California
    Jason A Zell
    Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, University of California, Irvine Medical Center, 101 The City Drive South, Orange, CA 92868, USA
    Cancer Epidemiol Biomarkers Prev 16:546-52. 2007
    ..We set out to determine this using the large, population-based California Cancer Registry (CCR) database as a model...
  16. ncbi request reprint Misclassification of bronchioloalveolar carcinoma with cytologic diagnosis of lung cancer
    Dan J Raz
    Department of Surgery, Division of Cardiothoracic Surgery and the UCSF Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94131, USA
    J Thorac Oncol 1:943-8. 2006
    ..The aims of this study were to calculate the sensitivity and specificity of cytologic diagnosis of BAC and to estimate the misclassification of BAC as other subtypes of NSCLC...
  17. ncbi request reprint Feasibility of management of high-grade cervical lesions in a single visit: a randomized controlled trial
    Wendy R Brewster
    Department of Medicine, School of Medicine, University of California, Irvine 92868 3200, USA
    JAMA 294:2182-7. 2005
    ..Screening has been shown to reduce cervical cancer incidence rates...
  18. ncbi request reprint Aurora-A/STK15 T+91A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types
    Amanda Ewart-Toland
    UCSF Comprehensive Cancer Center, University of California, San Francisco, CA 94115, USA
    Carcinogenesis 26:1368-73. 2005
    ..The data also underline the advantages of comparative association studies involving study populations from different ethnic groups for determination of disease risk...
  19. ncbi request reprint Epidemiology of bronchioloalveolar carcinoma: improvement in survival after release of the 1999 WHO classification of lung tumors
    Jason A Zell
    The Chao Family Comprehensive Cancer Center, Division of Hematology, Department of Medicine, University of California, Irvine, CA, USA
    J Clin Oncol 23:8396-405. 2005
    ..Classification changes for bronchioloalveolar carcinoma (BAC) by the WHO in May 1999 narrowed its definition. This study was undertaken in an attempt to characterize the impact of these changes on the epidemiology of BAC...
  20. pmc A unique gender difference in early onset melanoma implies that in addition to ultraviolet light exposure other causative factors are important
    Feng Liu
    Department of Medicine, University of California, Irvine, CA, USA
    Pigment Cell Melanoma Res 26:128-35. 2013
    ..We conclude that exposure to solar ultraviolet (UV) radiation is the major causative factor for melanoma at older age (>44 yr), but that other factors may play a role in early onset melanomas, particularly in females...
  21. pmc Associations of a polymorphism in the ornithine decarboxylase gene with colorectal cancer survival
    Jason A Zell
    Department of Epidemiology, University of California, Irvine, California 92697, USA
    Clin Cancer Res 15:6208-16. 2009
    ..We examined associations of the +316 ODC1 single nucleotide polymorphism (SNP) with colorectal cancer-specific survival among colorectal cancer cases, and then investigated its functional significance in colon cancer cells...
  22. ncbi request reprint Increased incidence of squamous cell anal cancer among men with AIDS in the era of highly active antiretroviral therapy
    Catherine Diamond
    Department of Medicine, Epidemiology Division, University of California Irvine, Orange, California 92868, USA
    Sex Transm Dis 32:314-20. 2005
    ..We sought to determine if the introduction of highly active antiretroviral therapy (HAART) corresponded with changes in anal squamous cell cancer rates among men with AIDS...
  23. ncbi request reprint Improved survival and chemotherapy response among patients with AIDS-related non-Hodgkin's lymphoma receiving highly active antiretroviral therapy
    Catherine Diamond
    University of California, Irvine Department of Medicine, CA, USA
    Hematol Oncol 24:139-45. 2006
    ..We conclude that HAART should be initiated or continued after NHL diagnosis, including during the period of chemotherapy administration...
  24. pmc Hypertension, antihypertensive medication use, and breast cancer risk in the California Teachers Study cohort
    Joan A Largent
    Department of Epidemiology, College of Health Sciences, University of California Irvine, Irvine, CA 92697 7555, USA
    Cancer Causes Control 21:1615-24. 2010
    ..We investigated the association between hypertension, antihypertensive (AH) medication use, and breast cancer in a large prospective study, the California Teachers Study (CTS)...
  25. doi request reprint Survival for patients with invasive cutaneous melanoma among ethnic groups: the effects of socioeconomic status and treatment
    Jason A Zell
    Division of Hematology Oncology, Department of Internal Medicine, Chao Family Comprehensive Cancer Center, University of California, Irvine 92697, USA
    J Clin Oncol 26:66-75. 2008
    ..We set out to determine this by using the large, population-based California Cancer Registry (CCR) database as a model...
