David B Allison

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint Two-stage testing in microarray analysis: what is gained?
    David B Allison
    Department of Biostatistics, University of Alabama at Birmingham, USA
    J Gerontol A Biol Sci Med Sci 57:B189-92. 2002
  2. pmc Submitted for your consideration: potential advantages of a novel clinical trial design and initial patient reaction
    Matthew Shane Loop
    Section on Statistical Genetics, Department of Biostatistics, Ryals School of Public Health, University of Alabama at Birmingham Birmingham, AL, USA
    Front Genet 3:145. 2012
  3. pmc Sexual dimorphism of adipose tissue distribution across the lifespan: a cross-sectional whole-body magnetic resonance imaging study
    Wei Shen
    Obesity Research Center, St, Luke s Roosevelt Hospital and Institute of Human Nutrition, Columbia University, College of Physicians and Surgeons, New York, NY, USA
    Nutr Metab (Lond) 6:17. 2009
  4. ncbi request reprint Understanding the relationship between baseline BMI and subsequent weight change in antipsychotic trials: effect modification or regression to the mean?
    David B Allison
    Department of Biostatistics, University of Alabama, Birmingham, AL, USA
    Psychiatry Res 170:172-6. 2009
  5. pmc Bias in estimates of quantitative-trait-locus effect in genome scans: demonstration of the phenomenon and a method-of-moments procedure for reducing bias
    David B Allison
    Department of Biostatistics and Center for Research on Clinical Nutrition, University of Alabama at Birmingham, 35294 0022, USA
    Am J Hum Genet 70:575-85. 2002
  6. pmc Pharmacogenetic association of the APOA1/C3/A4/A5 gene cluster and lipid responses to fenofibrate: the genetics of lipid-lowering drugs and diet network study
    Yongjun Liu
    Departments of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Pharmacogenet Genomics 19:161-9. 2009
  7. pmc The PowerAtlas: a power and sample size atlas for microarray experimental design and research
    Grier P Page
    Department of Biostatistics, University of Alabama, Birmingham, AL, USA
    BMC Bioinformatics 7:84. 2006
  8. ncbi request reprint Epistatic interaction between two nonstructural loci on chromosomes 7 and 3 influences hepatic lipase activity in BSB mice
    Nengjun Yi
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama, Birmingham, AL 35294, USA
    J Lipid Res 45:2063-70. 2004
  9. pmc A proposed metric for assessing the measurement quality of individual microarrays
    Kyoungmi Kim
    Department of Biostatistics, University of Alabama, Birmingham, Alabama, USA
    BMC Bioinformatics 7:35. 2006
  10. ncbi request reprint Detection of gene x gene interactions in genome-wide association studies of human population data
    Solomon K Musani
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Hum Hered 63:67-84. 2007

Detail Information

Publications115 found, 100 shown here

  1. ncbi request reprint Two-stage testing in microarray analysis: what is gained?
    David B Allison
    Department of Biostatistics, University of Alabama at Birmingham, USA
    J Gerontol A Biol Sci Med Sci 57:B189-92. 2002
    ..Therefore, investigators are encouraged to consider alternative analytic approaches...
  2. pmc Submitted for your consideration: potential advantages of a novel clinical trial design and initial patient reaction
    Matthew Shane Loop
    Section on Statistical Genetics, Department of Biostatistics, Ryals School of Public Health, University of Alabama at Birmingham Birmingham, AL, USA
    Front Genet 3:145. 2012
    ..Research is needed as to how the RRD will work in practice and its relative statistical properties, and we invite dialog about it...
  3. pmc Sexual dimorphism of adipose tissue distribution across the lifespan: a cross-sectional whole-body magnetic resonance imaging study
    Wei Shen
    Obesity Research Center, St, Luke s Roosevelt Hospital and Institute of Human Nutrition, Columbia University, College of Physicians and Surgeons, New York, NY, USA
    Nutr Metab (Lond) 6:17. 2009
    ..abstract:..
  4. ncbi request reprint Understanding the relationship between baseline BMI and subsequent weight change in antipsychotic trials: effect modification or regression to the mean?
    David B Allison
    Department of Biostatistics, University of Alabama, Birmingham, AL, USA
    Psychiatry Res 170:172-6. 2009
    ..This class of drugs appears to cause similar weight gain in both high and low baseline BMI groups...
  5. pmc Bias in estimates of quantitative-trait-locus effect in genome scans: demonstration of the phenomenon and a method-of-moments procedure for reducing bias
    David B Allison
    Department of Biostatistics and Center for Research on Clinical Nutrition, University of Alabama at Birmingham, 35294 0022, USA
    Am J Hum Genet 70:575-85. 2002
    ..Finally, limitations of the MOM approach are noted, and we discuss some alternative procedures that may also reduce bias...
