N J Alperin

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. ncbi request reprint Magnetic resonance imaging-based measurements of cerebrospinal fluid and blood flow as indicators of intracranial compliance in patients with Chiari malformation
    Noam Alperin
    Department of Radiology, University of Illinois at Chicago, 60612, USA
    J Neurosurg 103:46-52. 2005
  2. ncbi request reprint MR-Intracranial pressure (ICP): a method to measure intracranial elastance and pressure noninvasively by means of MR imaging: baboon and human study
    N J Alperin
    Departments of Radiology, University of Illinois at Chicago, 1740 W Taylor, Chicago, IL 60612, USA
    Radiology 217:877-85. 2000
  3. ncbi request reprint Analysis of magnetic resonance imaging-based blood and cerebrospinal fluid flow measurements in patients with Chiari I malformation: a system approach
    N Alperin
    Department of Radiology, Neurosurgery, University of Illinois, Chicago, Illinois 60612, USA
    Neurosurg Focus 11:E6. 2001
  4. ncbi request reprint Relationship between total cerebral blood flow and ICP measured noninvasively with dynamic MRI technique in healthy subjects
    N Alperin
    Department of Radiology, The University of Illinois at Chicago, 60612, USA
    Acta Neurochir Suppl 95:191-3. 2005
  5. ncbi request reprint MRI study of cerebral blood flow and CSF flow dynamics in an upright posture: the effect of posture on the intracranial compliance and pressure
    N Alperin
    Department of Radiology, The University of Illinois at Chicago, 60612, USA
    Acta Neurochir Suppl 95:177-81. 2005
  6. ncbi request reprint Evidence for the importance of extracranial venous flow in patients with idiopathic intracranial hypertension (IIH)
    N Alperin
    Department of Radiology, University of Illinois at Chicago, Chicago IL 60612, USA
    Acta Neurochir Suppl 95:129-32. 2005
  7. ncbi request reprint Quantifying the effect of posture on intracranial physiology in humans by MRI flow studies
    Noam Alperin
    Department of Radiology, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Magn Reson Imaging 22:591-6. 2005
  8. ncbi request reprint PUBS: pulsatility-based segmentation of lumens conducting non-steady flow
    Noam Alperin
    Department of Radiology and Bioengineering, University of Illinois Chicago, Chicago, Illinois, USA
    Magn Reson Med 49:934-44. 2003
  9. doi request reprint Noninvasive intracranial compliance from MRI-based measurements of transcranial blood and CSF flows: indirect versus direct approach
    Rong Wen Tain
    Physiological Imaging and Modeling Laboratory, Department of Radiology and Bioengineering, University of Illinois at Chicago, Chicago, IL 60612, USA
    IEEE Trans Biomed Eng 56:544-51. 2009
  10. ncbi request reprint Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical study
    Ben Roitberg
    Department of Neurosurgery M C 799, University of Illinois at Chicago, 912 S Wood St, Chicago, IL 60612, USA
    Neurol Res 25:68-78. 2003

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Magnetic resonance imaging-based measurements of cerebrospinal fluid and blood flow as indicators of intracranial compliance in patients with Chiari malformation
    Noam Alperin
    Department of Radiology, University of Illinois at Chicago, 60612, USA
    J Neurosurg 103:46-52. 2005
    ....
  2. ncbi request reprint MR-Intracranial pressure (ICP): a method to measure intracranial elastance and pressure noninvasively by means of MR imaging: baboon and human study
    N J Alperin
    Departments of Radiology, University of Illinois at Chicago, 1740 W Taylor, Chicago, IL 60612, USA
    Radiology 217:877-85. 2000
    ..To develop a noninvasive method for intracranial elastance and intracranial pressure (ICP) measurement...
  3. ncbi request reprint Analysis of magnetic resonance imaging-based blood and cerebrospinal fluid flow measurements in patients with Chiari I malformation: a system approach
    N Alperin
    Department of Radiology, Neurosurgery, University of Illinois, Chicago, Illinois 60612, USA
    Neurosurg Focus 11:E6. 2001
    ..The authors' group has used dynamic phase-contrast MR imaging to visualize and quantify pulsatile blood and cerebrospinal fluid (CSF) flow in the craniospinal system...
