N C Andreasen

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi request reprint The cerebellum plays a role in conscious episodic memory retrieval
    N C Andreasen
    Mental Health Clinical Research Center, University of Iowa College of Medicine, Iowa City 52242 1057, USA
    Hum Brain Mapp 8:226-34. 1999
  2. ncbi request reprint The effect of antipsychotic medication on relative cerebral blood perfusion in schizophrenia: assessment with technetium-99m hexamethyl-propyleneamine oxime single photon emission computed tomography
    D D Miller
    Department of Psychiatry, University of Iowa Hospital and Clinics, University of Iowa College of Medicine, Iowa City 52242 1057, USA
    Biol Psychiatry 41:550-9. 1997
  3. ncbi request reprint Untreated initial psychosis: its relation to quality of life and symptom remission in first-episode schizophrenia
    B C Ho
    Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Am J Psychiatry 157:808-15. 2000
  4. ncbi request reprint Prevalence of depressive symptoms early in the course of schizophrenia
    T H Wassink
    Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa Hospitals and Clinics, University of Iowa College of Medicine, Iowa City 52242, USA
    Am J Psychiatry 156:315-6. 1999
  5. ncbi request reprint Abnormal brain morphology in patients with isolated cleft lip, cleft palate, or both: a preliminary analysis
    P Nopoulos
    Mental Health Clinical Research Center, University of Iowa Hospitals and Clinics, Iowa City 52242, USA
    Cleft Palate Craniofac J 37:441-6. 2000
  6. ncbi request reprint Quantitative in vivo measurement of gyrification in the human brain: changes associated with aging
    V A Magnotta
    Mental Health Clinical Research Center, The University of Iowa College of Medicine and Hospitals and Clinics, Iowa City 52242, USA
    Cereb Cortex 9:151-60. 1999
  7. ncbi request reprint Change in basal ganglia volume over 2 years in patients with schizophrenia: typical versus atypical neuroleptics
    P W Corson
    Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52242, USA
    Am J Psychiatry 156:1200-4. 1999
  8. ncbi request reprint Enlarged cavum septi pellucidi in patients with schizophrenia: clinical and cognitive correlates
    P Nopoulos
    Mental Health Clinic Research Centre, University of Iowa College of Medicine, Iowa City 52242, USA
    J Neuropsychiatry Clin Neurosci 12:344-9. 2000
  9. ncbi request reprint Insular cortex abnormalities in schizophrenia: a structural magnetic resonance imaging study of first-episode patients
    B Crespo-Facorro
    Mental Health Clinical Research Center, Department of Psychiatry, College of Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242 1057, USA
    Schizophr Res 46:35-43. 2000
  10. ncbi request reprint Neural mechanisms of anhedonia in schizophrenia: a PET study of response to unpleasant and pleasant odors
    B Crespo-Facorro
    University of Iowa Hospitals and Clinics, Mental Health Clinical Research Center, Room 2911 JPP, 200 Hawkins Dr, Iowa City, IA 52242-1057, USA
    JAMA 286:427-35. 2001

Collaborators

Detail Information

Publications32

  1. ncbi request reprint The cerebellum plays a role in conscious episodic memory retrieval
    N C Andreasen
    Mental Health Clinical Research Center, University of Iowa College of Medicine, Iowa City 52242 1057, USA
    Hum Brain Mapp 8:226-34. 1999
    ..These activations confirm a cognitive role for the cerebellum, which may participate in an interactive cortical-cerebellar network that initiates and monitors the conscious retrieval of episodic memory...
  2. ncbi request reprint The effect of antipsychotic medication on relative cerebral blood perfusion in schizophrenia: assessment with technetium-99m hexamethyl-propyleneamine oxime single photon emission computed tomography
    D D Miller
    Department of Psychiatry, University of Iowa Hospital and Clinics, University of Iowa College of Medicine, Iowa City 52242 1057, USA
    Biol Psychiatry 41:550-9. 1997
    ..Functional neuroimaging techniques such as SPECT may be useful in furthering our understanding of the mechanism of antipsychotics...
