John Kenneth Amory

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. doi request reprint Levels of the retinoic acid synthesizing enzyme aldehyde dehydrogenase-1A2 are lower in testicular tissue from men with infertility
    John K Amory
    Department of Medicine, University of Washington, Seattle, Washington Electronic address
    Fertil Steril 101:960-6. 2014
  2. doi request reprint Pharmacokinetics of modified slow-release oral testosterone over 9 days in normal men with experimental hypogonadism
    Ada Lee
    Center for Research in Reproduction and Contraception, Divisions of General Internal Medicine and Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington Medical School, Seattle, WA, USA
    J Androl 33:420-6. 2012
  3. ncbi request reprint Endocrine regulation of testicular function in men: implications for contraceptive development
    J K Amory
    Population Center for Research in Reproduction, University of Washington, Seattle, WA, USA
    Mol Cell Endocrinol 182:175-9. 2001
  4. ncbi request reprint Testosterone/progestin regimens: a realistic option for male contraception?
    John K Amory
    University of Washington, Division of General Internal Medicine, Box 356429, 1959 NE Pacific Street, Seattle, WA 98195 USA
    Curr Opin Investig Drugs 5:1025-30. 2004
  5. ncbi request reprint Drug effects on spermatogenesis
    John K Amory
    Center for Research in Reproduction and Contraception, Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    Drugs Today (Barc) 43:717-24. 2007
  6. ncbi request reprint Inhibiting sperm motility for male contraception: will the sperm tail be its "Achilles heel"?
    John K Amory
    Division of General Internal Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA
    Mol Interv 7:68-70. 2007
  7. pmc Serum 17-hydroxyprogesterone strongly correlates with intratesticular testosterone in gonadotropin-suppressed normal men receiving various dosages of human chorionic gonadotropin
    John K Amory
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    Fertil Steril 89:380-6. 2008
  8. ncbi request reprint Contraceptive developments for men
    John K Amory
    Center for Research in Reproduction and Contraception, Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    Drugs Today (Barc) 43:179-92. 2007
  9. ncbi request reprint Oral testosterone in oil plus dutasteride in men: a pharmacokinetic study
    John K Amory
    Center for Research in Reproduction and Contraception, Division of General Internal Medicine, University of Washington Medical School, Box 356429, 1959 NE Pacific Street, Seattle, Washington 98195, USA
    J Clin Endocrinol Metab 90:2610-7. 2005
  10. ncbi request reprint Elevated end-of-treatment serum INSL3 is associated with failure to completely suppress spermatogenesis in men receiving male hormonal contraception
    John K Amory
    Department of Medicine, University of Washington, 1959 NE Pacific, Seattle, WA 98195, USA
    J Androl 28:548-54. 2007

Research Grants

Detail Information

Publications62

  1. doi request reprint Levels of the retinoic acid synthesizing enzyme aldehyde dehydrogenase-1A2 are lower in testicular tissue from men with infertility
    John K Amory
    Department of Medicine, University of Washington, Seattle, Washington Electronic address
    Fertil Steril 101:960-6. 2014
    ..To determine whether decreased testicular levels of enzymes necessary for retinoic acid biosynthesis were associated with male infertility, as retinoic acid is known to be necessary for spermatogenesis...
  2. doi request reprint Pharmacokinetics of modified slow-release oral testosterone over 9 days in normal men with experimental hypogonadism
    Ada Lee
    Center for Research in Reproduction and Contraception, Divisions of General Internal Medicine and Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington Medical School, Seattle, WA, USA
    J Androl 33:420-6. 2012
    ..This formulation of oral testosterone may have efficacy for the treatment of testosterone deficiency...
  3. ncbi request reprint Endocrine regulation of testicular function in men: implications for contraceptive development
    J K Amory
    Population Center for Research in Reproduction, University of Washington, Seattle, WA, USA
    Mol Cell Endocrinol 182:175-9. 2001
    ..Recent promising trials of hormonal contraceptive combinations may soon bring the promise of male contraception to fruition...