  6. pmc Pharmacogenetic association of the APOA1/C3/A4/A5 gene cluster and lipid responses to fenofibrate: the genetics of lipid-lowering drugs and diet network study
    Yongjun Liu
    Departments of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Pharmacogenet Genomics 19:161-9. 2009
    ..The apolipoproteins (APOA1/C3/A4/A5) are key components in modulating lipoprotein metabolism. It is unknown whether variants at the APOA1/C3/A4/A5 gene cluster are associated with lipid response to pharmacologic intervention...
  7. pmc The PowerAtlas: a power and sample size atlas for microarray experimental design and research
    Grier P Page
    Department of Biostatistics, University of Alabama, Birmingham, AL, USA
    BMC Bioinformatics 7:84. 2006
    ..In addition, investigators frequently do not have pilot data to estimate the sample sizes required for microarray studies...
  8. ncbi request reprint Epistatic interaction between two nonstructural loci on chromosomes 7 and 3 influences hepatic lipase activity in BSB mice
    Nengjun Yi
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama, Birmingham, AL 35294, USA
    J Lipid Res 45:2063-70. 2004
    ..SPRET/Pt alleles of the QTL on each chromosome promote hepatic lipase activity. The proportion of phenotypic variance explained by the epistatic effect is higher than that explained by the main effect of the QTL on chromosome 7...
  9. pmc A proposed metric for assessing the measurement quality of individual microarrays
    Kyoungmi Kim
    Department of Biostatistics, University of Alabama, Birmingham, Alabama, USA
    BMC Bioinformatics 7:35. 2006
    ..In some cases this may be manifested as systematic spatial variation on the surface of microarray in which expression measurements within an individual array may vary as a function of geographic position on the array surface...
  10. ncbi request reprint Detection of gene x gene interactions in genome-wide association studies of human population data
    Solomon K Musani
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Hum Hered 63:67-84. 2007
    ..Instead, a combination of approaches with the aim of balancing their specific strengths may be the optimal approach to investigate gene x gene interactions in human data...
  11. pmc Rank-based inverse normal transformations are increasingly used, but are they merited?
    T Mark Beasley
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Ryals Public Health Building, Suite 327, Birmingham, AL, 35294, USA
    Behav Genet 39:580-95. 2009
    ..Rigorous research evaluating the utility of INTs seems warranted...
  12. ncbi request reprint No evidence for a major role of polymorphisms during bupropion treatment
    Jianfang Hu
    Department of Biostatistics, Section on Statistical Genetics, Ryals Public Health Building, Suite 327, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL 35294, USA
    Obesity (Silver Spring) 14:1863-7. 2006
    ..Overall, our results do not support a major role for these five candidate genes in weight gain after smoking cessation...
  13. ncbi request reprint New joint covariance- and marginal-based tests for association and linkage for quantitative traits for random and non-random sampling
    Hemant K Tiwari
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Genet Epidemiol 28:48-57. 2005
    ..Both random sampling and extreme sampling schemes were investigated. A multinomial logistic joint test provides the highest overall power irrespective of sample size, allele frequency, heritability, and modes of inheritance...
  14. pmc Characterization of epistasis influencing complex spontaneous obesity in the BSB model
    Nengjun Yi
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama, Birmingham, Alabama 35294, USA
    Genetics 167:399-409. 2004
    ..Chromosomes 6 and 12 have not only main effects but also strong epistatic effects on plasma total cholesterol. Our results emphasize the importance of modeling epistasis for discovery of obesity genes...
  15. pmc Endocrine disruptors and obesity: an examination of selected persistent organic pollutants in the NHANES 1999-2002 data
    Mai A Elobeid
    Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Int J Environ Res Public Health 7:2988-3005. 2010
    ..Hence, BMI and WC are associated with POPs levels, making the chemicals plausible contributors to the obesity epidemic...
  16. ncbi request reprint Mapping multiple quantitative trait Loci for ordinal traits
    Nengjun Yi
    Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
    Behav Genet 34:3-15. 2004
    ..To this end, we provide a unified approach to mapping multiple QTL for continuous, binary, and ordinal traits. Utility and flexibility of the method are demonstrated using simulated data...
  17. pmc The effect of mannan oligosaccharide supplementation on body weight gain and fat accrual in C57Bl/6J mice
    Daniel L Smith
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA
    Obesity (Silver Spring) 18:995-9. 2010
    ..247 g; P = 0.57). Contrary to previous research, MOS supplementation had no discernable effect on body weight gain or composition during this 12-week study, challenging the potential use of MOS as a CRM or body composition enhancer...
