Research Topics
| K Js AnandSummaryAffiliation: University of Arkansas for Medical Sciences Country: USA Publications
Research Grants
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Detail Information
Publications
Pain assessment in preterm neonatesK J S Anand
Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
Pediatrics 119:605-7. 2007
Pharmacological approaches to the management of pain in the neonatal intensive care unitK J S Anand
Department of Pediatrics, University of Arkansas for Medical Sciences, AR 72202, USA
J Perinatol 27:S4-S11. 2007..Clinicians must understand the contextual circumstances underlying pain in individual neonates and tailor therapy accordingly, using the most current evidence related to neonatal pain assessment and management...
Tolerance and withdrawal from prolonged opioid use in critically ill childrenKanwaljeet J S Anand
Department of Pediatrics, Le Bonheur Children s Hospital and University of Tennessee Health Science Center, Memphis, Tennessee, USA
Pediatrics 125:e1208-25. 2010..After prolonged opioid exposure, children develop opioid-induced hyperalgesia, tolerance, and withdrawal. Strategies for prevention and management should be based on the mechanisms of opioid tolerance and withdrawal...
Ketamine reduces the cell death following inflammatory pain in newborn rat brainKanwaljeet J S Anand
Pain Neurobiology Lab, Arkansas Children s Hospital Research Institute, Little Rock, Arkansas 72202, USA
Pediatr Res 62:283-90. 2007..Ketamine analgesia mitigates most of these effects...
Analgesia and local anesthesia during invasive procedures in the neonateK J S Anand
Department of Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, USA
Clin Ther 27:844-76. 2005....
Love, pain, and intensive careK J S Anand
Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
Pediatrics 121:825-7. 2008
Summary proceedings from the neonatal pain-control groupKanwaljeet J S Anand
Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
Pediatrics 117:S9-S22. 2006..Full-length articles on procedural pain, sedation and analgesia for ventilated infants, perioperative pain, and study designs for neonatal pain research were published in Clinical Therapeutics (June 2005)...
Effects of morphine analgesia in ventilated preterm neonates: primary outcomes from the NEOPAIN randomised trialK J S Anand
Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA
Lancet 363:1673-82. 2004....
Analgesia for skin-breaking procedures in newborns and children: what works best?K J S Anand
Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, College of Medicine, Little Rock, Arkansas, USA
CMAJ 179:11-2. 2008
Ketamine analgesia for inflammatory pain in neonatal rats: a factorial randomized trial examining long-term effectsCynthia R Rovnaghi
Departments of Pediatrics, Anesthesiology, Pharmacology, Neurobiology and Developmental Sciences, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
Behav Brain Funct 4:35. 2008..abstract:..
Morphine pharmacokinetics and pharmacodynamics in preterm and term neonates: secondary results from the NEOPAIN trialK J S Anand
Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
Br J Anaesth 101:680-9. 2008..Relationships between plasma morphine concentrations and neonatal responses to endotracheal tube (ETT) suctioning are unknown in preterm neonates...
Analgesia and anesthesia for neonates: study design and ethical issuesK J S Anand
Department of Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, USA
Clin Ther 27:814-43. 2005....
Neurodevelopmental changes of fetal painCurtis L Lowery
Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Semin Perinatol 31:275-82. 2007..Scientific data, not religious or political conviction, should guide the desperately needed research in this field. In the meantime, it seems prudent to avoid pain during gestation...
Long-term deficits of preterm birth: evidence for arousal and attentional disturbancesR Whit Hall
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Clin Neurophysiol 119:1281-91. 2008..Quantitative measures of pre-attentional, attentional and frontal lobe processes were compared to evaluate quantitative measures of these deficits in Ex-Preterm vs. Ex-Term adolescents...
Redefining the golden hour in pediatric transportMichael H Stroud
University of Arkansas for Medical Sciences, Department of Pediatrics, Arkansas Children s Hospital, Section of Critical Care Medicine, USA
Pediatr Crit Care Med 9:435-7. 2008..To emphasize the urgent need for research efforts and application of goal-directed therapy in the pediatric transport environment...
Reduction of bloodstream infections associated with catheters in paediatric intensive care unit: stepwise approachAdnan Bhutta
Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children s Hospital, 800 Marshall Street, Slot 512 3, Little Rock, AR 72202, USA
BMJ 334:362-5. 2007..Bloodstream infections associated with catheters were the most common nosocomial infections in one paediatric intensive care unit in 1994-7, with rates well above the national average...
Pharmacological therapy for analgesia and sedation in the newbornK J S Anand
Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
Arch Dis Child Fetal Neonatal Ed 91:F448-53. 2006....
Morphine, hypotension, and adverse outcomes among preterm neonates: who's to blame? Secondary results from the NEOPAIN trialRichard W Hall
Department of Pediatrics, University of Arkansas for Medical Sciences, Slot 512B, 4301 West Markham St, Little Rock, AR 72205, USA
Pediatrics 115:1351-9. 2005....