  4. ncbi request reprint Testosterone/progestin regimens: a realistic option for male contraception?
    John K Amory
    University of Washington, Division of General Internal Medicine, Box 356429, 1959 NE Pacific Street, Seattle, WA 98195 USA
    Curr Opin Investig Drugs 5:1025-30. 2004
    ..Significant suppression of spermatogenesis is observed in the remainder of individuals. These findings may soon result in the marketing of a safe, reversible and effective hormonal contraceptive for men...
  5. ncbi request reprint Drug effects on spermatogenesis
    John K Amory
    Center for Research in Reproduction and Contraception, Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    Drugs Today (Barc) 43:717-24. 2007
    ..In this paper, we will review the drugs that are known to adversely impact spermatogenesis, and/or sperm function and detail what is known about the mechanisms through which these compounds impair fertility in men...
  6. ncbi request reprint Inhibiting sperm motility for male contraception: will the sperm tail be its "Achilles heel"?
    John K Amory
    Division of General Internal Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA
    Mol Interv 7:68-70. 2007
    ..Future efforts directed towards effectively antagonizing the activities of these or other such targets will be required to completely impair sperm production, function, or both and create a usable male "pill."..
  7. pmc Serum 17-hydroxyprogesterone strongly correlates with intratesticular testosterone in gonadotropin-suppressed normal men receiving various dosages of human chorionic gonadotropin
    John K Amory
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    Fertil Steril 89:380-6. 2008
    ..To determine if serum concentrations of testosterone precursors would correlate with intratesticular testosterone (ITT) concentration measured directly by testicular aspiration and allow for a less invasive means of inferring ITT...
  8. ncbi request reprint Contraceptive developments for men
    John K Amory
    Center for Research in Reproduction and Contraception, Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    Drugs Today (Barc) 43:179-92. 2007
    ....
  9. ncbi request reprint Oral testosterone in oil plus dutasteride in men: a pharmacokinetic study
    John K Amory
    Center for Research in Reproduction and Contraception, Division of General Internal Medicine, University of Washington Medical School, Box 356429, 1959 NE Pacific Street, Seattle, Washington 98195, USA
    J Clin Endocrinol Metab 90:2610-7. 2005
    ..T and D]. The administration of oral T or TE in oil combined with D results in unexpected and potentially therapeutic increases in serum T. Additional studies of this combination as a novel form of oral androgen therapy are warranted...
  10. ncbi request reprint Elevated end-of-treatment serum INSL3 is associated with failure to completely suppress spermatogenesis in men receiving male hormonal contraception
    John K Amory
    Department of Medicine, University of Washington, 1959 NE Pacific, Seattle, WA 98195, USA
    J Androl 28:548-54. 2007
    ..INSL3 may play a role in preventing complete suppression of spermatogenesis in some men on hormonal contraceptive regimens. This finding suggests that INSL3 may be a potential target for male contraceptive development...
  11. ncbi request reprint Male hormonal contraceptives: current status and future prospects
    John K Amory
    Department of Medicine, Center for Research in Reproduction and Contraception, University of Washington, Seattle, Washington 98195, USA
    Treat Endocrinol 4:333-41. 2005
    ....
  12. ncbi request reprint Miglustat has no apparent effect on spermatogenesis in normal men
    J K Amory
    Department of Medicine, University of Washington, Seattle, WA 98195, USA
    Hum Reprod 22:702-7. 2007
    ..This observation suggested that miglustat might have utility for fertility control in man. To ascertain the impact of miglustat on human spermatogenesis, we conducted a pilot study of miglustat administration in normal men...
  13. ncbi request reprint Oral testosterone in oil: pharmacokinetic effects of 5alpha reduction by finasteride or dutasteride and food intake in men
    John K Amory
    University of Washington, Box 356429, 1959 NE Pacific St, Seattle, WA 98195, USA
    J Androl 27:72-8. 2006
    ..Additional studies of the combination of oral T in oil with 5alpha-reductase inhibitors as a novel form of oral T therapy are warranted...