  18. ncbi request reprint Bayesian analyses of multiple epistatic QTL models for body weight and body composition in mice
    Nengjun Yi
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama, Birmingham, AL 35294, USA
    Genet Res 87:45-60. 2006
    ..Several main and epistatic effects were shared by the body composition and body weight traits, suggesting that pleiotropy plays an important role in growth and obesity...
  19. pmc Regional admixture mapping and structured association testing: conceptual unification and an extensible general linear model
    David T Redden
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS Genet 2:e137. 2006
    ....
  20. ncbi request reprint Principal component analysis of quantitative trait loci for immune response to adenovirus in mice
    Solomon K Musani
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, AL 35294 0007, USA
    Hereditas 143:189-97. 2006
    ..01 and 31.01 cM) and 15 (29.21, 36.01, and 56.31 cM). These results illustrate the use of principal component analysis in mapping QTLs using multiple correlated traits...
  21. pmc Effects of risperidone on energy balance in female C57BL/6J mice
    Xingsheng Li
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama
    Obesity (Silver Spring) 21:1850-7. 2013
    ..To investigate the effect of risperidone on energy expenditure and weight gain in female C57BL/6J mice...
  22. doi request reprint Randomized controlled trial of chewing gum for weight loss
    James M Shikany
    Division of Preventive Medicine, Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Obesity (Silver Spring) 20:547-52. 2012
    ..Analyses including completers only produced essentially the same results. We conclude that chewing gum on a regular schedule for 8 weeks did not facilitate weight loss in these overweight and obese adults...
  23. doi request reprint Does obesity associate with mortality among Hispanic persons? Results from the National Health Interview Survey
    Tapan Mehta
    Department of Biostatistics, Section on Statistical Genetics and Nutrition Obesity Research Center, University of Alabama at Birmingham, AL, USA
    Obesity (Silver Spring) 21:1474-7. 2013
    ..To evaluate the association between BMI: kg/m(2) and mortality among Hispanic adults...
  24. pmc A comprehensive genetic approach for improving prediction of skin cancer risk in humans
    Ana I Vazquez
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama, Birmingham, AL 35294, USA
    Genetics 192:1493-502. 2012
    ..We discuss avenues for improving prediction accuracy and speculate on the possible use of WGP to prospectively identify individuals at high risk...
  25. pmc HDBStat!: a platform-independent software suite for statistical analysis of high dimensional biology data
    Prinal Trivedi
    Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    BMC Bioinformatics 6:86. 2005
    ..HDBStat! provides statisticians and biologists a flexible and easy-to-use interface to analyze complex microarray data using a variety of methods for data preprocessing, quality control analysis and hypothesis testing...
  26. ncbi request reprint Optimal allocation of replicates for measurement evaluation studies
    Stanislav O Zakharkin
    Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    Genomics Proteomics Bioinformatics 4:196-202. 2006
    ..Therefore, it is recommended to use two technical replicates for each biological replicate if the goal is to evaluate the reproducibility of measurements...
  27. pmc Joint tests for quantitative trait loci in experimental crosses
    T Mark Beasley
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, AL, USA
    Genet Sel Evol 36:601-19. 2004
    ..Joint tests were generally more powerful for one-tailed selection under both backcross and F2 intercross situations. However, joint tests cannot be recommended for one-tailed selective genotyping if segregation distortion is suspected...
  28. pmc Intramyocellular lipid and insulin resistance: differential relationships in European and African Americans
    Katherine H Ingram
    Department of Biostatistics, University of Alabama, Birmingham, Alabama, USA
    Obesity (Silver Spring) 19:1469-75. 2011
    ..These results highlight ethnic differences in the determinants of insulin sensitivity and in the pathogenesis of the metabolic syndrome trait cluster...
  29. pmc Ancestry-informative markers on chromosomes 2, 8 and 15 are associated with insulin-related traits in a racially diverse sample of children
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA
    Hum Genomics 5:79-89. 2011
    ..Importantly, we have implicated this region in the early development of diabetes-related phenotypes, and in the genetic aetiology of population differences in these phenotypes...
  30. ncbi request reprint The effects of intentional weight loss as a latent variable problem
    Christopher S Coffey
    Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Stat Med 24:941-54. 2005
    ....
  31. pmc Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP)
    David B Allison
    Department of Biostatistics, School of Public Health and Nutrition Obesity Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Obesity (Silver Spring) 20:330-42. 2012
    ..75/23 patients, and 33.6% of 15/92 patients. PHEN/TPM CR demonstrated dose-dependent effects on weight and metabolic variables in the direction expected to be beneficial with no evidence of serious adverse events induced by treatment...