  4. ncbi request reprint Relationship between total cerebral blood flow and ICP measured noninvasively with dynamic MRI technique in healthy subjects
    N Alperin
    Department of Radiology, The University of Illinois at Chicago, 60612, USA
    Acta Neurochir Suppl 95:191-3. 2005
    ..The relationship between the inter-individual CBF and ICP measurements suggest that in the healthy state and in rest these parameters are not correlated...
  5. ncbi request reprint MRI study of cerebral blood flow and CSF flow dynamics in an upright posture: the effect of posture on the intracranial compliance and pressure
    N Alperin
    Department of Radiology, The University of Illinois at Chicago, 60612, USA
    Acta Neurochir Suppl 95:177-81. 2005
    ..This work demonstrates the ability to quantify neurophysiologic parameters associated with regulation of cerebral hemodynamics and hydrodynamics from dynamic MR imaging of blood and CSF flows...
  6. ncbi request reprint Evidence for the importance of extracranial venous flow in patients with idiopathic intracranial hypertension (IIH)
    N Alperin
    Department of Radiology, University of Illinois at Chicago, Chicago IL 60612, USA
    Acta Neurochir Suppl 95:129-32. 2005
    ..5 to 13 mmHg. Findings from this study suggest that increased ICP in some IIH patients could be associated with increased extracranial resistance to cerebral venous outflow...
  7. ncbi request reprint Quantifying the effect of posture on intracranial physiology in humans by MRI flow studies
    Noam Alperin
    Department of Radiology, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Magn Reson Imaging 22:591-6. 2005
    ..To quantify the effect of posture on intracranial physiology in humans by MRI, and demonstrate the relationship between intracranial compliance (ICC) and pressure (ICP), and the pulsatility of blood and CSF flows...
  8. ncbi request reprint PUBS: pulsatility-based segmentation of lumens conducting non-steady flow
    Noam Alperin
    Department of Radiology and Bioengineering, University of Illinois Chicago, Chicago, Illinois, USA
    Magn Reson Med 49:934-44. 2003
    ..There was significantly less measurement variability with the PUBS method. An average fourfold reduction in interobserver measurement variability was obtained with the new method...
  9. doi request reprint Noninvasive intracranial compliance from MRI-based measurements of transcranial blood and CSF flows: indirect versus direct approach
    Rong Wen Tain
    Physiological Imaging and Modeling Laboratory, Department of Radiology and Bioengineering, University of Illinois at Chicago, Chicago, IL 60612, USA
    IEEE Trans Biomed Eng 56:544-51. 2009
    ..The simulations demonstrated that amplitude-based measures of ICC are considerably more sensitive than phase-based measures, and among the amplitude-based measures, the ICC index provides the most reliable estimate of ICC...
  10. ncbi request reprint Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical study
    Ben Roitberg
    Department of Neurosurgery M C 799, University of Illinois at Chicago, 912 S Wood St, Chicago, IL 60612, USA
    Neurol Res 25:68-78. 2003
    ..Our model may be particularly suitable for studies testing the effects of therapeutic strategies involving neural or stem cell transplantation, trophic factors or gene therapy...
  11. ncbi request reprint Evaluating the effect of decompression surgery on cerebrospinal fluid flow and intracranial compliance in patients with chiari malformation with magnetic resonance imaging flow studies
    Anusha Sivaramakrishnan
    Department of Radiology, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Neurosurgery 55:1344-50; discussion 1350-1. 2004
    ..Studying the effect of decompression surgery may improve our understanding of the pathophysiological characteristics of Chiari I malformation and aid in identifying patients who will benefit from the procedure...
  12. ncbi request reprint Noninvasive intracranial compliance and pressure based on dynamic magnetic resonance imaging of blood flow and cerebrospinal fluid flow: review of principles, implementation, and other noninvasive approaches
    Patricia B Raksin
    Department of Neurosurgery, Rush Presbyterian St Luke s Medical Center, Cook County Hospital, Illinois, USA
    Neurosurg Focus 14:e4. 2003
    ..Magnetic resonance imaging-based ICP measurement may prove valuable in the diagnosis and serial evaluation of patients with a variety of disorders associated with alterations in ICP...