  3. ncbi request reprint Untreated initial psychosis: its relation to quality of life and symptom remission in first-episode schizophrenia
    B C Ho
    Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA 52242, USA
    Am J Psychiatry 157:808-15. 2000
    ..If untreated psychosis is neurotoxic, this would form a strong basis for early intervention in schizophrenia...
  4. ncbi request reprint Prevalence of depressive symptoms early in the course of schizophrenia
    T H Wassink
    Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa Hospitals and Clinics, University of Iowa College of Medicine, Iowa City 52242, USA
    Am J Psychiatry 156:315-6. 1999
    ..The rate of depressive symptoms early in the course of schizophrenia was determined...
  5. ncbi request reprint Abnormal brain morphology in patients with isolated cleft lip, cleft palate, or both: a preliminary analysis
    P Nopoulos
    Mental Health Clinical Research Center, University of Iowa Hospitals and Clinics, Iowa City 52242, USA
    Cleft Palate Craniofac J 37:441-6. 2000
    ..The aim of this study was to determine whether adult men with cleft lip and palate (CLP) have aberrant cerebral morphology...
  6. ncbi request reprint Quantitative in vivo measurement of gyrification in the human brain: changes associated with aging
    V A Magnotta
    Mental Health Clinical Research Center, The University of Iowa College of Medicine and Hospitals and Clinics, Iowa City 52242, USA
    Cereb Cortex 9:151-60. 1999
    ..Measurements of sulcal and gyral shape may be useful in studying the mechanisms of both neurodevelopmental and neurodegenerative changes that occur during brain maturation and aging...
  7. ncbi request reprint Change in basal ganglia volume over 2 years in patients with schizophrenia: typical versus atypical neuroleptics
    P W Corson
    Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52242, USA
    Am J Psychiatry 156:1200-4. 1999
    ....
  8. ncbi request reprint Enlarged cavum septi pellucidi in patients with schizophrenia: clinical and cognitive correlates
    P Nopoulos
    Mental Health Clinic Research Centre, University of Iowa College of Medicine, Iowa City 52242, USA
    J Neuropsychiatry Clin Neurosci 12:344-9. 2000
    ..Thus, the greater the size of the anomaly, the greater the cognitive deficit. No relationship was found between severity of CSP and symptom measures...
  9. ncbi request reprint Insular cortex abnormalities in schizophrenia: a structural magnetic resonance imaging study of first-episode patients
    B Crespo-Facorro
    Mental Health Clinical Research Center, Department of Psychiatry, College of Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242 1057, USA
    Schizophr Res 46:35-43. 2000
    ..These abnormalities are related to the severity of psychotic symptoms. Further investigations are needed to evaluate the role of the insula in the pathophysiology of schizophrenia...
  10. ncbi request reprint Neural mechanisms of anhedonia in schizophrenia: a PET study of response to unpleasant and pleasant odors
    B Crespo-Facorro
    University of Iowa Hospitals and Clinics, Mental Health Clinical Research Center, Room 2911 JPP, 200 Hawkins Dr, Iowa City, IA 52242-1057, USA
    JAMA 286:427-35. 2001
    ..CONCLUSION: Abnormalities in the complex functional interactions between mesolimbic and frontal regions may underlie emotional disturbances in schizophrenia...
  11. ncbi request reprint Heritability of BDNF alleles and their effect on brain morphology in schizophrenia
    T H Wassink
    Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa College of Medicine, Iowa
    Am J Med Genet 88:724-8. 1999
    ..We did not find support for BDNF as a disease gene for schizophrenia. Allelic variability of the gene may, however, influence brain morphology in these same subjects. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 88:724-728, 1999...