  14. ncbi request reprint Clinical problem-solving. A jaundiced eye
    John K Amory
    Department of Internal Medicine, University of Washington, Seattle, WA 98195, USA
    N Engl J Med 354:1516-20. 2006
  15. ncbi request reprint Male hormonal contraceptives
    J K Amory
    Center for Research in Reproduction and Contraception, Department of Medicine, University of Washington, Seattle, WA 98195, USA
    Minerva Ginecol 58:215-26. 2006
    ....
  16. pmc Pharmacokinetics and pharmacodynamics of oral testosterone enanthate plus dutasteride for 4 weeks in normal men: implications for male hormonal contraception
    John K Amory
    Center for Research in Reproduction and Contraception, University of Washington, Box 356429, 1959 NE Pacific St, Seattle, WA 98195, USA
    J Androl 29:260-71. 2008
    ..The administration of 800 mg oral TE daily combined with dutasteride for 28 days significantly suppresses gonadotropins without untoward side effects and might have utility as part of a male hormonal contraceptive regimen...
  17. ncbi request reprint Drug insight: Recent advances in male hormonal contraception
    John K Amory
    Department of Medicine, University of Washington, Seattle, WA 98195, USA
    Nat Clin Pract Endocrinol Metab 2:32-41. 2006
    ..One of these testosterone and progestogen combination regimens might soon bring the promise of male hormonal contraception to fruition...
  18. ncbi request reprint Preoperative supraphysiological testosterone in older men undergoing knee replacement surgery
    John K Amory
    Department of Medicine, VA Puget Sound Health Care System, Seattle, Washington, USA
    J Am Geriatr Soc 50:1698-701. 2002
    ....
  19. pmc Suppression of spermatogenesis by bisdichloroacetyldiamines is mediated by inhibition of testicular retinoic acid biosynthesis
    John K Amory
    Department of Medicine, University of Washington School of Medicine and School of Pharmaceutics, Seattle, WA 98195, USA
    J Androl 32:111-9. 2011
    ..These findings suggest that ALDH1a2 is a promising target for the development of a reversible, nonhormonal male contraceptive...
  20. ncbi request reprint Testosterone release from a subcutaneous, biodegradable microcapsule formulation (Viatrel) in hypogonadal men
    John K Amory
    Population Center for Research in Reproduction, Geriatric Research Education and Clinical Center, Veteran s Affairs Puget Sound Health Care System, Seattle, Washington, USA
    J Androl 23:84-91. 2002
    ..Subcutaneously administered testosterone microcapsules may provide a safe and convenient method for the long-term treatment of male hypogonadism or testosterone replacement in male contraceptive regimens...
  21. pmc Vasectomy by epithelial curettage without suture or cautery: a pilot study in humans
    John K Amory
    Department of Medicine, Center for Research in Reproduction and Contraception, University of Washington School of Medicine, Seattle, WA 98195, USA
    Asian J Androl 12:315-21. 2010
    ..Epithelial curettage will require further refinement to determine if it is a viable form of vasectomy...
  22. pmc Oral administration of the GnRH antagonist acyline, in a GIPET-enhanced tablet form, acutely suppresses serum testosterone in normal men: single-dose pharmacokinetics and pharmacodynamics
    John Kenneth Amory
    Department of Medicine, Division of General Internal Medicine and Endocrinology, Center for Research in Reproduction and Contraception, University of Washington, Seattle, WA 98195, USA
    Cancer Chemother Pharmacol 64:641-5. 2009
    ..We hypothesized that GIPET enhancement would allow for the safe oral dosing of acyline for the treatment of prostate cancer...
  23. ncbi request reprint Regulation of testicular function in men: implications for male hormonal contraceptive development
    John K Amory
    Department of Medicine, Population Center for Research in Reproduction, University of Washington, Box 356429, 1959 NE Pacific Street, Seattle, WA 98195, USA
    J Steroid Biochem Mol Biol 85:357-61. 2003
    ....