  26. ncbi request reprint Differential effects of wine consumption on colorectal cancer outcomes based on family history of the disease
    Jason A Zell
    Genetic Epidemiology Research Institute, University of California UC Irvine, Irvine, CA 92697, USA
    Nutr Cancer 59:36-45. 2007
    ..50, 95% confidence interval = 0.25-0.99). Our findings implicate favorable effects of wine consumption on stage at presentation and survival in CRC, selectively among familial CRC cases...
  27. ncbi request reprint Natural history of stage I non-small cell lung cancer: implications for early detection
    Dan J Raz
    University of California, San Francisco, 513 Parnassus Ave, S 321, San Francisco, CA 94131, USA
    Chest 132:193-9. 2007
    ..Our hypothesis is that long-term survival in patients with untreated stage I non-small cell lung cancer (NSCLC) is uncommon...
  28. ncbi request reprint How valid is using cancer registries' data to identify acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma?
    Catherine Diamond
    Department of Medicine, UCI Medical Center, University of California Irvine, Orange, CA 92868, USA
    Cancer Causes Control 18:135-42. 2007
    ..We sought to determine the accuracy of cancer registry data regarding the human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) status of patients with non-Hodgkin's lymphoma (NHL)...
  29. doi request reprint Delay in surgical treatment and survival after breast cancer diagnosis in young women by race/ethnicity
    Erlyn C Smith
    Department of Epidemiology, University of California, Irvine, CA 92697, USA
    JAMA Surg 148:516-23. 2013
    ..Five-year survival rates are lowest for AYA women, and only a few studies have examined the impact of delay in treatment, race/ethnicity, and other socioeconomic factors on survival in AYA women...
  30. ncbi request reprint Changes in acquired immunodeficiency syndrome-related non-Hodgkin lymphoma in the era of highly active antiretroviral therapy: incidence, presentation, treatment, and survival
    Catherine Diamond
    Department of Medicine, Divisions of Epidemiology and Infectious Diseases, University of California Irvine, Irvine, California 92868, USA
    Cancer 106:128-35. 2006
    ..The authors sought to determine whether the availability of highly active antiretroviral therapy (HAART) coincided with changes in the epidemiology of acquired immunodeficiency syndrome (AIDS)-related non-Hodgkin lymphoma (NHL)...
  31. ncbi request reprint Low allele frequency of MLH1 D132H in American colorectal and endometrial cancer patients
    Brian Y Shin
    Division of Hematology Oncology, Department of Medicine, University of California Irvine, 92697, USA
    Dis Colon Rectum 48:1723-7. 2005
    ....
  32. doi request reprint Low socioeconomic status is a poor prognostic factor for survival in stage I nonsmall cell lung cancer and is independent of surgical treatment, race, and marital status
    S H Ignatius Ou
    Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Department of Medicine, University of California Irvine Medical Center, Orange, CA 92868 3298, USA
    Cancer 112:2011-20. 2008
    ..In this study, the authors investigated the role of SES in this survival disparity among patients with stage I NSCLC...
  33. pmc Leukemia survival in children, adolescents, and young adults: influence of socioeconomic status and other demographic factors
    Erin E Kent
    Department of Epidemiology, University of California, Irvine, 224 Irvine Hall, Irvine, CA 92697 7555, USA
    Cancer Causes Control 20:1409-20. 2009
    ..We explored the relationship between SES and survival as modified by age and race/ethnicity using data from the California Cancer Registry...
  34. ncbi request reprint Reproductive history and risk of second primary breast cancer: the WECARE study
    Joan A Largent
    Epidemiology Division, Department of Medicine, University of California, Irvine, Irvine, CA 92697 7555, USA
    Cancer Epidemiol Biomarkers Prev 16:906-11. 2007
    ..Women with an initial breast cancer diagnosis are at elevated risk of developing subsequent cancer in the contralateral breast. Studies of reproductive factors and contralateral breast cancer (CBC) have provided inconsistent results...
  35. ncbi request reprint Presentation and outcomes of systemic non-Hodgkin's lymphoma: a comparison between patients with acquired immunodeficiency syndrome (AIDS) treated with highly active antiretroviral therapy and patients without AIDS
    Catherine Diamond
    Department of Medicine, University of California Irvine, 101 The City Drive, Orange, CA 92868, USA
    Leuk Lymphoma 47:1822-9. 2006
    ....