  32. pmc Natural selection at genomic regions associated with obesity and type-2 diabetes: East Asians and sub-Saharan Africans exhibit high levels of differentiation at type-2 diabetes regions
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, 1665 University Blvd, RPHB 327, Birmingham, AL 35294, USA
    Hum Genet 129:407-18. 2011
    ..Our findings suggest that there is an evolutionary genetic basis for population differences in these traits, and we have identified potential group-specific genetic risk factors...
  33. ncbi request reprint Is dietary fat "fattening"? A comprehensive research synthesis
    James M Shikany
    Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, MT610 Birmingham, AL 35294, USA
    Crit Rev Food Sci Nutr 50:699-715. 2010
    ..General recommendations to reduce dietary fat to promote weight loss or maintenance in all circumstances may merit reconsideration...
  34. pmc Fruit and vegetable pricing by demographic factors in the Birmingham, Alabama, metropolitan area, 2004-2005
    Jamy D Ard
    University of Alabama at Birmingham, 1675 University Blvd, Webb 441, Birmingham, AL 35294, USA
    Prev Chronic Dis 7:A78. 2010
    ..Because the contextual environment influences food outlet type and availability, we wanted to determine whether neighborhood demographics were associated with prices of fruits and vegetables...
  35. ncbi request reprint Microarray data analysis: from disarray to consolidation and consensus
    David B Allison
    Section on Statistical Genetics, Department of Biostatistics, Ryals Public Health Building, 1665 University Avenue, University of Alabama at Birmingham, Alabama 35294 0022, USA
    Nat Rev Genet 7:55-65. 2006
    ..Many are special cases of more general models, and points of consensus are emerging about the general approaches that warrant use and elaboration...
  36. pmc An African ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in African Americans
    James M Kelley
    University of Alabama at Birmingham, Birmingham, AL, USA
    PLoS Genet 5:e1000424. 2009
    ..An African ancestry-specific genetic variant of CTLA4 appears to be associated with protection from RA in African Americans. This finding may explain, in part, the relatively low prevalence of RA in black African populations...
  37. pmc Prediction of expected years of life using whole-genome markers
    Gustavo de Los Campos
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 7:e40964. 2012
    ....
  38. pmc BMI and headache among women: results from 11 epidemiologic datasets
    Scott W Keith
    Section on Statistical Genetics and Clinical Nutrition Research Center, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA
    Obesity (Silver Spring) 16:377-83. 2008
    ..To evaluate the association between BMI (kg/m(2)) and headaches among women...
  39. pmc Haplotyping methods for pedigrees
    Guimin Gao
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, Ala, USA
    Hum Hered 67:248-66. 2009
    ..We explore the connections among these methods, and describe the challenges that remain to be addressed...
  40. pmc Missing data in randomized clinical trials for weight loss: scope of the problem, state of the field, and performance of statistical methods
    Mai A Elobeid
    Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 4:e6624. 2009
    ..Herein, we meta-analytically evaluate the extent of missing data, the frequency with which various analytic methods are employed to accommodate dropouts, and the performance of multiple statistical methods...
  41. pmc Genes and biochemical pathways in human skeletal muscle affecting resting energy expenditure and fuel partitioning
    Xuxia Wu
    Dept of Nutrition Sciences, The Univ of Alabama at Birmingham, 1675 University Blvd, Birmingham, AL 35294 3360, USA
    J Appl Physiol (1985) 110:746-55. 2011
    ..Individual variations in whole body REE and RQ are regulated by differential expressions of specific genes and pathways intrinsic to skeletal muscle...
  42. pmc Sample size in obesity trials: patient perspective versus current practice
    David B Allison
    Department of Nutrition Sciences and the Clinical Nutrition Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Med Decis Making 30:68-75. 2010
    ..To evaluate patient opinions on acceptable risks in exchange for a given degree of weight loss and their implications for sample size determination in obesity randomized clinical trials (RCTs)...
  43. pmc Bayesian model selection for genome-wide epistatic quantitative trait loci analysis
    Nengjun Yi
    Department of Biostatistics, University of Alabama, Birmingham 35294, USA
    Genetics 170:1333-44. 2005
    ..We illustrate the proposed method by detecting new epistatic QTL for obesity in a backcross of CAST/Ei mice onto M16i...
  44. pmc Sources of variation in Affymetrix microarray experiments
    Stanislav O Zakharkin
    University of Alabama, Birmingham, Alabama, USA
    BMC Bioinformatics 6:214. 2005
    ..The objectives of this study were: (1) to estimate relative magnitudes of different sources of variation and (2) to evaluate agreement between biological and technical replicates...
  45. doi request reprint Obesity among those with mental disorders: a National Institute of Mental Health meeting report
    David B Allison
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Am J Prev Med 36:341-50. 2009
    ....
  46. ncbi request reprint Intramyocellular lipid content is lower with a low-fat diet than with high-fat diets, but that may not be relevant for health
    Marie Pierre St-Onge
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Clin Nutr 86:1316-22. 2007
    ..Fat deposition in muscle has been found to be related to metabolic risk...