  24. ncbi request reprint Oral testosterone-triglyceride conjugate in rabbits: single-dose pharmacokinetics and comparison with oral testosterone undecanoate
    J K Amory
    Population Center for Research in Reproduction, University of Washington, Seattle, Washington, USA
    J Androl 24:716-20. 2003
    ..TTC may offer an alternative to the use of TU for oral testosterone therapy. Further testing of this compound is warranted...
  25. ncbi request reprint Daily testosterone and gonadotropin levels are similar in azoospermic and nonazoospermic normal men administered weekly testosterone: implications for male contraceptive development
    J K Amory
    Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System and Department of Medicine, University of Washington School of Medicine, Seattle, USA
    J Androl 22:1053-60. 2001
    ..Innate differences in the testicle's ability to maintain spermatogenesis in a low-gonadotropin environment may explain persistent spermatogenesis in some men treated with androgen-based contraceptive regimens...
  26. ncbi request reprint George Washington's infertility: why was the father of our country never a father?
    John K Amory
    Department of Medicine and the Population Center for Research in Human Reproduction, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Fertil Steril 81:495-9. 2004
    ..The author also speculates as to the cause of Washington's infertility and its effect on the course of American history. Frank discussion of Washington's infertility might provide some comfort to men struggling with infertility today...
  27. pmc Progress and prospects in male hormonal contraception
    John K Amory
    Center for Research in Reproduction and Contraception, Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    Curr Opin Endocrinol Diabetes Obes 15:255-60. 2008
    ..Male hormonal contraception is well tolerated and acceptable to most men. Unfortunately, testosterone-alone regimens fail to completely suppress spermatogenesis in all men, meaning that in some the potential for fertility remains...
  28. pmc Hyperthyroidism from autoimmune thyroiditis in a man with type 1 diabetes mellitus: a case report
    John K Amory
    Division of General Internal Medicine, Department of Medicine, University of Washington School of Medicine, 1959 NE Pacific Street, Seattle, WA 98195, USA
    J Med Case Reports 5:277. 2011
    ..abstract:..
  29. ncbi request reprint The effect of 5alpha-reductase inhibition with dutasteride and finasteride on semen parameters and serum hormones in healthy men
    John K Amory
    Department of Medicine, Veterans Affairs Puget Sound Health Care System, University of Washington, Seattle, WA 98195, USA
    J Clin Endocrinol Metab 92:1659-65. 2007
    ..Dutasteride and finasteride are 5alpha-reductase inhibitors (5ARIs) that dramatically reduce serum levels of dihydrotestosterone (DHT)...
  30. ncbi request reprint Acceptability of a combination testosterone gel and depomedroxyprogesterone acetate male contraceptive regimen
    John K Amory
    Department of Medicine, University of Washington, Box 326429, Seattle, WA 98195, USA
    Contraception 75:218-23. 2007
    ....
  31. pmc Combined transdermal testosterone gel and the progestin nestorone suppresses serum gonadotropins in men
    Vahid Mahabadi
    Department of Medicine, Division of Endocrinology, Harbor UCLA Medical Center and Los Angeles Biomedical Research Institute, Torrance, California 90509, USA
    J Clin Endocrinol Metab 94:2313-20. 2009
    ..Nestorone (NES), a progestin without estrogenic or androgenic activity, when combined with T may be an excellent candidate for male contraception...
  32. ncbi request reprint Intratesticular testosterone concentrations comparable with serum levels are not sufficient to maintain normal sperm production in men receiving a hormonal contraceptive regimen
    Andrea D Coviello
    Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
    J Androl 25:931-8. 2004
    ..Intratesticular androgenic bioactivity was higher than ITT during treatment, suggesting that other androgens may be prevalent in the low-ITT environment...
  33. ncbi request reprint Intramuscular testosterone enanthate plus very low dosage oral levonorgestrel suppresses spermatogenesis without causing weight gain in normal young men: a randomized clinical trial
    Bradley D Anawalt
    Department of Medicine, University of Washington School of Medicine, Seattle, WA 98108, USA
    J Androl 26:405-13. 2005
    ....
