Research Topics
Species | R M AmasinoSummaryAffiliation: University of Wisconsin Country: USA Publications
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Publications
FLOWERING LOCUS C-dependent and -independent regulation of the circadian clock by the autonomous and vernalization pathwaysNeeraj Salathia
Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
BMC Plant Biol 6:10. 2006..Its activity is regulated by many regulatory genes in the "autonomous" and vernalization-dependent flowering pathways. We tested whether these same pathways affect the circadian system...
A physical map of Brassica oleracea shows complexity of chromosomal changes following recursive paleopolyploidizationsXiyin Wang
Plant Genome Mapping Laboratory, University of Georgia, Athens, 30602, USA
BMC Genomics 12:470. 2011..Evolution of the Brassica species has been recursively affected by polyploidy events, and comparison to their relative, Arabidopsis thaliana, provides means to explore their genomic complexity...- 1955: kinetin arrives: the 50th anniversary of a new plant hormoneRichard Amasino
Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706, USA
Plant Physiol 138:1177-84. 2005 - Floral induction and monocarpic versus polycarpic life historiesRichard Amasino
Department of Biocemistry, University of Wisconsin, Babcock Drive, Madison, WI 53706 1544, USA
Genome Biol 10:228. 2009..Recent work in Arabis alpina, a perennial relative of Arabidopsis, has uncovered subtle differences in control of a gene that represses flowering which contributes to the polycarpic habit... - Vernalization, competence, and the epigenetic memory of winterRichard Amasino
Department of Biochemistry, University of Wisconsin, Madison, WI 53706-1544, USA
Plant Cell 16:2553-9. 2004 
Vernalization and flowering timeRichard M Amasino
Department of Biochemistry, University of Wisconsin Madison, 433 Babcock Drive, Madison, WI 53706, USA
Curr Opin Biotechnol 16:154-8. 2005..This epigenetic silencing results from the modification of the chromatin of flowering repressors...- Control of flowering time in plantsR M Amasino
Department of Biochemistry, University of Wisconsin Madison, 420 Henry Mall, Madison, 53706 1569, USA
Curr Opin Genet Dev 6:480-7. 1996..Several genes that regulate flowering time have been molecularly identified and the effects of altered expression of these genes have contributed greatly to understanding their role in flowering... 
Seasonal and developmental timing of floweringRichard Amasino
Department of Biochemistry, University of Wisconsin, Madison, WI, USA
Plant J 61:1001-13. 2010..Arabidopsis research has contributed greatly to understanding these systems at a molecular level...- Identification of a MADS-box gene, FLOWERING LOCUS M, that represses floweringK C Scortecci
Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, WI 53706-1544, USA
Plant J 26:229-36. 2001..FLM overexpression produces late-flowering plants. Thus FLM acts as an inhibitor of flowering. FLM is expressed in areas of cell division such as root and shoot apical regions and leaf primordia... - Loss of FLOWERING LOCUS C activity eliminates the late-flowering phenotype of FRIGIDA and autonomous pathway mutations but not responsiveness to vernalizationS D Michaels
Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, Wisconsin 53706-1544, USA
Plant Cell 13:935-41. 2001..Thus, FRI and the autonomous pathway may act solely to regulate FLC expression, whereas vernalization is able to promote flowering via FLC-dependent and FLC-independent mechanisms... - PAF1-complex-mediated histone methylation of FLOWERING LOCUS C chromatin is required for the vernalization-responsive, winter-annual habit in ArabidopsisYuehui He
Department of Biochemistry and Program in Cellular and Molecular Biology, University of Wisconsin, Madison, Wisconsin 53706, USA
Genes Dev 18:2774-84. 2004..A model of the role of ELF7, ELF8, and other previously described genes in the modification of the chromatin of flowering repressors is presented... - FPA, a gene involved in floral induction in Arabidopsis, encodes a protein containing RNA-recognition motifsF M Schomburg
Department of Biochemistry, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
Plant Cell 13:1427-36. 2001..Overexpression of FPA in Arabidopsis causes early flowering in noninductive short days and creates plants that exhibit a more day-neutral flowering behavior... - Vernalization: a model for investigating epigenetics and eukaryotic gene regulation in plantsRobert J Schmitz
