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Genomes and GenesSpecies | L H AllenSummaryAffiliation: University of California Country: USA Publications
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Publications
Low folate status is associated with impaired cognitive function and dementia in the Sacramento Area Latino Study on AgingMarisa I Ramos
School of Medicine, Department of Medical Pathology, University of California, Davis, USA
Am J Clin Nutr 82:1346-52. 2005..CONCLUSION: RBC folate is directly associated with cognitive function scores and is inversely associated with dementia in elderly Latinos despite folic acid fortification...
Estimating the potential for vitamin A toxicity in women and young childrenLindsay H Allen
Program in International Nutrition, Department of Nutrition, University of California, Davis, CA 95616, USA
J Nutr 132:2907S-2919S. 2002..The kinetic analysis also illustrates that a constant supply of vitamin A from breast milk (and/or complementary foods) is vital for preventing depletion of liver vitamin A stores between high dose supplements...
Anemia and iron deficiency: effects on pregnancy outcomeL H Allen
Department of Nutrition, University of California, Davis 95616 8669, USA
Am J Clin Nutr 71:1280S-4S. 2000..The weight of evidence supports the advisability of routine iron supplementation during pregnancy...
Lack of hemoglobin response to iron supplementation in anemic mexican preschoolers with multiple micronutrient deficienciesL H Allen
Program in International Nutrition, the Department of Nutrition, The University of California, Davis, CA 95616 8669, USA
Am J Clin Nutr 71:1485-94. 2000..In developing countries, incomplete resolution of anemia with iron supplementation is often attributed to poor compliance or inadequate duration of supplementation, but it could result from deficiencies of other micronutrients...
Multiple micronutrients in pregnancy and lactation: an overviewLindsay H Allen
US Department of Agriculture, ARS Western Human Nutrition Research Center, and Department of Nutrition, University of California, Davis, CA, USA
Am J Clin Nutr 81:1206S-1212S. 2005....
Iron supplements: scientific issues concerning efficacy and implications for research and programsLindsay H Allen
Department of Nutrition, University of California, Davis, Davis, CA 95616, USA
J Nutr 132:813S-9S. 2002..Further work is required to clarify the purpose, delivery and outcomes of iron supplementation programs...
Interventions for micronutrient deficiency control in developing countries: past, present and futureLindsay H Allen
Department of Nutrition, University of California, Davis, CA 95616, USA
J Nutr 133:3875S-3878S. 2003..Much more communication is needed among the nutrition, agriculture and development communities to achieve improved dietary quality for poor populations...
New approaches for designing and evaluating food fortification programsLindsay H Allen
U S Department of Agriculture, ARS Western Human Nutrition Research Center, University of California, Davis, CA 95616, USA
J Nutr 136:1055-8. 2006..In summary, the design and evaluation of food fortification programs now requires a series of formative research procedures on the part of nutritionists, which were not often expected or conducted in the past...
B vitamins: proposed fortification levels for complementary foods for young childrenLindsay H Allen
Department of Nutrition, University of California, Davis, CA 95616, USA
J Nutr 133:3000S-7S. 2003..If there are losses during food preparation or concentrations of the vitamins are low in human milk, the estimates provided may need to be increased. The adequacy of these recommendations must be evaluated thoroughly...
Impact of vitamin B-12 deficiency during lactation on maternal and infant healthLindsay H Allen
Department of Nutrition, University of California, Davis 95616, USA
Adv Exp Med Biol 503:57-67. 2002
Plasma folate concentrations are associated with depressive symptoms in elderly Latina women despite folic acid fortificationMarisa I Ramos
Department of Pathology and Laboratory Medicine, University of California, Davis School of Medicine, Davis, USA
Am J Clin Nutr 80:1024-8. 2004..001). CONCLUSION: These data indicate that, despite folic acid fortification, low folate status is associated with depressive symptoms in elderly Latina women (but not elderly Latino men)...
Causes of vitamin B12 and folate deficiencyLindsay H Allen
USDA, ARS Western Human Nutrition Research Center, University of California, Davis, CA 95616, USA
Food Nutr Bull 29:S20-34; discussion S35-7. 2008..Other situations in which the risk of folate deficiency increases include lactation and alcoholism...
