Research Topics
| Thomas AnthonySummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Publications
Report of the clinical protocol committee: development of randomized trials for malignant bowel obstructionThomas Anthony
Department of Surgery, University of Texas, Southwestern Medical Center, and Veterans Affairs North Texas Health Care System, Dallas, Texas 75390 9155, USA
J Pain Symptom Manage 34:S49-59. 2007..The small intestinal trial is designed to compare surgical intervention versus best medical care, whereas the colonic trial seeks to compare surgery with endoscopically-placed intraluminal stents coupled with best medical care...
Transmetatarsal amputation: assessment of current selection criteriaThomas Anthony
Section of General Surgery, Surgical Service, VA North Texas Health Care System, 4500 S Lancaster Rd, Dallas, TX 75216, USA
Am J Surg 192:e8-11. 2006..The purpose of this study was to assess the validity of these selection criteria...
The association of pretreatment health-related quality of life with surgical complications for patients undergoing open surgical resection for colorectal cancerThomas Anthony
University of Texas, Southwestern Medical Center, VA North Texas Health Care System, 4500 S Lancaster Rd, Dallas, TX 75216, USA
Ann Surg 238:690-6. 2003..The purpose of this study was to define the association between pretreatment health-related quality of life (HRQL) and surgical complications for patients with colorectal cancer...
Colorectal cancer follow-up in 2005Thomas Anthony
Division of Surgical Oncology, Department of Surgery, University of Texas, Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
Surg Oncol Clin N Am 15:175-93, viii. 2006....
Assessing outcomes to determine whether symptoms related to hypertension justify renal artery stentingJ Gregory Modrall
Dallas Veterans Affairs Medical Center, University of Texas Southwestern Medical School, Dallas, TX, USA
J Vasc Surg 55:413-9; discussion 419-20. 2012....
Feasibility of a supervised inpatient low-calorie diet program for massive weight loss prior to RYGB in superobese patientsSergio Huerta
Department of Surgery, Dallas VA Medical Center, 4500 Lancaster Road, Dallas, TX 75216, USA
Obes Surg 20:173-80. 2010..This study was undertaken to determine the feasibility of an inpatient low-calorie program for a substantial decrease of preoperative weight (>10 points in BMI) in superobese patients...
In vitro and in vivo radiosensitization of colorectal cancer HT-29 cells by the smac mimetic JP-1201Sergio Huerta
Department of Surgery, University of Texas Southwestern Medical Center Dallas VA Medical Center, Dallas, TX 75216, USA
Surgery 148:346-53. 2010..This study was undertaken to assess the radiosensitizing properties of the smac mimetic JP-1201 in radioresistant HT-29 colorectal cancer cells in vitro and established xenografts in SCID mice...
Evaluating an evidence-based bundle for preventing surgical site infection: a randomized trialThomas Anthony
Department of Surgical Services, Veterans Affairs North Texas Health Care System, 4500 S Lancaster Road, Dallas, TX 75216, USA
Arch Surg 146:263-9. 2011..To determine if an evidence-based practice bundle would result in a significantly lower rate of surgical site infections (SSIs) when compared with standard practice...
The impact of surgical site infection on the development of incisional hernia and small bowel obstruction in colorectal surgeryBryce W Murray
Dallas VA Medical Center, Surgical Services 112, 4500 S Lancaster Road, Dallas, TX 75216, USA
Am J Surg 202:558-60. 2011..The purpose of this study was to evaluate the long-term complications of surgical site infection (SSI) in the colorectal population, specifically its association with incisional hernia and small bowel obstruction...
Correlation between ankle-brachial index, symptoms, and health-related quality of life in patients with peripheral vascular diseaseJoshua Long
Department of Surgery, University of Texas Southwestern Medical Center, USA
J Vasc Surg 39:723-7. 2004..However, neither variable fully expresses patient HRQL. These data suggest that sole reliance on these surrogates may not accurately reflect the effect of PVD on HRQL, or the potential benefit of vascular surgery in improving HRQL...