  36. pmc Risk of second primary cancer in men with breast cancer
    Sacha Satram-Hoang
    Epidemiology Division, School of Medicine, University of California, Irvine, CA 92697, USA
    Breast Cancer Res 9:R10. 2007
    ..A retrospective registry-based cohort study was conducted to examine the risk of second primary cancer following the occurrence of breast cancer in males...
  37. ncbi request reprint Survival improvements for advanced stage nonbronchioloalveolar carcinoma-type nonsmall cell lung cancer cases with ipsilateral intrapulmonary nodules
    Jason A Zell
    Division of Hematology Oncology, Department of Medicine, Chao Family Comprehensive Cancer Center, University of California at Irvine School of Medicine, Irvine, California 92697, USA
    Cancer 112:136-43. 2008
    ..However, it is not known whether these differences are observed in patients with non-BAC NSCLC...
  38. ncbi request reprint Prognostic significance of the non-size-based AJCC T2 descriptors: visceral pleura invasion, hilar atelectasis, or obstructive pneumonitis in stage IB non-small cell lung cancer is dependent on tumor size
    Sai Hong Ignatius Ou
    Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Department of Medicine, University of California Irvine Medical Center, Orange, CA 92868 3298, USA
    Chest 133:662-9. 2008
    ..The T2 descriptor for staging non-small cell lung cancer (NSCLC) contains several non-size-based criteria. It remains unknown whether the prognostic significance of these non-size-based criteria is dependent on tumor size...
  39. pmc Effect of reproductive factors on stage, grade and hormone receptor status in early-onset breast cancer
    Joan A Largent
    Epidemiology Division, Department of Medicine, University of California, Irvine, California, USA
    Breast Cancer Res 7:R541-54. 2005
    ..The objective of the present study was to examine the relationship between reproductive events and tumor stage, grade, estrogen receptor and progesterone receptor status, and survival in women diagnosed with early-onset breast cancer...
  40. pmc The association of body mass index with mortality in the California Teachers Study
    Leona Bessonova
    Department of Epidemiology, School of Medicine, University of California, Irvine, CA 92697 7550, USA
    Int J Cancer 129:2492-501. 2011
    ..These findings help to identify groups at risk for BMI-related poor health outcomes...
  41. doi request reprint Risk of a second breast cancer associated with hormone-receptor and HER2/neu status of the first breast cancer
    Leona Bessonova
    Department of Epidemiology, University of California Irvine, Irvine, CA 92697, USA
    Cancer Epidemiol Biomarkers Prev 20:389-96. 2011
    ..Hormone-receptor (HR) and HER2/neu-receptor (HER2) status of breast tumors are important indicators for targeted therapies. We examine the association of receptor status and risk for a second breast cancer...
  42. ncbi request reprint Malignancies following in situ cervical cancer in Hispanic Americans and non-Hispanic Whites
    Thomas H Taylor
    Epidemiology Division, Department of Medicine, University of California, Irvine, 224 Irvine Hall, Irvine, CA 92697 7550, USA
    Gynecol Oncol 103:1012-6. 2006
    ..Some risk factors for cervical cancer in situ convey risk for malignancies of the cervix and other sites. We estimate risk of several malignancies following in situ cancer of the cervix for Hispanic Americans and non-Hispanic Whites...
  43. ncbi request reprint Highly active antiretroviral therapy is associated with improved survival among patients with AIDS-related primary central nervous system non-Hodgkin's lymphoma
    Catherine Diamond
    University of California, Irvine, Department of Medicine, USA
    Curr HIV Res 4:375-8. 2006
    ..HAART, radiation therapy, and better performance status were associated with improved survival. We conclude that HAART prolongs survival in AIDS-related CNS NHL...
  44. pmc Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women
    Rachel T Palmieri
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Cancer Epidemiol Biomarkers Prev 17:3567-72. 2008
    ..This analysis shows the importance of consortia, like the OCAC, in either confirming or refuting the validity of putative findings in studies with smaller sample sizes. (Cancer Epidemiol Biomarkers Prev 2008;17(12):3567-72)...
  45. doi request reprint "You're too young for this": adolescent and young adults' perspectives on cancer survivorship
    Erin E Kent
    Cancer Prevention Fellowship Program and Office of Cancer Survivorship, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
    J Psychosoc Oncol 30:260-79. 2012
    ..Future intervention development for adolescent and young adult survivors should involve patient voices at each stage of the research process...