Supplementation with iron and riboflavin enhances dark adaptation response to vitamin A-fortified rice in iron-deficient, pregnant, nightblind Nepali womenJoanne M Graham
Program in International Nutrition, Department of Nutritional Biology, University of California Davis, Davis, CA 95616, USA
Am J Clin Nutr 85:1375-84. 2007..Iron and riboflavin affect vitamin A utilization and photoreceptor function, respectively, and pilot data in the study population showed a high prevalence of iron and riboflavin deficiencies...
Nutrition knowledge and practices, and consumption of vitamin A--rich plants by rural Nepali participants and nonparticipants in a kitchen-garden programKatharine M Jones
Program in International Nutrition, Department of Nutrition, University of California, Davis, California 95616, USA
Food Nutr Bull 26:198-208. 2005....
How common is vitamin B-12 deficiency?Lindsay H Allen
US Department of Agriculture, ARS Western Human Nutrition Research Center, University of California, Davis, Davis, CA 95616, USA
Am J Clin Nutr 89:693S-6S. 2009..However, intervention studies are still needed to assess efficacy and functional benefits of increasing intake of the amounts likely to be consumed in flour, including in elderly persons with varying degrees of gastric atrophy...
To what extent can food-based approaches improve micronutrient status?Lindsay H Allen
USDA, ARS Western Human Nutrition Research Center, 430 West Health Sciences Drive, University of California, Davis, CA 95616, USA
Asia Pac J Clin Nutr 17:103-5. 2008..Moreover, food-based strategies will improve dietary quality in general and are consistent with the global need to lower the risk of chronic disease and overweight...
Considering the case for vitamin B12 fortification of flourLindsay H Allen
USDA, ARS Western Human Nutrition Research Center, 430 W Health Sciences Drive, University of California, Davis, CA 95616, USA
Food Nutr Bull 31:S36-46. 2010..In addition, further research should evaluate the bioavailability of the vitamin from fortified flour by elderly people with food cobalamin malabsorption and gastric atrophy...
Limitations of current indicators of micronutrient statusLindsay H Allen
United States Department of Agriculture, Agricultural Research Service, Western Human Nutrition Research Center, Davis, California 95616, USA
Nutr Rev 67:S21-3. 2009..Although there have been notable breakthroughs, further improvements in methods to assess micronutrient status are urgently needed...
Provision of multiple rather than two or fewer micronutrients more effectively improves growth and other outcomes in micronutrient-deficient children and adultsLindsay H Allen
USDA, Agricultural Research Service Western Human Nutrition Research Center, Davis, CA 95616, USA
J Nutr 139:1022-30. 2009..The efficacy of MMN varies across trials, but overall there is evidence that outcomes are better than when providing < or =2 MN. The policy implications of these studies are discussed...
Impact of multiple micronutrient versus iron-folic acid supplements on maternal anemia and micronutrient status in pregnancyLindsay H Allen
U S Department of Agriculture, ARS Western Human Nutrition Research Center, University of California, Davis, California, USA
Food Nutr Bull 30:S527-32. 2009..Multiple micronutrient supplements could increase hemoglobin and improve micronutrient status of pregnant women more than iron supplements alone or iron with folic acid...
Kenyan school children have multiple micronutrient deficiencies, but increased plasma vitamin B-12 is the only detectable micronutrient response to meat or milk supplementationJonathan H Siekmann
Program in International Nutrition, University of California, Davis, CA 95616, USA
J Nutr 133:3972S-3980S. 2003..Supplementation with small amounts of meat or milk reduced the high prevalence of vitamin B-12 deficiency in these children...
Young Zanzibari children with iron deficiency, iron deficiency anemia, stunting, or malaria have lower motor activity scores and spend less time in locomotionDeanna K Olney
Program in International and Community Nutrition, University of California, Davis, CA 95616, USA
J Nutr 137:2756-62. 2007....
Effect of vitamin B12 deficiency on neurodevelopment in infants: current knowledge and possible mechanismsDaphna K Dror
Department of Nutrition at the University of California Davis, Davis, California, USA
Nutr Rev 66:250-5. 2008....
