K Js Anand

Summary

Affiliation: University of Arkansas for Medical Sciences
Country: USA

Publications

  1. ncbi Pain assessment in preterm neonates
    K J S Anand
    Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Pediatrics 119:605-7. 2007
  2. ncbi Pharmacological approaches to the management of pain in the neonatal intensive care unit
    K J S Anand
    Department of Pediatrics, University of Arkansas for Medical Sciences, AR 72202, USA
    J Perinatol 27:S4-S11. 2007
  3. pmc Tolerance and withdrawal from prolonged opioid use in critically ill children
    Kanwaljeet J S Anand
    Department of Pediatrics, Le Bonheur Children s Hospital and University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Pediatrics 125:e1208-25. 2010
  4. ncbi Ketamine reduces the cell death following inflammatory pain in newborn rat brain
    Kanwaljeet J S Anand
    Pain Neurobiology Lab, Arkansas Children s Hospital Research Institute, Little Rock, Arkansas 72202, USA
    Pediatr Res 62:283-90. 2007
  5. ncbi Analgesia and local anesthesia during invasive procedures in the neonate
    K J S Anand
    Department of Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, USA
    Clin Ther 27:844-76. 2005
  6. doi Love, pain, and intensive care
    K J S Anand
    Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Pediatrics 121:825-7. 2008
  7. ncbi Summary proceedings from the neonatal pain-control group
    Kanwaljeet J S Anand
    Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Pediatrics 117:S9-S22. 2006
  8. ncbi Effects of morphine analgesia in ventilated preterm neonates: primary outcomes from the NEOPAIN randomised trial
    K J S Anand
    Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Lancet 363:1673-82. 2004
  9. pmc Analgesia for skin-breaking procedures in newborns and children: what works best?
    K J S Anand
    Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, College of Medicine, Little Rock, Arkansas, USA
    CMAJ 179:11-2. 2008
  10. pmc Ketamine analgesia for inflammatory pain in neonatal rats: a factorial randomized trial examining long-term effects
    Cynthia R Rovnaghi
    Departments of Pediatrics, Anesthesiology, Pharmacology, Neurobiology and Developmental Sciences, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Behav Brain Funct 4:35. 2008

