John A Angelos

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Randomized controlled field trial to assess efficacy of a Moraxella bovis pilin-cytotoxin-Moraxella bovoculi cytotoxin subunit vaccine to prevent naturally occurring infectious bovine keratoconjunctivitis
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, USA
    Am J Vet Res 73:1670-5. 2012
  2. ncbi Minimum inhibitory concentrations of selected antimicrobial agents for Moraxella bovoculi associated with infectious bovine keratoconjunctivitis
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    J Vet Diagn Invest 23:552-5. 2011
  3. ncbi Recombinant Moraxella bovoculi cytotoxin-ISCOM matrix adjuvanted vaccine to prevent naturally occurring infectious bovine keratoconjunctivitis
    John A Angelos
    Department of Medicine and Epidemiology, University of California, Davis, CA 95616, USA
    Vet Res Commun 34:229-39. 2010
  4. ncbi Moraxella bovoculi and infectious bovine keratoconjunctivitis: cause or coincidence?
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Vet Clin North Am Food Anim Pract 26:73-8, table of contents. 2010
  5. ncbi Differentiation of Moraxella bovoculi sp. nov. from other coccoid moraxellae by the use of polymerase chain reaction and restriction endonuclease analysis of amplified DNA
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    J Vet Diagn Invest 19:532-4. 2007
  6. ncbi Prevention of naturally occurring infectious bovine keratoconjunctivitis with a recombinant Moraxella bovis pilin-Moraxella bovis cytotoxin-ISCOM matrix adjuvanted vaccine
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Vet Microbiol 125:274-83. 2007
  7. ncbi Identification and characterization of complete RTX operons in Moraxella bovoculi and Moraxella ovis
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Vet Microbiol 125:73-9. 2007
  8. ncbi Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, 2108 Tupper Hall, Davis, CA 95616, USA
    Vet Microbiol 124:382-6. 2007
  9. ncbi Moraxella bovoculi sp. nov., isolated from calves with infectious bovine keratoconjunctivitis
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Int J Syst Evol Microbiol 57:789-95. 2007
  10. ncbi Prevention of naturally occurring infectious bovine keratoconjunctivitis with a recombinant Moraxella bovis cytotoxin-ISCOM matrix adjuvanted vaccine
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Vaccine 23:537-45. 2004

Collaborators

  • J F Hess
  • Phillip Q Spinks
  • Lisle W George
  • Klibs N Galvão
  • Erica L Dueger
  • Andrew J Borrowman
  • Merlyn J Lucas
  • Jonalee A Meyer
  • Ellen S Portis
  • Natalie S Tankersley
  • William W Ruehl
  • Kelsie M Luiz

