Neil M Ampel

Summary

Affiliation: University of Arizona
Country: USA

Publications

  1. ncbi request reprint The complex immunology of human coccidioidomycosis
    Neil M Ampel
    Medical Service, 1 111, SAVAHCS, 3601 S Sixth Avenue, Tucson, AZ 85723, USA
    Ann N Y Acad Sci 1111:245-58. 2007
  2. ncbi request reprint Coccidioidomycosis in persons infected with HIV type 1
    Neil M Ampel
    Department of Medicine, University of Arizona College of Medicine and Southern Arizona Veterans Affairs Health Care System, Tucson, Arizona 85723, USA
    Clin Infect Dis 41:1174-8. 2005
  3. pmc The mannose receptor mediates the cellular immune response in human coccidioidomycosis
    Neil M Ampel
    Department of Medicine, University of Arizona Health Sciences Center, Tucson, Arizona, USA
    Infect Immun 73:2554-5. 2005
  4. doi request reprint Mannose-binding lectin serum levels are low in persons with clinically active coccidioidomycosis
    Neil M Ampel
    The Valley Fever Center for Excellence, The University of Arizona College of Medicine, Tucson, AZ 85723, USA
    Mycopathologia 167:173-80. 2009
  5. doi request reprint New perspectives on coccidioidomycosis
    Neil M Ampel
    Division of Infectious Diseases, Department of Medicine, and the Valley Fever Center for Excellence, University of Arizona, Tucson, AZ, USA
    Proc Am Thorac Soc 7:181-5. 2010
  6. ncbi request reprint What's Behind the Increasing Rates of Coccidioidomycosis in Arizona and California?
    Neil M Ampel
    Medical Service 1 111, Southern Arizona Veterans Affairs Health Care System, 3601 South Sixth Avenue, Tucson, AZ, 85723, USA
    Curr Infect Dis Rep 12:211-6. 2010
  7. doi request reprint Factors and outcomes associated with the decision to treat primary pulmonary coccidioidomycosis
    Neil M Ampel
    Department of Medicine, Section of Infectious Diseases, University of Arizona, Tucson, AZ, USA
    Clin Infect Dis 48:172-8. 2009
  8. ncbi request reprint Coccidioidomycosis in persons infected with HIV-1
    Neil M Ampel
    Medical Service 1 111, SAVAHCS, 3601 S Sixth Avenue, Tucson, Arizona 85723, USA
    Ann N Y Acad Sci 1111:336-42. 2007
  9. doi request reprint Coccidioidomycosis: a review of recent advances
    Neil M Ampel
    College of Medicine, University of Arizona, Medical Service 1 111, SAVAHCS, Tucson, AZ 85723, USA
    Clin Chest Med 30:241-51, v. 2009
  10. pmc Preliminary evaluation of whole-blood gamma interferon release for clinical assessment of cellular immunity in patients with active coccidioidomycosis
    Neil M Ampel
    Medicine and Primary Care 1 111, Southern Arizona Veterans Affairs Health Care System, 3601 S Sixth Avenue, Tucson, AZ 85723, USA
    Clin Diagn Lab Immunol 12:700-4. 2005