Clinical and kidney morphologic predictors of outcome for renal artery stenting: data to inform patient selectionJ Gregory Modrall
Dallas Veterans Affairs Medical Center, University of Texas Southwestern Medical Center, Dallas, TX 75390 9157, USA
J Vasc Surg 53:1282-89; discussion 1289-90. 2011..The purpose of the current study was to identify clinical and kidney morphologic features that predict a favorable blood pressure (BP) response to renal artery stenting (RAS)...
Surgical site infections after colorectal surgery: do risk factors vary depending on the type of infection considered?Jennifer Blumetti
Department of Surgery, University of Texas, Southwestern Medical Center, Dallas, TX, USA
Surgery 142:704-11. 2007..The purpose of this study was to compare risk factors for the development of incisional versus organ/space infections in patients undergoing colorectal surgery...
Surgical complications exert a lasting effect on disease-specific health-related quality of life for patients with colorectal cancerThomas Anthony
Department of Surgery, The University of Texas Southwestern Medical School, and the Veterans Affairs North Texas Health Care System, Dallas, TX 75216, USA
Surgery 134:119-25. 2003..CONCLUSIONS: For patients who undergo treatment of colorectal cancer, HRQL at 1 year after diagnosis is still influenced significantly and negatively by the occurrence of surgical complications...
Preoperative weight loss decreases the operative time of gastric bypass at a Veterans Administration hospitalSergio Huerta
Department of Surgery, Dallas VA Medical Center, 4500 Lancaster Road, Dallas, TX 75216, USA
Obes Surg 18:508-12. 2008..This study assessed whether preoperative weight loss resulted in favorable outcomes after open Roux-en Y gastric bypass (RYGB)...
Bile salt exposure causes phosphatidyl-inositol-3-kinase-mediated proliferation in a Barrett's adenocarcinoma cell lineKshama Jaiswal
University of Texas Southwestern Medical Center at Dallas, VA North Texas Health Center, Dallas, TX 75216, USA
Surgery 136:160-8. 2004..CONCLUSIONS: Bile salts activate the PI3 kinase/Akt signaling pathway and stimulate cell growth in SEG-1. The majority of this PI3 kinase-mediated effect is secondary to increases in proliferation rather than to decreases in apoptosis...
Predictors of recurrence in veteran patients with umbilical hernia: single center experienceMassimo Asolati
Surgical Service, Dallas VA Medical Center, VA North Texas Health Care System, 4500 S Lancaster Rd, Surgical Service, MC 112, Dallas, TX 75216, USA
Am J Surg 192:627-30. 2006..Possible predictors of recurrence after elective umbilical hernia repair have not been defined clearly. The aim of this study was to determine factors that predict recurrence in patients after elective repair of umbilical hernias...
A comparison of complications associated with colostomy reversal versus ileostomy reversalChristopher Bell
Surgical Service, Dallas VA Medical Center, MC 112, 4500 Lancaster Road, Dallas, TX 75216, USA
Am J Surg 190:717-20. 2005..047). CONCLUSION: Segmental colonic excision with anastomosis and loop ileostomy may be an attractive alternative to minimize morbidity with stoma reversal...
Outcomes of laparoscopic and open colectomy at academic centersJ Esteban Varela
Minimally Invasive Surgery, Surgical Service, Veterans Affairs North Texas Health Care System, Dallas, TX, USA
Am J Surg 196:403-6. 2008..Laparoscopic techniques have emerged as a suitable approach for colon resection. This study determined and compared the outcomes of patients undergoing laparoscopic or open colectomy at United States academic centers...
Incidence and predictors of appendiceal tumors in elderly males presenting with signs and symptoms of acute appendicitisR David Todd
Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA
Am J Surg 188:500-4. 2004..Distinction between AT and appendicitis is difficult preoperatively, but AT should be suspected when patients present with longer duration of symptoms or reduced hematocrit...