Research Grants

Detail Information

Publications33

  1. ncbi Pain assessment in preterm neonates
    K J S Anand
    Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Pediatrics 119:605-7. 2007
  2. ncbi Pharmacological approaches to the management of pain in the neonatal intensive care unit
    K J S Anand
    Department of Pediatrics, University of Arkansas for Medical Sciences, AR 72202, USA
    J Perinatol 27:S4-S11. 2007
    ..Clinicians must understand the contextual circumstances underlying pain in individual neonates and tailor therapy accordingly, using the most current evidence related to neonatal pain assessment and management...
  3. pmc Tolerance and withdrawal from prolonged opioid use in critically ill children
    Kanwaljeet J S Anand
    Department of Pediatrics, Le Bonheur Children s Hospital and University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Pediatrics 125:e1208-25. 2010
    ..After prolonged opioid exposure, children develop opioid-induced hyperalgesia, tolerance, and withdrawal. Strategies for prevention and management should be based on the mechanisms of opioid tolerance and withdrawal...
  4. ncbi Ketamine reduces the cell death following inflammatory pain in newborn rat brain
    Kanwaljeet J S Anand
    Pain Neurobiology Lab, Arkansas Children s Hospital Research Institute, Little Rock, Arkansas 72202, USA
    Pediatr Res 62:283-90. 2007
    ..Ketamine analgesia mitigates most of these effects...
  5. ncbi Analgesia and local anesthesia during invasive procedures in the neonate
    K J S Anand
    Department of Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, USA
    Clin Ther 27:844-76. 2005
    ....
  6. doi Love, pain, and intensive care
    K J S Anand
    Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Pediatrics 121:825-7. 2008
  7. ncbi Summary proceedings from the neonatal pain-control group
    Kanwaljeet J S Anand
    Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Pediatrics 117:S9-S22. 2006
    ..Full-length articles on procedural pain, sedation and analgesia for ventilated infants, perioperative pain, and study designs for neonatal pain research were published in Clinical Therapeutics (June 2005)...
  8. ncbi Effects of morphine analgesia in ventilated preterm neonates: primary outcomes from the NEOPAIN randomised trial
    K J S Anand
    Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Lancet 363:1673-82. 2004
    ....
  9. pmc Analgesia for skin-breaking procedures in newborns and children: what works best?
    K J S Anand
    Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, College of Medicine, Little Rock, Arkansas, USA
    CMAJ 179:11-2. 2008
  10. pmc Ketamine analgesia for inflammatory pain in neonatal rats: a factorial randomized trial examining long-term effects
    Cynthia R Rovnaghi
    Departments of Pediatrics, Anesthesiology, Pharmacology, Neurobiology and Developmental Sciences, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Behav Brain Funct 4:35. 2008
    ..abstract:..
  11. pmc Morphine pharmacokinetics and pharmacodynamics in preterm and term neonates: secondary results from the NEOPAIN trial
    K J S Anand
    Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
    Br J Anaesth 101:680-9. 2008
    ..Relationships between plasma morphine concentrations and neonatal responses to endotracheal tube (ETT) suctioning are unknown in preterm neonates...
  12. ncbi Analgesia and anesthesia for neonates: study design and ethical issues
    K J S Anand
    Department of Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, USA
    Clin Ther 27:814-43. 2005
    ....
  13. ncbi Neurodevelopmental changes of fetal pain
    Curtis L Lowery
    Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Semin Perinatol 31:275-82. 2007
    ..Scientific data, not religious or political conviction, should guide the desperately needed research in this field. In the meantime, it seems prudent to avoid pain during gestation...
  14. pmc Long-term deficits of preterm birth: evidence for arousal and attentional disturbances
    R Whit Hall
    Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Clin Neurophysiol 119:1281-91. 2008
    ..Quantitative measures of pre-attentional, attentional and frontal lobe processes were compared to evaluate quantitative measures of these deficits in Ex-Preterm vs. Ex-Term adolescents...
  15. doi Redefining the golden hour in pediatric transport
    Michael H Stroud
    University of Arkansas for Medical Sciences, Department of Pediatrics, Arkansas Children s Hospital, Section of Critical Care Medicine, USA
    Pediatr Crit Care Med 9:435-7. 2008
    ..To emphasize the urgent need for research efforts and application of goal-directed therapy in the pediatric transport environment...
  16. pmc Reduction of bloodstream infections associated with catheters in paediatric intensive care unit: stepwise approach
    Adnan Bhutta
    Department of Pediatrics, University of Arkansas for Medical Sciences, Arkansas Children s Hospital, 800 Marshall Street, Slot 512 3, Little Rock, AR 72202, USA
    BMJ 334:362-5. 2007
    ..Bloodstream infections associated with catheters were the most common nosocomial infections in one paediatric intensive care unit in 1994-7, with rates well above the national average...
  17. pmc Pharmacological therapy for analgesia and sedation in the newborn
    K J S Anand
    Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Arch Dis Child Fetal Neonatal Ed 91:F448-53. 2006
    ....
  18. ncbi Morphine, hypotension, and adverse outcomes among preterm neonates: who's to blame? Secondary results from the NEOPAIN trial
    Richard W Hall
    Department of Pediatrics, University of Arkansas for Medical Sciences, Slot 512B, 4301 West Markham St, Little Rock, AR 72205, USA