  47. pmc Turning the analysis of obesity-mortality associations upside down: modeling years of life lost through conditional distributions
    Henry T Robertson
    Biostatistics Department, University of Alabama at Birmingham, Birmingham, USA
    Obesity (Silver Spring) 21:398-404. 2013
    ....
  48. pmc Myths, presumptions, and facts about obesity
    Krista Casazza
    Department of Nutrition Sciences, of Alabama at Birmingham, Birmingham, USA
    N Engl J Med 368:446-54. 2013
    ....
  49. pmc Calorie restriction: what recent results suggest for the future of ageing research
    Daniel L Smith
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Eur J Clin Invest 40:440-50. 2010
    ..Thus, the search for substances that can reproduce the beneficial physiologic responses of CR without a requisite calorie intake reduction, termed CR mimetics (CRMs), has gained momentum...
  50. ncbi request reprint The effect of assortative mating upon genetic association studies: spurious associations and population substructure in the absence of admixture
    David T Redden
    Department of Biostatistics, Section on Statistical Genetics and Clinical Nutrition Research Center, University of Alabama at Birmingham, Birmingham, USA
    Behav Genet 36:678-86. 2006
    ....
  51. pmc Weighted multiple hypothesis testing procedures
    Guolian Kang
    University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Stat Appl Genet Mol Biol 8:Article23. 2009
    ..All proposed procedures control the FWER well and are useful when prior information is available to estimate the weights...
  52. pmc Review and evaluation of methods correcting for population stratification with a focus on underlying statistical principles
    Hemant K Tiwari
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Hum Hered 66:67-86. 2008
    ....
  53. pmc Telomere dynamics in rhesus monkeys: no apparent effect of caloric restriction
    Daniel L Smith
    University of Alabama at Birmingham, Main Campus, Birmingham, AL 35294 3360, USA
    J Gerontol A Biol Sci Med Sci 66:1163-8. 2011
    ..002) and sex (p = .003; p = .042), but not calorie restriction (p = .884; p = .766). Despite an age-dependent shortening of TL in leukocytes and skin, calorie restriction did not significantly affect TL dynamics in these samples...
  54. pmc Bayesian model choice and search strategies for mapping interacting quantitative trait Loci
    Nengjun Yi
    Department of Biostatistics, University of Alabama, Birmingham, Alabama 35294, USA
    Genetics 165:867-83. 2003
    ..Utility and flexibility of the method are demonstrated using both simulated data and a real data set. Sensitivity of posterior inference to prior specifications of the number and genetic effects of QTL is investigated...
  55. pmc Propagation of obesity across generations: the roles of differential realized fertility and assortative mating by body mass index
    John A Dawson
    Office of Energetics, School of Public Health, University of Alabama at Birmingham, Birmingham, Ala, USA
    Hum Hered 75:204-12. 2013
    ....
  56. pmc Portion sizes for children are predicted by parental characteristics and the amounts parents serve themselves
    Susan L Johnson
    Department of Pediatrics, Section of Nutrition, University of Colorado Anschutz Medical Campus, Aurora, Colorado SLJ the Children s Nutrition Research Center, Baylor College of Medicine, Houston, TX SOH, TN, yl, and KV the Office of Energetics, Nutrition Obesity Research Center, and Section on Statistical Genetics, Department of Biostatistics, University of Alabama Birmingham, Birmingham, AL DBA, xc, and XL the Department of Human Development, Washington State University, Pullman, Washington TGP and the Departments of Food, Bioprocessing, and Nutrition Sciences, North Carolina State University, Raleigh, NC LSG
    Am J Clin Nutr 99:763-70. 2014
    ..Children's energy intakes are influenced by the portions they are served. Factors influencing the amounts adults offer children are not well described...
  57. pmc Conjectures on some curious connections among social status, calorie restriction, hunger, fatness, and longevity
    Kathryn A Kaiser
    Office of Energetics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Ann N Y Acad Sci 1264:1-12. 2012
    ..Second, we examine models of the interactions between caloric restriction, body composition, and longevity. Finally, we put forth a relational model of the influences of differing environmental cues on body composition and longevity...
  58. pmc A generalized sequential Bonferroni procedure using smoothed weights for genome-wide association studies incorporating information on Hardy-Weinberg disequilibrium among cases
    Guimin Gao
    Department of Biostatistics, Virginia Commonwealth University, Richmond, VA 23298 0032, USA
    Hum Hered 73:1-13. 2012
    ....
  59. pmc Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study
    W Timothy Garvey
    Department of Nutrition Sciences, UAB Diabetes Research and Training Center, University of Alabama at Birmingham, 35294 3360, USA
    Am J Clin Nutr 95:297-308. 2012
    ....