  46. pmc Prognostic impact of human epidermal growth factor-like receptor 2 and hormone receptor status in inflammatory breast cancer (IBC): analysis of 2,014 IBC patient cases from the California Cancer Registry
    Jason A Zell
    Department of Epidemiology, Genetic Epidemiology Research Institute, School of Medicine, University of California Irvine, Irvine, CA 92697, USA
    Breast Cancer Res 11:R9. 2009
    ....
  47. pmc Nonsteroidal anti-inflammatory drugs: effects on mortality after colorectal cancer diagnosis
    Jason A Zell
    Genetic Epidemiology Research Institute and Department of Epidemiology, University of California at Irvine, Irvine, California 92697 7550, USA
    Cancer 115:5662-71. 2009
    ..The authors investigated the association between prediagnosis NSAID use and mortality after CRC diagnosis among women in the California Teachers Study cohort...
  48. ncbi request reprint Risk and risk reduction involving arginine intake and meat consumption in colorectal tumorigenesis and survival
    Jason A Zell
    Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA 92697 7550, USA
    Int J Cancer 120:459-68. 2007
    ..Our results suggest important roles for arginine and meat consumption in CRC pathogenesis, and have implications for CRC prevention...
  49. doi request reprint Adherence to treatment guidelines for ovarian cancer as a measure of quality care
    Robert E Bristow
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of California, Irvine Medical Center, Orange, California 92868, USA
    Obstet Gynecol 121:1226-34. 2013
    ....
  50. pmc Quality of life, characteristics and survival of patients with HIV and lymphoma
    Catherine Diamond
    Department of Epidemiology, University of California Irvine, Irvine, CA 92697 7555, USA
    Qual Life Res 19:149-55. 2010
    ..We sought to compare the quality of life (QOL), characteristics, and survival of patients with non-Hodgkin lymphoma (NHL) with and without human immunodeficiency virus (HIV) infection...
  51. ncbi request reprint Quality of life in long-term cervical cancer survivors
    Lari Wenzel
    Department of Medicine and Center for Health Policy Research, University of California Irvine, 111 Academy Way, Suite 220, Irvine, CA 92697 5800, USA
    Gynecol Oncol 97:310-7. 2005
    ..To describe the quality of life (QOL) and long-term psychosocial sequelae of women of childbearing age diagnosed with cervical cancer 5-10 years earlier...
  52. doi request reprint Testing targeted approaches to enhance Cancer Genetics Network minority recruitment within Asian populations
    Lari Wenzel
    Center for Health Policy Research, University of California, Irvine, CA 92697, USA
    Community Genet 11:234-40. 2008
    ..Asian Americans have been underrepresented in cancer research. The purpose of this study was to evaluate the efficacy of a multiple arm recruitment approach in improving Asian recruitment into the Cancer Genetics Network (CGN)...
  53. pmc Genotype determination for polymorphisms in linkage disequilibrium
    Zhaoxia Yu
    Department of Statistics, University of California, Irvine, CA, USA
    BMC Bioinformatics 10:63. 2009
    ..Although many statistical methods have been developed to improve either genotype calling or imputation of missing genotypes, treating the two steps independently can lead to loss of genetic information...
  54. pmc Gender and race/ethnicity affect the cost-effectiveness of colorectal cancer screening
    Charles P Theuer
    Department of Surgery, University of California, Irvine, 224 Irvine Hall, Irvine, CA 92697 7550, USA
    J Natl Med Assoc 98:51-7. 2006
    ..We determined the influence of gender and race/ethnicity on the cost-effectiveness of recommended colorectal cancer screening regimens...
  55. ncbi request reprint Prevalence and clinical correlates of isolated mitral, isolated aortic regurgitation, and both in adults aged 21 to 35 years (from the CARDIA study)
    Cheryl L Reid
    Department of Medicine, Division of Epidemiology, University of California, Irvine, Irvine, California, USA
    Am J Cardiol 99:830-4. 2007
    ..In conclusion, MR and AR detected by color Doppler echocardiography are relatively uncommon in a healthy young adult population, but both are associated with evidence of increased left ventricular dimensions and mass...
  56. ncbi request reprint New perspectives on melanoma pathogenesis and chemoprevention
    Frank L Meyskens
    University of California, Irvine, Orange 92868, USA
    Recent Results Cancer Res 174:191-5. 2007
    ..These observations offer a new paradigm for the development of preventive (and therapeutic) approaches to this disease...
