Daniel H Anderson

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint An interfacial mechanism and a class of inhibitors inferred from two crystal structures of the Mycobacterium tuberculosis 30 kDa major secretory protein (Antigen 85B), a mycolyl transferase
    D H Anderson
    UCLA DOE Laboratory of Structural Biology and Molecular Medicine, University of California, Los Angeles, CA 90095 1570, USA
    J Mol Biol 307:671-81. 2001
  2. ncbi request reprint Granulysin crystal structure and a structure-derived lytic mechanism
    Daniel H Anderson
    Howard Hughes Medical Institute, 5 748 MacDonald, Box 951662, Los Angeles, CA 90095 1662, USA
    J Mol Biol 325:355-65. 2003
  3. ncbi request reprint Granulysin-derived peptides demonstrate antimicrobial and anti-inflammatory effects against Propionibacterium acnes
    Jamie E McInturff
    Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA
    J Invest Dermatol 125:256-63. 2005
  4. ncbi request reprint The TB structural genomics consortium: providing a structural foundation for drug discovery
    Celia W Goulding
    Bioscience Division, Mail Stop M888, Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    Curr Drug Targets Infect Disord 2:121-41. 2002

Collaborators

Detail Information

Publications4

  1. ncbi request reprint An interfacial mechanism and a class of inhibitors inferred from two crystal structures of the Mycobacterium tuberculosis 30 kDa major secretory protein (Antigen 85B), a mycolyl transferase
    D H Anderson
    UCLA DOE Laboratory of Structural Biology and Molecular Medicine, University of California, Los Angeles, CA 90095 1570, USA
    J Mol Biol 307:671-81. 2001
    ..Based on the trehalose-bound structure, we suggest a new class of antituberculous drugs, made by connecting two trehalose molecules by an amphipathic linker...
  2. ncbi request reprint Granulysin crystal structure and a structure-derived lytic mechanism
    Daniel H Anderson
    Howard Hughes Medical Institute, 5 748 MacDonald, Box 951662, Los Angeles, CA 90095 1662, USA
    J Mol Biol 325:355-65. 2003
    ..The loosely packed core facilitates a hinge or scissors motion towards exposure of hydrophobic surface that we propose tunnels the granulysin into the fracturing target membrane...
  3. ncbi request reprint Granulysin-derived peptides demonstrate antimicrobial and anti-inflammatory effects against Propionibacterium acnes
    Jamie E McInturff
    Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA
    J Invest Dermatol 125:256-63. 2005
    ..acnes-stimulated cytokine release. Taken together, these data suggest that granulysin peptides may be useful as topical therapeutic agents, providing alternatives to current acne therapies...
  4. ncbi request reprint The TB structural genomics consortium: providing a structural foundation for drug discovery
    Celia W Goulding
    Bioscience Division, Mail Stop M888, Los Alamos National Laboratory, Los Alamos, NM 87545, USA
    Curr Drug Targets Infect Disord 2:121-41. 2002
    ..The Consortium has determined structures of 28 proteins from TB to date. These protein structures are already providing a basis for drug discovery efforts...