Laboratory of Genetics, University of Wisconsin, Madison, WI 53706, USA
Biochim Biophys Acta 1769:269-75. 2007.... - Identification of a promoter region responsible for the senescence-specific expression of SAG12Y S Noh
Department of Biochemistry, University of Wisconsin, Madison 53706 1544, USA
Plant Mol Biol 41:181-94. 1999..Extracts from young and senescent Arabidopsis leaves contain factors that exhibit differential binding to the senescence-responsive promoter element... - Vernalization in Arabidopsis thaliana is mediated by the PHD finger protein VIN3Sibum Sung
Department of Biochemistry, University of Wisconsin Madison, 433 Babcock Drive, Madison, Wisconsin 53706, USA
Nature 427:159-64. 2004..Here we identify a gene with a function in the measurement of the duration of cold exposure and in the establishment of the vernalized state. We show that this silencing involves changes in the modification of histones in FLC chromatin... - Senescence is induced in individually darkened Arabidopsis leaves, but inhibited in whole darkened plantsL M Weaver
Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, WI 53706, USA
Plant Physiol 127:876-86. 2001..These observations imply that the light status of the entire plant affects the senescence of individual leaves. A model summarizing the results is presented... - The Arabidopsis flowering-time gene LUMINIDEPENDENS is expressed primarily in regions of cell proliferation and encodes a nuclear protein that regulates LEAFY expressionM J Aukerman
Department of Biochemistry, University of Wisconsin, Madison 53706 1544, USA
Plant J 18:195-203. 1999..These data are consistent with the idea that at least one function of LD is to participate in the regulation of LFY... - Histone arginine methylation is required for vernalization-induced epigenetic silencing of FLC in winter-annual Arabidopsis thalianaRobert J Schmitz
Laboratory of Genetics and Department of Biochemistry, University of Wisconsin, Madison, WI 53706, USA
Proc Natl Acad Sci U S A 105:411-6. 2008..Furthermore, the levels of arginine methylation of FLC chromatin increase after vernalization. Therefore, arginine methylation of FLC chromatin is part of the histone code that is required for mitotic stability of the vernalized state... - Regulation of flowering time by histone acetylation in ArabidopsisYuehui He
Department of Biochemistry, University of Wisconsin, Madison, WI 53706, USA
Science 302:1751-4. 2003..However, not all autonomous-pathway mutants exhibit FLC hyperacetylation, indicating that multiple means exist by which this pathway represses FLC expression... - Molecular genetic studies of the memory of winterSibum Sung
Department of Biochemistry, University of Wisconsin at Madison, Madison, WI 53706, USA
J Exp Bot 57:3369-77. 2006..The nature of this epigenetic switch in Arabidopsis thaliana is discussed here... - Delivering copper within plant cellsE Himelblau
Department of Biochemistry, University of Wisconsin, Madison, WI 53706, USA
Curr Opin Plant Biol 3:205-10. 2000..The pathway may also facilitate the transport of copper from senescing leaf tissue. In addition, several other genes have been identified recently that may have a role in copper salvage during senescence... - ARABIDOPSIS TRITHORAX-RELATED7 is required for methylation of lysine 4 of histone H3 and for transcriptional activation of FLOWERING LOCUS CYosuke Tamada
Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706 1544, USA
Plant Cell 21:3257-69. 2009..We show that the flowering phenotype of atx1 atxr7 double mutants is additive relative to those of single mutants. Therefore, both classes of H3K4 methylases appear to be required for proper regulation of FLC expression... - A single amino acid change in the enhancer of zeste ortholog CURLY LEAF results in vernalization-independent, rapid flowering in ArabidopsisMark R Doyle
Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706 1544, USA
Plant Physiol 151:1688-97. 2009..Furthermore, FRI appears to affect CLF occupancy at FLC; thus, our work provides insight into the molecular role that FRI plays in delaying the onset of flowering... - FRIGIDA-ESSENTIAL 1 interacts genetically with FRIGIDA and FRIGIDA-LIKE 1 to promote the winter-annual habit of Arabidopsis thalianaRobert J Schmitz
Laboratory of Genetics, University of Wisconsin, Madison, WI 53706, USA
Development 132:5471-8. 2005.... - Role of chromatin modification in flowering-time controlYuehui He
Department of Biochemistry, University of Wisconsin, Madison, WI 53706, USA