Collaborators

Detail Information

Publications29

  1. ncbi request reprint The complex immunology of human coccidioidomycosis
    Neil M Ampel
    Medical Service, 1 111, SAVAHCS, 3601 S Sixth Avenue, Tucson, AZ 85723, USA
    Ann N Y Acad Sci 1111:245-58. 2007
    ..These observations could be useful in the development of a human vaccine against coccidiodomycosis...
  2. ncbi request reprint Coccidioidomycosis in persons infected with HIV type 1
    Neil M Ampel
    Department of Medicine, University of Arizona College of Medicine and Southern Arizona Veterans Affairs Health Care System, Tucson, Arizona 85723, USA
    Clin Infect Dis 41:1174-8. 2005
    ..Other manifestations of coccidioidomycosis require prolonged therapy, and life-long treatment is recommended for persons with meningitis...
  3. pmc The mannose receptor mediates the cellular immune response in human coccidioidomycosis
    Neil M Ampel
    Department of Medicine, University of Arizona Health Sciences Center, Tucson, Arizona, USA
    Infect Immun 73:2554-5. 2005
    ..These data suggest that MR mediates IL-2 release by T27K...
  4. doi request reprint Mannose-binding lectin serum levels are low in persons with clinically active coccidioidomycosis
    Neil M Ampel
    The Valley Fever Center for Excellence, The University of Arizona College of Medicine, Tucson, AZ 85723, USA
    Mycopathologia 167:173-80. 2009
    ..Mannose-binding lectin (MBL) is a circulating collectin that is part of the innate immune response. We explored the serum levels of MBL in persons with different forms of coccidioidomycosis...
  5. doi request reprint New perspectives on coccidioidomycosis
    Neil M Ampel
    Division of Infectious Diseases, Department of Medicine, and the Valley Fever Center for Excellence, University of Arizona, Tucson, AZ, USA
    Proc Am Thorac Soc 7:181-5. 2010
    ..However, a recent study suggests that, at least for those with primary pulmonary disease, antifungal therapy may lead to subsequent complications once this therapy is discontinued compared with those who receive no therapy at all...
  6. ncbi request reprint What's Behind the Increasing Rates of Coccidioidomycosis in Arizona and California?
    Neil M Ampel
    Medical Service 1 111, Southern Arizona Veterans Affairs Health Care System, 3601 South Sixth Avenue, Tucson, AZ, 85723, USA
    Curr Infect Dis Rep 12:211-6. 2010
    ..None of these factors are mutually exclusive and none has been clearly established as the etiology for the increase...
  7. doi request reprint Factors and outcomes associated with the decision to treat primary pulmonary coccidioidomycosis
    Neil M Ampel
    Department of Medicine, Section of Infectious Diseases, University of Arizona, Tucson, AZ, USA
    Clin Infect Dis 48:172-8. 2009
    ..Studies that assess the value of initiating oral antifungal therapy to treat primary pulmonary coccidioidomycosis have not been published previously...
  8. ncbi request reprint Coccidioidomycosis in persons infected with HIV-1
    Neil M Ampel
    Medical Service 1 111, SAVAHCS, 3601 S Sixth Avenue, Tucson, Arizona 85723, USA
    Ann N Y Acad Sci 1111:336-42. 2007
    ..The duration of treatment of coccidioidomycosis in those with HIV-1 infection is not established and in many patients it is either prolonged or life-long. Adherence to antiretroviral therapy is important in preventing recurrence...
  9. doi request reprint Coccidioidomycosis: a review of recent advances
    Neil M Ampel
    College of Medicine, University of Arizona, Medical Service 1 111, SAVAHCS, Tucson, AZ 85723, USA
    Clin Chest Med 30:241-51, v. 2009
    ..With this increase in incidence have come new observations and insights and re-examination of past issues. This article explores some of these areas by focusing principally on recent publications that are of importance...
  10. pmc Preliminary evaluation of whole-blood gamma interferon release for clinical assessment of cellular immunity in patients with active coccidioidomycosis
    Neil M Ampel
    Medicine and Primary Care 1 111, Southern Arizona Veterans Affairs Health Care System, 3601 S Sixth Avenue, Tucson, AZ 85723, USA
    Clin Diagn Lab Immunol 12:700-4. 2005
    ..59; P < 0.01). These results suggest that the IFN-gamma release assay with T27K as the antigen may be a useful clinical test for assessing cellular immunity in patients with active coccidioidomycosis...
  11. ncbi request reprint An archived lot of coccidioidin induces specific coccidioidal delayed-type hypersensitivity and correlates with in vitro assays of coccidioidal cellular immune response
    Neil M Ampel
    Department of Medicine, University of Arizona, Tucson, AZ, USA
    Mycopathologia 161:67-72. 2006
    ..01 for both). These data suggest that archived coccidioidin retains its potency and specificity and that in vitro test of coccidioidal immunity may have utility in the measurement of coccidioidal cellular immunity...
  12. pmc Polyfunctional T lymphocytes are in the peripheral blood of donors naturally immune to coccidioidomycosis and are not induced by dendritic cells
    Lance Nesbit
    Department of Immunobiology, University of Arizona, Tucson, Arizona, USA
    Infect Immun 78:309-15. 2010
    ..03). These data demonstrate the presence of polyfunctional T lymphocytes in the peripheral blood of individuals with coccidioidal immunity and suggest a model for the in vitro testing of vaccine candidates for coccidioidomycosis...
  13. doi request reprint Coccidioidomycosis in patients with HIV-1 infection in the era of potent antiretroviral therapy
    Fares Y Masannat
    Division of Infectious Diseases, Department of Medicine, and Valley Fever Center for Excellence, University of Arizona, and Southern Arizona Veterans Affairs Health Care System, Tucson, USA