    Pediatrics 115:1351-9. 2005
    ....
  19. ncbi Hospitalizations for critically ill children with traumatic brain injuries: a longitudinal analysis
    John M Tilford
    Department of Pediatrics, College of Medicine, University of Arkansas for Medical Sciences and Arkansas Children s Hospital, Little Rock, AR 72202 3591, USA
    Crit Care Med 33:2074-81. 2005
    ..This study examines the incidence, utilization of procedures, and outcomes for critically ill children hospitalized with traumatic brain injury over the period 1988-1999 to describe the benefits of improved treatment...
  20. ncbi Gastric suction at birth associated with long-term risk for functional intestinal disorders in later life
    K J S Anand
    Department of Critical Care Medicine, University of Arkansas for Medical Sciences, and Arkansas Children s Hospital, 800 Marshall Street, Little Rock, AR 72202, USA
    J Pediatr 144:449-54. 2004
    ..To test the hypothesis that noxious stimulation at birth may increase the long-term risk for developing psychosomatic or functional disorders during later life...
  21. ncbi Assessing postoperative pain in neonates: a multicenter observational study
    Bonnie J Taylor
    Department of Pediatrics, University of Arkansas for Medical Sciences College of Medicine and Arkansas Children s Hospital Research Institute, Little Rock, Arkansas 72202, USA
    Pediatrics 118:e992-1000. 2006
    ..A multicenter observational study was conducted to evaluate the practices of postoperative pain assessment and management in neonates to identify specific targets for improvement in clinical practice...
  22. ncbi Vulnerability of the developing brain. Neuronal mechanisms
    Adnan T Bhutta
    University of Arkansas for Medical Sciences, Arkansas Children s Hospital, 800 Marshall Street, Little Rock, AR 72202, USA
    Clin Perinatol 29:357-72. 2002
    ....
  23. ncbi Opioid receptor desensitization contributes to thermal hyperalgesia in infant rats
    Jing Gen Liu
    Pain Neurobiology Laboratory, Arkansas Children s Hospital Research Institute, 1120 Marshall Street, Little Rock, AR 72202, USA
    Eur J Pharmacol 491:127-36. 2004
    ....
  24. ncbi Effect of inborn versus outborn delivery on clinical outcomes in ventilated preterm neonates: secondary results from the NEOPAIN trial
    Kristine G Palmer
    Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    J Perinatol 25:270-5. 2005
    ..The objective of this study was to evaluate the effect of birth center (inborn versus outborn) on morbidity and mortality for preterm neonates (23 to 32 weeks) using data collected prospectively within a uniform protocol...
  25. ncbi Cognitive and behavioral outcomes of school-aged children who were born preterm: a meta-analysis
    Adnan T Bhutta
    Department of Pediatrics, Arkansas University for Medical Sciences, Little Rock, USA
    JAMA 288:728-37. 2002
    ..The cognitive and behavioral outcomes of school-aged children who were born preterm have been reported extensively. Many of these studies have methodological flaws that preclude an accurate estimate of the long-term outcomes of prematurity...
  26. ncbi Anaesthetic neurotoxicity in rodents: is the ketamine controversy real?
    Adnan T Bhutta
    UAMS College of Medicine Department of Pediatrics, Little Rock, Arkansas, USA
    Acta Paediatr 96:1554-6. 2007
  27. ncbi Management of abdominal compartment syndrome during extracorporeal life support
    Regina Okhuysen-Cawley
    University of Arkansas for Medical Sciences College of Medicine, Department of Pediatrics, Little Rock, Arkansas, USA
    Pediatr Crit Care Med 8:177-9. 2007
    ..To describe the successful use of a peritoneal dialysis catheter for emergent decompression of abdominal compartment syndrome during extracorporeal life support for septic shock...
  28. ncbi Of mice and men: should we extrapolate rodent experimental data to the care of human neonates?
    Sulpicio G Soriano
    Anesthesiology 102:866-8; author reply 868-9. 2005
  29. ncbi Anesthetic agents and the immature brain: are these toxic or therapeutic?
    Kanwaljeet J S Anand
    University of Arkansas for Medical Sciences, Arkansas Chilren s Hospital, Little Rock, Arkansas, USA
    Anesthesiology 101:527-30. 2004
  30. ncbi Morphine does not provide adequate analgesia for acute procedural pain among preterm neonates
    Ricardo Carbajal
    Neonatal Intensive Care Unit, Poissy Saint Germain Hospital, Poissy, France
    Pediatrics 115:1494-500. 2005
    ....
  31. ncbi Morphine administration and short-term pulmonary outcomes among ventilated preterm infants
    Vineet Bhandari
    Department of Pediatrics, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA
    Pediatrics 116:352-9. 2005
    ..The use of opioid therapy for sedation and analgesia among ventilated infants varies among care providers. The impact of opioid therapy early in the neonatal course of respiratory distress syndrome (RDS) on pulmonary outcomes is not known...
  32. ncbi Evaluation and development of potentially better practices to improve pain management of neonates
    Paul J Sharek
    Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children s Hospital, Palo Alto, CA 94304, USA
    Pediatrics 118:S78-86. 2006
    ..The objective for this study was to use proven quality improvement methods to develop a process to improve neonatal pain management collaboratively...
  33. ncbi Anesthetic neurotoxicity in newborns: should we change clinical practice?
    Kanwaljeet J S Anand
    Anesthesiology 107:2-4. 2007

Research Grants3

  1. PCCM Network: Remedies for Opioid Tolerance & Withdrawal
    KANWALJEET ANAND; Fiscal Year: 2007
    ....