Research Topics
| Larry A AllenSummaryAffiliation: University of Colorado Denver Country: USA Publications
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Detail Information
Publications
The inpatient experience and predictors of length of stay for patients hospitalized with systolic heart failure: comparison by commercial, Medicaid, and Medicare payer typeLarry A Allen
Section of Advanced Heart Failure and Transplantation, University of Colorado Anschutz Medical Campus, Aurora, USA
J Med Econ 16:43-54. 2013..While length of stay (LOS) is a primary determinant of resource use and post-discharge events, few models exist for estimating LOS...
End points for comparative effectiveness research in heart failureLarry A Allen
Division of Cardiology, University of Colorado School of Medicine, Anschutz Medical Center, Aurora, CO 80045, USA
Heart Fail Clin 9:15-28. 2013..This strategy almost certainly requires increased reliance on prospective studies with proactive end-point capture, preferably in the setting of randomized allocation of the interventions being compared...
Patterns of beta-blocker intensification in ambulatory heart failure patients and short-term association with hospitalizationLarry A Allen
Division of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA
BMC Cardiovasc Disord 12:43. 2012..However, patterns and safety of β-blocker intensification in routine practice are poorly described...
Identifying patients hospitalized with heart failure at risk for unfavorable future quality of lifeLarry A Allen
Colorado Cardiovascular Outcomes Research Group, University of Colorado Denver, Aurora, CO 80045, USA
Circ Cardiovasc Qual Outcomes 4:389-98. 2011..Patients are concerned with both their quantity and quality of life (QoL). To facilitate the recognition of patients at high risk for unfavorable future QoL or death, we created a simple prognostic tool to estimate this combined outcome...
Use of multiple biomarkers in heart failureLarry A Allen
Division of Cardiology, Colorado Cardiovascular Outcomes Research Consortium and Section of Heart Failure and Cardiac Transplantation, University of Colorado Denver, Aurora, CO 80045, USA
Curr Cardiol Rep 12:230-6. 2010..Here we conceptually define multiple biomarker strategies, provide examples of emerging biomarker panels used in the care of patients with heart failure, and address key statistical and clinical issues for this rapidly evolving field...
Discharge to a skilled nursing facility and subsequent clinical outcomes among older patients hospitalized for heart failureLarry A Allen
Colorado Cardiovascular Outcomes Research Consortium, University of Colorado Denver, Aurora, USA
Circ Heart Fail 4:293-300. 2011..Heart failure (HF) is the leading cause of hospitalization among older Americans. Subsequent discharge to skilled nursing facilities (SNF) is not well described...
Relationship between anemia and health care costs in heart failureLarry A Allen
Division of Cardiology, University of Colorado Denver, Aurora, Colorado 80045, USA
J Card Fail 15:843-9. 2009..Anemia is associated with higher morbidity and mortality in patients with heart failure (HF), but its implications for heath care costs are not well described...
End points for clinical trials in acute heart failure syndromesLarry A Allen
Division of Cardiology, Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA
J Am Coll Cardiol 53:2248-58. 2009....
Multi-marker strategies in heart failure: clinical and statistical approachesLarry A Allen
The Division of Cardiology, University of Colorado Denver, Aurora, CO 80045, USA
Heart Fail Rev 15:343-9. 2010..Here, we define multi-marker strategies, summarize recent examples of biomarker combinations in heart failure, address key statistical and clinical issues, and discuss future directions for this rapidly evolving field...
End-point selection for acute heart failure trialsLarry A Allen
Colorado Cardiovascular Outcomes Research Consortium and the Section of Advanced Heart Failure, Division of Cardiology, Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, 12631 East 17th Avenue, Aurora, CO 80045, USA
Heart Fail Clin 7:481-95. 2011....
Continuous versus bolus dosing of Furosemide for patients hospitalized for heart failureLarry A Allen
Colorado Cardiovascular Outcomes Research Group, University of Colorado Denver, Aurora, CO, USA
Am J Cardiol 105:1794-7. 2010..Given the high prevalence of heart failure hospitalization and the disparate results of small studies regarding optimal dosing of loop diuretics to treat these patients, larger multicenter blinded studies are needed...
Implantable cardioverter-defibrillator shocks in patients with a left ventricular assist deviceAmrut V Ambardekar
University of Colorado Denver, Aurora, CO 80045, USA
J Heart Lung Transplant 29:771-6. 2010..However, the rate of implantable cardioverter-defibrillator (ICD) shocks and the effect of these shocks on outcomes in patients with LVADs remain unknown...
Rates and predictors of 30-day readmission among commercially insured and Medicaid-enrolled patients hospitalized with systolic heart failureLarry A Allen
Section of Advanced Heart Failure and Transplantation, University of Colorado School of Medicine, Aurora, CO, USA
Circ Heart Fail 5:672-9. 2012....
Validation and potential mechanisms of red cell distribution width as a prognostic marker in heart failureLarry A Allen
Division of Cardiology, University of Colorado Denver, Aurora, CO, USA
J Card Fail 16:230-8. 2010..Our study sought to validate the prognostic value of RDW in heart failure and to explore the potential mechanisms underlying this association...