  60. ncbi request reprint Obesity: person and population
    Mark B Cope
    Department of Nutrition Sciences, University of Alabama at Birmingham, Ryals Public Health Building 327, 1665 University Boulevard, Birmingham, AL 35294, USA
    Obesity (Silver Spring) 14:156S-159S. 2006
    ..If we are to make pervasive and enduring changes to population adiposity levels, it is likely that we will need to make pervasive and enduring changes to the ways in which we live across the lifespan...
  61. ncbi request reprint Comparison of linear weighting schemes for perfect match and mismatch gene expression levels from microarray data
    T Mark Beasley
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Am J Pharmacogenomics 5:197-205. 2005
    ....
  62. pmc Testing for differences in distribution tails to test for differences in 'maximum' lifespan
    Guimin Gao
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, Alabama, USA
    BMC Med Res Methodol 8:49. 2008
    ..However, a limitation of these tests is that they do not consider how much above the threshold any particular observation is...
  63. ncbi request reprint Catechol-O-methyl-transferase functional polymorphism and nicotine dependence: an evaluation of nonreplicated results
    David T Redden
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Alabama 35294 0022, USA
    Cancer Epidemiol Biomarkers Prev 14:1384-9. 2005
    ....
  64. pmc Beyond missing heritability: prediction of complex traits
    Robert Makowsky
    Department of Biostatistics, University of Alabama at Birmingham, Alabama, United States of America
    PLoS Genet 7:e1002051. 2011
    ..While such R(2) values vastly exceed what has been previously reported using a reduced number of pre-selected markers (<0.10), given the heritability of the trait (∼ 0.80), substantial room for improvement remains...
  65. pmc Mapping interacting QTL for count phenotypes using hierarchical Poisson and binomial models: an application to reproductive traits in mice
    Jun Li
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Genet Res (Camb) 92:13-23. 2010
    ..The proposed statistical models and methods provide valuable tools for detecting multiple interacting QTLs for complex count phenotypes...
  66. ncbi request reprint Effects of a reimbursement incentive on enrollment in a weight control program
    W Scott Butsch
    Department of Nutrition Sciences, University of Alabama at Birmingham, Webb 439, 1675 University Blvd, Birmingham, AL 35294 3360, USA
    Obesity (Silver Spring) 15:2733-8. 2007
    ..The objective was to examine the effect of offering a reimbursement incentive on the percentage of inquirers who enrolled in a weight control program and on weight loss and program attendance among enrollees...
  67. ncbi request reprint Applications of Bayesian statistical methods in microarray data analysis
    Dongyan Yang
    Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Am J Pharmacogenomics 4:53-62. 2004
    ..Bayesian methods will undoubtedly become more common in the future because of their great utility in microarray analysis...
  68. ncbi request reprint Effect of dairy supplementation on body composition and insulin resistance in mice
    Maria S Johnson
    Department of Nutrition Sciences, University of Alabama at Birmingham, Alabama, USA
    Nutrition 23:836-43. 2007
    ..This study examined whether yogurt supplementation attenuated the weight gain and insulin resistance in mice fed a moderate-fat diet...
  69. ncbi request reprint A simple significance test for quantile regression
    David T Redden
    Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
    Stat Med 23:2587-97. 2004
    ....
  70. pmc Frequent genetic differences between matched primary and metastatic breast cancer provide an approach to identification of biomarkers for disease progression
    Andrzej B Popławski
    Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA
    Eur J Hum Genet 18:560-8. 2010
    ..Frequent genetic differences between primary tumors and metastases in breast cancer also question, at least to some extent, the role of primary tumors as a surrogate subject of study for the systemic disease...
  71. pmc Can rodent longevity studies be both short and powerful?
    Henry T Robertson
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    J Gerontol A Biol Sci Med Sci 66:279-86. 2011
    ..4 times as many rodents will often have equivalent or greater power. Cost calculations suggest that shorter studies will be more expensive but perhaps not so much to not be worth the reduced time...
  72. ncbi request reprint Epistemological issues in omics and high-dimensional biology: give the people what they want
    Tapan S Mehta
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Physiol Genomics 28:24-32. 2006
    ..The shift from family-wise error rate control to false discovery rate estimation and to assessment of ranking and other forms of stability will be portrayed as illustrative of approaches to this challenge...
  73. ncbi request reprint Mapping quantitative trait loci affecting variation in Drosophila triacylglycerol storage
    Maria De Luca
    Department of Environmental Health Sciences, University of Alabama, Birmingham, AL 35294, USA
    Obes Res 13:1596-605. 2005
    ..The objective of our study was to identify quantitative trait loci (QTLs) that contribute to variation in triacylglycerol (TAG) storage in two D. melanogaster laboratory strains...