  34. ncbi request reprint A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in healthy young men
    Karen L Herbst
    Department of Medicine, Division of Endocrinology, Metabolism, and Molecular Medicine, Charles R Drew University, Los Angeles, California 90059, USA
    J Clin Endocrinol Metab 89:5959-65. 2004
    ..A twice monthly injection of acyline could be used as a potent suppressor of the GnRH axis to advance the development of a hormonal male contraceptive or for treatment of hormonally dependent disease...
  35. ncbi request reprint The male contraceptive regimen of testosterone and levonorgestrel significantly increases lean mass in healthy young men in 4 weeks, but attenuates a decrease in fat mass induced by testosterone alone
    Karen L Herbst
    Population Center for Research in Reproduction, Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Clin Endocrinol Metab 88:1167-73. 2003
    ..These findings suggest that androgen-based male hormonal contraceptives might have favorable effects on body composition. The impact of these changes on cardiovascular risk in normal men needs further study...
  36. pmc Treatment of male infertility secondary to morbid obesity
    Mara Y Roth
    Division of Metabolism, Endocrinology and Nutrition, University of Washington School of Medicine, Seattle, WA 98195 6246, USA
    Nat Clin Pract Endocrinol Metab 4:415-9. 2008
    ..5 kg/m(2)). Before referral to the clinic, the patient had been treated with testosterone therapy for 4 months for hypogonadism. This treatment had caused his initially low sperm concentration to fall to undetectable levels...
  37. ncbi request reprint Exogenous testosterone or testosterone with finasteride increases bone mineral density in older men with low serum testosterone
    John K Amory
    Department of Medicine, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98195, USA
    J Clin Endocrinol Metab 89:503-10. 2004
    ..These findings have important implications for the prevention and treatment of osteoporosis in older men with low T levels...
  38. pmc The effect of 5alpha-reductase inhibition with dutasteride and finasteride on bone mineral density, serum lipoproteins, hemoglobin, prostate specific antigen and sexual function in healthy young men
    John K Amory
    Department of Medicine, University of Washington, Seattle, Washington, USA
    J Urol 179:2333-8. 2008
    ..Because androgens affect bone, lipids, hematopoiesis, prostate and sexual function, we determined the impact of 5alpha-reductase inhibitors on these end points...
  39. pmc Advances in male contraception
    Stephanie T Page
    Center for Research in Reproduction and Contraception, Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Endocr Rev 29:465-93. 2008
    ....
  40. ncbi request reprint Testosterone administration to men increases hepatic lipase activity and decreases HDL and LDL size in 3 wk
    Karen L Herbst
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    Am J Physiol Endocrinol Metab 284:E1112-8. 2003
    ..Testosterone is therefore a potent stimulator of hepatic lipase activity, decreasing HDL-C, HDL(2), and HDL(3) as well as increasing LDL particle density changes, all associated with increased cardiovascular risk...
  41. pmc Comparative cognitive and subjective side effects of immediate-release oxycodone in healthy middle-aged and older adults
    Monique M Cherrier
    Department of Psychiatry, School of Medicine, University of Washington, Seattle, Washington, USA
    J Pain 10:1038-50. 2009
    ....
  42. doi request reprint Klinefelter syndrome presenting as behavioral problems in a young adult
    Alexandra M Molnar
    International Medicine Clinic, Harborview Medical Center, Box 359895, 325 9th Avenue, Seattle, WA 98104, USA
    Nat Rev Endocrinol 6:707-12. 2010
    ..A previous physical examination at school revealed the patient to have small, firm testicles which prompted further testing...
  43. pmc Dihydrotestosterone administration does not increase intraprostatic androgen concentrations or alter prostate androgen action in healthy men: a randomized-controlled trial
    Stephanie T Page
    Division of Metabolism, Endocrinology, and Nutrition, University of Washington School of Medicine, Box 357138, 1959 NE Pacific Street, Seattle, Washington 98195, USA
    J Clin Endocrinol Metab 96:430-7. 2011
    ..Exogenous androgens raise serum DHT concentrations, but their effects on the prostate are not clear...