Combined iron and folic acid supplementation with or without zinc reduces time to walking unassisted among Zanzibari infants 5- to 11-mo oldDeanna K Olney
U.S. Department of Agriculture, ARS-Western Human Nutrition Research Center, Davis, CA, USA
J Nutr 136:2427-34. 2006..There were no significant treatment effects on changes in HAZ or WAZ. The effects of treatment on time to walking may have been mediated by improvements in iron status or hemoglobin, but were not mediated through improvements in growth...
Vitamin D inadequacy in pregnancy: biology, outcomes, and interventionsDaphna K Dror
USDA ARS Western Human Nutrition Research Center, Davis, California 95616, USA
Nutr Rev 68:465-77. 2010....
Selecting items for a food behavior checklist for a limited-resource audienceMarilyn S Townsend
Department of Nutrition, University of California Davis, One Shields Avenue, Davis, CA 95616, USA
J Nutr Educ Behav 35:69-77. 2003..To report 6 psychometric properties of food behavior checklist (FBC) items and then to use these properties to systematically reduce the number of items on this evaluation tool...
Homocysteine and cognitive function in the Sacramento Area Latino Study on AgingJoshua W Miller
Department of Medical Pathology, School of Medicine, University of California, Davis, USA
Am J Clin Nutr 78:441-7. 2003....
High prevalence of cobalamin deficiency in Guatemalan schoolchildren: associations with low plasma holotranscobalamin II and elevated serum methylmalonic acid and plasma homocysteine concentrationsLisa M Rogers
Department of Nutrition, Program in International Nutrition, University of California, Davis, 95616-8669, USA
Am J Clin Nutr 77:433-40. 2003..CONCLUSION: Biochemical markers of cobalamin deficiency confirmed that the cobalamin status of children with low and marginal plasma cobalamin is inadequate to support normal metabolic function...
Development of nutritionally at-risk young children is predicted by malaria, anemia, and stunting in Pemba, ZanzibarDeanna K Olney
Program in International and Community Nutrition, University of California, Davis, CA 95616, USA
J Nutr 139:763-72. 2009..e. prevention and treatment of anemia, stunting, and malaria)...
Effect of supplemental zinc on the growth and serum zinc concentrations of prepubertal children: a meta-analysis of randomized controlled trialsKenneth H Brown
Program in International Nutrition and the Department of Nutrition, University of California, Davis 95616, USA
Am J Clin Nutr 75:1062-71. 2002..Multiple studies have been carried out to assess the effect of zinc supplementation on children's growth. The results of these studies are inconsistent, and the factors responsible for these varied outcomes are unknown...
Biological mechanisms that might underlie iron's effects on fetal growth and preterm birthL H Allen
Program in International Nutrition, Department of Nutrition, University of California, Davis, CA, USA
J Nutr 131:581S-589S. 2001..It would be useful to explore these potential biological mechanisms in randomized, controlled iron supplementation trials in anemic and iron-deficient pregnant women...
Predictors of cobalamin deficiency in Guatemalan school children: diet, Helicobacter pylori, or bacterial overgrowth?Lisa M Rogers
Department of Nutrition, Program in International Nutrition, University of California, Davis, California 95616-8669, USA
J Pediatr Gastroenterol Nutr 36:27-36. 2003..CONCLUSIONS: The specific cause of cobalamin deficiency in this population remains unclear, but these results suggest that low dietary B12 intake is a risk factor and alterations in gastric secretions may also play a role...
Position of the American Dietetic Association: nutrition and lifestyle for a healthy pregnancy outcomeLucia Kaiser
Cooperative Extension, University of California, Davis, USA
J Am Diet Assoc 108:553-61. 2008..However, vitamin and mineral supplementation is appropriate for some nutrients and situations. This position paper also includes recommendations pertaining to use of alcohol, tobacco, caffeine, and illicit drugs...
Functional assessment of nutritional status: lessons learned and future challengesLindsay H Allen
Program in International Nutrition, University of California, Davis, USA
Forum Nutr 56:305-7. 2003
Prevalent vitamin B-12 deficiency in twelve-month-old Guatemalan infants is predicted by maternal B-12 deficiency and infant dietKatharine M Jones
Department of Nutrition, University of California, Davis, CA 95616, USA
J Nutr 137:1307-13. 2007..Vitamin B-12 supplementation of lactating women, food fortification, and education to improve infant's vitamin B-12 status are potential interventions that can improve the vitamin B-12 status of mothers and infants in this population...