  12. ncbi request reprint Abnormal brain structure in adults with Van der Woude syndrome
    P Nopoulos
    Department of Psychiatry, University of Iowa College of Medicine, IA 52242, USA
    Clin Genet 71:511-7. 2007
    ....
  13. ncbi request reprint Catechol-O-methyl transferase Val158Met gene polymorphism in schizophrenia: working memory, frontal lobe MRI morphology and frontal cerebral blood flow
    B C Ho
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52252, USA
    Mol Psychiatry 10:229, 287-98. 2005
    ..Age-related changes and phenotypic heterogeneity of schizophrenia may influence the complex relationships between COMT genotype and cognition...
  14. ncbi request reprint Longitudinal study of cognitive function in first-episode and recent-onset schizophrenia
    S Gold
    Department of Psychiatry, University of Iowa, USA
    Am J Psychiatry 156:1342-8. 1999
    ..Few studies have examined the longitudinal stability of cognitive function and the relationship between cognitive performance and clinical symptoms over time in a cohort of well-treated patients with schizophrenia...
  15. ncbi request reprint Population-based association analyses of the HOPA12bp polymorphism for schizophrenia and hypothyroidism
    R A Philibert
    Department of Psychiatry, The University of Iowa, Iowa City 52242 1000, USA
    Am J Med Genet 105:130-4. 2001
    ....
  16. ncbi request reprint Functional MRI statistical software packages: a comparative analysis
    S Gold
    Department of Psychiatry, University of Iowa Hospitals and Clinics, Iowa City 52242, USA
    Hum Brain Mapp 6:73-84. 1998
    ..The functionality of each package was detailed and discussed. AFNI 2.01, SPM96, Stimulate 5.0, MEDIMAX 2.01, and FIT were tested. FIASCO, Yale, and MEDx 2.0 were described but not tested. A description of each package is provided...
  17. ncbi request reprint Tumor necrosis factor receptor-II: heritability and effect on brain morphology in schizophrenia
    T H Wassink
    Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52242, USA
    Mol Psychiatry 5:678-82. 2000
    ..We found no support, therefore, for TNF-RII as a disease susceptibility gene for schizophrenia. The gene may, however, modify phenotypic aspects of the disease such as brain morphology and age of onset of illness...
  18. ncbi request reprint Correlating and predicting psychiatric symptom ratings: Spearman's r versus Kendall's tau correlation
    S Arndt
    Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa, Iowa City 52242, USA
    J Psychiatr Res 33:97-104. 1999
    ....
  19. ncbi request reprint Increased incidence of a midline brain anomaly in patients with nonsyndromic clefts of the lip and/or palate
    P Nopoulos
    Department of Psychiatry, University of Iowa College of Medicine, 500 Newton Road, Iowa City, IA 52242, USA
    J Neuroimaging 11:418-24. 2001
    ....
  20. ncbi request reprint Color enhancement of multispectral MR images: improving the visualization of subcortical structures
    J Ward
    Mental Health Clinical Research Center, University of Iowa Hospitals and Clinics, Iowa City, IA, USA
    J Comput Assist Tomogr 25:942-9. 2001
    ..quot; They were developed to improve the delineation of small brain structures composed of mixed tissue types, such as the basal ganglia...
  21. ncbi request reprint Developmental brain anomalies in children with attention-deficit hyperactivity disorder
    P Nopoulos
    Mental Health Clinical Research Center, University of Iowa Hospitals and Clinics, Iowa City 52242, USA
    J Child Neurol 15:102-8. 2000
    ..These findings support and extend the idea that ADHD is of developmental origin, and further suggest that the timing of aberrant brain development could be in early gestation...
  22. ncbi request reprint Schizophrenia
    S K Schultz
    Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa, Iowa City 52242, USA
    Lancet 353:1425-30. 1999
    ..Despite these advances, treatment of symptoms and psychosocial and cognitive impairments remains only partially successful for many patients...