Trends Plant Sci 10:30-5. 2005..These chromatin modifications provide an additional level of regulation of gene expression beyond that of the transcription factors that recruit RNA polymerase to target genes... - Integration of flowering signals in winter-annual ArabidopsisScott D Michaels
Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706, USA
Plant Physiol 137:149-56. 2005..Thus, the integration of flowering signals from the photoperiod and vernalization pathways occurs, at least in part, through the regulation of FT, TSF, and SOC1... - Remembering winter: toward a molecular understanding of vernalizationSibum Sung
Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706, USA
Annu Rev Plant Biol 56:491-508. 2005..Recent work has demonstrated that covalent modifications of histones in the chromatin of target loci are part of the molecular mechanism by which certain repressors are silenced during vernalization... - Lesions in the mRNA cap-binding gene ABA HYPERSENSITIVE 1 suppress FRIGIDA-mediated delayed flowering in ArabidopsisIsabel C Bezerra
Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, WI 53706 1544, USA
Plant J 40:112-9. 2004..The abh1 lesion affects several developmental processes, perhaps because the processing of certain mRNAs in these pathways is more sensitive to loss of cap-binding activity than the majority of cellular mRNAs... - EARLY FLOWERING 5 acts as a floral repressor in ArabidopsisYoo Sun Noh
Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin, Madison, WI 53706 1544, USA
Plant J 38:664-72. 2004..elf5 mutations also partially suppress photoperiod-pathway mutants, and this, along with the ability of elf5 mutations to cause early flowering in short days, indicates that ELF5 also affects flowering independently of FLC... - Vernalization and epigenetics: how plants remember winterSibum Sung
Department of Biochemistry, University of Wisconsin Madison, 53706, USA
Curr Opin Plant Biol 7:4-10. 2004..VIN3 is involved in initiating the modification of FLC chromatin structure. The stable silencing of FLC also requires the DNA-binding protein VERNALIZATION1 (VRN1) and the polycomb-group protein VRN2... - Defending science education against intelligent design: a call to actionAlan D Attie
Department of Biochemistry, University of Wisconsin Madison, Madison, Wisconsin 53706 1544, USA
J Clin Invest 116:1134-8. 2006..Finally, we provide some model legislation that has been introduced in Wisconsin to strengthen the teaching of science... - Senescence-associated vacuoles with intense proteolytic activity develop in leaves of Arabidopsis and soybeanMarisa S Otegui
Instituto de Fisiología Vegetal INFIVE, Universidad Nacional de La Plata, c c 327, 1900, La Plata, Argentina
Plant J 41:831-44. 2005..The presence of two types of vacuoles in senescing leaves could provide different lytic compartments for the dismantling of specific cellular components. The possible origin and functions of SAVs during leaf senescence are discussed... - Isolation of LUMINIDEPENDENS: a gene involved in the control of flowering time in ArabidopsisI Lee
Department of Biochemistry, University of Wisconsin, Madison 53706 1569
Plant Cell 6:75-83. 1994..Genomic and cDNA clones of the LD gene were characterized. The predicted amino acid sequence of the LD protein contains 953 residues and includes two putative bipartite nuclear localization signals and a glutamine-rich region... - Diverse range of gene activity during Arabidopsis thaliana leaf senescence includes pathogen-independent induction of defense-related genesB F Quirino
Department of Biochemistry, University of Wisconsin, Madison 53706, USA
Plant Mol Biol 40:267-78. 1999..Our data indicate that the induction of certain genes involved in plant defense responses is a component of the leaf senescence program... - HUA2 is required for the expression of floral repressors in Arabidopsis thalianaMark R Doyle
Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin, Madison, WI 53706 1544, USA
Plant J 41:376-85. 2005..hua2 mutations suppress late flowering by reducing the expression of several MADS genes that act as floral repressors including FLOWERING LOCUS C (FLC ) and FLOWERING LOCUS M (FLM )... - Overexpression of a novel class of gibberellin 2-oxidases decreases gibberellin levels and creates dwarf plantsFritz M Schomburg
Department of Biochemistry, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
Plant Cell 15:151-63. 2003.... - DICER-LIKE 1 and DICER-LIKE 3 redundantly act to promote flowering via repression of FLOWERING LOCUS C in Arabidopsis thalianaRobert J Schmitz
Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706, USA
Genetics 176:1359-62. 2007..This delayed-flowering phenotype is similar to that of autonomous-pathway mutants, and the flowering delay can be overcome by vernalization... - AGL24 acts as a promoter of flowering in Arabidopsis and is positively regulated by vernalizationScott D Michaels
Department of Biochemistry, University of Wisconsin Madison, Madison, WI 53706, USA
Plant J 33:867-74. 2003..When overexpressed, SOC1 and AGL24 are able to upregulate each other's expression. Thus, AGL24 represents another component in a network of MADS-domain-containing transcription factors that regulate flowering time... - PIE1, an ISWI family gene, is required for FLC activation and floral repression in ArabidopsisYoo Sun Noh
Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin, Madison, Wisconsin 53706 1544, USA
Plant Cell 15:1671-82. 2003..PIE1 also plays a role in petal development, as revealed by the suppression of petal defects of the curly leaf mutant by the pie1 mutation... - A PHD finger protein involved in both the vernalization and photoperiod pathways in ArabidopsisSibum Sung
Department of Biochemistry, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
Genes Dev 20:3244-8. 2006..In addition, VIL1 regulates FLM independently of VIN3 in a photoperiod-dependent manner... - Attenuation of FLOWERING LOCUS C activity as a mechanism for the evolution of summer-annual flowering behavior in ArabidopsisScott D Michaels
Department of Biochemistry, University of Wisconsin, Madison, WI 53706, USA
Proc Natl Acad Sci U S A 100:10102-7. 2003..Sequence analysis indicates that these weak alleles of FLC have arisen independently at least twice during the course of evolution... - Genetic interactions between FLM and other flowering-time genes in Arabidopsis thalianaKatia Scortecci
Department of Biochemistry of Wisconsin, 433 Babcock Drive, Madison, WI 53706-1544, USA
Plant Mol Biol 52:915-22. 2003..Thus FLM and SVP are in the same flowering pathway which interacts with the photoperiod pathway... - Identification of a functional homolog of the yeast copper homeostasis gene ATX1 from ArabidopsisE Himelblau
Department of Biochemistry, University of Wisconsin, 420 Henry Mall, Madison, Wisconsin 53706, USA
Plant Physiol 117:1227-34. 1998..In excised leaves and whole plants treated with high levels of exogenous CuSO4, CCH mRNA levels decreased, indicating that CCH is regulated differently than characterized metallothionein proteins in Arabidopsis... - Inhibition of leaf senescence by autoregulated production of cytokininS Gan
Department of Biochemistry, University of Wisconsin, Madison, 53706 1569, USA
Science 270:1986-8. 1995..This result demonstrates that endogenously produced cytokinin can regulate senescence and provides a system to specifically manipulate the senescence program... - The ELF4 gene controls circadian rhythms and flowering time in Arabidopsis thalianaMark R Doyle
Department of Biochemistry and Program in Cellular and Molecular Biology, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
Nature 419:74-7. 2002..Mutations in elf4 result in early flowering in non-inductive photoperiods, which is probably caused by elevated amounts of CONSTANS (CO), a gene that promotes floral induction... - Acceleration of flowering during shade avoidance in Arabidopsis alters the balance between FLOWERING LOCUS C-mediated repression and photoperiodic induction of floweringAmanda C Wollenberg
Graduate Program in Cellular and Molecular Biology, University of Wisconsin, Madison, Wisconsin 53706, USA
Plant Physiol 148:1681-94. 2008..Finally, our analysis of the contribution of PHYTOCHROME AND FLOWERING TIME1 (PFT1) to shade-mediated rapid flowering has led us to suggest a new model for the involvement of PFT1 in light signaling... - FRIGIDA-related genes are required for the winter-annual habit in ArabidopsisScott D Michaels
Department of Biochemistry, University of Wisconsin, Madison, WI 53706, USA
Proc Natl Acad Sci U S A 101:3281-5. 2004..FRI and FRL1 belong to a seven-member gene family in Arabidopsis, and FRI, FRL1, and at least one additional family member, FRIGIDA LIKE 2 (FRL2), are in a clade of this family that is required for the winter-annual habit in Arabidopsis... - Flowering time: a pathway that begins at the 3' endRichard M Amasino
Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, WI 53706-1544, USA