Measurement of total vitamin B12 and holotranscobalamin, singly and in combination, in screening for metabolic vitamin B12 deficiencyJoshua W Miller
Department of Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA 95817, USA
Clin Chem 52:278-85. 2006..Measurement of both holoTC and total vitamin B12 provides a better screen for vitamin B12 deficiency than either assay alone...
Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older HispanicsM G Garrod
USDA, ARS Western Human Nutrition Research Center, Davis, CA 95817, USA
Eur J Clin Nutr 64:503-9. 2010..A common polymorphism, C776G, in the plasma B12 transport protein transcobalamin (TC), encodes for either proline or arginine at codon 259. This polymorphism may affect the affinity of TC for B12 and subsequent delivery of B12 to tissues...
Low plasma vitamin B-12 in Kenyan school children is highly prevalent and improved by supplemental animal source foodsErin D McLean
Department of Nutritional Biology, University of California, Davis, CA 95616, USA
J Nutr 137:676-82. 2007..001). The high prevalence of low plasma vitamin B-12 concentrations in these children is predicted by a low intake of ASF, and supplemental ASF improves vitamin B-12 status...
Plasma vitamin B-12 concentrations in an elderly latino population are predicted by serum gastrin concentrations and crystalline vitamin B-12 intakeAlison K Campbell
Department of Nutrition, Program in International Nutrition, University of California, Davis, CA, USA
J Nutr 133:2770-6. 2003..Crystalline vitamin B-12 intake predicted p-B12 in individuals with elevated serum gastrin, supporting IOM recommendations to increase consumption of crystalline vitamin B-12...
Advantages and limitations of iron amino acid chelates as iron fortificantsLindsay H Allen
International Nutrition, Department of Nutrition, University of California, Davis 95616, USA
Nutr Rev 60:S18-21; discussion S45. 2002
Animal source foods improve dietary quality, micronutrient status, growth and cognitive function in Kenyan school children: background, study design and baseline findingsCharlotte G Neumann
Department of Community Health Sciences and Pediatrics, Schools of Public Health and Medicine, University of California, Los Angeles, CA, USA
J Nutr 133:3941S-3949S. 2003..Hierarchical linear random effects modeling was used for analysis of outcomes...
Metabolic evidence of vitamin B-12 deficiency, including high homocysteine and methylmalonic acid and low holotranscobalamin, is more pronounced in older adults with elevated plasma folateJoshua W Miller
School of Medicine, Department of Medical Pathology and Laboratory Medicine, University of California, Davis, CA, USA
Am J Clin Nutr 90:1586-92. 2009..These findings await confirmation in other populations...
Folate and vitamin B12 status in the AmericasLindsay H Allen
Western Human Nutrition Research Center and Program in International Nutrition, University of California, Davis, CA 95616, USA
Nutr Rev 62:S29-33; discussion S34. 2004..Low plasma folate concentrations were less common. It is hypothesized that vitamin B12 deficiency may result from a low intake of animal source foods, while a higher intake of refined flour may result in low plasma folate...
Spot ferritin assay for serum samples dried on filter paperN Ahluwalia
Department of Nutrition, Pennsylvania State University, University Park 16802, USA
Am J Clin Nutr 67:88-92. 1998..Capillary blood can be sampled to avoid the costs and concerns associated with venipuncture and spotted serum samples can be stored at room temperature for > or = 4 wk, eliminating the need for freezing during storage and transportation...
Priority areas for research on the intake, composition, and health effects of tree nuts and peanutsLindsay H Allen
USDA, ARS Western Human Nutrition Research Center, University of California, Davis, CA 95616, USA
J Nutr 138:1763S-1765S. 2008..Information is needed on nut-induced allergic reactions, including their prevalence and consequences, causes of sensitization, biomarkers of severe reactions, and cross-reactivity to different types of nuts...