Detail Information

Publications16

  1. ncbi Randomized controlled field trial to assess efficacy of a Moraxella bovis pilin-cytotoxin-Moraxella bovoculi cytotoxin subunit vaccine to prevent naturally occurring infectious bovine keratoconjunctivitis
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California Davis, Davis, CA 95616, USA
    Am J Vet Res 73:1670-5. 2012
    ..To evaluate efficacy of a recombinant Moraxella bovis pilin-cytotoxin-Moraxella bovoculi cytotoxin subunit vaccine to prevent naturally occurring infectious bovine keratoconjunctivitis (IBK)...
  2. ncbi Minimum inhibitory concentrations of selected antimicrobial agents for Moraxella bovoculi associated with infectious bovine keratoconjunctivitis
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    J Vet Diagn Invest 23:552-5. 2011
    ..The low MIC(90) of these M. bovoculi isolates suggests that commonly used antibiotics for treatment of IBK associated with M. bovis should also be effective against M. bovoculi...
  3. ncbi Recombinant Moraxella bovoculi cytotoxin-ISCOM matrix adjuvanted vaccine to prevent naturally occurring infectious bovine keratoconjunctivitis
    John A Angelos
    Department of Medicine and Epidemiology, University of California, Davis, CA 95616, USA
    Vet Res Commun 34:229-39. 2010
    ..bovis and M. bovoculi exist. Use of M. bovoculi antigens alone in vaccines to prevent IBK may not be beneficial in herds where IBK is associated with both M. bovoculi and M. bovis...
  4. ncbi Moraxella bovoculi and infectious bovine keratoconjunctivitis: cause or coincidence?
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Vet Clin North Am Food Anim Pract 26:73-8, table of contents. 2010
    ..Developers of vaccines against IBK should consider including M bovoculi antigens in vaccines to prevent IBK...
  5. ncbi Differentiation of Moraxella bovoculi sp. nov. from other coccoid moraxellae by the use of polymerase chain reaction and restriction endonuclease analysis of amplified DNA
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    J Vet Diagn Invest 19:532-4. 2007
    ..bovoculi sp. nov. and all possessed an AfaI site. A PCR coupled with restriction analysis of amplified DNA can aid in identifying M. bovoculi sp. nov...
  6. ncbi Prevention of naturally occurring infectious bovine keratoconjunctivitis with a recombinant Moraxella bovis pilin-Moraxella bovis cytotoxin-ISCOM matrix adjuvanted vaccine
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Vet Microbiol 125:274-83. 2007
    ..Efficacy of an M. bovis vaccine may be reduced in herds where IBK is associated with M. bovoculi sp. nov...
  7. ncbi Identification and characterization of complete RTX operons in Moraxella bovoculi and Moraxella ovis
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Vet Microbiol 125:73-9. 2007
    ..bovoculi and M. ovis; this antiserum did not neutralize the hemolytic activity of M. bovis. M. bovoculi and M. ovis possess genes that encode proteins related to pathogenic factors of M. bovis...
  8. ncbi Relatedness of cytotoxins from geographically diverse isolates of Moraxella bovis
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, 2108 Tupper Hall, Davis, CA 95616, USA
    Vet Microbiol 124:382-6. 2007
    ..Vaccines against IBK that incorporate MbxA as antigen may offer protection against geographically diverse strains of M. bovis...
  9. ncbi Moraxella bovoculi sp. nov., isolated from calves with infectious bovine keratoconjunctivitis
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Int J Syst Evol Microbiol 57:789-95. 2007
    ..nov. is proposed. The type strain is strain 237(T) (=ATCC BAA-1259(T)=CCUG 52049(T))...
  10. ncbi Prevention of naturally occurring infectious bovine keratoconjunctivitis with a recombinant Moraxella bovis cytotoxin-ISCOM matrix adjuvanted vaccine
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Vaccine 23:537-45. 2004
    ..The trend for a reduced cumulative proportion of IBK in the vaccinated calves over the 20 week trial suggests that a recombinant M. bovis cytotoxin vaccine may be beneficial in helping to prevent naturally occurring IBK...
  11. ncbi An RTX operon in hemolytic Moraxella bovis is absent from nonhemolytic strains
    John A Angelos
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, 2108 Tupper Hall, Davis 95616, USA
    Vet Microbiol 92:363-77. 2003
    ..These strains did, however, amplify with primers specific for the 5' region flanking mbxC. M. bovis harbors a classical RTX operon that is absent in nonhemolytic strains...
  12. ncbi Effectiveness of a cytolysin-enriched vaccine for protection of cattle against infectious bovine keratoconjunctivitis
    Lisle W George
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Am J Vet Res 66:136-42. 2005
    ..CONCLUSIONS AND CLINICAL RELEVANCE: Calves that were vaccinated with a cytolysin-enriched vaccine had some resistance to IBK. Vaccines containing concentrated diafiltered M bovis cytolysin could protect beef calves against IBK...
  13. ncbi Efficacy of a long-acting formulation of ceftiofur crystalline-free acid for the treatment of naturally occurring infectious bovine keratoconjunctivitis
    Erica L Dueger
    Department of Veterinary Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Am J Vet Res 65:1185-8. 2004
    ..CONCLUSIONS AND CLINICAL RELEVANCE: A single dose of CCFA administered into the posterior aspect of a pinna had a positive treatment effect against naturally occurring IBK in calves with corneal ulcerations...
  14. ncbi Ulcerative blepharitis and conjunctivitis in adult dairy cows and association with Moraxella bovoculi
    Klibs N Galvão
    Veterinary Medicine Teaching and Research Center, University of California Davis, Tulare, California 93274, USA
    Can Vet J 51:400-2. 2010
    ..Lesions typically affected 1 eye, and involved the eyelid skin and conjunctiva. Oxytetracycline treatment led to cure within 2 wk...
  15. ncbi Stability, antigenicity, and aggregation of Moraxella bovis cytolysin after purification and storage
    Lisle W George
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Am J Vet Res 65:977-83. 2004
    ..bovis isolates. Diafiltration could be useful for bulk semipurification of M. bovis cytolysin. Cytolysin-enriched vaccines of M. bovis could be contaminated by endotoxin...
  16. ncbi The Moraxella bovis RTX toxin locus mbx defines a pathogenicity island
    John F Hess
    Department of Cell Biology and Human Anatomy, School of Medicine, University of California, 3301 Tupper Hall, Davis, CA 95616, USA
    J Med Microbiol 55:443-9. 2006
    ..bovis, suggests that this RTX operon is located on a mobile genetic element, and supports the designation of this region as a pathogenicity island, which is believed to be the first such element demonstrated in M. bovis...