Research Topics
| Krow AmpofoSummaryAffiliation: University of Utah Country: USA Publications
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Detail Information
Publications
Epidemiology, complications, and cost of hospitalization in children with laboratory-confirmed influenza infectionKrow Ampofo
Division of Pediatric Infectious Disease, University of Utah Health Sciences Center, 30 North 1900 E, Room 2A100, Salt Lake City, UT 84132, USA
Pediatrics 118:2409-17. 2006..Influenza causes significant morbidity among children. Previous studies used indirect case ascertainment methods with little cost data. We sought to measure the burden of laboratory-confirmed influenza from hospitalized children...
Infectious disease issues in adoption of young childrenKrow Ampofo
Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, Utah 84108, USA
Curr Opin Pediatr 25:78-87. 2013..To provide an update and overview of infectious disease issues in children of international adoption...- The changing epidemiology of invasive pneumococcal disease at a tertiary children's hospital through the 7-valent pneumococcal conjugate vaccine era: a case for continuous surveillanceKrow Ampofo
Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, UT 84108, USA
Pediatr Infect Dis J 31:228-34. 2012..We recognized an opportunity to describe the changes in epidemiology, clinical syndromes, and serotype distribution during a 14-year period including 4 years before vaccine introduction and spanning the entire PCV7 era... - Evolution of the epidemiology of pneumococcal disease among Utah children through the vaccine eraKrow Ampofo
Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, UT 84108, USA
Pediatr Infect Dis J 30:1100-3. 2011..Despite decreases in PD among Utah children, complicated pneumonia/empyema has increased during the 7-valent pneumococcal conjugate vaccine era... 
Association of 2009 pandemic influenza A (H1N1) infection and increased hospitalization with parapneumonic empyema in children in UtahKrow Ampofo
Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, UT, USA
Pediatr Infect Dis J 29:905-9. 2010..We examined the relationship between circulating 2009 H1N1 and the occurrence of secondary bacterial parapneumonic empyema in children...- Seasonal invasive pneumococcal disease in children: role of preceding respiratory viral infectionKrow Ampofo
Division of Pediatric Infectious Disease, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
Pediatrics 122:229-37. 2008..Our objective was to demonstrate correlations between invasive pneumococcal disease in children and circulating respiratory viruses... - Molecular epidemiology of pediatric pneumococcal empyema from 2001 to 2007 in UtahCarrie L Byington
Department of Pediatrics, University of Utah, 295 Chipeta Way, Salt Lake City, UT 84108, USA
J Clin Microbiol 48:520-5. 2010..Serotype switch was not documented. Replacement disease with common ST of serotypes 1,3, 7F, and 19A rather than serotype switch was responsible for the increase in PPE in Utah children... - Epidemiology of Streptococcus pneumoniae-induced hemolytic uremic syndrome in Utah childrenJeffrey M Bender
Department of Pediatrics, Pediatric Infectious Diseases, University of Utah, Salt Lake City, Utah, USA
Pediatr Infect Dis J 29:712-6. 2010..Few studies examine the Streptococcus pneumoniae serotypes associated with HUS. Our objective was to describe the epidemiology of S. pneumoniae-related HUS (SP-HUS) and the serotypes associated with HUS in Utah children... - Evolving epidemiologic characteristics of invasive group a streptococcal disease in Utah, 2002-2010Chris Stockmann
Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, 84108, USA
Clin Infect Dis 55:479-87. 2012..Invasive group A Streptococcus (GAS) infections are associated with substantial morbidity and mortality. Recent national surveillance data report stable rates of invasive GAS disease, although these may not capture geographic variation... - Pneumococcal necrotizing pneumonia in Utah: does serotype matter?Jeffrey M Bender
Department of Pediatrics, Division of Infectious Diseases, University of Utah, USA
Clin Infect Dis 46:1346-52. 2008..Our objectives were to describe temporal trends in PNP and to evaluate pneumococcal serotypes associated with PNP in Utah... - Impact of the pneumococcal conjugate vaccine on pneumococcal parapneumonic empyemaCarrie L Byington
Department of Pediatrics, University of Utah, Salt Lake City, USA
Pediatr Infect Dis J 25:250-4. 2006..Our objective was to describe the temporal trends in PPE in Utah before and after the availability of the 7-valent pneumococcal conjugate vaccine (PCV-7)... - Population pharmacokinetic and pharmacodynamic modeling of high-dose intermittent ticarcillin-clavulanate administration in pediatric cystic fibrosis patientsJeffery T Zobell