Hospitalizations for critically ill children with traumatic brain injuries: a longitudinal analysisJohn M Tilford
Department of Pediatrics, College of Medicine, University of Arkansas for Medical Sciences and Arkansas Children s Hospital, Little Rock, AR 72202 3591, USA
Crit Care Med 33:2074-81. 2005..This study examines the incidence, utilization of procedures, and outcomes for critically ill children hospitalized with traumatic brain injury over the period 1988-1999 to describe the benefits of improved treatment...
Gastric suction at birth associated with long-term risk for functional intestinal disorders in later lifeK J S Anand
Department of Critical Care Medicine, University of Arkansas for Medical Sciences, and Arkansas Children s Hospital, 800 Marshall Street, Little Rock, AR 72202, USA
J Pediatr 144:449-54. 2004..To test the hypothesis that noxious stimulation at birth may increase the long-term risk for developing psychosomatic or functional disorders during later life...
Assessing postoperative pain in neonates: a multicenter observational studyBonnie J Taylor
Department of Pediatrics, University of Arkansas for Medical Sciences College of Medicine and Arkansas Children's Hospital Research Institute, Little Rock, Arkansas 72202, USA
Pediatrics 118:e992-1000. 2006..Pain assessment by physicians must be emphasized, in addition to developing evidence-based guidelines for postoperative care and educating professional staff to improve postoperative pain control in neonates...
Vulnerability of the developing brain. Neuronal mechanismsAdnan T Bhutta
University of Arkansas for Medical Sciences, Arkansas Children's Hospital, 800 Marshall Street, Little Rock, AR 72202, USA
Clin Perinatol 29:357-72. 2002....
Opioid receptor desensitization contributes to thermal hyperalgesia in infant ratsJing-Gen Liu
Pain Neurobiology Laboratory, Arkansas Children's Hospital Research Institute, 1120 Marshall Street, Little Rock, AR 72202, USA
Eur J Pharmacol 491:127-36. 2004....
Effect of inborn versus outborn delivery on clinical outcomes in ventilated preterm neonates: secondary results from the NEOPAIN trialKristine G Palmer
Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
J Perinatol 25:270-5. 2005..Improvements in antenatal steroid administration to high-risk women may substantially reduce neonatal morbidity...
Cognitive and behavioral outcomes of school-aged children who were born preterm: a meta-analysisAdnan T Bhutta
Department of Pediatrics, Arkansas University for Medical Sciences, Little Rock, USA
JAMA 288:728-37. 2002..Preterm-born children also show an increased incidence of ADHD and other behaviors...
Anaesthetic neurotoxicity in rodents: is the ketamine controversy real?Adnan T Bhutta
UAMS College of Medicine Department of Pediatrics, Little Rock, Arkansas, USA
Acta Paediatr 96:1554-6. 2007
Management of abdominal compartment syndrome during extracorporeal life supportRegina Okhuysen Cawley
University of Arkansas for Medical Sciences College of Medicine, Department of Pediatrics, Little Rock, Arkansas, USA
Pediatr Crit Care Med 8:177-9. 2007..To describe the successful use of a peritoneal dialysis catheter for emergent decompression of abdominal compartment syndrome during extracorporeal life support for septic shock...
Of mice and men: should we extrapolate rodent experimental data to the care of human neonates?Sulpicio G Soriano
Anesthesiology 102:866-8; author reply 868-9. 2005
Anesthetic agents and the immature brain: are these toxic or therapeutic?Kanwaljeet J S Anand
University of Arkansas for Medical Sciences, Arkansas Chilren s Hospital, Little Rock, Arkansas, USA
Anesthesiology 101:527-30. 2004
Morphine does not provide adequate analgesia for acute procedural pain among preterm neonatesRicardo Carbajal
Neonatal Intensive Care Unit, Poissy Saint Germain Hospital, Poissy, France
Pediatrics 115:1494-500. 2005....
Morphine administration and short-term pulmonary outcomes among ventilated preterm infantsVineet Bhandari
Department of Pediatrics, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA
Pediatrics 116:352-9. 2005..The use of opioid therapy for sedation and analgesia among ventilated infants varies among care providers. The impact of opioid therapy early in the neonatal course of respiratory distress syndrome (RDS) on pulmonary outcomes is not known...
Evaluation and development of potentially better practices to improve pain management of neonatesPaul J Sharek
Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children s Hospital, Palo Alto, CA 94304, USA
Pediatrics 118:S78-86. 2006..The objective for this study was to use proven quality improvement methods to develop a process to improve neonatal pain management collaboratively...
Anesthetic neurotoxicity in newborns: should we change clinical practice?Kanwaljeet J S Anand
Anesthesiology 107:2-4. 2007
Research Grants
- PCCM Network: Remedies for Opioid Tolerance & WithdrawalKANWALJEET ANAND; Fiscal Year: 2007....