  57. ncbi request reprint Validation of family history data in cancer family registries
    Argyrios Ziogas
    Epidemiology Division, Department of Medicine, University of California Irvine, 224 Irvine Hall, Irvine, CA 92697 7550, USA
    Am J Prev Med 24:190-8. 2003
    ..In this study, we sought to determine the validity of the reporting of family history of cancer by probands in population-based and clinic-based family registries of breast, ovarian, and colorectal cancers...
  58. pmc Survival after colorectal cancer diagnosis is associated with colorectal cancer family history
    Jason A Zell
    Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Department of Medicine, University of California, Irvine, Irvine, CA 92697, USA
    Cancer Epidemiol Biomarkers Prev 17:3134-40. 2008
    ..Our population-based analysis investigates whether familial CRC cases exhibit improved survival compared with sporadic CRC cases...
  59. pmc Pilot study of blood biomarker candidates for detection of pancreatic cancer
    Ru Chen
    GI Division, Department of Medicine, University of Washington, Seattle, WA 98195, USA
    Pancreas 39:981-8. 2010
    ..Biomarkers that detect pancreatic cancer at earlier stages could improve the outcome of this deadly disease...
  60. ncbi request reprint Risk factors for acute myeloid leukemia and multiple myeloma: a combination of GIS and case-control studies
    Steven A Speer
    Epidemiology Division, Department of Medicine, University of California, Irvine, 224 Irvine Hall, Irvine, CA 92697 7550, USA
    J Environ Health 64:9-16; quiz 35-6. 2002
    ..The case-control study identified occupational and lifestyle risk factors for AML and MM that were not apparent from census-tract-level data...
  61. pmc Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium
    Mia M Gaudet
    Department of Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cancer Epidemiol Biomarkers Prev 18:1610-6. 2009
    ....
  62. ncbi request reprint Self-sampling for human papillomavirus in a community setting: feasibility in Hispanic women
    Israel De Alba
    Department of Medicine, School of Medicine, University of California Irvine, Irvine, California, USA
    Cancer Epidemiol Biomarkers Prev 17:2163-8. 2008
    ....
  63. pmc Meat consumption, ornithine decarboxylase gene polymorphism, and outcomes after colorectal cancer diagnosis
    Jason A Zell
    Department of Epidemiology, California, University of California, USA Genetic Epidemiology Research Institute, University of California, Irvine, California, USA Chao Family Comprehensive Cancer Center, University of California, Irvine, California, USA Division of Hematology Oncology, University of California, Irvine, California, USA
    J Carcinog 11:17. 2012
    ..Polymorphism in the polyamine-regulatory gene, ornithine decarboxylase 1 (Odc1, rs2302615) is prognostic for CRC-specific mortality. Here, we examined joint effects of meat consumption and Odc1 polymorphism on CRC-specific mortality...
  64. ncbi request reprint Etiologic pathogenesis of melanoma: a unifying hypothesis for the missing attributable risk
    Frank L Meyskens
    Department of Medicine, Hematology Oncology, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, California
    Clin Cancer Res 10:2581-3. 2004
  65. ncbi request reprint A pilot study of male breast cancer in the Veterans Affairs healthcare system
    Sacha Satram-Hoang
    Division of Epidemiology, School of Medicine, University of California, Irvine, USA
    J Environ Pathol Toxicol Oncol 29:235-44. 2010
    ..We report our findings on a hospital-based retrospective pilot cohort with case-controls study, which we carried out to examine genetic, environmental, and occupational risk factors in men with breast cancer...
  66. pmc The effect of difluoromethylornithine on decreasing prostate size and polyamines in men: results of a year-long phase IIb randomized placebo-controlled chemoprevention trial
    Anne R Simoneau
    Department of Medicine, University of California, Irvine, 101 The City Drive, Route 81, Building 55, Room 304, Orange, CA 92868, USA
    Cancer Epidemiol Biomarkers Prev 17:292-9. 2008
    ..The prostate has high levels of tissue polyamines and has shown sensitivity to DFMO both in vitro and in vivo...
  67. pmc Enhanced Expression of Radiation-induced Leukocyte CDKN1A mRNA in Multiple Primary Breast Cancer Patients: Potential New Marker of Cancer Susceptibility
    Masato Mitsuhashi
    Hitachi Chemical Research Center, Inc, Irvine, CA, USA
    Biomark Insights 4:201-9. 2009
    ..The study also suggests that ex vivo gene expression analysis could potentially be used as a new tool in epidemiological studies for cancer and radiation sensitivity research...