Pharmacy, Intermountain Primary Children s Medical Center, Salt Lake City, Utah, USA
Clin Ther 33:1844-50. 2011..This dosing strategy is higher than the Food and Drug Administration (FDA)-approved package labeling. We evaluated the microbiologic efficacy of this dosing regimen... - Streptococcus pneumoniae serotypes in Utah adults at the end of the PCV7 eraBrian A Kendall
Department of Medicine, University of Utah, Salt Lake City, UT, United States
Vaccine 29:9123-6. 2011..Adult and pediatric IPD serotypes are closely associated in Utah. PCV13 vaccination in Utah children is likely to significantly impact IPD in Utah adults... - Parapneumonic empyema deaths during past century, UtahJeffrey M Bender
Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
Emerg Infect Dis 15:44-8. 2009..Vaccine strategies and antimicrobial drug stockpiling to control empyema will be important as we prepare for the next influenza pandemic... - Influenza virus infection in infants less than three months of ageJeffrey M Bender
University of Utah School of Medicine, Department of Pediatrics, Division of Pediatric Infectious Diseases, PO Box 581289, Salt Lake City, UT, USA
Pediatr Infect Dis J 29:6-9. 2010..We evaluated the presentation, outcomes, and the risk of serious bacterial infection (SBI) in infants <3 months old with influenza virus infection... - Molecular analysis improves pathogen identification and epidemiologic study of pediatric parapneumonic empyemaAnne J Blaschke
Department of Pediatrics, University of Utah, Salt, Lake City, UT, USA
Pediatr Infect Dis J 30:289-94. 2011..Epidemiologic study is complicated by the low frequency of positive cultures. We sought to describe the epidemiology of PPE in children using molecular analysis of pleural fluid... - Seasonality of acute otitis media and the role of respiratory viral activity in childrenChris Stockmann
From the Department of Pediatrics, Division of Pediatric Infectious Diseases Department of Pediatrics, Division of Hospitalist Medicine, University of Utah Health Sciences Center and Primary Children s Medical Center, Intermountain Healthcare, Salt Lake City, UT
Pediatr Infect Dis J 32:314-9. 2013..AOM and respiratory viruses both display seasonal variation. Our objective was to examine the temporal association between circulating respiratory viruses and the occurrence of pediatric ambulatory care visits for AOM... - Optimization of anti-pseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: III. fluoroquinolonesChris Stockmann
Division of Pediatric Infectious Disease, University of Utah, Salt Lake City, UT 84108, USA
Pediatr Pulmonol 48:211-20. 2013..Further study is needed to determine the tolerability and efficacy of levofloxacin in APE. At this time, the routine use of levofloxacin in the treatment of APE in pediatric and adult patients cannot be recommended... - Optimization of anti-pseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: II. cephalosporins and penicillinsJeffery T Zobell
Pharmacy, Intermountain Primary Children s Medical Center, Salt Lake City, Utah 84113, USA
Pediatr Pulmonol 48:107-22. 2013..The usefulness of high dose piperacillin (>600 mg/kg/day) may be limited due to treatment-related adverse effects. Further understanding of these adverse effects in CF patients is needed... - Optimization of anti-pseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: IV. colistimethate sodiumDavid C Young
University of Utah College of Pharmacy, Salt Lake City, Utah 84112, USA
Pediatr Pulmonol 48:1-7. 2013..thrice-daily) and its impact on resistance and clinical efficacy. Further study is needed to determine the tolerability and efficacy of extended-interval dosing of CMS in the treatment of APE... - A survey of the utilization of anti-pseudomonal beta-lactam therapy in cystic fibrosis patientsJeffery T Zobell
Department of Pharmacy, Intermountain Primary Children s Medical Center, Salt Lake City, UT 84113, USA
Pediatr Pulmonol 46:987-90. 2011..While this is of concern, it is not known if optimization of dosing strategies according to guidelines recommendations will result in clinical benefit... - Development and validation of a risk score for predicting hospitalization in children with influenza virus infectionJeffrey M Bender
Department of Pediatrics, Division of Pediatric Infectious Disease, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
Pediatr Emerg Care 25:369-75. 2009..Many children with influenza seek care in emergency settings during seasonal influenza epidemics. We hypothesized that certain features could predict the need for hospitalization in children with influenza... - Gordonia species: emerging pathogens in pediatric patients that are identified by 16S ribosomal RNA gene sequencingAnne J Blaschke
Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Utah, Salt Lake City, UT, USA
