Research Topics
| Samuel V AngiuoliSummaryAffiliation: University of Maryland Country: USA Publications
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Detail Information
Publications
Improving pan-genome annotation using whole genome multiple alignmentSamuel V Angiuoli
Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA
BMC Bioinformatics 12:272. 2011..Genome annotations can contain inconsistencies and errors that hinder comparative analysis even within a single species. Tools are needed to compare and improve annotation quality across sets of closely related genomes...
CloVR: a virtual machine for automated and portable sequence analysis from the desktop using cloud computingSamuel V Angiuoli
Institute for Genome Sciences IGS, University of Maryland School of Medicine, Baltimore, Maryland, USA
BMC Bioinformatics 12:356. 2011..Cloud computing platforms provide on-demand access to computing infrastructure over the Internet and can be used in combination with custom built virtual machines to distribute pre-packaged with pre-configured software...
Resources and costs for microbial sequence analysis evaluated using virtual machines and cloud computingSamuel V Angiuoli
Institute for Genome Sciences, University of Maryland Baltimore, Baltimore, Maryland, United States of America
PLoS ONE 6:e26624. 2011..Cloud computing services have been discussed as potential new bioinformatics support systems but have not been evaluated thoroughly...
Using Sybil for interactive comparative genomics of microbes on the webDavid R Riley
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
Bioinformatics 28:160-6. 2012..In addition to scalability, comparative genomics tools must also provide user-friendly interfaces such that the research scientist can explore complex data with minimal technical expertise...
Ergatis: a web interface and scalable software system for bioinformatics workflowsJoshua Orvis
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
Bioinformatics 26:1488-92. 2010..Software is also needed to simplify data management and make large-scale bioinformatics analysis accessible and reproducible to a wide class of target users...
Toward an online repository of Standard Operating Procedures (SOPs) for (meta)genomic annotationSamuel V Angiuoli
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
OMICS 12:137-41. 2008..In addition, there is no central repository to store and disseminate procedures and protocols for genome annotation. We highlight the importance of SOPs for genome annotation and endorse an online repository of SOPs...
Mugsy: fast multiple alignment of closely related whole genomesSamuel V Angiuoli
Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD, USA
Bioinformatics 27:334-42. 2011..This increasing volume of data requires tools that can quickly compare multiple whole-genome sequences, millions of base pairs in length, to aid in the study of populations, pan-genomes, and genome evolution...
A comparative genomic analysis of diverse clonal types of enterotoxigenic Escherichia coli reveals pathovar-specific conservationJason W Sahl
University of Maryland School of Medicine, Institute for Genome Sciences, Baltimore, MD, USA
Infect Immun 79:950-60. 2011..These studies increase our understanding of ETEC evolution, as well as provide insight into virulence factors and conserved proteins, which may be targets for vaccine development...
Comparative genomics of emerging human ehrlichiosis agentsJulie C Dunning Hotopp
The Institute for Genomic Research, Rockville, Maryland, USA
PLoS Genet 2:e21. 2006..These discoveries provide significant insights into the biology of these obligate intracellular pathogens...