  74. pmc Marker genotypes and population admixture and their association with body weight, height and relative body mass in United States federal bison herds
    Solomon K Musani
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama, Alabama 35294, USA
    Genetics 174:775-83. 2006
    ..Individual loci contributed approximately 2.0% of variation in weight, height, and BMI, which confirms the utility and potential importance of adjusting for population stratification...
  75. pmc Snack chips fried in corn oil alleviate cardiovascular disease risk factors when substituted for low-fat or high-fat snacks
    Marie Pierre St-Onge
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Clin Nutr 85:1503-10. 2007
    ..The perception that all high-fat snacks are unhealthy may be wrong...
  76. pmc Metformin supplementation and life span in Fischer-344 rats
    Daniel L Smith
    Department of Biostatistics, Ryals Public Health Building, Suite 414, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL, USA
    J Gerontol A Biol Sci Med Sci 65:468-74. 2010
    ..05) compared with control...
  77. pmc An empirical Bayes method for updating inferences in analysis of quantitative trait loci using information from related genome scans
    Kui Zhang
    Department of Biostatistics, Section of Statistical Genetics, University of Alabama, Birmingham 35294, USA
    Genetics 173:2283-96. 2006
    ..In the face of marked heterogeneity among studies, the empirical Bayes method outperforms the comparator...
  78. pmc Natural selection among Eurasians at genomic regions associated with HIV-1 control
    Yann C Klimentidis
    Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    BMC Evol Biol 11:173. 2011
    ....
  79. ncbi request reprint A design and statistical perspective on microarray gene expression studies in nutrition: the need for playful creativity and scientific hard-mindedness
    Grier P Page
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
    Nutrition 19:997-1000. 2003
    ....
  80. ncbi request reprint Nonreplication in genetic association studies of obesity and diabetes research
    David T Redden
    Department of Biostatistics, Section on Statistical Genetics and Clinical Nutrition Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Nutr 133:3323-6. 2003
    ..Recommendations to improve future association studies are presented...
  81. ncbi request reprint Improving the power of sib pair quantitative trait loci detection by phenotype winsorization
    Jose R Fernandez
    Department of Nutrition Sciences, Division of Physiology and Metabolism, The University of Alabama at Birmingham, 35294 3360, USA
    Hum Hered 53:59-67. 2002
    ..We evaluated the robustness and power of reducing the influence of subjects with extreme phenotypic values by Winsorizing non-normal distributions in three versions of Haseman-Elston regression-based methods of QTL linkage analysis...
  82. ncbi request reprint Beneficial influences of systemic cooperation and sociological behavior on longevity
    John D Mountz
    Division of Clinical Immunology and Rheumatology, Department of Medicine, The University of Alabama at Birmingham, 701 South 19th Street, LHRB 473, Birmingham, AL 35294 0007, USA
    Mech Ageing Dev 123:963-73. 2002
    ....
  83. ncbi request reprint Is percentage body fat differentially related to body mass index in Hispanic Americans, African Americans, and European Americans?
    Jose R Fernandez
    Obesity Research Center, St Luke s Roosevelt Hospital and the Institute of Human Nutrition, Columbia University College of Physicians and Surgeons, New York, USA
    Am J Clin Nutr 77:71-5. 2003
    ....
  84. pmc Stochastic search variable selection for identifying multiple quantitative trait loci
    Nengjun Yi
    Department of Biostatistics, University of Alabama, Birmingham 35294 0022, USA
    Genetics 164:1129-38. 2003
    ..The results demonstrate that the proposed method works well under typical situations of most QTL studies in terms of number of markers and marker density...
  85. pmc Attitudes and beliefs associated with leisure-time physical activity among African American adults
    Olivia Affuso
    Department of Epidemiology, University of Alabama at Birmingham 35294 0013, USA
    Ethn Dis 21:63-7. 2011
    ..We sought to discover the extent to which health attitudes and beliefs are associated with leisure-time physical activity in this population...
  86. ncbi request reprint The impact of weight gain on quality of life among persons with schizophrenia
    David B Allison
    Department of Biostatistics, Section on Statistical Genetics and Clinical Nutrition Research Center, Suite 327 Ryals Public Health Building, University of Alabama at Birmingham, 1665 University Avenue, Birmingham, AL 35294, USA
    Psychiatr Serv 54:565-7. 2003
    ..Clinicians should consider the effect of weight gain on quality of life when prescribing antipsychotics and should help patients adopt weight maintenance behaviors...
  87. ncbi request reprint Association of African genetic admixture with resting metabolic rate and obesity among women
    Jose R Fernandez
    Department of Nutrition Sciences and the Clinical Nutrition Research Center, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Obes Res 11:904-11. 2003
    ....