  23. ncbi request reprint Sex differences in the absence of massa intermedia in patients with schizophrenia versus healthy controls
    P C Nopoulos
    Mental Health Clinical Research Center, University of Iowa College of Medicine, 52242, Iowa City, IA, USA
    Schizophr Res 48:177-85. 2001
    ..These results support the growing literature reporting structural aberration of the thalamus, as well as other midline structures in the brains of patients with schizophrenia...
  24. ncbi request reprint Clinical features characterizing young-onset and intermediate-onset schizophrenia
    S K Schultz
    University of Iowa, Department of Psychiatry, Mental Health Clinical Research Center, Iowa City, USA
    J Neuropsychiatry Clin Neurosci 12:502-5. 2000
    ..The dichotomy of early vs. late onset may extend to a younger population, reflecting a more continuous influence...
  25. ncbi request reprint Schizophrenia: the fundamental questions
    N C Andreasen
    University of Iowa Hospitals and Clinics, Mental Health Clinical Research Center, 2911 JPP, 200 Hawkins Drive, Iowa City, IA, USA
    Brain Res Brain Res Rev 31:106-12. 2000
    ..This type of unitary model may be more heuristic than early ones that were based on heterogeneous signs and symptoms...
  26. ncbi request reprint Anatomic and functional variability: the effects of filter size in group fMRI data analysis
    T White
    Mental Health Clinical Research Center, University of Iowa Hospital and Clinics, Iowa City, Iowa 52241, USA
    Neuroimage 13:577-88. 2001
    ..A discussion of the inherent difficulties in choosing an appropriate filter size is presented...
  27. ncbi request reprint [Which phenotype for the psychiatric research?]
    N C Andreasen
    Mental Health Clinical Research Center, University of Iowa College of Medicine and Hospitals and Clinics, 200 Hawkins Dr, Iowa City, IA 52242, USA
    Encephale 28:S16-20. 2002
  28. ncbi request reprint Effects of olanzapine on cerebellar functional connectivity in schizophrenia measured by fMRI during a simple motor task
    K E Stephan
    Computational Systems Neuroscience Group, C. and O. Vogt Brain Research Institute, Heinrich-Heine-University, , Germany
    Psychol Med 31:1065-78. 2001
    ..Altogether, our findings suggest that olanzapine has a stronger differential effect on neural activity in prefrontal cortex and thalamus than in motor structures...
  29. ncbi request reprint [Cognition and emotion in schizophrenia: neuroimaging approach]
    N C Andreasen
    Department of Psychiatry, University of Iowa Hospitals and Clinics, Room 2712A JPP, 200 Hawkins Drive, Iowa City, IA 52242 1057, USA
    Encephale 28:S14-5. 2002
  30. ncbi request reprint Neural basis of novel and well-learned recognition memory in schizophrenia: a positron emission tomography study
    B Crespo-Facorro
    Mental Health-Clinical Research Center, Department of Psychiatry, College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    Hum Brain Mapp 12:219-31. 2001
    ..During recognition of novel material, patients failed to activate frontal/limbic regions, recruiting a set of posterior perceptual brain regions instead...
  31. ncbi request reprint Structure and function of the superior temporal plane in adult males with cleft lip and palate: pathologic enlargement with no relationship to childhood hearing deficits
    A S Shriver
    Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    J Child Psychol Psychiatry 47:994-1002. 2006
    ..The hypothesis for the current study was that the STP in subjects with NSCLP would be structurally abnormal and that the abnormality would be related to cognitive deficit, but not to developmental hearing deficit...
  32. ncbi request reprint Comparison of the effects of risperidone and haloperidol on regional cerebral blood flow in schizophrenia
    D D Miller
    The Mental Health Clinical Research Center--Major Psychoses, Department of Psychiatry, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Biol Psychiatry 49:704-15. 2001
    ..These findings emphasize the importance of controlling for both medication status and the individual antipsychotic in neuroimaging studies...