    Clin Infect Dis 50:1-7. 2010
    ..However, there have been no studies on its incidence or clinical expression during the era of potent antiretroviral therapy...
  14. pmc Spherules derived from Coccidioides posadasii promote human dendritic cell maturation and activation
    Sara O Dionne
    Valley Fever Center for Excellence, Tuscon, AZ, USA
    Infect Immun 74:2415-22. 2006
    ....
  15. pmc Coccidioidomycosis as a common cause of community-acquired pneumonia
    Lisa Valdivia
    University of Arizona College of Medicine, Tucson, Arizona 85723, USA
    Emerg Infect Dis 12:958-62. 2006
    ..If CAP develops in persons who travel or reside in Coccidioides-endemic regions, diagnostic evaluation should routinely include laboratory evaluation for this organism...
  16. doi request reprint Immunological characterization of bronchoalveolar lavage fluid in patients with acute pulmonary coccidioidomycosis
    Lance A Nesbit
    Research Services, Southern Arizona Veterans Affairs Health Care System, USA
    J Infect Dis 208:857-63. 2013
    ..The specific cellular immunological characteristics of bronchoalveolar lavage (BAL) fluid in acute pulmonary coccidioidomycosis have not been defined...
  17. pmc In vitro whole-blood analysis of cellular immunity in patients with active coccidioidomycosis by using the antigen preparation T27K
    Neil M Ampel
    Medicine and Primary Care Service, Southern Arizona Veterans Affairs Health Care System, Tucson, Arizona 85723, USA
    Clin Diagn Lab Immunol 9:1039-43. 2002
    ..001), but not for IL-4, IL-5, or IL-10. These data indicate that in vitro assessment of CD69 expression on T lymphocytes by using T27K may be a useful measure of cellular immune response among subjects with active coccidioidomycosis...
  18. ncbi request reprint Fatigue in coccidioidomycosis. Quantification and correlation with clinical, immunological, and nutritional factors
    Jennifer Muir Bowers
    Valley Fever Center for Excellence and the Department of Medicine of the University of Arizona, and the Southern Arizona Veterans Affairs Health Center System, Tucson, Arizona, USA
    Med Mycol 44:585-90. 2006
    ..078, P=0.261) or serum TNF-alpha (r2=0.028, P=0.504) concentrations. Severe fatigue is a common condition among patients with active coccidioidomycosis and is associated with a declining BMI...
  19. ncbi request reprint Reversal of coccidioidal anergy in vitro by dendritic cells from patients with disseminated coccidioidomycosis
    John O Richards
    Department of Microbiology and Immunology, Arizona Health Sciences Center, Tucson, AZ 85724, USA
    J Immunol 169:2020-5. 2002
    ....
  20. ncbi request reprint In vitro modulation of cytokine production by lymphocytes in human coccidioidomycosis
    Neil M Ampel
    Medicine and Primary Care 1 111, Southern Arizona Veterans Affairs Medical Center, 3601 S Sixth Avenue, Tucson, AZ, USA
    Cell Immunol 221:115-21. 2003
    ..These data demonstrate a differential response to stimulation with the coccidioidal antigen T27K among donors with coccidioidomycosis that can be manipulated by cell type and cytokine environment...
  21. pmc Recent advances in our understanding of the environmental, epidemiological, immunological, and clinical dimensions of coccidioidomycosis
    Chinh Nguyen
    Southern Arizona Veterans Affairs Health Care System, Tucson, Arizona, USA
    Clin Microbiol Rev 26:505-25. 2013
    ..There have been some advances in therapeutics with the increased use of newer azoles. Lastly, there is an overview of the ongoing search for a preventative vaccine...
  22. pmc Cellular immune suppressor activity resides in lymphocyte cell clusters adjacent to granulomata in human coccidioidomycosis
    Lijin Li
    Department of Microbiology and Immunology, University of Arizona, Tucson, Arizona, USA
    Infect Immun 73:3923-8. 2005
    ....
  23. ncbi request reprint Measurement of cellular immunity in human coccidioidomycosis
    Neil M Ampel
    University of Arizona, Southern Arizona Veterans Affairs Health Care System, Tucson, Arizona 85723, USA
    Mycopathologia 156:247-62. 2003
    ..Despite this, a study of a coccidioidal vaccine failed to demonstrate efficacy. Current and future studies are focused on modulating the coccidioidal immune response in vitro and in vivo and on developing an improved vaccine...
  24. ncbi request reprint Combating opportunistic infections: coccidioidomycosis
    Neil M Ampel
    University of Arizona, Southern Arizona Veterans Affairs Medical Center, Tucson, AZ 85723, USA
    Expert Opin Pharmacother 5:255-61. 2004
    ..Intrathecal amphotericin B is required for those cases that fail. Prevention of coccidioidomycosis by environmental control is difficult. In the future, immunisation or immune modulation may offer protection...
  25. ncbi request reprint Increased risk of coccidioidomycosis in patients treated with tumor necrosis factor alpha antagonists
    Laurie Bergstrom
    University of Arizona, Tucson, 85724, USA
    Arthritis Rheum 50:1959-66. 2004
    ....
  26. ncbi request reprint Coccidioidomycosis
    John N Galgiani
    Valley Fever Center for Excellence, Tucson, AZ 85723, USA
    Clin Infect Dis 41:1217-23. 2005
  27. doi request reprint Management of coccidioidomycosis in patients receiving biologic response modifiers or disease-modifying antirheumatic drugs
    Sara Taroumian
    University of California, Los Angeles, CA 90095 1685, USA
    Arthritis Care Res (Hoboken) 64:1903-9. 2012
    ..We conducted a retrospective study of how both concurrent diseases were managed and the patient outcomes at 2 centers in Tucson, Arizona...
  28. ncbi request reprint The solitary pulmonary nodule
    Neil M Ampel
    N Engl J Med 349:1575; author reply 1575. 2003