  88. ncbi request reprint Predicting genetic predisposition in humans: the promise of whole-genome markers
    Gustavo de Los Campos
    University of Alabama at Birmingham, 35294, USA
    Nat Rev Genet 11:880-6. 2010
    ..We propose that alternative approaches, which are largely borrowed from animal breeding, provide potential for advances. We review selected methods and discuss the challenges and opportunities ahead...
  89. doi request reprint Obesity as a disease: a white paper on evidence and arguments commissioned by the Council of the Obesity Society
    David B Allison
    Department of Biostatistics and Clinical Nutrition Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Obesity (Silver Spring) 16:1161-77. 2008
  90. ncbi request reprint Dietary restraint and disinhibition do not affect accuracy of 24-hour recall in a multiethnic population
    Jamy D Ard
    Nutrition Sciences and Medicine, Department of Medicine, University of Alabama, Birmingham, USA
    J Am Diet Assoc 106:434-7. 2006
    ..Disinhibition was not related to intake or accuracy. Dietetics professionals should consider dietary restraint a possible reason for a lower than expected estimate of energy intake when using 24-hour recalls...
  91. ncbi request reprint Waist circumference percentiles in nationally representative samples of African-American, European-American, and Mexican-American children and adolescents
    Jose R Fernandez
    Section on Statistical Genetics, Department of Biostatistics, Clinical Nutrition Research Center, University of Alabama at Birmingham, 35294 3360, USA
    J Pediatr 145:439-44. 2004
    ..To describe and provide estimates of the distribution of waist circumference (WC) according to percentiles in African-, European-, and Mexican-American children, and to test for group differences at different percentiles...
  92. ncbi request reprint Treatment and prevention of obesity: what works, what doesn't work, and what might work
    David B Allison
    Department of Biostatistics, Section on Statistical Genetics and Clinical Nutrition Research Center, University of Alabama at Birmingham, Alabama 35294 0022, USA
    Lipids 38:147-55. 2003
    ..Perhaps, with continued efforts at enhancing treatments, we will see incremental advances in the treatment and prevention of obesity...
  93. pmc Divergence in popular diets relative to diets consumed by Americans, and implications for diet selection
    James M Shikany
    Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, USA
    MedGenMed 9:8. 2007
    ..We hypothesized that because most of these diets differ greatly from the way most Americans spontaneously eat, the choice of a WLD may be less critical than the decision to adopt any WLD...
  94. ncbi request reprint Is GAD2 on chromosome 10p12 a potential candidate gene for morbid obesity?
    Hemant K Tiwari
    Department of Biostatistics, Section on Statistical Genetics, University of Alabama, Birmingham 35294, USA
    Nutr Rev 63:315-9. 2005
    ..Also discussed are additional research questions that merit inquiry when further evaluating this genetic variant as a putative contributor to human obesity...
  95. pmc The impact of cost on the availability of fruits and vegetables in the homes of schoolchildren in Birmingham, Alabama
    Jamy D Ard
    Department of Nutrition Sciences, University of Alabama, Birmingham, USA
    Am J Public Health 97:367-72. 2007
    ..We sought to determine whether fruit and vegetable cost and consumers' race and income would predict availability of fruits and vegetables in homes of schoolchildren in the Birmingham, Ala, area...
  96. pmc Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles
    Carl E G Bruder
    Department of Genetics, University of Alabama at Birmingham, Birmingham, AL 35294 0024, USA
    Am J Hum Genet 82:763-71. 2008
    ..Our results also imply that caution should be exercised when interpreting disease causality of de novo CNVs found in patients based on analysis of a single tissue in routine disease-related DNA diagnostics...
  97. pmc Use of causal language in observational studies of obesity and nutrition
    Stacey S Cofield
    Department of Biostatistics, University of Alabama, Birmingham, AL, USA
    Obes Facts 3:353-6. 2010
    ..To assess the inappropriate use of causal language in studies on obesity and nutrition...
  98. ncbi request reprint Project Grow-2-Gether: a study of the genetic and environmental influences on child eating and obesity
    Myles S Faith
    Weight and Eating Disorders Program, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Twin Res 5:472-5. 2002
    ..Future directions may involve longitudinal assessment of child growth and molecular analyses for specific genes that influence child eating behavior...
  99. ncbi request reprint Changes in body mass index for individuals with and without schizophrenia, 1987-1996
    Peter Homel
    Office of Research Support, Beth Israel Medical Center, New York, NY, USA
    Schizophr Res 55:277-84. 2002
    ..The mechanism that underlies this weight age and sex specific time trend is unclear...
  100. ncbi request reprint Obesity--still highly heritable after all these years
    Solomon K Musani
    Am J Clin Nutr 87:275-6. 2008