  44. ncbi request reprint Acyline: the first study in humans of a potent, new gonadotropin-releasing hormone antagonist
    Karen L Herbst
    Department of Medicine, Division of Metabolism, University of Washington, Seattle, WA 98195, USA
    J Clin Endocrinol Metab 87:3215-20. 2002
    ..Higher doses of acyline might be effective as depot injections for long-lasting gonadotropin suppression in hormone-dependent diseases and for use in male hormonal contraception regimens...
  45. ncbi request reprint Nanomilled oral testosterone plus dutasteride effectively normalizes serum testosterone in normal men with induced hypogonadism
    Stephanie T Page
    Center for Research in Reproduction and Contraception, Division of General Internal Medicine and Endocrinology, Metabolism, and Nutrition, Department of Medicine, University of Washington Medical School, Seattle, WA, USA
    J Androl 29:222-7. 2008
    ..NmT allows for tablet formulation, and its pharmacokinetics were not affected by food, demonstrating the feasibility of oral nanomilled T as a promising and practical twice-daily therapy for the treatment of male hypogonadism...
  46. ncbi request reprint Clinical problem-solving. Lost in transcription
    Robert M Kalus
    Division of General Internal Medicine, Department of Internal Medicine, University of Washington, Seattle 98104, USA
    N Engl J Med 355:1487-91. 2006
  47. ncbi request reprint Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T
    Stephanie T Page
    Wesley Woods Health Center, 1841 Clifton Road Northeast, Atlanta, Georgia 30329 5102, USA
    J Clin Endocrinol Metab 90:1502-10. 2005
    ....
  48. ncbi request reprint Intratesticular androgens and spermatogenesis during severe gonadotropin suppression induced by male hormonal contraceptive treatment
    Stephanie T Page
    Department of Medicine, University of Washington, Seattle, Washington, USA
    J Androl 28:734-41. 2007
    ..Additional studies to identify factors involved in persistent spermatogenesis despite gonadotropin suppression are warranted...
  49. ncbi request reprint Testosterone administration suppresses adiponectin levels in men
    Stephanie T Page
    Department of Medicine, University of Washington Medical Center, Division of Endocrinology and Metabolism, 1959 NE Pacific, Box 357138, Seattle, WA 98195, USA
    J Androl 26:85-92. 2005
    ..Furthermore, supraphysiologic T administration results in decreased adiponectin levels. Our data support the hypothesis that T, its metabolites, or both directly suppress adipocyte production of adiponectin...
  50. ncbi request reprint Testosterone gel combined with depomedroxyprogesterone acetate is an effective male hormonal contraceptive regimen and is not enhanced by the addition of a GnRH antagonist
    Stephanie T Page
    Department of Medicine, University of Washington, Seattle, Washington 98195, USA
    J Clin Endocrinol Metab 91:4374-80. 2006
    ....
  51. ncbi request reprint Low-dose human chorionic gonadotropin maintains intratesticular testosterone in normal men with testosterone-induced gonadotropin suppression
    Andrea D Coviello
    Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195, USA
    J Clin Endocrinol Metab 90:2595-602. 2005
    ..Extensions of this study will allow determination of the ITT concentration threshold required to maintain spermatogenesis in man...
  52. ncbi request reprint Persistent intraprostatic androgen concentrations after medical castration in healthy men
    Stephanie T Page
    University of Washington Medical Center, Division of Metabolism, Endocrinology and Nutrition, Box 357138, 1959 NE Pacific, Seattle, WA 98195
    J Clin Endocrinol Metab 91:3850-6. 2006
    ..Studies of men with prostate cancer have suggested that prostatic androgens are preserved in the setting of castration. Tissue androgens might stimulate prostate growth, producing adverse clinical consequences...