Health-related quality of life and postoperative length of stay for patients with colorectal cancerShane Holloway
University of Texas Southwestern Medical, Dallas, Texas 75216, USA
J Surg Res 108:273-8. 2002..Such information may be an important and currently neglected means of risk-adjusting populations undergoing surgery for colorectal cancer for this outcome...
The metastatic lymph node ratio predicts survival in colon cancerPaul Schumacher
Department of Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, MC 9155, Dallas, TX 75390 9155, USA
Am J Surg 194:827-31; discussion 831-2. 2007..Our goal was to determine whether a lymph node ratio (LNR) would predict disease-free survival (DFS) and overall survival (OS) in a tertiary care Veterans Affairs medical center...
A strategy for reducing surgical backlogs: lessons from a veterans administration hospitalBryce W Murray
Dallas VA Medical Center, Surgical Services 112, 4500 South Lancaster Road, Dallas, TX 75216, USA
Am Surg 77:597-601. 2011..6% vs. 20.9% for weekday IHs, P = 0.75). Elective cases can be accomplished more rapidly during nontraditional operating times if there are multiple support teams and rooms available...
Assessment of comorbid conditions in veteran patients after Roux-en-Y gastric bypassSergio Huerta
University of Texas Southwestern Medical Center Veterans Administration North Texas Health Care System, 4500 Lancaster Rd, Dallas, TX 75216, United States
Am J Surg 194:48-52. 2007..The present study assessed the degree to which comorbid conditions improved after bariatric surgery in veteran patients...
Cancer risk in endoscopically unresectable colon polypsAdam C Alder
Department of Surgery, Dallas Veterans Affairs Medical Center, University of Texas Southwestern Medical Center, Dallas, TX, USA
Am J Surg 192:644-8. 2006..Neither polyp size nor histologic type appeared to be significantly associated with invasive cancer. Location of an endoscopically unresectable polyp distal to the splenic flexure confers an increased risk for occult malignancy...
Surgical therapy of peptic ulcers in the 21st century: more common than you thinkGeorge A Sarosi
Department of Surgery, North Texas Veterans Administration Medical Center, 4500 S Lancaster Rd, Dallas, TX 75216, USA
Am J Surg 190:775-9. 2005..The purpose of this study was to characterize the Veteran patients undergoing surgery for peptic ulcer disease in a modern series and to examine the effect of H. pylori status on surgical outcome and recurrence of PUD...
Deep vein harvest: predicting need for fasciotomyJ Gregory Modrall
Department of Surgery, University of Texas Southwestern Medical Center and Dallas Veterans Affairs Medical Center, Dallas, TX 75390 9157, USA
J Vasc Surg 39:387-94. 2004..The purpose of this study was to define the frequency of fasciotomy in patients undergoing deep vein harvest and to identify clinical predictors of the need for fasciotomy after deep vein harvest...
Tissue microarray constructs to predict a response to chemoradiation in rectal cancerSergio Huerta
Department of Surgery, University of Texas Southwestern Medical Center, United States
Dig Liver Dis 42:679-84. 2010..To identify, using tissue microarray (TMA), an immunohistochemical panel predictive of response to ionizing radiation (IR) in rectal cancer...
Predictors of distant metastasis and mortality in patients with stage II colorectal cancerJohn H Heinzerling
University of Texas Southwestern Medical Center Veteran s Affairs North Texas Health Care System, Dallas, Texas, USA
Am Surg 73:230-8. 2007..007; OR = 4.5) independently predicted distant metastasis, whereas preoperative carcinoembryonic antigen (P = 0.038; OR = 2.8) and patients undergoing an APR (P = 0.019; OR = 25) independently predicted mortality...
