Thaddeus D Allen

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Interaction between MYC and MCL1 in the genesis and outcome of non-small-cell lung cancer
    Thaddeus D Allen
    G W Hooper Research Foundation, University of California, San Francisco, USA
    Cancer Res 71:2212-21. 2011
  2. pmc Activated Notch1 induces lung adenomas in mice and cooperates with Myc in the generation of lung adenocarcinoma
    Thaddeus D Allen
    G W Hooper Research Foundation, University of California, San Francisco, San Francisco, California 94143 0552, USA
    Cancer Res 71:6010-8. 2011
  3. pmc The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type
    Mariia O Yuneva
    G W Hooper Research Foundation, University of California, San Francisco, San Francisco, CA 94143, USA
    Cell Metab 15:157-70. 2012

Collaborators

Detail Information

Publications3

  1. pmc Interaction between MYC and MCL1 in the genesis and outcome of non-small-cell lung cancer
    Thaddeus D Allen
    G W Hooper Research Foundation, University of California, San Francisco, USA
    Cancer Res 71:2212-21. 2011
    ..Our findings therefore produce a convergence of mouse and human results that explain how MCL1 can block an important negative consequence of MYC overexpression in both experimental models and clinical cases of NSCLC...
  2. pmc Activated Notch1 induces lung adenomas in mice and cooperates with Myc in the generation of lung adenocarcinoma
    Thaddeus D Allen
    G W Hooper Research Foundation, University of California, San Francisco, San Francisco, California 94143 0552, USA
    Cancer Res 71:6010-8. 2011
    ..These tumor models should be valuable for exploring the role of activated Notch1 in the genesis of NSCLC and for testing therapies targeting either activated Notch1 or its downstream effectors...
  3. pmc The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type
    Mariia O Yuneva
    G W Hooper Research Foundation, University of California, San Francisco, San Francisco, CA 94143, USA
    Cell Metab 15:157-70. 2012
    ..Our results suggest that the metabolic profiles of tumors are likely to depend on both the genotype and tissue of origin and have implications regarding the design of therapies targeting tumor metabolism...