Curr Biol 13:R670-2. 2003.... - Epigenetic maintenance of the vernalized state in Arabidopsis thaliana requires LIKE HETEROCHROMATIN PROTEIN 1Sibum Sung
Department of Biochemistry, University of Wisconsin at Madison, Madison, Wisconsin, USA
Nat Genet 38:706-10. 2006..LHP1 is enriched at FLC chromatin after prolonged exposure to cold, and LHP1 activity is needed to maintain the increased levels of H3K9 dimethylation at FLC chromatin that are characteristic of the vernalized state... - The WiscDsLox T-DNA collection: an arabidopsis community resource generated by using an improved high-throughput T-DNA sequencing pipelineScott T Woody
Horticulture Department and Genome Center of Wisconsin, University of Wisconsin Madison, Madison, WI 53706, USA
J Plant Res 120:157-65. 2007..Experiments to characterize the utility of the Ds transposon and Cre/Lox elements present in the WiscDsLox lines are in progress and will be reported in the future... - Arabidopsis relatives of the human lysine-specific Demethylase1 repress the expression of FWA and FLOWERING LOCUS C and thus promote the floral transitionDanhua Jiang
Department of Biological Sciences, National University of Singapore, Singapore 117543, Republic of Singapore
Plant Cell 19:2975-87. 2007..Loss of function of LDL1 and LDL2 affects DNA methylation on FWA, whereas FLC repression does not appear to involve DNA methylation; thus, members of the LDL family can participate in a range of silencing mechanisms... - Attenuation of brassinosteroid signaling enhances FLC expression and delays floweringMalgorzata A Domagalska
Max Planck Institute for Plant Breeding Research, Carl von Linne Weg 10, 50829 Cologne, Germany
Development 134:2841-50. 2007..In conclusion, we propose that BR signaling acts to repress FLC expression, particularly in genetic situations, with, for example, dominant FRI alleles or autonomous-pathway mutants, in which FLC is activated... - A complex genetic interaction between Arabidopsis thaliana TOC1 and CCA1/LHY in driving the circadian clock and in output regulationZhaojun Ding
Max Planck Institute for Plant Breeding Research, Cologne, Germany
Genetics 176:1501-10. 2007.... - ELF4 is required for oscillatory properties of the circadian clockHarriet G McWatters
Department of Plant Sciences, University of Oxford, Oxford OX1 3RB, United Kingdom
Plant Physiol 144:391-401. 2007..ELF4, therefore, can be considered a component of the central CCA1/LHY-TOC1 feedback loop in the plant circadian clock... - The TIME FOR COFFEE gene maintains the amplitude and timing of Arabidopsis circadian clocksAnthony Hall
Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom
Plant Cell 15:2719-29. 2003..In contrast to tic and elf3 single mutants, tic elf3 double mutants are completely arrhythmic. Even the robust circadian clock of plants cannot function with defects at two different phases... - Evolutionary conservation of the FLOWERING LOCUS C-mediated vernalization response: evidence from the sugar beet (Beta vulgaris)Patrick A Reeves
United States Department of Agriculture, Agricultural Research Service, National Center for Genetic Resources Preservation, Fort Collins, Colorado 80521, USA
Genetics 176:295-307. 2007..Cold-induced downregulation of an FLC-like floral repressor may be a central feature of the vernalization response in at least half of eudicot species... - Divergent roles of a pair of homologous jumonji/zinc-finger-class transcription factor proteins in the regulation of Arabidopsis flowering timeBosl Noh
Kumho Life and Environmental Science Laboratory, Puk Gu, Kwangju 500 712, Korea
Plant Cell 16:2601-13. 2004..This report demonstrates the in vivo functions of this class of proteins in higher eukaryotes...
Research Grants
- Vernalization a cold-induced regulatory network establishing cellular memoryRichard M Amasino; Fiscal Year: 2010..A general understanding of epigenetic regulation in a range of multi-cellular organisms should ultimately contribute to the development of strategies to treat disease states. ..
- Vernalization a cold-induced regulatory network establishing cellular memoryRichard Amasino; Fiscal Year: 2007..A general understanding of epigenetic regulation in a range of multi-cellular organisms should ultimately contribute to the development of strategies to treat disease states. ..
- Vernalization a cold-induced regulatory network establishing cellular memoryRichard Amasino; Fiscal Year: 2009..A general understanding of epigenetic regulation in a range of multi-cellular organisms should ultimately contribute to the development of strategies to treat disease states. ..