  68. doi request reprint The Athena Breast Health Network: developing a rapid learning system in breast cancer prevention, screening, treatment, and care
    Sarah L Elson
    Department of Surgery, University of California, San Francisco, Box 1710, San Francisco, CA 94143 1710, USA
    Breast Cancer Res Treat 140:417-25. 2013
    ..The Athena Breast Health Network can serve as a model of a rapid learning system that integrates epidemiologic, behavioral, and clinical research with clinical care improvements. ..
  69. pmc Association of single nucleotide polymorphisms of nicotinic acetylcholine receptor subunits with cervical neoplasia
    Itzel Calleja-Macias
    Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA 92697, USA
    Life Sci 91:1099-102. 2012
    ..Recent literature suggests that single nucleotide polymorphisms (SNPs) of some of these subunits, notably alpha5, are risk factors for developing lung cancer in smokers as well as in non-smokers...
  70. doi request reprint Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR)
    Elizabeth C Chao
    Genetic Epidemiology Research Institute, University of California, Irvine, Irvine, California, USA
    Hum Mutat 29:852-60. 2008
    ..MAPP-MMR is an effective bioinformatic tool for missense variant interpretation that accurately distinguishes MLH1/MSH2 deleterious variants from neutral variants...
  71. ncbi request reprint Characteristics and survival of patients with non-Hodgkin's lymphoma with and without acquired immunodeficiency syndrome
    Catherine Diamond
    Department of Medicine, Epidemiology Division, University of California, Irvine 92679, USA
    Hematol Oncol 20:177-87. 2002
    ..001). Although these patients with AIDS-related NHL were unlikely to survive, the highly active antiretroviral agents currently used may improve outcomes in future patients...
  72. ncbi request reprint Dynamical interactions between multiple cancers
    Dominik Wodarz
    Department of Ecology and Evolution, University of California, Irvine, California 92697, USA
    Cell Cycle 4:764-71. 2005
    ..We further discuss the inefficiency of metastatic cells to grow successfully, and suggest an explanation for the occurrence of multiple metastases with an unknown primary cancer...
  73. doi request reprint TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases
    Will Yarosh
    Department of Pediatrics, Division of Human Genetics, University of California, Irvine, California 92697, USA
    Cancer Res 68:693-9. 2008
    ..TBX3 repression to its targets is dependent on HDAC activity. TBX3 may serve as a biomarker for breast cancer and have significant applications in both breast cancer diagnosis and treatment...

Research Grants14

  1. Hereditary Breast Cancer: Genetic and Molecular Studies
    Hoda Anton Culver; Fiscal Year: 2007
    ..abstract_text> ..
  2. Enhanced Single-Visit Cervical Cancer Screening Program
    Hoda Anton Culver; Fiscal Year: 2007
    ..The incremental net cost associated with an incremental improvement in outcomes in terms of quality-adjusted life years (QALYs) will be measured. ..
  3. Hereditary Breast Cancer: Genetic and Molecular Studies
    Hoda Anton Culver; Fiscal Year: 2006
    ..abstract_text> ..
  4. UCI UCSD CANCER GENETICS NETWORK
    Hoda Anton Culver; Fiscal Year: 2002
    ..The majority of the elements of the proposed network have already been established by our group and communications among them are in place. ..
  5. Hereditary Breast Cancer: Genetic and Molecular Studies
    Hoda Anton Culver; Fiscal Year: 2004
    ..abstract_text> ..
  6. UCI UCSD CANCER GENETICS NETWORK
    Hoda Anton Culver; Fiscal Year: 2006
    ..The majority of the elements of the proposed network have already been established by our group and communications among them are in place. ..
  7. NCI CFRBCCS INFORMATICS CENTER AT UCI
    Hoda Anton Culver; Fiscal Year: 2005
    ....
  8. Hereditary Breast Cancer: Genetic and Molecular Studies
    Hoda Anton Culver; Fiscal Year: 2005
    ..abstract_text> ..
  9. CARCR Confrence Support
    Hoda Anton Culver; Fiscal Year: 2005
    ..The March 2005 conference, which is the first to be covered by this proposal, will be held at a still to be determined site in Northern California. ..
  10. NCI CANCER GENETICS NETWORK INFORMATICS CENTER AT UCI
    Hoda Anton Culver; Fiscal Year: 2006
    ..The design of the Cancer Genetics Network CIMS architecture is a very cost-effective solution without compromising performance and scalability and prepares for the challenges of the next millennium. ..