Clin Infect Dis 45:483-6. 2007.... - Optimization of anti-pseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: I. aztreonam and carbapenemsJeffery T Zobell
Pharmacy, Intermountain Primary Children s Medical Center, Salt Lake City, UT, USA
Pediatr Pulmonol 47:1147-58. 2012..The usefulness of imipenem-cilastatin may be limited due to the rapid development of resistance... - Tularemia with vesicular skin lesions may be mistaken for infection with herpes virusesCarrie L Byington
Department of Pediatrics, University of Utah, Salt Lake City, UT 84132, USA
Clin Infect Dis 47:e4-6. 2008..Clinicians must recognize the cutaneous manifestations of tularemia and be able to distinguish these from lesions seen with herpes viruses... - Rapid increase in use of antiviral therapy for hospitalized children with influenza during the 2009 H1N1 epidemicAdam L Hersh
Division of Pediatric Infectious Diseases, University of Utah, Salt Lake City, UT, USA
Pediatr Infect Dis J 30:895-7. 2011..This increased sharply to 84% during the 2009 H1N1 period, indicating a favorable response by physicians to clinical guidelines... - Management of parapneumonic empyemaKrow Ampofo
Division of Pediatric Infectious Disease, University of Utah School of Medicine, Salt Lake City, Utah, USA
Pediatr Infect Dis J 26:445-6. 2007 - High dose intermittent ticarcillin-clavulanate administration in pediatric cystic fibrosis patientsJeffery T Zobell
Pharmacy, Intermountain Primary Children s Medical Center, 100 North Mario Capecchi Drive, Salt Lake City, UT 84113, USA
J Cyst Fibros 9:280-3. 2010..This dosing strategy is higher than the Cystic Fibrosis Foundation (CFF) recommendations and the Food and Drug Administration (FDA) approved package labeling. The purpose is to determine the safety of this dosing regimen... - Coccidioides immitis meningitis in a patient with hyperimmunoglobulin E syndrome due to a novel mutation in signal transducer and activator of transcriptionAnnie E Powers
Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
Pediatr Infect Dis J 28:664-6. 2009..We report the first case of Coccidioides immitis meningitis in a patient with HIES. Coccidioides should be included in the differential diagnosis for central nervous system infections in HIES patients... - Bartonella vinsonii endocarditis in an adolescent with congenital heart diseaseLiset Olarte
Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah, Salt Lake City, UT 84108, USA
Pediatr Infect Dis J 31:531-4. 2012..berkhoffii endocarditis in a 19-year-old male with congenital heart disease. Diagnosis was established by Bartonella antibodies detected by immunofluorescence, and polymerase chain reaction amplification and sequencing from blood... - Mollicute infections in neonatesRosemary C She
Department of Pathology, University of Utah, Salt Lake City, UT, USA
Pediatr Infect Dis J 28:248-50. 2009..When mollicute infection is suspected, clinicians should alert laboratories, which will optimize methods of detection... - Family clusters of variant X-linked chronic granulomatous diseaseJeffrey M Bender
Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, USA
Pediatr Infect Dis J 28:529-33. 2009..A high index of suspicion in the setting of unusual infections such as Burkholderia cepacia pneumonia is essential to make the diagnosis. Family screening can lead to early intervention, prophylaxis, and appropriate genetic counseling... - Oseltamivir pharmacokinetics, dosing, and resistance among children aged <2 years with influenzaDavid W Kimberlin
Department of Pediatrics
J Infect Dis 207:709-20. 2013..Conclusions. The appropriate twice-daily oral oseltamivir dose for infants ≤8 months of age is 3.0 mg/kg, while the dose for infants 9-11 months old is 3.5 mg/kg. Clinical Trials Registration. NCT00391768... - Congenital cytomegalovirus infection: progressive postnatal chorioretinitisJacob W Brubaker
University of Utah, Salt Lake City, Utah, USA
J Pediatr Ophthalmol Strabismus 46:249-51. 2009..Optimal treatment of this disease is not well established. The authors describe an infant who had congenital cytomegalovirus infection with postnatal progression of chorioretinitis and required an extended course of ganciclovir therapy... - Heightened neurologic complications in children with pandemic H1N1 influenzaJeffrey J Ekstrand
Division of Pediatric Neurology, University of Utah School of Medicine, Salt Lake City, UT 84108, USA
Ann Neurol 68:762-6. 2010..In addition, we noted a trend toward heightened neurological complications following second wave influenza activity... - Linezolid treatment of vancomycin-resistant Enterococcus faecium ventriculitisPhilip L Graham
Departments of Pediatrics and Epidemiology, Columbia, University, New York, NY 10032, USA
Pediatr Infect Dis J 21:798-800. 2002..The patient tolerated the therapy without adverse effects...