Matthew E Andrzejewski
Affiliation: University of Wisconsin
- A comparison of adult and adolescent rat behavior in operant learning, extinction, and behavioral inhibition paradigmsMatthew E Andrzejewski
University of Wisconsin Madison, Waisman Center, 1500 Highland Avenue, Madison, WI 53719, USA
Behav Neurosci 125:93-105. 2011....
- Is extinction the hallmark of operant discrimination? Reinforcement and S(Delta) effectsMatthew E Andrzejewski
University of Wisconsin Madison, Madison, WI 53719, USA
Behav Processes 74:49-63. 2007..In sum, it appears that higher reinforcement rates and longer S(Delta) exposure facilitate the acquisition of discriminated operant responding...
- Central amygdalar and dorsal striatal NMDA receptor involvement in instrumental learning and spontaneous behaviorMatthew E Andrzejewski
Department of Psychiatry, University of Wisconsin Madison Medical School, Madison, WI 53719, USA
Behav Neurosci 118:715-29. 2004..The present findings extend knowledge of the dynamic neurophysiological processes, instantiated in a complex neural network, required for instrumental learning in the mammalian brain...
- Pigeons' choices between fixed-interval and random-interval schedules: utility of variability?Matthew E Andrzejewski
Department of Psychiatry, University of Wisconsin Madison, 6001 Research Park Boulevard, Madison, Wisconsin 53719, USA
J Exp Anal Behav 83:129-45. 2005..The results loosely support conceptions of a "preference for variability" from foraging theory and the "utility of behavioral variability" from human decision-making literatures...
- Dissociating ventral and dorsal subicular dopamine D1 receptor involvement in instrumental learning, spontaneous motor behavior, and motivationMatthew E Andrzejewski
Department of Psychiatry, University of Wisconsin Madison, WI 53719, USA
Behav Neurosci 120:542-53. 2006..Further, D1 activation in the vSUB may be a critical component of motivational arousal associated with learned contextual cues...
- AMPA/kainate, NMDA, and dopamine D1 receptor function in the nucleus accumbens core: a context-limited role in the encoding and consolidation of instrumental memoryPepe J Hernandez
Department of Psychiatry, University of Wisconsin Madison, Madison, Wisconsin 53719, USA
Learn Mem 12:285-95. 2005..Thus, glutamate and dopamine receptors are activated in a time-limited fashion-only being required while the animals are actively engaged in the learning context...
- Operant learning requires NMDA-receptor activation in the anterior cingulate cortex and dorsomedial striatum, but not in the orbitofrontal cortexBrenda L McKee
Department of Psychiatry, University of Wisconsin, Madison, 53705, USA
Behav Neurosci 124:500-9. 2010..These data extend our understanding of the role of NMDA receptors in operant learning and behavior throughout an extended corticostriatal network...
- Intra-accumbens infusion of a muscarinic antagonist reduces food intake without altering the incentive properties of food-associated cuesMichelle L Perry
Molecular and Cellular Pharmacology and Department of Psychiatry, University of Wisconsin, Madison, WI, USA
Behav Neurosci 124:44-54. 2010..This study contributes to the growing evidence that goal-seeking behaviors are mediated by a set of neural processes distinct from those governing food reward...
- Methylphenidate preferentially increases catecholamine neurotransmission within the prefrontal cortex at low doses that enhance cognitive functionCraig W Berridge
Psychology Department, University of Wisconsin, Madison, WI 53706, USA
Biol Psychiatry 60:1111-20. 2006..Moreover, dopamine (DA) and norepinephrine (NE) are important modulators of PFC-dependent cognition. To date, the actions of low-dose psychostimulants on PFC DA and NE neurotransmission are unknown...
- Glutamate-mediated plasticity in corticostriatal networks: role in adaptive motor learningAnn E Kelley
Department of Psychiatry and Neuroscience Training Program, University of Wisconsin-Madison Medical School, 6001 Research Park Boulevard, Madison, Wisconsin 53719, USA
Ann N Y Acad Sci 1003:159-68. 2003..g., lever pressing and delivery of reward) become associated. Such basic mechanisms of plasticity within this reinforcement learning network also appear to be profoundly affected in addiction...
- Muscarinic receptor antagonism causes a functional alteration in nucleus accumbens mu-opiate-mediated feeding behaviorMichelle L Perry
Molecular and Cellular Pharmacology, University of Wisconsin Madison, 6001 Research Park Boulevard, Madison, WI 53719, USA
Behav Brain Res 197:225-9. 2009..Hence, Acb muscarinic manipulations exhibit some specificity for feeding, perhaps via interactions with the striatal opioid system...
- Adequacy of maternal iron status protects against behavioral, neuroanatomical, and growth deficits in fetal alcohol spectrum disordersEcholeah S Rufer
Molecular and Environmental Toxicology Center, University of Wisconsin Madison, Madison, Wisconsin, United States of America
PLoS ONE 7:e47499. 2012..We propose that increased attention to normalizing maternal iron status will substantially improve FASD outcome, even if maternal alcohol abuse continues. These findings offer novel insights into how alcohol damages the developing brain...
- The effect of REM sleep deprivation on motivation for food rewardErin C Hanlon
Neuroscience Training Program, University of Wisconsin-Madison, WI, USA
Behav Brain Res 163:58-69. 2005..Rather, REM sleep deprivation appears to alter systems involved in motivational processes, reward, and/or attention...
- Interactions between the CB1 receptor agonist Delta 9-THC and the CB1 receptor antagonist SR-141716 in rats: open-field revisitedTorbjörn U C Järbe
Temple University, Department of Psychology, 265 67 Weiss Hall, 1701 North 13th Street, Philadelphia, PA 19122, USA
Pharmacol Biochem Behav 73:911-9. 2002..These results may show that SR-141716 is acting as (i) an inverse agonist and/or (ii) that the endogenous cannabinoid system is tonically active under certain conditions...
- NMDA and D1 receptor involvement in operant learningMatthew Andrzejewski; Fiscal Year: 2005..The proposed research integrates cannula mapping techniques, pharmacological manipulations and advanced behavioral analysis. ..