Fraction of total plasma vitamin B12 bound to transcobalamin correlates with cognitive function in elderly Latinos with depressive symptomsMarjorie G Garrod
Department of Medical Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, CA, USA
Clin Chem 54:1210-7. 2008..The fraction of total plasma vitamin B(12) bound to transcobalamin (holoTC/B12 ratio) may reflect tissue levels of the vitamin, but its clinical relevance is unclear...
Comparison of plasma ferritin concentration with the ratio of plasma transferrin receptor to ferritin in estimating body iron stores: results of 4 intervention trialsZhenyu Yang
Program in International and Community Nutrition, Department of Nutrition, University of California, Davis, Davis, CA 95616, USA
Am J Clin Nutr 87:1892-8. 2008..Efforts to develop global programs for the control of iron deficiency require simple, low-cost, and accurate indicators of iron status...
Titers of antibody to common pathogens: relation to food-based interventions in rural Kenyan schoolchildrenJonathan H Siekmann
Department of Nutrition, University of California, Davis 95616, USA
Am J Clin Nutr 77:242-9. 2003..CONCLUSIONS: A large battery of immune assays can be performed on microvolumes of sera. Furthermore, despite evidence of malnutrition, children do develop significant antibody-mediated responses to common pathogens...
Erythrocyte riboflavin for the detection of riboflavin deficiency in pregnant Nepali womenJoanne M Graham
United States Department of Agriculture--Western Human Nutrition Research Center, University of California, Davis, 95616, USA
Clin Chem 51:2162-5. 2005
Diet and iron status of nonpregnant women in rural Central MexicoJeffrey R Backstrand
Department of Nutrition and Food Studies, New York University, New York, USA
Am J Clin Nutr 76:156-64. 2002..Few studies have examined the relation of iron status to diet in populations from developing countries with high levels of iron deficiency and diets of poor quality...
Review of the magnitude of folate and vitamin B12 deficiencies worldwideErin McLean
Department of Nutrition for Health and Development, World Health Organization, Geneva, Switzerland
Food Nutr Bull 29:S38-51. 2008..More representative data and more consistent use of thresholds to define deficiency are needed in order to assess whether folate and vitamin B12 deficiencies are a public health problem...
The efficacy of a local ascorbic acid-rich food in improving iron absorption from Mexican diets: a field study using stable isotopesMargarita Diaz
Facultad de Ciencias Naturales, Universidad Autonoma de Queretaro, Queretaro, Mexico
Am J Clin Nutr 78:436-40. 2003..One potentially sustainable approach to improving iron status at the community level is to encourage the consumption of local ascorbic acid-rich foods, in conjunction with meals high in nonheme iron...
Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on AgingMary N Haan
Epidemiology Program, School of Public Health, University of Michigan, Ann Arbor, MI 48104, USA
Am J Clin Nutr 85:511-7. 2007..High concentrations of homocysteine have been linked to a greater risk of Alzheimer disease, dementia, and cognitive decline...
Maternal and child undernutrition: global and regional exposures and health consequencesRobert E Black
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Lancet 371:243-60. 2008
Causes of nutrition-related public health problems of preschool children: available dietLindsay H Allen
J Pediatr Gastroenterol Nutr 43:S8-12. 2006..Although much is now known about the role of inadequate diets in preschooler malnutrition, on a global scale the ability of households to apply this knowledge to improve the diets of their children is still limited...
Nutritional importance of animal source foodsSuzanne P Murphy
Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA
J Nutr 133:3932S-3935S. 2003..An index that estimates nutrient adequacy based on adherence to such food guide recommendations may provide a useful method of quickly evaluating dietary quality in both developing and developed countries...
Ascorbic acid from lime juice does not improve the iron status of iron-deficient women in rural MexicoOlga P Garcia
, , Mexico City
Am J Clin Nutr 78:267-73. 2003..CONCLUSION: Increasing dietary AA by 25 mg at each of 2 meals/d did not improve iron status in iron-deficient women consuming diets high in phytate and nonheme iron...
Application of nutrient intake values (NIVs)Hester H Vorster
Faculty of Health Sciences, NWU Potchefstroom Campus, Potchefstroom 2520, South Africa
Food Nutr Bull 28:S116-22. 2007..Applications in both developed and developing countries are also described. In summary, NIVs are the scientific backbone of all aspects of nutrition policy in countries and regions worldwide...