Health literacy and outcomes among patients with heart failurePamela N Peterson
Division of Cardiology, Denver Health Medical Center, Mail Code 0960, 777 Bannock St, Denver, CO 80204, USA
JAMA 305:1695-701. 2011..Little is known about the effects of low health literacy among patients with heart failure, a condition that requires self-management and frequent interactions with the health care system...
Management of acute decompensated heart failureLarry A Allen
Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
CMAJ 176:797-805. 2007..Multiple novel therapies are being developed, but previous treatment failures indicate that progress in the management of acute decompensated heart failure is likely to be slow...
Effects of mineralocorticoid receptor antagonists on the risk of sudden cardiac death in patients with left ventricular systolic dysfunction: a meta-analysis of randomized controlled trialsSrinivas R Bapoje
Department of Medicine, Denver Health and Hospital Authority, Denver, CO, USA
Circ Heart Fail 6:166-73. 2013..Mineralocorticoid receptor antagonists (MRAs) may attenuate this risk. The objective of this meta-analysis was to assess the impact of MRAs on SCD in patients with left ventricular systolic dysfunction...
Acculturation and outcomes among patients with heart failurePamela N Peterson
Denver Health Medical Center, Denver, CO, USA
Circ Heart Fail 5:160-6. 2012..In particular, those who are foreign-born and who do not speak English as their primary language may have greater challenges interacting with the health care system and thus be at greater risk for adverse outcomes...
Comparison of long-term mortality across the spectrum of acute coronary syndromesLarry A Allen
Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC, USA
Am Heart J 151:1065-71. 2006..This mortality excess for MMD/NSTEMI was associated with more comorbid conditions and decreased use of basic therapies for ACS. After controlling for baseline differences, STEMI patients had the highest mortality...
Improvements in signs and symptoms during hospitalization for acute heart failure follow different patterns and depend on the measurement scales used: an international, prospective registry to evaluate the evolution of measures of disease severity in acutLarry A Allen
Division of Cardiology, University of Colorado Denver, Aurora, CO 80045, USA
J Card Fail 14:777-84. 2008..The natural evolution of signs and symptoms during acute heart failure (AHF) is poorly characterized...
Impact of medication nonadherence on hospitalizations and mortality in heart failureAshley A Fitzgerald
Division of Cardiology, Denver VA Medical Center, Denver, Colorado, USA
J Card Fail 17:664-9. 2011..Limited literature exists on the association between medication adherence and outcomes among patients with heart failure...
Aging of the United States population: impact on heart failureRebecca Vigen
Division of Cardiology, University of Colorado School of Medicine, Aurora, CO 80045, USA
Curr Heart Fail Rep 9:369-74. 2012....
Liver function abnormalities and outcome in patients with chronic heart failure: data from the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) programLarry A Allen
Division of Cardiology, University of Colorado Denver, Aurora, CO, USA
Eur J Heart Fail 11:170-7. 2009..The prevalence and importance of liver function test (LFT) abnormalities in a large contemporary cohort of heart failure patients have not been systematically evaluated...
The evolving landscape of quality measurement for heart failureAshley A Fitzgerald
Division of Cardiology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA
Ann N Y Acad Sci 1254:131-9. 2012....
Effect of left ventricular assist device placement on preexisting implantable cardioverter-defibrillator leadsAmrut V Ambardekar
Division of Cardiology and Cardiothoracic Surgery, University of Colorado Denver, Aurora, CO 80045, USA
J Card Fail 16:327-31. 2010..We investigated whether the implantation of a LVAD affects ICD function...
Care concordant with guidelines predicts decreased long-term mortality in patients with unstable angina pectoris and non-ST-elevation myocardial infarctionLarry A Allen
Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Am J Cardiol 93:1218-22. 2004..In firmly establishing the benefit of consensus guidelines, the foundation is set for efforts to improve practitioner compliance with these standards...
Patient-identified factors related to heart failure readmissionsJessica H Retrum
School of Public Affairs, Department of Health and Behavioral Sciences, University of Colorado Denver, CO, USA
Circ Cardiovasc Qual Outcomes 6:171-7. 2013..Although readmission after hospitalization for heart failure has received increasing attention, little is known about its root causes. Prior investigations have relied on administrative databases, chart review, and single-question surveys...
Performance of 3-dimensional echocardiography in measuring left ventricular volumes and ejection fraction: a systematic review and meta-analysisJennifer L Dorosz
Division of Cardiology, School of Medicine, University of Colorado Denver, Aurora, Colorado 80045, USA
J Am Coll Cardiol 59:1799-808. 2012..The primary aim of this systematic review is to objectively evaluate the test performance characteristics of three-dimensional echocardiography (3DE) in measuring left ventricular (LV) volumes and ejection fraction (EF)...
Palliative care and hospice in advanced heart failureLisa Lemond
Division of Cardiology, Department of Medicine, University of Colorado Denver, Anschutz Medical Center, Aurora, USA
Prog Cardiovasc Dis 54:168-78. 2011....