  53. ncbi request reprint Effect of medical castration on CD4+ CD25+ T cells, CD8+ T cell IFN-gamma expression, and NK cells: a physiological role for testosterone and/or its metabolites
    Stephanie T Page
    Department of Medicine, University of Washington, Seattle, WA, USA
    Am J Physiol Endocrinol Metab 290:E856-63. 2006
    ..In addition, sex steroids suppress NK cell proliferation. This study supports a complex physiological role for T and/or its metabolites in immune regulation...
  54. ncbi request reprint Computer-based order entry decreases duration of indwelling urinary catheterization in hospitalized patients
    Paul B Cornia
    Primary and Specialty Medicine Service, Veterans Affairs Puget Sound Health Care System, and the Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
    Am J Med 114:404-7. 2003
  55. pmc TAC3/TACR3 mutations reveal preferential activation of gonadotropin-releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood
    Elena Gianetti
    Harvard Center for Reproductive Sciences and Reproductive Endocrine Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Clin Endocrinol Metab 95:2857-67. 2010
    ....
  56. ncbi request reprint Novel male hormonal contraceptive combinations: the hormonal and spermatogenic effects of testosterone and levonorgestrel combined with a 5alpha-reductase inhibitor or gonadotropin-releasing hormone antagonist
    Kati L Matthiesson
    Prince Henry s Institute of Medical Research and Department of Obstetrics and Gynaecology, Monash University, Monash Medical Centre, P O Box 5152, Clayton, Victoria 3168, Australia
    J Clin Endocrinol Metab 90:91-7. 2005
    ....
  57. ncbi request reprint Effects of testosterone and levonorgestrel combined with a 5alpha-reductase inhibitor or gonadotropin-releasing hormone antagonist on spermatogenesis and intratesticular steroid levels in normal men
    Kati L Matthiesson
    Prince Henry s Institute of Medical Research, Monash University, Monash Medical Center, Clayton, Victoria 3168, Australia
    J Clin Endocrinol Metab 90:5647-55. 2005
    ..Combination of a GnRH antagonist (acyline), types I and II, 5alpha-reductase inhibitor (dutasteride) or levonorgestrel (LNG) with testosterone (T) treatment may augment the suppression of spermatogenesis and intratesticular (iT) steroids...
  58. ncbi request reprint Male hormonal contraception: suppression of spermatogenesis by injectable testosterone undecanoate alone or with levonorgestrel implants in chinese men
    You lun Gui
    Shanghai Institute of Planned Parenthood Research, 2140 Xie Tu Rd, Shanghai 200032, China
    J Androl 25:720-7. 2004
    ..The combination of high-dose TU every 2 months and LNG implants is a promising candidate for future large-scale efficacy studies of hormonal male contraception in Chinese men...
  59. ncbi request reprint 10th Summit Meeting consensus: recommendations for regulatory approval for hormonal male contraception
    Pertti Aaltonen
    Schering AG, Berlin, Germany
    J Androl 28:362-3. 2007
  60. ncbi request reprint Oral erythromycin and the risk of sudden death
    John K Amory
    N Engl J Med 352:301-4; author reply 301-4. 2005
  61. ncbi request reprint Case 15-2004: cancer therapy and sperm banking
    John K Amory
    N Engl J Med 351:510; author reply 510. 2004
  62. ncbi request reprint Neuroprotection is associated with beta-adrenergic receptor antagonists during cardiac surgery: evidence from 2,575 patients
    David W Amory
    Division of Cardiothoracic Anesthesiology, Department of Anesthesiology, Duke University Heart Center, Durham, NC 27710, USA
    J Cardiothorac Vasc Anesth 16:270-7. 2002
    ..To determine the impact of perioperative beta-adrenergic receptor (betaAR) antagonist administration on neurologic complications...

Research Grants2

  1. Oral Androgen Administration and Function in Man
    JOHN AMORY; Fiscal Year: 2007
    ..Matsumoto M.D., Director, Clinical Research Unit VA-Puget Sound and Professor of Medicine, University of Washington School of Medicine will co-mentor this award. ..