  13. ncbi request reprint MR-intracranial compliance and pressure: a method for noninvasive measurement of important neurophysiologic parameters
    Noam Alperin
    Department of Radiology, The University of Illinois at Chicago, 60612, USA
    Methods Enzymol 386:323-49. 2004
  14. ncbi request reprint Early experience from the application of a noninvasive magnetic resonance imaging-based measurement of intracranial pressure in hydrocephalus
    Roberta P Glick
    Department of Neurosurgery, Cook County Hospital and Rush University Medical Center, Chicago, Illinois, USA
    Neurosurgery 59:1052-60; discussion 1060-1. 2006
    ..An early assessment of the potential clinical usefulness of a noninvasive magnetic resonance imaging-based measurement of ICP (MR-ICP) in symptomatic hydrocephalic patients is reported...
  15. pmc Influence of the compliance of the neck arteries and veins on the measurement of intracranial volume change by phase-contrast MRI
    Rong Wen Tain
    Department of Radiology, University of Miami, Miami, Florida 33136, USA
    J Magn Reson Imaging 30:878-83. 2009
    ..To assess the influence of arterial and venous vascular compliances in the neck region on the measurement of the change in intracranial volume during the cardiac cycle...
  16. ncbi request reprint Noncommunicating cysts and cerebrospinal fluid flow dynamics in a patient with a Chiari I malformation and syringomyelia--part II
    Terry Lichtor
    Department of Neurological Surgery, Rush University Medical Center, Chicago, IL 60612, USA
    Spine (Phila Pa 1976) 30:1466-72. 2005
  17. ncbi request reprint Noncommunicating cysts and cerebrospinal fluid flow dynamics in am patient with a Chiari I malformation and syringomyelia--part I
    Terry Lichtor
    Department of Neurological Surgery, Rush University Medical Center, John H Stroger Hospital of Cook County and Hektoen Institute for Medical Research, Chicago, IL 60612, USA
    Spine (Phila Pa 1976) 30:1335-40. 2005
  18. doi request reprint Relationship between ventricular morphology and aqueductal cerebrospinal fluid flow in healthy and communicating hydrocephalus
    William W Chiang
    Departments of Radiology, University of Illinois, Chicago, Illinois 60612, USA
    Invest Radiol 44:192-9. 2009
    ..This work aims to determine the role of anatomic and hydrodynamic factors in modulating the magnitude of CSF flow through the aqueduct...
  19. ncbi request reprint Assessment of cerebrospinal fluid outflow resistance
    Anders Eklund
    Department of Biomedical Engineering and Informatics, Umea University Hospital, 90185 Umea, Sweden
    Med Biol Eng Comput 45:719-35. 2007
    ....
  20. ncbi request reprint Characterization of volumetric flow rate waveforms in the normal internal carotid and vertebral arteries
    Matthew D Ford
    Imaging Research Labs, Robarts Research Institute and Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada
    Physiol Meas 26:477-88. 2005
    ..This capability may be of particular utility for studies where cerebrovascular flow dynamics are required, but only average flow rates are available...
  21. ncbi request reprint Magnetic resonance imaging of the levator veli palatini muscle during speech
    Sandra L Ettema
    Medical Scholars Program, University of Illinois at Urbana Champaign, 61820, USA
    Cleft Palate Craniofac J 39:130-44. 2002
    ..To obtain detailed anatomic information on the levator veli palatini (LVP) muscle from magnetic resonance imaging (MRI). Quantitative measures of the configuration of the LVP muscle at rest and during speech activities were obtained...

Research Grants3

  1. Noninvasive Measurements of Intracranial Pressure
    Noam Alperin; Fiscal Year: 2004
    ..3. Quantify and demonstrate improved reproducibility of the volumetric flow rates and the resulting ICP values. ..
  2. Development and Early Clinical Evaluation of Noninvasive MRI Measurement of ICP
    Noam Alperin; Fiscal Year: 2006
    ..Preliminary results demonstrated lesser inter-individual variability of the normalized tCBF measurement. ..