Rebleeding and survival after acute lower gastrointestinal bleedingThomas Anthony
Department of Surgery, University of Texas Southwestern Medical Center and the VA North Texas Health Care System, 4500 South Lancaster Rd, Dallas, TX 75216, USA
Am J Surg 188:485-90. 2004..Measurement of long-term outcome has been rare. The purpose of this study was to document rebleeding and survival rates in patients with acute LGIB...
Emergency surgery for colon carcinomaLane Smothers
Department of Surgery, University of Texas, Southwestern Medical Center, Dallas, Texas, USA
Dis Colon Rectum 46:24-30. 2003..The similarity between the two groups in overall survival for patients surviving the perioperative period suggests that the negative impact of emergency surgery is confined to the immediate postoperative period...
Preoperative embolization of heterotopic ossification for the treatment of a recalcitrant pressure soreEric A Appelt
Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Plast Reconstr Surg 116:50e-53e. 2005
Radiosensitization of HT-29 cells and xenografts by the nitric oxide donor DETANONOateXiaohuan Gao
Department of Surgery, Dallas VA Medical Center, University of Texas Southwestern, Dallas, Texas, USA
J Surg Oncol 100:149-58. 2009..Mechanisms of radioresistance in rectal cancer remain unclear...
Current evidence-based opinions in the management of adenocarcionoma of the rectumSergio Huerta
Division of Surgery, University of Texas Southwestern Medical Center Dallas VA Medical Center, Dallas, USA
Indian J Surg 71:356-62. 2009..In the present report, we review the current evidence in the new strategies pertaining to the multimodality approach in the management of rectal cancer...
Antiproliferative effects of Src inhibition on medullary thyroid cancerZijuan Liu
Department of Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9156, USA
J Clin Endocrinol Metab 89:3503-9. 2004..We conclude that Src-dependent MTC proliferation occurs via increased DNA synthesis and reduced apoptosis. The latter effect may be mediated by Akt survival signals. Modulation of Src activity is a potential therapeutic target in MTC...
Getting to better cancer care: results of a society of surgical oncology surveySandra L Wong
Department of Surgery, Division of Surgical Oncology, University of Michigan, 1500 E Medical Center Drive, 3310 CCC, Ann Arbor, MI, 48109 5932, USA
Ann Surg Oncol 15:2363-71. 2008..A survey of its members was conducted to determine which domains of "outcomes" are important and relevant to surgical oncologists...
Repair of ventral incisional hernia: the design of a randomized trial to compare open and laparoscopic surgical techniquesKamal M F Itani
Veterans Affairs Boston Health Care System, Boston and Harvard Universities, 1400 VFW Parkway, West Roxbury, Massachusetts 02132, USA
Am J Surg 188:22S-29S. 2004..When completed, this study will provide surgeons and their patients with information that will help guide their choice of surgical technique...
Factors associated with postoperative complications and hernia recurrence for patients undergoing inguinal hernia repair: a report from the VA Cooperative Hernia Study GroupRichard D Matthews
George E Wahlen Salt Lake City VA Health Care System and University of Utah Department of Surgery, VAMC 112, 500 Foothill Dr, Salt Lake City, UT 84148, USA
Am J Surg 194:611-7. 2007..We sought to determine perioperative variables predictive of complications or recurrence for patients undergoing surgical repair of inguinal hernias...
Green-coloured results on guaiac-based faecal occult blood testingThomas Anthony
Ann Clin Biochem 42:234; author reply 235. 2005
Practice parameters for the surveillance and follow-up of patients with colon and rectal cancerThomas Anthony
Dis Colon Rectum 47:807-17. 2004
Practice parameters for the management of rectal cancer (revised)Joe J Tjandra
Fletcher Allen Health Care, 111 Colchester Avenue, Fletcher 301, Burlington, Vermont 05401, USA
Dis Colon Rectum 48:411-23. 2005..The ultimate judgment regarding the propriety of any specific procedure must be made by the physician in light of all of the circumstances presented by the individual patient...
